Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
What are the causes of sinus bradycardia? (DU-04Ja)
Sinus bradycardia is a condition where the sinus node in the heart beats slower than the normal range of 60-100 beats per minute. Some common causes of sinus bradycardia include:
Vagal stimulation: This occurs due to an increased activity of the vagus nerve, which is responsible for slowing down the heart rate.
Medications: Certain medications like beta-blockers, calcium channel blockers, and digoxin can cause sinus bradycardia.
Hypothyroidism: Inadequate production of thyroid hormones can cause a decrease in metabolic rate and lead to bradycardia.
Increased intracranial pressure: High pressure within the skull due to conditions like head injury, brain tumors or bleeding can affect the autonomic nervous system and cause bradycardia.
Obstructive sleep apnea: Repeated episodes of apnea during sleep can cause bradycardia due to decreased oxygen supply to the body.
Aging: As the body ages, the electrical activity of the heart can slow down, leading to sinus bradycardia.
Other causes of sinus bradycardia include viral infections, genetic disorders, and certain electrolyte imbalances.
2. A 25 years old female presented with palpitation, on examination her pulse was irregularly irregular. How will you assess and investigate her? (DU- 05Ja)
The patient's presentation suggests the possibility of atrial fibrillation, which is a common arrhythmia characterized by an irregularly irregular pulse. The following are the steps that can be taken to assess and investigate the patient:
History taking: Obtain a detailed history of the patient's symptoms, including the onset, duration, and frequency of palpitations, associated symptoms, and any relevant medical history.
Physical examination: Conduct a thorough physical examination, including a cardiovascular examination, to assess the patient's heart sounds, rhythm, and rate. Check for any signs of heart failure or underlying heart disease.
Electrocardiogram (ECG): Perform an ECG to confirm the diagnosis of atrial fibrillation and to determine the heart rate and rhythm. An ECG will also help rule out other arrhythmias or underlying heart conditions.
Blood tests: Check the patient's thyroid function, electrolyte levels, and other relevant blood tests to identify any underlying conditions that may be causing the arrhythmia.
Echocardiography: Perform an echocardiogram to assess the structure and function of the heart and to identify any underlying heart disease.
Holter monitor: Use a Holter monitor to monitor the patient's heart rate and rhythm over a 24-hour period to identify any episodes of atrial fibrillation that may not be captured during a routine ECG.
Other tests: Consider other tests, such as a stress test or electrophysiology study, if necessary, to further evaluate the patient's heart funct
Myocardial infarction is the medical name of a heart attack. A heart attack is a life-threatening condition that occurs when blood flow to the heart muscle is abruptly cut off, causing tissue damage. This is usually the result of a blockage in one or more of the coronary arteries.Symptoms include tightness or pain in the chest, neck, back or arms, as well as fatigue, lightheadedness, abnormal heartbeat and anxiety. Women are more likely to have atypical symptoms than men.
Treatment ranges from lifestyle changes and cardiac rehabilitation to medication, stents, and bypass surgery.
Myocardial infarction is the medical name of a heart attack. A heart attack is a life-threatening condition that occurs when blood flow to the heart muscle is abruptly cut off, causing tissue damage. This is usually the result of a blockage in one or more of the coronary arteries.Symptoms include tightness or pain in the chest, neck, back or arms, as well as fatigue, lightheadedness, abnormal heartbeat and anxiety. Women are more likely to have atypical symptoms than men.
Treatment ranges from lifestyle changes and cardiac rehabilitation to medication, stents, and bypass surgery.
A blockage of blood flow to the heart muscle.
A heart attack is a medical emergency. A heart attack usually occurs when a blood clot blocks blood flow to the heart. Without blood, tissue loses oxygen and dies.
Symptoms include tightness or pain in the chest, neck, back or arms, as well as fatigue, lightheadedness, abnormal heartbeat and anxiety. Women are more likely to have atypical symptoms than men.
Treatment ranges from lifestyle changes and cardiac rehabilitation to medication, stents and bypass surgery.
Periodontal Treatment of Medically Compromised Patients [Autosaved].pptxANIL KUMAR
The world's population is estimated to be over 7.7 billion. [1] Within this mass of humanity is a
substantial number of people who are elderly; the graying of the world's population is predicted to
produce millions of individuals with systemic medical conditions that can affect oral health and
dental treatment. The dental management of these medically compromised patients can be
problematic in terms of oral complications, dental therapy, and emergency care
refers to several diseases other than athersclerosis, which causes a narrowing of major epicardial coronary arteries.
it is also knownas ischemic hert disease.
Pulmonary hypertension (PH) is a complex and progressive
condition characterised by high blood pressure in the lungs, leading
to significant health challenges. This book is dedicated to unravelling
the intricacies of PH, encompassing its pathophysiology, diagnosis,
management and emerging research trends. It is designed to serve
as a comprehensive guide for clinicians, researchers and students
in the field of cardiology and respiratory medicine, as well as a
valuable resource for patients and their families seeking to deepen
their understanding of this condition.
The chapters of this book are structured to provide a detailed
insight into the various facets of PH. Starting with the basic
pathophysiology and classification systems, I delve into the
clinical presentation, diagnostic criteria and the nuances of
managing this condition, including both pharmacological and
non-pharmacological approaches. Special attention is given to
the unique challenges posed by pediatric PH, PH in pregnancy
and the management of co-morbidities and complications.
Recognizing the rapid advancements in the field, this book also
dedicates a significant portion to discussing current research
trends, future therapeutic targets and evolving diagnostic
techniques. Real-world case studies and patient testimonies are
included to provide a practical perspective, highlighting the
impact of PH on patients’ lives and the importance of a patient-
centered approach to care.
The field of pulmonary hypertension is one of dynamic change
and I growing understanding. Through this book, we aim to
provide a thorough and up-to-date resource that reflects the
current state of knowledge and practice in the field of PH, while
also offering a glimpse into the future directions of research and
treatment. It is my hope that this book will not only enhance the
understanding of PH among healthcare professionals but also offer
support and information to patients and their families navigating
this challenging condition.
A blockage of blood flow to the heart muscle.
A heart attack is a medical emergency. A heart attack usually occurs when a blood clot blocks blood flow to the heart. Without blood, tissue loses oxygen and dies.
Symptoms include tightness or pain in the chest, neck, back or arms, as well as fatigue, lightheadedness, abnormal heartbeat and anxiety. Women are more likely to have atypical symptoms than men.
Treatment ranges from lifestyle changes and cardiac rehabilitation to medication, stents and bypass surgery.
Periodontal Treatment of Medically Compromised Patients [Autosaved].pptxANIL KUMAR
The world's population is estimated to be over 7.7 billion. [1] Within this mass of humanity is a
substantial number of people who are elderly; the graying of the world's population is predicted to
produce millions of individuals with systemic medical conditions that can affect oral health and
dental treatment. The dental management of these medically compromised patients can be
problematic in terms of oral complications, dental therapy, and emergency care
refers to several diseases other than athersclerosis, which causes a narrowing of major epicardial coronary arteries.
it is also knownas ischemic hert disease.
Pulmonary hypertension (PH) is a complex and progressive
condition characterised by high blood pressure in the lungs, leading
to significant health challenges. This book is dedicated to unravelling
the intricacies of PH, encompassing its pathophysiology, diagnosis,
management and emerging research trends. It is designed to serve
as a comprehensive guide for clinicians, researchers and students
in the field of cardiology and respiratory medicine, as well as a
valuable resource for patients and their families seeking to deepen
their understanding of this condition.
The chapters of this book are structured to provide a detailed
insight into the various facets of PH. Starting with the basic
pathophysiology and classification systems, I delve into the
clinical presentation, diagnostic criteria and the nuances of
managing this condition, including both pharmacological and
non-pharmacological approaches. Special attention is given to
the unique challenges posed by pediatric PH, PH in pregnancy
and the management of co-morbidities and complications.
Recognizing the rapid advancements in the field, this book also
dedicates a significant portion to discussing current research
trends, future therapeutic targets and evolving diagnostic
techniques. Real-world case studies and patient testimonies are
included to provide a practical perspective, highlighting the
impact of PH on patients’ lives and the importance of a patient-
centered approach to care.
The field of pulmonary hypertension is one of dynamic change
and I growing understanding. Through this book, we aim to
provide a thorough and up-to-date resource that reflects the
current state of knowledge and practice in the field of PH, while
also offering a glimpse into the future directions of research and
treatment. It is my hope that this book will not only enhance the
understanding of PH among healthcare professionals but also offer
support and information to patients and their families navigating
this challenging condition.
