Microarrays analyze gene expression in cells to compare the genes expressed in diseased versus healthy cells. This helps scientists better understand diseases like cancer, allowing doctors to create personalized treatment plans. While microarrays provide extensive genetic data analysis and applications, their use requires intensive labor and expensive equipment. They also produce large amounts of data that can be challenging for scientists to interpret.
Biology Molecular
University of Haifa. (2015, August 13). Big data and the social character of genes. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150813084035.htm
Lawrence Berkeley National Laboratory. (2015, August 4). Keeping algae from stressing out. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150804144013.htm
Martínez Sánchez, Lina María. Biología Molecular. 8.ed. Medellín. UPB. Facultad de Medicina.
Biology Molecular
University of Haifa. (2015, August 13). Big data and the social character of genes. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150813084035.htm
Lawrence Berkeley National Laboratory. (2015, August 4). Keeping algae from stressing out. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150804144013.htm
Martínez Sánchez, Lina María. Biología Molecular. 8.ed. Medellín. UPB. Facultad de Medicina.
SOJ Genetic Science (SOJGS) is an Open Access Publication which aims to reveal the intriguing secrets encoded in the genetic codons. SOGS is a Scientific Journal that has dedicated itself for promoting genetic research and facilitating the application of this research in the fight against diseases. The deadliest of diseases like cancer and HIV can also be effectively managed by controlling the genetic pathways for these diseases.
SOJGS encompasses genomic constitution, gene expression & regulation, heredity, genetic variation, gene mutations and genomic evolution etc. in all life forms (plants, animals and microcellular organisms). The scope of the journal covers cell reproduction, protein synthesis, metabolic molecular pathways, immune mechanisms, disease transmission and molecular origin of diseases.
Disease monitoring in wheat through remotely sensed dataCIMMYT
Remote sensing –Beyond images
Mexico 14-15 December 2013
The workshop was organized by CIMMYT Global Conservation Agriculture Program (GCAP) and funded by the Bill & Melinda Gates Foundation (BMGF), the Mexican Secretariat of Agriculture, Livestock, Rural Development, Fisheries and Food (SAGARPA), the International Maize and Wheat Improvement Center (CIMMYT), CGIAR Research Program on Maize, the Cereal System Initiative for South Asia (CSISA) and the Sustainable Modernization of the Traditional Agriculture (MasAgro)
Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infectio...ExternalEvents
http://www.fao.org/about/meetings/wgs-on-food-safety-management/en/
Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infection Control in an Institutional Setting. Presentation from the Technical Meeting on the impact of Whole Genome Sequencing (WGS) on food safety management and GMI-9, 23-25 May 2016, Rome, Italy.
SOJ Genetic Science (SOJGS) is an Open Access Publication which aims to reveal the intriguing secrets encoded in the genetic codons. SOGS is a Scientific Journal that has dedicated itself for promoting genetic research and facilitating the application of this research in the fight against diseases. The deadliest of diseases like cancer and HIV can also be effectively managed by controlling the genetic pathways for these diseases.
SOJGS encompasses genomic constitution, gene expression & regulation, heredity, genetic variation, gene mutations and genomic evolution etc. in all life forms (plants, animals and microcellular organisms). The scope of the journal covers cell reproduction, protein synthesis, metabolic molecular pathways, immune mechanisms, disease transmission and molecular origin of diseases.
Disease monitoring in wheat through remotely sensed dataCIMMYT
Remote sensing –Beyond images
Mexico 14-15 December 2013
The workshop was organized by CIMMYT Global Conservation Agriculture Program (GCAP) and funded by the Bill & Melinda Gates Foundation (BMGF), the Mexican Secretariat of Agriculture, Livestock, Rural Development, Fisheries and Food (SAGARPA), the International Maize and Wheat Improvement Center (CIMMYT), CGIAR Research Program on Maize, the Cereal System Initiative for South Asia (CSISA) and the Sustainable Modernization of the Traditional Agriculture (MasAgro)
Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infectio...ExternalEvents
http://www.fao.org/about/meetings/wgs-on-food-safety-management/en/
Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infection Control in an Institutional Setting. Presentation from the Technical Meeting on the impact of Whole Genome Sequencing (WGS) on food safety management and GMI-9, 23-25 May 2016, Rome, Italy.
