SlideShare a Scribd company logo
MITRAL STENOSIS
AETIOLOGY
• Almost always rheumatic in origin.
• In older people it can be caused by heavy
calcification of mitral valve apparatus.
• Congenital mitral valve stenosis.
• SLE,rheumatoid arthritis,left atrial myxoma.
• Pure MS occurs in 40% of all patients with RHD and
a h/o RF.
PATHOPHYSIOLOGY
Fusion of mitral commisures
↓
restricted opening of mitral valve
↓
“fish mouth” shape of mitral valve orifice
Thickening, fusion and shortening of the chordae or papillary
muscles ,valvular cusps become rigid
↓
funnel-shaped change of valve apparatus
PATHOPHYSIOLOGY
• In rheumatic mitral stenosis, the mitral valve orifice is slowly
diminished by fibrosis,& calcification.
• Normal area of mitral valve is 4-6 cm2
• Reduced to <2cm2.
• Flow of blood from LA to LV is restricted.
• Left atrial pressure rises.
• Leads to pulmonary venous congestion & breathlessness.
• Dilatation & hypertrophy of LA.
Effect of elevated LAP on pulmonary circulation
• The elevated LAP in turn raises pulmonary venous and
capillary pressures (PVP, PCP).
LAP↑ → PVP↑→ PCP↑→ Exertional Dyspnea
Lung compliance↓
Pulmonary hypertension results from:
• 1. Passive backward transmission of the elevated LAP.
• 2. Reactive pulmonary arteriolar constriction, which
presumably is triggered by left atrial and pulmonary venous
hypertension,
• 3. Organic obliterative changes in the pulmonary vascular
bed, which may be considered to be a complication of
longstanding and severe MS.
Pulmonary HTN leads to
• Right ventricular hypertrophy and dilatation.
• Tricuspid regurgitation.
• Right heart failure.
Atrial fibrillation due to progressive dilatation of LA
is very common.
•Clinical manifestations
symptoms
Dyspnea: principle syndrome. Occurs at an early
stage. Precipitated by
Exertion, excitement
Paroxysmal AF
Pregnancy
Thyrotoxicosis
AT LATER STAGE- ORTHOPNEA,PND
• Hemoptysis (Secondary to pulmonary venous
HTN)
• Fatigue(low cardiac output)
• Chest pain
• Cough
• Edema,ascites(Right heart failure)
• Palpitation (AF)
SIGNS
• Malar flush with pinched and blue facies.
• Atrial fibrillation
• Pulmonary edema,effusions(raised pulmonary
capillary pressure).
 AUSCULTATION
Loud first heart sound,opening snap.
Mid diastolic murmur.
Crepitation
INVESTIGATION
Electrocardiography (ECG)
• P wave suggests Left atrial enlargement
• Mitral valve P wave
• P-wave duration in lead II > 0.12 s
• P wave upright in lead V1
• QRS complex usually normal
• Right ventricular hypertrophy :tall R waves in V1-V3.
• Arrhythmia.
• Premature atrial contraction → atrial fibrillation
X-RAY
• straightening of left upper border of heart.
• Prominence of main pulmonary arteries.
• Posterior displacement of oesophagus by
enlarged LA.
• ECHO
• DOPPLER
• CARDIAC CATHETERISATION
MANAGEMENT
• Penicillin prophylaxis for secondary prevention of RF for at
risk patients.
• Restrict sodium intake, and take oral diuretics.
• Beta blockers.
• CCB-verapamil,diltiazem.
• Digitalis glycoside to reduce ventricular rate in patient with
AF.
• Warfarin.
CRITERIA FOR MITRAL
VALVULOPLASTY
• SIGNIFICANT SYMPTOMS
• ISLOTED MITRAL STENOSIS
• NO (OR TRIVIAL) MITRAL REGURGITATION
• MOBILE,NON CALCIFIED VALVE ON ECHO
• LA FREE OF THROMBUS
THANK YOU

More Related Content

What's hot

Mitral valve
Mitral valveMitral valve
Mitral valve
Uphar Gupta
 
Aortic regurgitation
Aortic regurgitationAortic regurgitation
Aortic regurgitation
Pratap Tiwari
 
Aortic regurgitation
Aortic regurgitationAortic regurgitation
Aortic regurgitation
Satish Kamboj
 