I wish to express our heartfelt gratitude to the following
individuals whose unwavering support and contributions have
played a pivotal role in the creation of this book "Innovations in
Cardiology: From Fundamentals to Frontiers – Short Notes in
Cardiology," My sincere thanks go to: Professor Sufia Rahman,
Professor Abdullah Al Shafi Majumder, Professor dr. Abduz
Zaher, Professor Syed Azizul Haque, Professor Dr Nurunnahar
Fatema Begum; Professor Md. Atahar Ali, Professor Dr. Afzalur
Rahman, Professor Fazila- Tun- Nessa Malik, Professor Kh.
Qamrul Islam; Professor Dr. GM Faruque, Professor M.
Maksumul Haq,Professo Dr. Sajal Krisna Banerjee; Professor
Dr. STM Abu Azam; Professor Mir Jamal Uddin, Professor
Mohammad Abdur Rashid, Professor Dr. AKM Fazlur Rahman,
Professor Dr. Abdul Kader Akanda, Professor Dr. AQM Reza,
Professor Dr. Saiful Islam; Dr. Shams Munwar; Professor Dr.
Chaudhury Meshkat Ahmed, Professor Dr. Khaled Mohsin,
Professor Abdul Wadud Chowdhury, Professor Razia Sultana
Mahmud,Professor Dr. M Touhidul Haque; Professor Dr. Md.
Sahabuddin, Professor Prabir Kumar Das, Professor Dr. Baren
Chakraborty, Professor Dr. Amirul Khusru, Dr. Kaiser Nasrullah
Khan, Professor Ashok Dutta, Professor Md. Khalequzzaman,
Dr. Abdullah Al Jamil, Professor Dr. Amal Kumar Choudhury,
Professor Mostafa Zaman Babul, Professor Dr Dipal Krishna
Adhikary, Professor Dr. Dipankar Chandra Nag professor Dr.
Moeen Uddin Ahmed, professor Mir nesar Uddin; Brig. Gen. Dr.
Syeda Aleya Sultana,Professor Dr Syed Nasir Uddin; Professor
Dr Mohsin Hossain; Dr. Sm Shahidul Haque; Professor Dr
Tawfiq Shahriar Huq; Dr. SM Quamrul Haque; Professor Dr.
Mamunur Rashid Sizar, Professor Dr. Mohsin Ahmed, Professor
Dr. Zillur Rahman; Professor Dr. Tanjima Parveen; Professor Dr.
Harisul hoque, Dr. Reyan Anis, Dr. Ashish Dey, Dr. Mohammad
Ullah firoz, Professor Dr. Udoy Shankar Roy; Dr. Nuruddin
Tareq; Dr. Md. Towhiduzzaman, Dr. Kh. Asaduzzaman, Dr.
AKM Monwarul Islam, Dr. Abdul Momen, Dr. Md. Shafiqur
Rahman Patwary, Dr. Md, Zulfiker Ali Lenin; Dr. Mahbub
Mansur, Dr. CM Shaheen Kabir, Dr. Rumi Alam, Dr. Farah
ii
Tasneem Mowmi, Dr. Rashid Ahmed, Dr. Mohammad Anowar
Hossain, Dr. Mohammad Nasimul Gani,Professor Dr abu Tarek
Iqbal, Dr. Husnayen Nanna, Dr. Abdul Malek, Dr, Ajoy Kumar
Datta, Dr. Nur Alam; Dr. Sahela Nasrin; Dr. Haripada sarker, Dr.
Anisul Awal, Dr. Shaila Nabi; Professor Dr. Umme Salma Khan;
Dr SM Ahsan Habib; Professor Dr Solaiman Hossain; Dr. Bijoy
Dutta,Dr. Shahana Zaman; Dr. Ishrat Jahan shimu, Dr. Ibrahim
Khalil. Dr. Chayan Kumar Singha, Dr. Kazi Nazrul Islam, Dr.
Kamal pasha; professor Dr. Liakat Hossain Tapan, Professor Dr.
Mamun Iqbal, Professor Dr. MG Azam, Dr. Lima Asrin Sayami,
Dr. Smita Kanungo; Dr. Sadequl Islam Shamol; Dr. Swadesh
chakraborty; Dr. Md. Rasul Amin Shepon; Dr. Saqif shahriar;
Your collective wisdom, expertise and commitment to the field
of cardiology have enriched the content of this book. Your
mentorship and guidance have been invaluable in shapi
Definition: Cardiac arrhythmias refer to abnormal heart rhythms, where the heartbeat may be too slow (bradycardia), too fast (tachycardia), or irregular.
These irregularities disrupt the normal electrical signaling in the heart.
In a world where hearts beat free and bold,
A silent foe creeps, its story untold,
Rheumatic whispers, in hushed refrain,
A tale of love's struggle, of heartache and pain.
A childhood song, innocent and sweet,
Takes a tragic turn, hearts skip a beat,
Rheumatic winds blow, fierce and unseen,
Leaving scars on hearts that once danced so keen.
Valves that should open, a rhythmic embrace,
Now bear the weight of this silent chase,
Rheumatic echoes, a haunting refrain,
Leaving imprints of sorrow, of loss and of pain.
But amidst the shadows, there's hope that glows,
A symphony of care, compassion bestows,
With knowledge and love, we stand side by side,
To mend these hearts, to be a healing guide.
Rheumatic battles, we'll face them anew,
A united front, a relentless crew,
For every heart deserves freedom's embrace,
And in the face of rheumatic storms, we'll find grace.
So let's raise our voices, let the world hear,
The fight against rheumatic pain, we hold dear,
With courage and faith, we'll rewrite the verse,
A tale of triumph, of hearts that converse.
"Rheumatic fever reminds us that our body is a delicate symphony, and neglecting even the slightest discord can lead to profound consequences." -
"In the battle against rheumatic fever, awareness and early intervention are our most potent allies."
"Rheumatic fever teaches us the vital lesson that the heart, both physical and emotional, must be nurtured with care and vigilance." -
"Every case of rheumatic fever avoided is a triumph of knowledge, compassion, and the will to protect our most vital instrument, the heart." -
"Rheumatic fever serves as a reminder that even the strongest fortresses need vigilant guardians to shield against the unseen enemies within." -
Case Scenario: You're presenting research findings on hypertension prevalence in
different regions. What Excel chart type would best visualize the variation in
prevalence across regions?
Options: A) Line chart B) Pie chart C) Bar chart D) Scatter plot E) Radar chart Answer:
C) Bar chart
Explanation: A bar chart effectively compares values across different categories,
making it ideal for visualizing the variation in hypertension prevalence across different
regions.
Case Scenario: You're analyzing patient demographics, and you want to find the
most common blood type among your patients. What Excel function would help
you identify the mode of the blood types?
Options: A) MEDIAN B) MODE C) COUNTIF D) AVERAGE E) SUM Answer: B)
MODE
Explanation: The MODE function in Excel helps you find the most frequently occurring
value in a range, making it suitable for identifying the most common blood type among
patients.
Case Scenario: You're conducting a study on the effects of exercise on blood
pressure. What Excel tool would you use to create a summary table showing
average blood pressure before and after exercise?
Options: A) Goal Seek B) PivotTable C) Data Validation D) Filter E) Sort Answer: B)
PivotTable
Explanation: A PivotTable in Excel can summarize data and calculate averages,
making it suitable for creating a summary table showing average blood pressure before
and after exercise.
Case Scenario: You're managing patient records and need to categorize patients
into age groups for analysis. What Excel function would you use to assign each
patient to a specific age category?
Options: A) VLOOKUP B) IF C) COUNTIF D) INDEX E) MATCH Answer: B)
IF
Explanation: The IF function in Excel allows you to apply conditional logic. It's useful
for categorizing patients into age groups based on their ages.
Case Scenario: You're analyzing the effectiveness of a new drug on reducing
cholesterol levels in patients. Which Excel function would you use to calculate
the percentage reduction in cholesterol for each patient?
Options: A) SUMIF B) AVERAGEIF C) MEDIAN D) COUNTIF E) IF Answer: E) IF
Explanation: The IF function in Excel allows you to apply conditional logic. It's useful
for calculating the percentage reduction in cholesterol levels based on the original and
post-treatment values.
Case Scenario: You're preparing a presentation on global prevalence rates of
different heart diseases. What Excel chart type would best display the proportion
of each disease in relation to the whole?