All the latest talent acquisition tools. One platform. Ascendify’s Talent Cloud Platform is a completely mobile, social, talent acquisition platform – combining all the modern point solutions into one. For candidates, we transform your career site into a talent community. And for your hiring teams, we provide a suite of applications– CRM, Referrals, Nurturing, and Analytics – plus, it’s all optimized for mobile thanks to Responsive Design technology.
Manuela Echavarría Noreña
Medicine student
UPB
Molecular Biology
"Viruses in genome important for our brain." and "Study finds new target for controlling cell division."
Application of Microarray Technology and softcomputing in cancer BiologyCSCJournals
DNA microarray technology has emerged as a boon to the scientific community in understanding the growth and development of life as well as in widening their knowledge in exploring the genetic causes of anomalies occurring in the working of the human body. microarray technology makes biologists be capable of monitoring expression of thousands of genes in a single experiment on a small chip. Extracting useful knowledge and info from these microarray has attracted the attention of many biologists and computer scientists. Knowledge engineering has revolutionalized the way in which the medical data is being looked at. Soft computing is a branch of computer science capable of analyzing complex medical data. Advances in the area of microarray –based expression analysis have led to the promise of cancer diagnosis using new molecular based approaches. Many studies and methodologies have come up which analyszes the gene espression data by using the techniques in data mining such as feature selection, classification, clustering etc. emboiding the soft computing methods for more accuracy. This review is an attempt to look at the recent advances in cancer research with DNA microarray technology , data mining and soft computing techniques.
This presentation was given to me during my higher education in the Lebanese University, Faculty of Education. It includes detailed explanation about DNA microarray.
Personalized Medicine: Are we there yet?Reid Robison
Slides on the future of healthcare, entitled "Personalized Medicine: Are we there yet?" form a lecture given by Reid Robison, MD MBA at Brigham Young University in the College of Life Sciences in December 2014. The presentation covers the arrival of genome-guided precision medicine as well as the digital health movement and the shift towards a patient-centric, consumer-driven healthcare system.
I will show some news that are important to the understanding of the importance of the genetic transcription and how it provides important tools to the actual medicine
A potential vision of the future "the ncecessary", developed for a presentation at to be provocative. The goal was to think about the near and far future and put it into context with some of the science happening now as well as disruptive steps happening in rare disease science funding. Several slides highlight 'the ideal situation'.
A microarray is a laboratory tool used to detect the expression of thousands of genes at the same time. DNA microarrays are microscope slides that are printed with thousands of tiny spots in defined positions, with each spot containing a known DNA sequence or gene.
Recently, it was reported that the forkhead box O (FoxO) transcription factor promotes human cytomegalovirus (HCMV)
replication via direct binding to the promoters of the major immediate-early (MIE) genes, but how the FoxO factor impacts HCMV
replication remains unknown. In this report, we found that human cytomegalovirus (HCMV), a beta herpesvirus member, could
dramatically induce the expression of FOXOs in the infected human fibroblasts. The induced FOXOs were recruited into the viral
replication compartments (vRC) in the nucleus, especially at the late stage of infection. Suppression of FOXO expression by RNA
interference significantly inhibited HCMV replication, and the production of progeny virus was reduced remarkably.
Mechanistically, FOXO knockdown intensively crippled viral late gene expression at the transcriptional level, while it only
marginally affected viral DNA synthesis. This study highlights how FoxO enhances HCMV gene transcription and viral replication
to promote productive infection
Accelerate your Kubernetes clusters with Varnish CachingThijs Feryn
A presentation about the usage and availability of Varnish on Kubernetes. This talk explores the capabilities of Varnish caching and shows how to use the Varnish Helm chart to deploy it to Kubernetes.
This presentation was delivered at K8SUG Singapore. See https://feryn.eu/presentations/accelerate-your-kubernetes-clusters-with-varnish-caching-k8sug-singapore-28-2024 for more details.
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
Connector Corner: Automate dynamic content and events by pushing a buttonDianaGray10
Here is something new! In our next Connector Corner webinar, we will demonstrate how you can use a single workflow to:
Create a campaign using Mailchimp with merge tags/fields
Send an interactive Slack channel message (using buttons)
Have the message received by managers and peers along with a test email for review
But there’s more:
In a second workflow supporting the same use case, you’ll see:
Your campaign sent to target colleagues for approval
If the “Approve” button is clicked, a Jira/Zendesk ticket is created for the marketing design team
But—if the “Reject” button is pushed, colleagues will be alerted via Slack message
Join us to learn more about this new, human-in-the-loop capability, brought to you by Integration Service connectors.