Mitral valve regurgitation
Mitral valve regurgitationMitral valve regurgitation
Mitral valve regurgitationMohammad Aladam
 
Mitral stenosis
Mitral stenosisMitral stenosis
Mitral stenosis
Pratap Tiwari
 
Restrictive cardiomyopathy
Restrictive cardiomyopathyRestrictive cardiomyopathy
Restrictive cardiomyopathy
Nizam Uddin
 
Constrictive pericarditis
Constrictive pericarditisConstrictive pericarditis
Constrictive pericarditis
Waqas Khalid
 
Mitral stenosis
Mitral stenosisMitral stenosis
Mitral stenosis
Dharmraj Singh
 
Cardiomyopathy
CardiomyopathyCardiomyopathy
Cardiomyopathy
Amphetaminesd
 
Aortic stenosis
Aortic stenosisAortic stenosis
Aortic stenosis
Kavindya Fernando
 
Mitral valve stenosis powerpoint
Mitral valve stenosis powerpointMitral valve stenosis powerpoint
Mitral valve stenosis powerpoint
kayanalevy25
 
Mitral regurgitation
Mitral regurgitationMitral regurgitation
Mitral regurgitation
Diaa Srahin
 
Heart failure
Heart failureHeart failure
Heart failure
ArthurMpower
 
Dilated cardiomyopathy
Dilated cardiomyopathyDilated cardiomyopathy
Dilated cardiomyopathy
Lazoi Lifecare Private Limited
 
Valvular heart disease
Valvular heart diseaseValvular heart disease
Valvular heart disease
MR. JAGDISH SAMBAD
 
Aortic anurysm
Aortic anurysmAortic anurysm
Aortic anurysm
Monika Devi NR
 
Pericardial diseases
Pericardial  diseasesPericardial  diseases
Pericardial diseases
ikramdr01
 
Sick sinus syndrome
Sick sinus syndrome Sick sinus syndrome
Sick sinus syndrome
Rawalpindi Medical College
 
Constrictive pericarditis
Constrictive pericarditis Constrictive pericarditis
Constrictive pericarditis
Ramachandra Barik
 
Mitral regurgitation
Mitral regurgitationMitral regurgitation
Mitral regurgitation
Aaina Firdos
 

What's hot (20)

Mitral valve
Mitral valveMitral valve
Mitral valve
 
Aortic regurgitation
Aortic regurgitationAortic regurgitation
Aortic regurgitation
 
Aortic regurgitation
Aortic regurgitationAortic regurgitation
Aortic regurgitation
 
Mitral valve regurgitation
Mitral valve regurgitationMitral valve regurgitation
Mitral valve regurgitation
 
Mitral stenosis
Mitral stenosisMitral stenosis
Mitral stenosis
 
Restrictive cardiomyopathy
Restrictive cardiomyopathyRestrictive cardiomyopathy
Restrictive cardiomyopathy
 
Constrictive pericarditis
Constrictive pericarditisConstrictive pericarditis
Constrictive pericarditis
 
Mitral stenosis
Mitral stenosisMitral stenosis
Mitral stenosis
 
Cardiomyopathy
CardiomyopathyCardiomyopathy
Cardiomyopathy
 
Aortic stenosis
Aortic stenosisAortic stenosis
Aortic stenosis
 
Mitral valve stenosis powerpoint
Mitral valve stenosis powerpointMitral valve stenosis powerpoint
Mitral valve stenosis powerpoint
 
Mitral regurgitation
Mitral regurgitationMitral regurgitation
Mitral regurgitation
 
Heart failure
Heart failureHeart failure
Heart failure
 
Dilated cardiomyopathy
Dilated cardiomyopathyDilated cardiomyopathy
Dilated cardiomyopathy
 
Valvular heart disease
Valvular heart diseaseValvular heart disease
Valvular heart disease
 
Aortic anurysm
Aortic anurysmAortic anurysm
Aortic anurysm
 
Pericardial diseases
Pericardial  diseasesPericardial  diseases
Pericardial diseases
 
Sick sinus syndrome
Sick sinus syndrome Sick sinus syndrome
Sick sinus syndrome
 
Constrictive pericarditis
Constrictive pericarditis Constrictive pericarditis
Constrictive pericarditis
 