Options: A) Line chart B) Scatter plot C) Bar chart D) Pie chart E) Area chart Answer:
D) Pie chart
Explanation: A pie chart effectively displays proportions and percentages, making it
ideal for showcasing the proportion of each heart disease in relation to the total.
Case Scenario: You're managing a database of medical research papers, including
titles, authors, and publication years. What Excel tool can you use to quickly find
papers published between cert
5. A 5 years old boy presents with fever & swelling of knee and ankle joint for 3 weeks. Write down 3 important D/D. Discuss the treatment of acute rheumatic fever with carditis. (DU-09Ju)
Three important differential diagnoses of a 5-year-old boy presenting with fever and joint swelling for 3 weeks include:
Septic arthritis: This is an acute bacterial infection of a joint that causes similar symptoms to rheumatic fever but is usually monoarticular and associated with more severe pain, redness, and tenderness of the affected joint. Septic arthritis requires urgent drainage and antibiotics.
Juvenile idiopathic arthritis: This is a group of chronic autoimmune disorders that can present with fever, joint swelling, and stiffness. The diagnosis is based on clinical features, laboratory tests, and imaging studies. The treatment may include nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs, and biologic agents.
Reactive arthritis: This is an inflammatory joint disease that can occur after an infection, especially with certain bacteria such as Chlamydia, Salmonella, or Shigella. Reactive arthritis usually affects the lower limb joints, such as knees, ankles, and feet, and may be associated with skin rash, eye inflammation, or urethritis. The treatment may include antibiotics, nonsteroidal anti-inflammatory drugs, and corticosteroids.
Assuming the diagnosis of acute rheumatic fever with carditis, the treatment usually involves a combination of antibiotics and anti-inflammatory drugs. The antibiotics aim to eradicate the streptococcal infection and prevent further rheumatic fever recurrences, while the anti-inflammatory drugs aim to reduce the inflammation and symptoms of carditis. The specific regimen may vary depending on the severity of carditis, the presence of other complications, and the patient's age and weight. In general, the following principles apply:
Antibiotics: A 10-day course of oral or intramuscular penicillin is the first-line antibiotic for acute rheumatic fever, as it is effective against most strains of streptococci and has low toxicity. Alternative antibiotics may be used for patients who are allergic to penicillin or have recurrent rheumatic fever despite adequate penicillin therapy. Long-term prophylaxis with penicillin is recommended to prevent recurrences, usually until the age of 21 years or for 10 years after the last episode of rheumatic fever, whichever is longer.
Anti-inflammatory drugs: High-dose aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen are usually given for the first 2-3 weeks of acute rheumatic fever to control fever, pain, and inflammation. Corticosteroids such as prednisone or methylprednisolone may be used in severe cases of carditis or when other therapies are not effective or contraindicated. The duration and dose of anti-inflammatory drugs should be tailored to the patient's response and adverse effects, such as gastric
The Cardiovascular System: Life's Vital Transport System
The cardiovascular system, comprising the heart, blood vessels, and blood, is a fundamental physiological network in the body.
It facilitates the circulation of oxygen, nutrients, hormones, and immune cells while eliminating waste products.
Essential for maintaining tissue function, energy production, and overall homeostasis.
Defining the Cardiovascular System
The cardiovascular system, also known as the circulatory system, is a complex network responsible for circulating vital substances throughout the body.
Components of the Cardiovascular System
Heart: A muscular organ that pumps blood, generating the force required to propel blood through the blood vessels.
Blood Vessels: A network of tubes that carry blood to and from various body tissues.
Blood: A specialized fluid containing red and white blood cells, platelets, and plasma, essential for nutrient and gas exchange.
Exploring Applied Physiology of the Cardiovascular System
The cardiovascular system is a cornerstone of human health, regulating the circulation of vital nutrients, oxygen, and waste products throughout the body.
Understanding the applied physiology of this system is essential for healthcare professionals to provide effective medical care and interventions.
Importance of Applied Cardiovascular Physiology
Effective healthcare requires a deep comprehension of how the cardiovascular system functions under various conditions.
Applied physiology knowledge empowers healthcare practitioners to make informed decisions, diagnose disorders, and formulate targeted treatment plans.
Focus on Practical Applications in Healthcare
This presentation delves into the practical aspects of cardiovascular physiology that directly impact clinical practice.
We will explore how physiological concepts are translated into real-world medical scenarios and interventions.
By grasping the applied physiology of the cardiovascular system, healthcare providers can optimize patient care, enhance diagnostics, and improve treatment outcomes.
Throughout this presentation, we'll bridge the gap between theoretical understanding and its practical implications in the field of healthcare.
Understanding the Components
The cardiovascular system comprises three crucial components: the heart, blood vessels, and blood.
Heart: A muscular organ that pumps blood, ensuring a continuous flow throughout the body.
Blood Vessels: A network of tubes that transport blood to and from various tissues.
Blood: A specialized fluid that carries nutrients, oxygen, hormones, and removes waste products.
Role in Oxygen and Nutrient Delivery
Oxygen from the lungs and nutrients from the digestive system are transported to body tissues through the bloodstream.
These essential components are required for cellular metabolism and energy production.
Peripartum cardiomyopathy (PPCM) is a type of heart disease that affects women during the last month of pregnancy or in the first few months after delivery. It is characterized by a weakened and enlarged heart muscle, which makes it difficult for the heart to pump blood efficiently to the rest of the body. The exact cause of PPCM is unknown, but it is believed to be related to the hormonal changes and increased demands on the heart that occur during pregnancy. Symptoms of PPCM can include shortness of breath, fatigue, chest pain, swelling in the legs and feet, and palpitations. Treatment for PPCM usually involves medications to improve heart function and supportive care to manage symptoms. In severe cases, advanced treatments such as implantable devices or heart transplantation may be necessary. With early diagnosis and treatment, most women with PPCM can recover completely and go on to lead healthy lives.during pregnancy.
The diagnosis of PPCM is based on clinical symptoms, such as shortness of breath, fatigue, chest pain, and edema, along with imaging studies, such as echocardiography. Treatment for PPCM usually involves medications to improve heart function and supportive care to manage symptoms. These medications can include beta-blockers, ACE inhibitors, diuretics, and inotropic agents. In severe cases, advanced treatments such as mechanical circulatory support or heart transplantation may be necessary.
The prognosis for PPCM varies depending on the severity of the disease and the presence of underlying comorbidities. However, with early diagnosis and appropriate treatment, most women with PPCM can recover completely and go on to lead healthy lives. The recurrence rate of PPCM in subsequent pregnancies is approximately 20%, and women who have had PPCM are advised to avoid future pregnancies or undergo careful monitoring and management during pregnancy.
There are still many unanswered questions about PPCM, including its exact cause, optimal diagnostic and treatment strategies, and long-term outcomes. Further research is needed to better understand this complex and potentially life-threatening condition.
In conclusion, PPCM is a rare but serious form of heart disease that can occur during or after pregnancy. Early recognition and management of this condition are critical in preventing complications and improving outcomes for both the mother and the baby. Future research will continue to shed light on the pathophysiology and optimal management of PPCM.
Cardiac rehabilitation is a comprehensive program that aims to improve the health and quality of life of individuals with cardiovascular disease. This review article provides an overview of current evidence-based practices and the benefits of cardiac rehabilitation. The article discusses the components of cardiac rehabilitation, including medical evaluation, physical activity and exercise training, nutrition counseling and education, psycho social support and counseling, cardiac risk factor management, medication management, and tobacco cessation counseling. The article also discusses the effectiveness of cardiac rehabilitation in reducing mortality rates, improving functional capacity, and reducing the risk of future cardiovascular events. Additionally, the article explores the future directions of cardiac rehabilitation, including personalized medicine, technology integration, home-based programs, expanded target populations, and a multidisciplinary approach. Healthcare providers play a crucial role in encouraging and referring eligible patients to cardiac rehabilitation programs as part of their treatment plan. The review concludes that cardiac rehabilitation is an essential aspect of the management of cardiovascular disease and highlights the need for further research and development in this dynamic field.
