The document is a question bank for M.Pharmacy students focused on Pharmaceutics and Drug Delivery Systems, covering various units. It includes essay questions and short notes related to sustained release, rate-controlled drug delivery systems, and ocular drug delivery systems, detailing approaches, mechanisms, and polymers involved. The document is extracted from previous university papers to aid students in their exam preparation.

1. DR. A. SUMATHI, PROFESSOR OF PHARMACEUTICS 1
MPH PAPER II (102T)
Question Bank Extracted from Previous University Question Papers
M.PHARMACY DEGREE SEMESTER-I PHARMACEUTICS
DRUG DELIVERY SYSTEMS
Unit 1
Essay (20 Marks)
1. Explain the various approaches used in the design of oral sustained release or controlled
release drug delivery system.
2. Explain the physiochemical and biological factors influencing the design of sustained
release dosage forms
3. Discuss about mechanism of drug release from CR/SR formulation
4. Give a detailed account on the various polymers used in the formulation of sustained or
controlled release drug delivery system (OR)
Classify and explain in detail about polymers. Write the applications of polymers in
controlled drug delivery systems (OR)
Discuss the classification and applications of polymers in drug delivery
Short Notes (5 marks)
1. Physiochemical properties affecting sustained release preparations (OR)
Physicochemical factors influencing SR/CR formulation
2. Biological factors influencing SR/CR formulations
3. Mechanism of Drug Delivery from SR/CR formulation
4. Advantages and Disadvantages of Sustained release formulations
5. Diffusion controlled drug delivery system.
6. Biodegradable polymers**
7. Natural Polymers
8. Customized drug delivery systems*
9. Personalized medicines*
10. Pharmacogenetics
11. Categories of patients for personalized medicine
12. 3D printing of Pharmaceuticals*
13. Bioelectronic medicines*
14. Telepharmacy**
(Note: *Represents Number of Occurrence of Questions in Previous Year University Question Papers)

2. DR. A. SUMATHI, PROFESSOR OF PHARMACEUTICS 2
MPH PAPER II (102T)
Question Bank Extracted from Previous University Question Papers
M.PHARMACY DEGREE SEMESTER-I PHARMACEUTICS
DRUG DELIVERY SYSTEMS
Unit 2
Essay (20 Marks)
1. Explain the concepts and design of rate-controlled drug delivery systems (OR)
Explain the principle and approaches for formulation of rate-controlled DDS
2. Describe formulations of mechanically activated, pH activated and Osmotic activated rate-
controlled Drug Delivery system
3. Explain about osmotic activated drug delivery system
Short Notes (5 marks)
15. Activation modulated drug delivery systems*
16. pH activated drug delivery systems
17. Enzyme activated drug delivery systems
18. Osmotic activated drug delivery system
19. Elementary osmotic pump
20. Environmentally responsive polymers
21. Feedback regulated drug delivery system
22. Chemically activated drug delivery systems
(Note: *Represents Number of Occurrence of Questions in Previous Year University Question Papers)

3. DR. A. SUMATHI, PROFESSOR OF PHARMACEUTICS 3
MPH PAPER II (102T)
Question Bank Extracted from Previous University Question Papers
M.PHARMACY DEGREE SEMESTER-I PHARMACEUTICS
DRUG DELIVERY SYSTEMS
Unit 4
Essay (20 Marks)
1. Explain / Describe in detail about Ocular Drug Delivery system*
Short Notes (5 marks)
1. Barriers of drug permeation in ocular drug delivery system**
2. Ophthalmic drug delivery systems
3. Formulation approaches for ocular drug delivery system
4. Occuserts / Ocusert systems****
(Note: *Represents Number of Occurrence of Questions in Previous Year University Question Papers)