Mitral regurgitation
Mitral regurgitationMitral regurgitation
Mitral regurgitation
 

Similar to Mitral stenosis

4.RHD CVS.ppt
4.RHD  CVS.ppt4.RHD  CVS.ppt
4.RHD CVS.ppt
MaryannNyambura
 
Pericardial compressive syndromes
Pericardial compressive syndromesPericardial compressive syndromes
Pericardial compressive syndromes
SLNursesAssociation
 
Valvular Heart Disease.pptx
Valvular Heart Disease.pptxValvular Heart Disease.pptx
Valvular Heart Disease.pptx
Shilpasree Saha
 
Valvular heart diseases
Valvular heart diseasesValvular heart diseases
Valvular heart diseases
abelfelege
 
Congenital heart defects
Congenital heart defectsCongenital heart defects
Congenital heart defects
kajal sansoya
 
Anesthesia Management in Aortic Regurgitation
Anesthesia Management in Aortic RegurgitationAnesthesia Management in Aortic Regurgitation
Anesthesia Management in Aortic Regurgitation
Dr. Harshil Joshi
 
MED Cvs
MED CvsMED Cvs
MED CvsO J
 
CHRONIC RHEUMATIC FEVER.pptx
CHRONIC RHEUMATIC FEVER.pptxCHRONIC RHEUMATIC FEVER.pptx
CHRONIC RHEUMATIC FEVER.pptx
miroofafrika
 
Mitral stenosis.pptx
Mitral stenosis.pptxMitral stenosis.pptx
Mitral stenosis.pptx
Manoj Aryal
 
aorticregurgitation anuradha mam.docx
aorticregurgitation anuradha mam.docxaorticregurgitation anuradha mam.docx
aorticregurgitation anuradha mam.docx
MayureshChavan16
 
Valvular diseases
Valvular diseasesValvular diseases
Valvular diseases
anishkumar123
 
Pericardial diseases
Pericardial diseasesPericardial diseases
Pericardial diseases
DrArpan Chouhan
 
Valvular Heart Disease & Anaesthetic Implications
Valvular Heart Disease & Anaesthetic ImplicationsValvular Heart Disease & Anaesthetic Implications
Valvular Heart Disease & Anaesthetic Implications
Dr.Daber Pareed
 
PATHOLOGY CONGENITAL HEART DISEASE IN CHILDREN
PATHOLOGY CONGENITAL HEART DISEASE IN CHILDRENPATHOLOGY CONGENITAL HEART DISEASE IN CHILDREN
PATHOLOGY CONGENITAL HEART DISEASE IN CHILDREN
Chandler Huthey
 
Tetralogy of Fallot (TOF)
Tetralogy of Fallot (TOF)Tetralogy of Fallot (TOF)
Tetralogy of Fallot (TOF)
Dr.Sayeedur Rumi
 
mitral s.pdf
mitral s.pdfmitral s.pdf
mitral s.pdf
HibaP5
 
Valvular heart disease
Valvular heart disease Valvular heart disease
Valvular heart disease
BPT4thyearJamiaMilli
 
CONGENITAL HEART DISEASE LECTURE NOTES MD3.pptx
CONGENITAL HEART DISEASE LECTURE NOTES MD3.pptxCONGENITAL HEART DISEASE LECTURE NOTES MD3.pptx
CONGENITAL HEART DISEASE LECTURE NOTES MD3.pptx
ErhardRutakulemberwa
 
Hypertensive heart disease
Hypertensive heart diseaseHypertensive heart disease
Hypertensive heart diseaseimrana tanvir
 

Similar to Mitral stenosis (20)

4.RHD CVS.ppt
4.RHD  CVS.ppt4.RHD  CVS.ppt
4.RHD CVS.ppt
 
Pericardial compressive syndromes
Pericardial compressive syndromesPericardial compressive syndromes
Pericardial compressive syndromes
 
Valvular Heart Disease.pptx
Valvular Heart Disease.pptxValvular Heart Disease.pptx
Valvular Heart Disease.pptx
 
Valvular heart diseases
Valvular heart diseasesValvular heart diseases
Valvular heart diseases
 
Congenital heart defects
Congenital heart defectsCongenital heart defects
Congenital heart defects
 
Anesthesia Management in Aortic Regurgitation
Anesthesia Management in Aortic RegurgitationAnesthesia Management in Aortic Regurgitation
Anesthesia Management in Aortic Regurgitation
 