Outline of CPR manual
I. Introduction
A. Definition of CPR
1. Explanation of what CPR stands for
2. Definition of CPR as a life-saving technique
B. Importance of CPR
1. Statistics on cardiac arrest and survival rates
2. Explanation of why CPR is crucial for saving lives
C. Objective of the manual
1. Explanation of what readers will learn from the manual
2. Statement of the manual's purpose
II. Getting Started with CPR
A. Assessing the situation
1. Importance of assessing the situation before starting CPR
2. Factors to consider when assessing the situation
B. Checking for responsiveness
1. Explanation of how to check for responsiveness
2. Importance of checking for responsiveness
C. Activating the emergency response system
1. Explanation of when to activate the emergency response system
2. Step-by-step guide to activating the emergency response system
III. Basic Life Support Techniques
A. Key components of basic life support
1. Explanation of the components of basic life support
2. Importance of each component
B. The ABCs of CPR
1. Explanation of the ABCs of CPR
2. Importance of each step in the ABCs of CPR
C. Performing chest compressions
1. Explanation of how to perform chest compressions
2. Importance of proper chest compression technique
D. Delivering rescue breaths
1. Explanation of how to deliver rescue breaths
2. Importance of proper rescue breath technique
E. Utilizing an automated external defibrillator (AED)
1. Explanation of what an AED is and how it works
2. Step-by-step guide to using an AED
F. Administering medications during CPR
1. Explanation of medications used during CPR
2. Dosages and administration guidelines for each medication
IV. Advanced Life Support Techniques
A. Advanced airway management
1. Explanation of advanced airway management techniques
2. Importance of advanced airway management in CPR
B. Advanced monitoring techniques
1. Explanation of advanced monitoring techniques
2. Importance of advanced monitoring in CPR
C. Invasive interventions
1. Explanation of invasive interventions
2. Importance of invasive interventions in CPR
D. Extracorporeal membrane oxygenation (ECMO)
1. Explanation of ECMO
2. Importance of ECMO in CPR
V. Improving Outcomes in CPR
A. Factors influencing CPR outcomes
1. Explanation of factors that influence CPR outcomes
2. Importance of understanding these factors
B. Strategies for improving CPR outcomes
1. Explanation of strategies for improving CPR outcomes
2. Importance of implementing these strategies
C. The role of high-quality CPR in improving outcomes
1. Explanation of what high-quality CPR is
2. Importance of performing high-quality CPR
VI. Special Considerations in CPR
A. CPR in special populations
1. Explanation of special populations that require unique CPR techniques
2. Importance of understanding these unique CPR techniques
B. CPR in special settings
1. Explanation of special settings that require unique CPR techniques
2. Importance of understanding these unique CPR techniques
C.
I. Introduction
A. Brief explanation of World Hypertension Day
B. Importance of addressing hypertension as a global health issue
C. Overview of the objectives of the presentation
II. Understanding Hypertension
A. Definition and classification of hypertension
B. Prevalence and global burden of hypertension
C. Risk factors and causes of hypertension
D. Health implications and complications associated with hypertension
III. World Hypertension Day 2023
A. Background and significance of World Hypertension Day
B. Theme and key messages for World Hypertension Day 2023
C. Activities and events organized worldwide to raise awareness
IV. Goals and Objectives
A. Key goals set for World Hypertension Day 2023
B. Promoting prevention and early detection of hypertension
C. Encouraging healthy lifestyle modifications
D. Enhancing public knowledge about hypertension management
V. Initiatives and Campaigns
A. Overview of global initiatives and campaigns
B. Collaborations with international organizations, NGOs, and healthcare professionals
C. Campaign materials and resources available for public use
VI. Strategies for Hypertension Prevention and Control
A. Implementing population-level interventions
B. Screening and diagnosis strategies
C. Lifestyle modifications (diet, physical activity, stress management)
D. Pharmacological management and treatment guidelines
VII. Public Awareness and Education
A. Importance of raising public awareness about hypertension
B. Educational campaigns and resources for the general public
C. Role of healthcare professionals in educating patients
VIII. Impact and Achievements
A. Highlighting the impact of previous World Hypertension Day campaigns
B. Success stories and achievements in hypertension prevention and control
C. Lessons learned and areas for improvement
IX. Conclusion
A. Recap of the key points discussed
B. Call to action for individuals, communities, and policymakers
C. Encouragement to spread awareness and take steps towards hypertension prevention
. Introduction
A. Definition and prevalence of hypertension in the elderly
B. Importance of managing hypertension in this population
II. Risk Factors and Complications
A. Common risk factors for hypertension in the elderly
B. Potential complications associated with uncontrolled hypertension
III. Diagnostic Process
A. Blood pressure measurement techniques and guidelines
B. Target blood pressure goals for elderly patients
C. Identification of secondary causes of hypertension
IV. Non-Pharmacological Management
A. Lifestyle modifications
1. Dietary recommendations (e.g., DASH diet, sodium reduction)
2. Weight management and physical activity
3. Smoking cessation and alcohol moderation
B. Stress management and relaxation techniques
V. Pharmacological Management
A. First-line antihypertensive medications
B. Considerations for drug selection in the elderly
1. Drug interactions and comorbidities
2. Adverse effects and tolerability
C. Individualized treatment approach based on patient characteristics
VI. Monitoring and Follow-Up
A. Frequency of blood pressure monitoring
B. Importance of medication adherence
C. Adjusting treatment based on patient response
D. Collaborative care and involvement of healthcare professionals
VII. Special Considerations
A. Polypharmacy and medication management
B. Management of hypertension in frail and institutionalized elderly
C. Cognitive impairment and medication adherence
VIII. Controversies and Challenges
A. Blood pressure targets and guidelines in the elderly
B. Conflicting evidence on specific antihypertensive agents
C. Adherence issues and barriers to effective management
IX. Conclusion
A. Summary of key points discussed
B. Importance of comprehensive management in elderly patients
C. Future directions in hypertension management for the elderly
I. Introduction
A. Definition of CPR
1. Explanation of what CPR stands for
2. Definition of CPR as a life-saving technique
B. Importance of CPR
1. Statistics on cardiac arrest and survival rates
2. Explanation of why CPR is crucial for saving lives
C. Objective of the manual
1. Explanation of what readers will learn from the manual
2. Statement of the manual's purpose
II. Getting Started with CPR
A. Assessing the situation
1. Importance of assessing the situation before starting CPR
2. Factors to consider when assessing the situation
B. Checking for responsiveness
1. Explanation of how to check for responsiveness
2. Importance of checking for responsiveness
C. Activating the emergency response system
1. Explanation of when to activate the emergency response system
2. Step-by-step guide to activating the emergency response system
III. Basic Life Support Techniques
A. Key components of basic life support
1. Explanation of the components of basic life support
2. Importance of each component
B. The ABCs of CPR
1. Explanation of the ABCs of CPR
2. Importance of each step in the ABCs of CPR
C. Performing chest compressions
1. Explanation of how to perform chest compressions
2. Importance of proper chest compression technique
D. Delivering rescue breaths
1. Explanation of how to deliver rescue breaths
2. Importance of proper rescue breath technique
E. Utilizing an automated external defibrillator (AED)
1. Explanation of what an AED is and how it works
2. Step-by-step guide to using an AED
F. Administering medications during CPR
1. Explanation of medications used during CPR
2. Dosages and administration guidelines for each medication
IV. Advanced Life Support Techniques
A. Advanced airway management
1. Explanation of advanced airway management techniques
2. Importance of advanced airway management in CPR
B. Advanced monitoring techniques
1. Explanation of advanced monitoring techniques
2. Importance of advanced monitoring in CPR
C. Invasive interventions
1. Explanation of invasive interventions
2. Importance of invasive interventions in CPR
D. Extracorporeal membrane oxygenation (ECMO)
1. Explanation of ECMO
2. Importance of ECMO in CPR
V. Improving Outcomes in CPR
A. Factors influencing CPR outcomes
1. Explanation of factors that influence CPR outcomes
2. Importance of understanding these factors
B. Strategies for improving CPR outcomes
1. Explanation of strategies for improving CPR outcomes
2. Importance of implementing these strategies
C. The role of high-quality CPR in improving outcomes
1. Explanation of what high-quality CPR is
2. Importance of performing high-quality CPR
VI. Special Considerations in CPR
A. CPR in special populations
1. Explanation of special populations that require unique CPR techniques
2. Importance of understanding these unique CPR techniques
B. CPR in special settings
1. Explanation of special settings that require unique CPR techniques
2. Importance of understanding these unique CPR techniques
C. CPR during a pandemic
1
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
MBBS QUESTION ANSWER 3 CARD.pdf
1. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
What are the causes of sinus bradycardia? (DU-04Ja)
Sinus bradycardia is a condition where the sinus node in the heart beats slower than the normal range
of 60-100 beats per minute. Some common causes of sinus bradycardia include:
Vagal stimulation: This occurs due to an increased activity of the vagus nerve, which is
responsible for slowing down the heart rate.
