This document provides an overview of the history and cultures of ancient Mesoamerican civilizations including the Olmecs, Zapotecs, Nazca, Moche, Maya, Toltecs, and Aztecs. It describes the origins and migrations of early peoples in North and South America, the emergence of advanced agricultural practices and urban settlements in Mesoamerica, and highlights key aspects of culture, religion, and society for each civilization. The document also summarizes the rise and fall of the powerful Aztec Empire and their defeat by the Spanish conquistador Hernan Cortes in 1521.