Cyanotic Heart Diseases
Cyanotic Heart DiseasesCyanotic Heart Diseases
Cyanotic Heart Diseases
 
MED Cvs
MED CvsMED Cvs
MED Cvs
 
CHRONIC RHEUMATIC FEVER.pptx
CHRONIC RHEUMATIC FEVER.pptxCHRONIC RHEUMATIC FEVER.pptx
CHRONIC RHEUMATIC FEVER.pptx
 
Mitral stenosis.pptx
Mitral stenosis.pptxMitral stenosis.pptx
Mitral stenosis.pptx
 
aorticregurgitation anuradha mam.docx
aorticregurgitation anuradha mam.docxaorticregurgitation anuradha mam.docx
aorticregurgitation anuradha mam.docx
 
Valvular diseases
Valvular diseasesValvular diseases
Valvular diseases
 
Pericardial diseases
Pericardial diseasesPericardial diseases
Pericardial diseases
 
Valvular Heart Disease & Anaesthetic Implications
Valvular Heart Disease & Anaesthetic ImplicationsValvular Heart Disease & Anaesthetic Implications
Valvular Heart Disease & Anaesthetic Implications
 
PATHOLOGY CONGENITAL HEART DISEASE IN CHILDREN
PATHOLOGY CONGENITAL HEART DISEASE IN CHILDRENPATHOLOGY CONGENITAL HEART DISEASE IN CHILDREN
PATHOLOGY CONGENITAL HEART DISEASE IN CHILDREN
 
Tetralogy of Fallot (TOF)
Tetralogy of Fallot (TOF)Tetralogy of Fallot (TOF)
Tetralogy of Fallot (TOF)
 
mitral s.pdf
mitral s.pdfmitral s.pdf
mitral s.pdf
 
Valvular heart disease
Valvular heart disease Valvular heart disease
Valvular heart disease
 
CONGENITAL HEART DISEASE LECTURE NOTES MD3.pptx
CONGENITAL HEART DISEASE LECTURE NOTES MD3.pptxCONGENITAL HEART DISEASE LECTURE NOTES MD3.pptx
CONGENITAL HEART DISEASE LECTURE NOTES MD3.pptx
 
Hypertensive heart disease
Hypertensive heart diseaseHypertensive heart disease
Hypertensive heart disease
 

Recently uploaded

aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
siemaillard
 
Operation Blue Star - Saka Neela Tara
Operation Blue Star   -  Saka Neela TaraOperation Blue Star   -  Saka Neela Tara
Operation Blue Star - Saka Neela Tara
Balvir Singh
 
The approach at University of Liverpool.pptx
The approach at University of Liverpool.pptxThe approach at University of Liverpool.pptx
The approach at University of Liverpool.pptx
Jisc
 
Palestine last event orientationfvgnh .pptx
Palestine last event orientationfvgnh .pptxPalestine last event orientationfvgnh .pptx
Palestine last event orientationfvgnh .pptx
RaedMohamed3
 
Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345
beazzy04
 
Template Jadual Bertugas Kelas (Boleh Edit)
Template Jadual Bertugas Kelas (Boleh Edit)Template Jadual Bertugas Kelas (Boleh Edit)
Template Jadual Bertugas Kelas (Boleh Edit)
rosedainty
 
Overview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with MechanismOverview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with Mechanism
DeeptiGupta154
 
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdf
Welcome to TechSoup   New Member Orientation and Q&A (May 2024).pdfWelcome to TechSoup   New Member Orientation and Q&A (May 2024).pdf
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdf
TechSoup
 
How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17
Celine George
 
How libraries can support authors with open access requirements for UKRI fund...
How libraries can support authors with open access requirements for UKRI fund...How libraries can support authors with open access requirements for UKRI fund...
How libraries can support authors with open access requirements for UKRI fund...
Jisc
 
2024.06.01 Introducing a competency framework for languag learning materials ...
2024.06.01 Introducing a competency framework for languag learning materials ...2024.06.01 Introducing a competency framework for languag learning materials ...
2024.06.01 Introducing a competency framework for languag learning materials ...
Sandy Millin
 