Medications: Certain medications like beta-blockers, calcium channel blockers, and digoxin can
cause sinus bradycardia.
Hypothyroidism: Inadequate production of thyroid hormones can cause a decrease in metabolic
rate and lead to bradycardia.
Increased intracranial pressure: High pressure within the skull due to conditions like head
injury, brain tumors or bleeding can affect the autonomic nervous system and cause bradycardia.
Obstructive sleep apnea: Repeated episodes of apnea during sleep can cause bradycardia due to
decreased oxygen supply to the body.
Aging: As the body ages, the electrical activity of the heart can slow down, leading to sinus
bradycardia.
Other causes of sinus bradycardia include viral infections, genetic disorders, and certain electrolyte
imbalances.
2. A 25 years old female presented with palpitation, on examination
her pulse was irregularly irregular. How will you assess and
investigate her? (DU- 05Ja)
The patient's presentation suggests the possibility of atrial fibrillation, which is a common arrhythmia
characterized by an irregularly irregular pulse. The following are the steps that can be taken to assess
and investigate the patient:
History taking: Obtain a detailed history of the patient's symptoms, including the onset, duration,
and frequency of palpitations, associated symptoms, and any relevant medical history.
Physical examination: Conduct a thorough physical examination, including a cardiovascular
examination, to assess the patient's heart sounds, rhythm, and rate. Check for any signs of heart
failure or underlying heart disease.
2. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Electrocardiogram (ECG): Perform an ECG to confirm the diagnosis of atrial fibrillation and to
determine the heart rate and rhythm. An ECG will also help rule out other arrhythmias or
underlying heart conditions.
Blood tests: Check the patient's thyroid function, electrolyte levels, and other relevant blood tests
to identify any underlying conditions that may be causing the arrhythmia.
Echocardiography: Perform an echocardiogram to assess the structure and function of the heart
and to identify any underlying heart disease.
Holter monitor: Use a Holter monitor to monitor the patient's heart rate and rhythm over a 24-
hour period to identify any episodes of atrial fibrillation that may not be captured during a routine
ECG.
Other tests: Consider other tests, such as a stress test or electrophysiology study, if necessary, to
further evaluate the patient's heart function and arrhythmia.
In summary, the assessment and investigation of a patient with palpitations and an irregularly irregular
pulse would involve a comprehensive evaluation of the patient's symptoms, physical examination, ECG,
blood tests, echocardiogram, and possibly a Holter monitor or other tests to confirm the diagnosis and
identify any underlying conditions.
3. Write short note on : Stokes Adams syndrome. (DU- 06M)
Stokes-Adams syndrome, also known as complete heart block, is a condition characterized by episodes
of syncope (fainting) or seizures due to a sudden and temporary interruption of the heart's electrical
conduction system.
The underlying cause of Stokes-Adams syndrome is often attributed to degeneration or blockage of the
bundle of His, which is a crucial part of the heart's conduction system responsible for transmitting
electrical impulses from the atria to the ventricles. This can lead to a slower heart rate or complete
blockage of the electrical impulses to the ventricles.
Symptoms of Stokes-Adams syndrome can include dizziness, lightheadedness, loss of consciousness,
and seizures. Treatment may involve the use of a pacemaker to regulate the heart's electrical impulses
or medication to manage symptoms. In severe cases, surgical intervention may be required.
3. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
3. Write short note on : Stokes Adams syndrome. (DU- 06M)
Stokes-Adams syndrome is a medical condition characterized by episodes of fainting or syncope,
caused by a sudden drop in heart rate due to a disturbance in the heart's electrical conduction system.
Here are some key points about Stokes-Adams syndrome:
The syndrome is named after two physicians, William Stokes and Robert Adams, who first described
the condition in 1828 and 1827, respectively.
Stokes-Adams syndrome is caused by a blockage or interruption in the electrical signals that regulate
the heartbeat, leading to an abnormally slow heart rate (bradycardia) or even a complete pause in the
heart's rhythm (asystole).
The most common underlying cause of Stokes-Adams syndrome is a type of heart block known as
atrioventricular (AV) block, which occurs when the electrical signals that travel from the atria to the
ventricles are slowed or blocked.
Symptoms of Stokes-Adams syndrome can include dizziness, lightheadedness, fainting, confusion,
chest pain, and shortness of breath.
Treatment of Stokes-Adams syndrome depends on the severity of the symptoms and the underlying
cause of the heart block. Mild cases may be managed with medications such as atropine or
isoproterenol to increase heart rate, while more severe cases may require the implantation of a
pacemaker to regulate the heart's rhythm.
Complications of Stokes-Adams syndrome can include falls and injuries from fainting, as well as more
serious complications such as stroke or sudden cardiac arrest.
Angina Pectoris
1. What are the clinical menifestations of coronary heart disease ? (DU-09Ja)
Coronary heart disease (CHD) is a condition caused by the narrowing or blockage of the coronary
arteries, which supply blood and oxygen to the heart muscle. The clinical manifestations of CHD can
vary widely depending on the degree and location of coronary artery involvement. Some common
clinical manifestations of CHD include:
Chest pain or discomfort: Angina pectoris is the most common symptom of CHD. The pain is
usually described as a tightness, pressure, squeezing, or burning sensation in the chest. It may also
be felt in the arms, neck, jaw, shoulder, or back.
Shortness of breath: This symptom may occur with or without chest pain. It can be caused by
the heart not getting enough oxygen due to reduced blood flow.
4. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Palpitations: This is a sensation of rapid or irregular heartbeat. It may feel like the heart is
skipping a beat or beating too fast.
Fatigue: Reduced blood flow to the heart can cause fatigue or weakness.
Dizziness or lightheadedness: Reduced blood flow to the brain can cause dizziness or
lightheadedness.
Syncope: Fainting may occur due to decreased blood flow to the brain.
Other symptoms: Nausea, vomiting, sweating, and anxiety may also occur.
It is important to note that some people with CHD may not experience any symptoms, especially in the
early stages of the disease.
2. Describe a typical angina. (DU- 07S)
A typical angina, also known as stable angina or exertional angina, is a type of chest pain that occurs
when the heart muscle does not get enough oxygenated blood due to narrowed coronary arteries. The
chest pain is usually described as a squeezing, pressure, heaviness, or tightness in the chest, which may
radiate to the left arm, neck, jaw, shoulder, or back. It is often triggered by physical exertion or
emotional stress and relieved by rest or sublingual nitroglycerin. The pain usually lasts for a few
minutes (up to 10 minutes) and is not associated with shortness of breath, nausea, or diaphoresis.
Patients with typical angina may have a history of atherosclerotic risk factors such as hypertension,
diabetes mellitus, hyperlipidemia, or smoking.
2. Describe a typical angina. (DU- 07S)
Typical angina is a clinical manifestation of coronary artery disease. It is characterized by chest pain or
discomfort that occurs with exertion, emotion, or other types of stress and is relieved by rest or
nitroglycerin. The following are the typical characteristics of angina:
Location: The pain is typically felt behind the sternum or breastbone, but can also be felt in the
left arm, neck, jaw, or shoulders.
Quality: The pain is described as a squeezing, pressure, heaviness, or tightness sensation.
Duration: The pain usually lasts from a few seconds to a few minutes and is relieved by rest or
nitroglycerin.
Triggers: The pain is typically triggered by physical exertion, emotional stress, exposure to cold
temperatures, or after a heavy meal.
5. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Response to nitroglycerin: The pain is relieved by nitroglycerin, a medication that dilates the
coronary arteries, allowing more blood flow to the heart muscle.
These characteristics are used to differentiate typical angina from other types of chest pain, such as
atypical angina, unstable angina, or myocardial infarction.
3. How will you clinical differentiate angina pectoris from esophageal pain?
(DU- 06Ja)
Differentiating angina pectoris from esophageal pain can be challenging because both can present with
similar symptoms such as retrosternal discomfort or burning pain. However, there are some clinical
differences that can help to distinguish between the two conditions:
Onset and duration of pain: Angina pectoris typically presents with sudden onset of pain that
lasts for a few minutes (2-5 minutes), whereas esophageal pain often has a gradual onset and lasts
for a longer duration.
Provoking factors: Angina pectoris is usually provoked by physical or emotional stress, whereas
esophageal pain is often provoked by ingestion of food or acid reflux.