And...
Speakers:
Akshay Agnihotri, Product Manager
Charlie Greenberg, Host
GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using Deplo...James Anderson
Effective Application Security in Software Delivery lifecycle using Deployment Firewall and DBOM
The modern software delivery process (or the CI/CD process) includes many tools, distributed teams, open-source code, and cloud platforms. Constant focus on speed to release software to market, along with the traditional slow and manual security checks has caused gaps in continuous security as an important piece in the software supply chain. Today organizations feel more susceptible to external and internal cyber threats due to the vast attack surface in their applications supply chain and the lack of end-to-end governance and risk management.
The software team must secure its software delivery process to avoid vulnerability and security breaches. This needs to be achieved with existing tool chains and without extensive rework of the delivery processes. This talk will present strategies and techniques for providing visibility into the true risk of the existing vulnerabilities, preventing the introduction of security issues in the software, resolving vulnerabilities in production environments quickly, and capturing the deployment bill of materials (DBOM).
Speakers:
Bob Boule
Robert Boule is a technology enthusiast with PASSION for technology and making things work along with a knack for helping others understand how things work. He comes with around 20 years of solution engineering experience in application security, software continuous delivery, and SaaS platforms. He is known for his dynamic presentations in CI/CD and application security integrated in software delivery lifecycle.
Gopinath Rebala
Gopinath Rebala is the CTO of OpsMx, where he has overall responsibility for the machine learning and data processing architectures for Secure Software Delivery. Gopi also has a strong connection with our customers, leading design and architecture for strategic implementations. Gopi is a frequent speaker and well-known leader in continuous delivery and integrating security into software delivery.
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
Neuro-symbolic is not enough, we need neuro-*semantic*Frank van Harmelen
Neuro-symbolic (NeSy) AI is on the rise. However, simply machine learning on just any symbolic structure is not sufficient to really harvest the gains of NeSy. These will only be gained when the symbolic structures have an actual semantics. I give an operational definition of semantics as “predictable inference”.
All of this illustrated with link prediction over knowledge graphs, but the argument is general.
Search and Society: Reimagining Information Access for Radical FuturesBhaskar Mitra
The field of Information retrieval (IR) is currently undergoing a transformative shift, at least partly due to the emerging applications of generative AI to information access. In this talk, we will deliberate on the sociotechnical implications of generative AI for information access. We will argue that there is both a critical necessity and an exciting opportunity for the IR community to re-center our research agendas on societal needs while dismantling the artificial separation between the work on fairness, accountability, transparency, and ethics in IR and the rest of IR research. Instead of adopting a reactionary strategy of trying to mitigate potential social harms from emerging technologies, the community should aim to proactively set the research agenda for the kinds of systems we should build inspired by diverse explicitly stated sociotechnical imaginaries. The sociotechnical imaginaries that underpin the design and development of information access technologies needs to be explicitly articulated, and we need to develop theories of change in context of these diverse perspectives. Our guiding future imaginaries must be informed by other academic fields, such as democratic theory and critical theory, and should be co-developed with social science scholars, legal scholars, civil rights and social justice activists, and artists, among others.
GraphRAG is All You need? LLM & Knowledge GraphGuy Korland
Guy Korland, CEO and Co-founder of FalkorDB, will review two articles on the integration of language models with knowledge graphs.
1. Unifying Large Language Models and Knowledge Graphs: A Roadmap.
https://arxiv.org/abs/2306.08302
2. Microsoft Research's GraphRAG paper and a review paper on various uses of knowledge graphs:
https://www.microsoft.com/en-us/research/blog/graphrag-unlocking-llm-discovery-on-narrative-private-data/
Transcript: Selling digital books in 2024: Insights from industry leaders - T...BookNet Canada
The publishing industry has been selling digital audiobooks and ebooks for over a decade and has found its groove. What’s changed? What has stayed the same? Where do we go from here? Join a group of leading sales peers from across the industry for a conversation about the lessons learned since the popularization of digital books, best practices, digital book supply chain management, and more.
Link to video recording: https://bnctechforum.ca/sessions/selling-digital-books-in-2024-insights-from-industry-leaders/
Presented by BookNet Canada on May 28, 2024, with support from the Department of Canadian Heritage.