Digital Tools and AI for Teaching Learning and Research
Digital Tools and AI for Teaching Learning and ResearchDigital Tools and AI for Teaching Learning and Research
Digital Tools and AI for Teaching Learning and Research
Vikramjit Singh
 
How to Split Bills in the Odoo 17 POS Module
How to Split Bills in the Odoo 17 POS ModuleHow to Split Bills in the Odoo 17 POS Module
How to Split Bills in the Odoo 17 POS Module
Celine George
 
Language Across the Curriculm LAC B.Ed.
Language Across the  Curriculm LAC B.Ed.Language Across the  Curriculm LAC B.Ed.
Language Across the Curriculm LAC B.Ed.
Atul Kumar Singh
 
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXXPhrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
MIRIAMSALINAS13
 
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCECLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
BhavyaRajput3
 
Cambridge International AS A Level Biology Coursebook - EBook (MaryFosbery J...
Cambridge International AS  A Level Biology Coursebook - EBook (MaryFosbery J...Cambridge International AS  A Level Biology Coursebook - EBook (MaryFosbery J...
Cambridge International AS A Level Biology Coursebook - EBook (MaryFosbery J...
AzmatAli747758
 
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxStudents, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
EduSkills OECD
 
Fish and Chips - have they had their chips
Fish and Chips - have they had their chipsFish and Chips - have they had their chips
Fish and Chips - have they had their chips
GeoBlogs
 
Supporting (UKRI) OA monographs at Salford.pptx
Supporting (UKRI) OA monographs at Salford.pptxSupporting (UKRI) OA monographs at Salford.pptx
Supporting (UKRI) OA monographs at Salford.pptx
Jisc
 

Recently uploaded (20)

aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
 
Operation Blue Star - Saka Neela Tara
Operation Blue Star   -  Saka Neela TaraOperation Blue Star   -  Saka Neela Tara
Operation Blue Star - Saka Neela Tara
 
The approach at University of Liverpool.pptx
The approach at University of Liverpool.pptxThe approach at University of Liverpool.pptx
The approach at University of Liverpool.pptx
 
Palestine last event orientationfvgnh .pptx
Palestine last event orientationfvgnh .pptxPalestine last event orientationfvgnh .pptx
Palestine last event orientationfvgnh .pptx
 
Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345
 
Template Jadual Bertugas Kelas (Boleh Edit)
Template Jadual Bertugas Kelas (Boleh Edit)Template Jadual Bertugas Kelas (Boleh Edit)
Template Jadual Bertugas Kelas (Boleh Edit)
 
Overview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with MechanismOverview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with Mechanism
 
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdf
Welcome to TechSoup   New Member Orientation and Q&A (May 2024).pdfWelcome to TechSoup   New Member Orientation and Q&A (May 2024).pdf
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdf
 
How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17
 
How libraries can support authors with open access requirements for UKRI fund...
How libraries can support authors with open access requirements for UKRI fund...How libraries can support authors with open access requirements for UKRI fund...
How libraries can support authors with open access requirements for UKRI fund...
 
2024.06.01 Introducing a competency framework for languag learning materials ...
2024.06.01 Introducing a competency framework for languag learning materials ...2024.06.01 Introducing a competency framework for languag learning materials ...
2024.06.01 Introducing a competency framework for languag learning materials ...
 
Digital Tools and AI for Teaching Learning and Research
Digital Tools and AI for Teaching Learning and ResearchDigital Tools and AI for Teaching Learning and Research
Digital Tools and AI for Teaching Learning and Research
 
How to Split Bills in the Odoo 17 POS Module
How to Split Bills in the Odoo 17 POS ModuleHow to Split Bills in the Odoo 17 POS Module
How to Split Bills in the Odoo 17 POS Module
 
Language Across the Curriculm LAC B.Ed.
Language Across the  Curriculm LAC B.Ed.Language Across the  Curriculm LAC B.Ed.
Language Across the Curriculm LAC B.Ed.
 
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXXPhrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
 
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCECLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
 
Cambridge International AS A Level Biology Coursebook - EBook (MaryFosbery J...
Cambridge International AS  A Level Biology Coursebook - EBook (MaryFosbery J...Cambridge International AS  A Level Biology Coursebook - EBook (MaryFosbery J...
Cambridge International AS A Level Biology Coursebook - EBook (MaryFosbery J...
 