Radiation of pain: Angina pectoris commonly radiates to the left arm, shoulder, neck, jaw or
back, while esophageal pain typically radiates to the back, neck or arms.
Response to nitroglycerin: Nitroglycerin can relieve the symptoms of angina pectoris, but has no
effect on esophageal pain.
Associated symptoms: Angina pectoris may be associated with shortness of breath, sweating or
nausea, while esophageal pain may be associated with heartburn, regurgitation or difficulty
swallowing.
Therefore, taking a detailed history of the patient's symptoms, including the onset, duration, provoking
factors, radiation of pain, and associated symptoms, can help to differentiate angina pectoris from
esophageal pain. In addition, performing a physical examination and specific tests such as an
electrocardiogram (ECG) or an esophageal pH monitoring can also aid in the diagnosis.
How would you investigate a patient with stable angina with expected findings?
(DU-19Nov)
The investigation of a patient with stable angina typically involves the following:
6. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Electrocardiogram (ECG): A resting ECG may show evidence of previous myocardial
infarction (MI) or ischemia. During an angina episode, ECG changes may be present, such as ST-
segment depression or T-wave inversion.
Exercise stress test: A stress test is a commonly used diagnostic test for stable angina. It involves
monitoring the ECG while the patient exercises, usually on a treadmill. The test helps to identify
ischemia-induced changes in the ECG and to determine the patient's exercise capacity.
Echocardiography: This non-invasive imaging test uses sound waves to visualize the heart and
its function. It can help identify structural abnormalities, assess the function of the heart valves,
and estimate the ejection fraction (a measure of the heart's pumping efficiency).
Coronary angiography: This is an invasive diagnostic test that involves injecting a contrast dye
into the coronary arteries and taking X-ray images to visualize any blockages or narrowing in the
arteries. It is usually reserved for patients with high-risk features or those who may require
invasive treatments such as angioplasty or bypass surgery.
Blood tests: Cardiac biomarkers such as troponin may be measured to rule out acute coronary
syndrome as the cause of symptoms.
The expected findings of these investigations depend on the severity and extent of the coronary artery
disease. In stable angina, the ECG may show evidence of previous MI or ischemia, and the exercise
stress test may show evidence of ischemia-induced ECG changes. Echocardiography may show
reduced left ventricular function, and coronary angiography may reveal areas of narrowing or
blockages in the coronary arteries. Blood tests such as troponin are usually normal in stable angina.
In addition to investigating for stable angina, it is also important to investigate for risk factors that may
contribute to the development of coronary artery disease and unstable angina. Some of the
investigations that may be done include:
Lipid profile: This measures the levels of cholesterol and other fats in the blood, which can
contribute to the development of atherosclerosis and subsequent angina.
Fasting blood glucose: This test measures the amount of glucose in the blood after a period of
fasting. Elevated levels can indicate the presence of diabetes, which is a risk factor for coronary
artery disease and angina.
Blood pressure: Elevated blood pressure is a risk factor for the development of coronary artery
disease and angina.
7. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
ECG: This test can identify any abnormalities in the heart's electrical activity, which can indicate
the presence of coronary artery disease and angina.
Stress test: This test involves monitoring the heart's response to physical activity or medication-
induced stress, and can help diagnose the presence of coronary artery disease and angina.
Coronary angiography: This is an invasive test that involves injecting dye into the coronary
arteries to visualize any blockages or narrowing in the vessels. This test is typically reserved for
patients with suspected or confirmed unstable angina.
5. Write down the treatment of angina pectoris (DU-06Ja)
The treatment of angina pectoris may include:
Lifestyle modifications: The patient may be advised to quit smoking, maintain a healthy weight,
exercise regularly, and follow a healthy diet.
Medications: Medications such as nitrates, beta-blockers, calcium channel blockers, and
antiplatelet agents may be prescribed to control symptoms, reduce the risk of complications and
improve outcomes.
Revascularization: Revascularization procedures such as angioplasty or coronary artery bypass
surgery may be recommended in some cases to improve blood flow to the heart and relieve
symptoms.
Education and counseling: Patients with angina should be educated about their condition,
advised to recognize and avoid triggers, and counseled about stress reduction techniques.
Follow-up care: Patients with angina require regular follow-up care to monitor their symptoms,
medications, and risk factors.
What do you mean by unstable angina? (DU- 07S) How would you manage a case
of unstable angina? (DU- 05Ja)
Unstable angina is a type of chest pain or discomfort that occurs when a person is at rest or
experiencing minimal exertion and is considered a medical emergency. It is caused by the disruption of
atherosclerotic plaques in the coronary arteries, leading to partial or complete blockage of blood flow
to the heart muscle.
Management of unstable angina involves immediate hospitalization and treatment to reduce the risk of
heart attack or cardiac arrest. The following steps can be taken:
8. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Oxygen therapy to increase the oxygen supply to the heart
Nitroglycerin to relieve chest pain by dilating the blood vessels
Aspirin or other antiplatelet agents to prevent the formation of blood clots
Heparin or other anticoagulant medications to prevent the formation of blood clots
Beta-blockers to reduce the workload on the heart and lower blood pressure
Statins to lower cholesterol levels and reduce the risk of future cardiovascular events
Invasive procedures such as angiography and percutaneous coronary intervention (PCI) or
coronary artery bypass grafting (CABG) may be necessary to treat underlying coronary artery
disease and prevent future episodes of unstable angina or myocardial infarction.
The specific treatment plan will depend on the severity of the condition and individual patient
factors, and should be determined by a healthcare provider with expertise in managing unstable
angina.
Myocardial Infarction (MI)
*** 1. (a) How would you manage a case of acute myocardial infarction? (DU-
20M)
(a) Management of a case of acute myocardial infarction typically involves the following
steps:
Rapid assessment and stabilization of the patient's condition: The patient's vital signs
and cardiac rhythm should be monitored, and interventions should be made to stabilize
them as needed. Oxygen should be administered to maintain oxygen saturation levels
above 94%. Nitroglycerin and morphine may be given to relieve pain and reduce anxiety.
Early reperfusion therapy: The goal of reperfusion therapy is to restore blood flow to
the affected area of the heart as quickly as possible. This can be achieved through
percutaneous coronary intervention (PCI) or fibrinolytic therapy, depending on the
patient's clinical presentation and the availability of resources.
Antiplatelet and anticoagulant therapy: Antiplatelet therapy with aspirin should be
initiated as soon as possible. Additional anticoagulant therapy with heparin or low-
molecular-weight heparin may also be given.
Beta-blocker therapy: Beta-blockers should be started within the first 24 hours of an
acute myocardial infarction to reduce the risk of subsequent events.
9. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Statin therapy: Statins should be initiated in all patients with acute myocardial
infarction to reduce the risk of recurrent events.
Cardiac rehabilitation: Cardiac rehabilitation should be started as soon as possible to
help the patient recover from the acute event and reduce the risk of future cardiac events.
(b) The management of a case of acute myocardial infarction should be tailored to the
individual patient's clinical presentation and underlying risk factors. The specific
interventions and therapies used will depend on the patient's hemodynamic stability, the
presence of complications, and the availability of resources. In general, the goal of treatment
is to restore blood flow to the affected area of the heart, minimize myocardial damage, and
prevent subsequent events. Close monitoring and prompt intervention are essential to
optimize outcomes.
(b) What are early complications of acute myocardial infarction? (DU-
M)
Some of the early complications of acute myocardial infarction (AMI) include:
Arrhythmias: It is a common complication of AMI and can occur due to damage to
the electrical conduction system of the heart. Arrhythmias can be life-threatening and
include ventricular tachycardia, ventricular fibrillation, and heart block.
Heart failure: AMI can damage a significant portion of the heart muscle, leading to
decreased cardiac function and heart failure.
Cardiogenic shock: In severe cases, AMI can cause cardiogenic shock, which occurs
when the heart is unable to pump enough blood to meet the body's demands.
Pericarditis: Inflammation of the pericardium, the sac surrounding the heart, can
occur after an AMI. This can cause chest pain and other symptoms.
Myocardial rupture: Rarely, the infarcted area of the heart muscle can rupture,
leading to severe internal bleeding and shock.
10. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Ventricular septal defect: AMI can cause a hole to form in the wall that separates
the two lower chambers of the heart, leading to significant hemodynamic compromise.
Mitral regurgitation: Damage to the papillary muscles or the valve itself can lead to
mitral regurgitation, which can cause heart failure and other complications.