State of ICS and IoT Cyber Threat Landscape Report 2024 previewPrayukth K V
The IoT and OT threat landscape report has been prepared by the Threat Research Team at Sectrio using data from Sectrio, cyber threat intelligence farming facilities spread across over 85 cities around the world. In addition, Sectrio also runs AI-based advanced threat and payload engagement facilities that serve as sinks to attract and engage sophisticated threat actors, and newer malware including new variants and latent threats that are at an earlier stage of development.
The latest edition of the OT/ICS and IoT security Threat Landscape Report 2024 also covers:
State of global ICS asset and network exposure
Sectoral targets and attacks as well as the cost of ransom
Global APT activity, AI usage, actor and tactic profiles, and implications
Rise in volumes of AI-powered cyberattacks
Major cyber events in 2024
Malware and malicious payload trends
Cyberattack types and targets
Vulnerability exploit attempts on CVEs
Attacks on counties – USA
Expansion of bot farms – how, where, and why
In-depth analysis of the cyber threat landscape across North America, South America, Europe, APAC, and the Middle East
Why are attacks on smart factories rising?
Cyber risk predictions
Axis of attacks – Europe
Systemic attacks in the Middle East
Download the full report from here:
https://sectrio.com/resources/ot-threat-landscape-reports/sectrio-releases-ot-ics-and-iot-security-threat-landscape-report-2024/
DevOps and Testing slides at DASA ConnectKari Kakkonen
My and Rik Marselis slides at 30.5.2024 DASA Connect conference. We discuss about what is testing, then what is agile testing and finally what is Testing in DevOps. Finally we had lovely workshop with the participants trying to find out different ways to think about quality and testing in different parts of the DevOps infinity loop.
Slack (or Teams) Automation for Bonterra Impact Management (fka Social Soluti...Jeffrey Haguewood
Sidekick Solutions uses Bonterra Impact Management (fka Social Solutions Apricot) and automation solutions to integrate data for business workflows.
We believe integration and automation are essential to user experience and the promise of efficient work through technology. Automation is the critical ingredient to realizing that full vision. We develop integration products and services for Bonterra Case Management software to support the deployment of automations for a variety of use cases.
This video focuses on the notifications, alerts, and approval requests using Slack for Bonterra Impact Management. The solutions covered in this webinar can also be deployed for Microsoft Teams.
Interested in deploying notification automations for Bonterra Impact Management? Contact us at sales@sidekicksolutionsllc.com to discuss next steps.
2. * Microarrays analyze cells to determine if
certain genes are being expressed or not
expressed.
* With being able to tell if certain genes are
being expressed, scientists are able to compare
the genes expressed in a diseased cell, to the
genes expressed in a normal healthy cell to be
able to see which genes that are expressed in a
diseased cell and not in a healthy cell
*
3. * Cancer is one of the big diseases microarrays
have been used to help better understand and
treat.
* With microarrays doctors are even able to
create a specific treatment plan for each
patient.
* With microarrays doctors are even able to test
for an elevated expression of a certain gene
which can help in predicting cancer outcomes
and in assigning appropriate treatment.
*
4. * The behavior of many genes can be
simultaneously studied
* Very fast. So fast that as many as 150 copies of
an array of 12,000 genes can be printed in a
day
*
5. * Intensive labor is required to prepare for the
whole microarray process
* To initially open a facility dedicated to
microarray technology is expensive, along with
buying the machinery required
* Almost too much data for scientists to be able
to analyze is produced
*
6. * Microarrays provide extensive range of the
application of genetic diagnosis which can lead
to genetic discrimination
* Microarrays can also be used in prenatal testing
from a chorionic sample and this sample can
tell the mother if the child will be more adept
to have certain diseases, but could also be
used to tell if the child had certain ‘desirable’
traits
*
7. * With microarrays, its possible to analyze tens
of thousands of genes at one time which would
generate lots of data. This data could be used
to identify the fingerprints of gene expression
which could then be used to categorize certain
diseases.
8. * With microarray techniques, there’s the
possibility of being able to create a genetic
profile for everyone and this profile could tell
things like a person’s risk for disease, the
affect of certain drugs or antibiotics, the side
affects of certain drugs or antibiotics, and
maybe even personality traits
*