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxStudents, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
 
Fish and Chips - have they had their chips
Fish and Chips - have they had their chipsFish and Chips - have they had their chips
Fish and Chips - have they had their chips
 
Supporting (UKRI) OA monographs at Salford.pptx
Supporting (UKRI) OA monographs at Salford.pptxSupporting (UKRI) OA monographs at Salford.pptx
Supporting (UKRI) OA monographs at Salford.pptx
 

Mitral stenosis

  • 2. AETIOLOGY • Almost always rheumatic in origin. • In older people it can be caused by heavy calcification of mitral valve apparatus. • Congenital mitral valve stenosis. • SLE,rheumatoid arthritis,left atrial myxoma. • Pure MS occurs in 40% of all patients with RHD and a h/o RF.
  • 3.
  • 4. PATHOPHYSIOLOGY Fusion of mitral commisures ↓ restricted opening of mitral valve ↓ “fish mouth” shape of mitral valve orifice Thickening, fusion and shortening of the chordae or papillary muscles ,valvular cusps become rigid ↓ funnel-shaped change of valve apparatus
  • 5.
  • 6.
  • 7. PATHOPHYSIOLOGY • In rheumatic mitral stenosis, the mitral valve orifice is slowly diminished by fibrosis,& calcification. • Normal area of mitral valve is 4-6 cm2 • Reduced to <2cm2. • Flow of blood from LA to LV is restricted. • Left atrial pressure rises. • Leads to pulmonary venous congestion & breathlessness. • Dilatation & hypertrophy of LA.
  • 8.
  • 9. Effect of elevated LAP on pulmonary circulation • The elevated LAP in turn raises pulmonary venous and capillary pressures (PVP, PCP). LAP↑ → PVP↑→ PCP↑→ Exertional Dyspnea Lung compliance↓ Pulmonary hypertension results from: • 1. Passive backward transmission of the elevated LAP. • 2. Reactive pulmonary arteriolar constriction, which presumably is triggered by left atrial and pulmonary venous hypertension, • 3. Organic obliterative changes in the pulmonary vascular bed, which may be considered to be a complication of longstanding and severe MS.
  • 10. Pulmonary HTN leads to • Right ventricular hypertrophy and dilatation. • Tricuspid regurgitation. • Right heart failure. Atrial fibrillation due to progressive dilatation of LA is very common.
  • 11. •Clinical manifestations symptoms Dyspnea: principle syndrome. Occurs at an early stage. Precipitated by Exertion, excitement Paroxysmal AF Pregnancy Thyrotoxicosis AT LATER STAGE- ORTHOPNEA,PND
  • 12. • Hemoptysis (Secondary to pulmonary venous HTN) • Fatigue(low cardiac output) • Chest pain • Cough • Edema,ascites(Right heart failure) • Palpitation (AF)
  • 13. SIGNS • Malar flush with pinched and blue facies. • Atrial fibrillation • Pulmonary edema,effusions(raised pulmonary capillary pressure).  AUSCULTATION Loud first heart sound,opening snap. Mid diastolic murmur. Crepitation
  • 14. INVESTIGATION Electrocardiography (ECG) • P wave suggests Left atrial enlargement • Mitral valve P wave • P-wave duration in lead II > 0.12 s • P wave upright in lead V1 • QRS complex usually normal • Right ventricular hypertrophy :tall R waves in V1-V3. • Arrhythmia. • Premature atrial contraction → atrial fibrillation
  • 15. X-RAY • straightening of left upper border of heart. • Prominence of main pulmonary arteries. • Posterior displacement of oesophagus by enlarged LA.
  • 16.
  • 17. • ECHO • DOPPLER • CARDIAC CATHETERISATION
  • 18.
  • 19. MANAGEMENT • Penicillin prophylaxis for secondary prevention of RF for at risk patients. • Restrict sodium intake, and take oral diuretics. • Beta blockers. • CCB-verapamil,diltiazem. • Digitalis glycoside to reduce ventricular rate in patient with AF. • Warfarin.
  • 20. CRITERIA FOR MITRAL VALVULOPLASTY • SIGNIFICANT SYMPTOMS • ISLOTED MITRAL STENOSIS • NO (OR TRIVIAL) MITRAL REGURGITATION • MOBILE,NON CALCIFIED VALVE ON ECHO • LA FREE OF THROMBUS