Thromboembolic events: Blood clots can form within the heart or in the blood
vessels leading to or from the heart, leading to stroke or other thromboembolic events.
Mention the principles of management of acute myocardial infarction.
(DU- 19M)
The principles of management of acute myocardial infarction include:
Early recognition and diagnosis: Prompt recognition of MI symptoms and confirmation
through diagnostic tests such as electrocardiogram (ECG), cardiac biomarkers (troponin, CK-
MB), and imaging studies (echocardiography, coronary angiography).
Reperfusion therapy: Restoration of blood flow to the ischemic myocardium through either
primary percutaneous coronary intervention (PCI) or fibrinolytic therapy. The choice of
therapy depends on the availability, time to treatment, and patient's clinical characteristics.
Pharmacological therapy: Administration of antiplatelet agents, anticoagulants, beta-
blockers, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers
(ARBs), and lipid-lowering agents such as statins.
Monitoring and supportive care: Continuous monitoring of vital signs, ECG, and cardiac
biomarkers for any signs of worsening or complications such as arrhythmias, heart failure, or
cardiogenic shock. Oxygen therapy, pain relief, and hemodynamic support may also be
necessary.
Risk factor modification and secondary prevention: Implementation of lifestyle
modifications such as smoking cessation, healthy diet, regular exercise, and stress reduction,
as well as initiation of medications for secondary prevention of cardiovascular events such as
aspirin, statins, and ACEIs/ARBs.
Cardiac rehabilitation: A structured program of exercise training, risk factor modification,
and psychosocial support to improve functional capacity and quality of life after an acute MI.
11. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Describe the characteristics of chest pain of acute myocardial
infarction. (DU-18Nov)
The characteristics of chest pain in acute myocardial infarction (AMI) are as follows:
Location: The pain is typically felt in the center of the chest behind the sternum, although it
can also radiate to the left arm, neck, jaw, back, or epigastrium.
Quality: The pain is usually described as a pressure, squeezing, tightness, or burning
sensation. It is often compared to a feeling of an elephant sitting on the chest or a heavy
weight.
Severity: The pain is usually severe and intense, often described as the worst pain ever
experienced.
Duration: The pain lasts for more than 20 minutes, but can last for several hours or longer.
Associated symptoms: The pain is often associated with other symptoms such as sweating,
shortness of breath, nausea, vomiting, dizziness, and palpitations.
Trigger factors: The pain may be triggered by physical or emotional stress, or may occur at
rest.
It is important to note that not all patients with AMI will experience chest pain, especially in the elderly,
women, and patients with diabetes. Therefore, other symptoms such as dyspnea, diaphoresis, nausea, or
vomiting may be the presenting features of AMI.
3. A 55 year old man has presented with central chest pain
precipitating with physical excretion & cold exposure, relieving with
taking rest for 3 months. On precordium auscultation, there is no
murmur. (DU-21M)
a. What is the most likely clinical diagnosis? Mention 2 (two) other features to differentiate
from musculoskeletal chest pain.
b. Write down the risk factors of the above condition.
12. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
a. The most likely clinical diagnosis is stable angina. Two features to differentiate from
musculoskeletal chest pain are:
The pain is typically precipitated by physical exertion or emotional stress and relieved by rest
or sublingual nitroglycerin.
The pain is described as a squeezing, pressure, heaviness, or tightness sensation in the chest,
often with radiation to the left arm, neck, jaw, or back.
b. The risk factors of stable angina include:
Age (more common in older adults)
Male gender
Smoking
High blood pressure
High cholesterol levels
Diabetes
Family history of premature coronary artery disease
Obesity or overweight
Sedentary lifestyle
4. a. A 45 year old male presents with sudden severe chest pain
for 6 hours and ECG evidence is in favour of acute myocardial
infarction. How will you search for underlying risk factors?
In a patient with acute myocardial infarction, it is important to search for underlying risk factors that
may contribute to the development of the condition and affect the management plan. Some of the
common risk factors for myocardial infarction include:
Age: Older age increases the risk of developing myocardial infarction.
Family history of heart disease: Individuals with a family history of heart disease are at a
higher risk of developing myocardial infarction.
Smoking: Smoking is a major risk factor for myocardial infarction.
High blood pressure: Individuals with high blood pressure are at an increased risk of
myocardial infarction.
High cholesterol: High levels of cholesterol in the blood can increase the risk of myocardial
infarction.
Diabetes: Individuals with diabetes are at a higher risk of developing myocardial infarction.
Obesity: Being overweight or obese increases the risk of myocardial infarction.
13. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Sedentary lifestyle: Lack of physical activity can increase the risk of myocardial infarction.
Stress: Chronic stress can increase the risk of developing myocardial infarction.
To search for underlying risk factors in a patient with acute myocardial infarction, a detailed history
and physical examination should be performed. This may include asking about family history, smoking
history, dietary habits, exercise habits, and medical history (such as diabetes or hypertension). Blood
tests, such as lipid profile and glucose level, can also be performed to assess for underlying risk factors.
b. Mention the clinical conditions related to excess environment heat.
(DU-17Ja)
Clinical conditions related to excess environmental heat include:
Heat cramps: painful muscle spasms that occur during or after intense exercise in hot
environments
Heat exhaustion: a condition characterized by heavy sweating, weakness, dizziness, nausea,
and headache due to dehydration and electrolyte imbalance
Heat syncope: fainting or dizziness caused by a sudden drop in blood pressure due to
standing for prolonged periods in a hot environment
Heat rash: small red bumps or blisters on the skin due to sweating and clogged sweat ducts
Heatstroke: a life-threatening condition characterized by a body temperature of 104°F or
higher, confusion, seizures, and loss of consciousness. It is considered a medical emergency
and requires immediate treatment.
5. A 60 year old smoker is admitted with acute central chest pain for 2 hours. His
ECG shows ST elevation. (DU-16Ja)
a. What immediate management would you take for the patient?
The immediate management for the patient with acute central chest pain and ST elevation on
ECG would be to initiate reperfusion therapy as soon as possible. This can be done with either
fibrinolytic therapy or primary percutaneous coronary intervention (PCI) depending on the
available resources and the time since the onset of symptoms.
Other immediate management measures would include administering oxygen to maintain
oxygen saturation above 94%, initiating antiplatelet therapy with aspirin and P2Y12 inhibitors,
and providing pain relief with intravenous morphine. The patient should also be closely
monitored for complications such as ventricular arrhythmias and cardiogenic shock
14. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Call for emergency medical services to transfer the patient to the nearest hospital
with a cardiac catheterization laboratory and 24-hour primary percutaneous coronary
intervention (PCI) capabilities.
Administer aspirin chewable tablet of 300 mg or 4 tablets of 75 mg each orally, and
nitroglycerin sublingual tablet or spray every 5 minutes up to three doses as needed to
relieve chest pain.
Initiate oxygen therapy with a target saturation level of at least 94%.
Administer a loading dose of a P2Y12 inhibitor (e.g., clopidogrel 600 mg,
prasugrel 60 mg, or ticagrelor 180 mg) orally or through a nasogastric tube.
Perform an electrocardiogram (ECG) and repeat it every 10-15 minutes if there is
persistent chest pain.
Obtain venous access and start an intravenous infusion of heparin or bivalirudin, a
direct thrombin inhibitor.
Monitor blood pressure, heart rate, oxygen saturation, and ECG changes
continuously.
Consider providing analgesia with opioids if chest pain persists despite the
administration of nitroglycerin.
Reevaluate the patient and consider the need for urgent revascularization by primary
PCI or thrombolytic therapy in consultation with a cardiologist.
It is crucial to remember that the management of acute myocardial infarction is time-sensitive,
and early recognition and prompt treatment can save lives and prevent complications.
b. The patient develops dyspnoea on the following day. What additional
measures will you take to manage the patient?
If the patient develops dyspnea following an acute myocardial infarction, it may suggest the
development of heart failure or a complication such as a ventricular septal defect. The
following additional measures may be taken to manage the patient:
Administer supplemental oxygen to improve oxygen saturation levels and relieve
dyspnea.
Administer diuretics to reduce fluid overload and relieve dyspnea associated with
heart failure.
Administer nitrates to dilate blood vessels and reduce cardiac workload, thereby
relieving dyspnea.
Monitor vital signs, fluid balance, and urine output to assess the patient's response to
treatment and detect any signs of worsening heart failure.
15. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Consider further investigations such as echocardiography to assess the patient's left
ventricular function and identify any complications such as ventricular septal defect.
