The document is a question bank compiled by Dr. A. Sumathi for M.Pharmacy students, covering various topics related to pharmaceutics, including computer-aided drug development, optimization techniques, and artificial intelligence applications in the pharmaceutical industry. It outlines detailed essay and short note questions across multiple units focused on formulation development, biopharmaceutical characterization, clinical data management, and automation in pharmacy. The document provides a structured approach to exam preparation through previous university questions.

1. DR. A. SUMATHI, PROFESSOR OF PHARMACEUTICS 1
PAPER III (MPH 203T)
Question Bank Extracted from Previous University Question Papers
M.PHARMACY DEGREE SEMESTER-II PHARMACEUTICS
COMPUTER AIDED DRUG DEVELOPMENT
Essay (20 Marks)
Unit 3
1. Discuss the optimization parameters and different optimization techniques in formulation
development.
2. Define optimization. Explain the significance of optimization and factorial design.
3. Explain the experimental design in optimization of pharmaceutical formulations.
4. Explain in detail about computer aided formulation development.
Unit 4
5. Write in detail about Computer Aided Biopharmaceutical characterization in
Gastrointestinal absorption simulation.
6. Computer simulation in whole organism and isolated tissues
Unit 5
7. Explain the role of computers in clinical data collection and management*
8. Describe about clinical data collection systems.
9. Applications of computer in various Intellectual Property Rights of Pharmaceutical R & D
Short Notes (5 marks)
Unit 3
1. Explain about Optimization Parameters
2. Variables and confounding in optimization
3. Factorial design
4. Discuss the role of computers in pharmaceutical formulation
5. Application of factorial design in development of pharmaceutical emulsion (or)
Applications of computer aided techniques in development of pharmaceutical emulsions
6. Applications of computer in patents
7. Common issues of computer ethics in Research and Development
8. Computers in Market analysis***
Unit 4
9. Use of Computers in Biopharmaceutical characterization
10. Write a note on Virtual trial
11. Different levels of In-vitro and In-vivo correlations***

2. DR. A. SUMATHI, PROFESSOR OF PHARMACEUTICS 2
PAPER III (MPH 203T)
Question Bank Extracted from Previous University Question Papers
12. Biowaiver considerations** (or)
What are the bio waiver considerations to be considered to get the exception for In vivo
studies?
13. Write the importance of computer simulation in pharmaco-dynamics
14. Biomedical simulations (Pharmacokinetic & Pharmacodynamic)
15. Computer simulations in whole organism*
16. Computers in Clinical Data development (or)
Computers in Clinical development
17. Computer simulations in Gastro intestinal absorption*
Unit 5
18. Artificial intelligence and Robotics
19. What is artificial intelligence? Mention its applications*
20. Applications of artificial intelligence in pharmaceutical industry
21. Current Challenges and Future Directions of Artificial Intelligence
22. Robotics and its application in pharmacy*
23. Write about Pharmaceutical Automation
24. Explain pharmaceutical automation role in dosage form manufacturing (or)
Pharmaceutical automation in tablet manufacturing
25. Write the benefits of pharmaceutical automation in packaging.
26. Computational fluid dynamics
27. Applications of Computational fluid dynamics (or)
Describe the applications of computational fluid dynamics in pharmacy.
(Note: *Represents Number of Occurrence of Questions in Previous Year University Question Papers)