Consult with a cardiologist for further management and possible interventions, such
as cardiac catheterization or coronary artery bypass graft surgery, depending on the
underlying cause of the dyspnea.
6. a. What is acute coronary syndrome? How do confirm acute
myocardial infraction? (DU-15Ju)
Acute coronary syndrome (ACS) refers to a group of clinical conditions that are caused by a
sudden reduction or occlusion of blood flow to the heart due to coronary artery disease. The
three clinical conditions that make up ACS are unstable angina, non-ST segment elevation
myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI).
To confirm acute myocardial infarction (AMI), several diagnostic tests can be used, including:
Electrocardiogram (ECG): An ECG measures the electrical activity of the heart and
can detect changes in the heart's rhythm and electrical conduction. In AMI, the ECG
may show ST-segment elevation, indicating myocardial injury.
Cardiac biomarkers: These are blood tests that measure the levels of enzymes and
proteins released by damaged heart muscle cells. Elevated levels of cardiac
biomarkers such as troponin indicate myocardial damage and help to confirm the
diagnosis of AMI.
Imaging studies: Imaging studies such as echocardiography or cardiac MRI may be
used to assess the extent and severity of myocardial damage and to help guide
treatment decisions.
b. What is the difference between NSTEMI and STEMI? (DU-15Ju)
The main difference between NSTEMI and STEMI is the extent and severity of myocardial
damage. In NSTEMI, the blood flow to the heart is partially occluded, and there is partial
myocardial damage. In contrast, in STEMI, there is complete occlusion of the coronary artery,
leading to complete myocardial damage.
16. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Other differences between NSTEMI and STEMI include:
ECG changes: In NSTEMI, the ECG may show ST-segment depression or T-wave
inversion, indicating myocardial ischemia. In STEMI, the ECG typically shows ST-
segment elevation, indicating myocardial injury.
Cardiac biomarkers: In both NSTEMI and STEMI, cardiac biomarkers such as
troponin are elevated, but the levels are typically higher in STEMI due to the more
extensive myocardial damage.
Treatment: The treatment of NSTEMI and STEMI differs, with STEMI requiring
more urgent and aggressive intervention, such as reperfusion therapy, to restore blood
flow to the affected area of the heart. NSTEMI is usually managed with medical
therapy and may require less urgent intervention.
b. Mention immediate management of this condition. Mention the
principles of management of acute coronary syndrome (DU-18Ju)
Immediate management of acute coronary syndrome includes:
Administering aspirin: Aspirin is a blood thinner and helps in preventing the formation of
blood clots. It should be chewed or crushed and swallowed immediately after a heart attack is
suspected.
Administering nitroglycerin: Nitroglycerin helps in relaxing the blood vessels and easing the
workload on the heart. It should be given sublingually (under the tongue) or intravenously.
Administering morphine: Morphine helps in relieving the pain associated with acute
coronary syndrome. It also reduces the workload on the heart.
Supplemental oxygen: Oxygen should be given to the patient to ensure adequate oxygen
supply to the heart.
Beta-blockers: Beta-blockers help in reducing the workload on the heart and are given orally
or intravenously.
The principles of management of acute coronary syndrome include:
17. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Early recognition: Acute coronary syndrome should be recognized as early as possible, and
treatment should be started immediately.
Prompt revascularization: Revascularization, either through angioplasty or bypass surgery,
should be done as soon as possible to restore blood flow to the affected area of the heart.
Pharmacological therapy: Medications such as aspirin, nitroglycerin, beta-blockers, and
statins should be given to manage the symptoms and reduce the risk of future cardiovascular
events.
Risk factor management: Risk factors such as hypertension, diabetes, and high cholesterol
should be managed to prevent future cardiovascular events.
Cardiac rehabilitation: Cardiac rehabilitation, including physical exercise, lifestyle
modifications, and stress management, should be initiated to improve the patient's overall
cardiovascular health and prevent future events.
7. Name the enzymes those may be elevated in acute MI. (DU-09Ja)
In the context of acute MI, the following enzymes may be elevated:
Creatine kinase (CK-MB): CK-MB levels rise 3-6 hours after MI onset and peak at 12-24
hours. It returns to normal within 2-3 days.
Troponin I or T: Troponin levels rise 3-6 hours after MI onset and remain elevated for up to
2 weeks.
Myoglobin: Myoglobin levels rise within 2-3 hours after MI onset and peak within 6-9 hours.
It returns to normal within 24 hours.
Elevation of these enzymes in the appropriate clinical context can help confirm the diagnosis of acute
MI.
8. Write down the management of acute MI (DU-10Ju)
Management of Acute Myocardial Infarction (MI) involves the following steps:
Initial assessment and stabilization:
This includes monitoring vital signs, administering oxygen therapy, establishing IV access, providing
pain relief with medications such as nitroglycerin and morphine, and assessing the need for urgent
reperfusion therapy.
Reperfusion therapy:
18. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
The aim of reperfusion therapy is to restore blood flow to the blocked coronary artery as soon as
possible. It can be achieved either by primary percutaneous coronary intervention (PCI) or
thrombolytic therapy. Primary PCI is preferred if it can be performed within 90 minutes of first medical
contact.
Antiplatelet and anticoagulant therapy:
Aspirin is given immediately and continued indefinitely. Other antiplatelet agents such as clopidogrel
or ticagrelor are also given. Anticoagulant therapy with heparin or enoxaparin is started and continued
for several days.
Beta-blocker therapy:
Beta-blockers are given to reduce the risk of recurrent MI, arrhythmias, and heart failure. They should
be started as soon as possible and continued indefinitely.
ACE inhibitors/ARBs:
These drugs are given to reduce the risk of recurrent MI, heart failure, and death. They should be
started within the first 24 hours of MI and continued indefinitely.
Statin therapy:
Statins are given to reduce LDL cholesterol levels and decrease the risk of recurrent MI and death.
They should be started as soon as possible and continued indefinitely.
Cardiac rehabilitation:
This involves exercise training, lifestyle modification, and risk factor reduction. It should be started as
soon as possible after discharge and continued for several weeks to months.
Complication management:
Management of complications such as heart failure, cardiogenic shock, arrhythmias, and mechanical
complications such as papillary muscle rupture or ventricular septal defect should be done promptly.
Long-term follow-up:
Patients with acute MI should be followed up regularly for several years to monitor for recurrent events
and optimize secondary prevention measures.
9. A 45 year old male presents with sudden severe chest pain for 1 hour.
(DU- 19Ja)
a. Make a check list history and physical signs to find out the causes.
b. How would you manage this case?
a. Check list history and physical signs to find out the causes of sudden severe chest pain in a 45-year-
old male:
History:
Time of onset of pain
Duration and frequency of pain
19. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Quality and intensity of pain
Radiation of pain
Any associated symptoms like sweating, nausea, vomiting, breathlessness, palpitation,
dizziness, or syncope
Any past history of similar episodes
Any past medical history of hypertension, diabetes mellitus, dyslipidemia, smoking, or family
history of coronary artery disease
Physical examination:
Vital signs: blood pressure, heart rate, respiratory rate, and oxygen saturation
Cardiac examination: rhythm, rate, murmurs, and gallops
Respiratory examination: breath sounds, crepitations, or wheezing
Abdominal examination: tenderness, guarding, or distension
Neurological examination: level of consciousness, pupils, and motor power
b. Management of a case with sudden severe chest pain for 1 hour:
Assess the ABCs (airway, breathing, and circulation)
Administer oxygen via a nasal cannula at a flow rate of 4-6 L/min
Administer aspirin 300mg orally or 150-300mg chewed and swallowed as soon as possible
Administer sublingual glyceryl trinitrate (GTN) 0.4 mg every 5 minutes up to a maximum of 3
doses, if there is no contraindication
Obtain a 12-lead electrocardiogram (ECG) as soon as possible
Consider early reperfusion therapy if indicated (thrombolytic therapy or primary percutaneous
coronary intervention) within 12 hours of the onset of symptoms
Administer morphine sulfate 2-4mg intravenously, if there is no contraindication and the pain
persists after treatment with GTN
Monitor the patient's vital signs and cardiac rhythm closely
Admit the patient to the coronary care unit for further management and observation
10. A 60 year old man has been admitted with severe central chest pain. His ECG
shows ST elevation. (DU-14Ju)
a. How do you manage the patient in a Medical College Hospital?
b. The patient developed dyspnoea on the following day. What additional measures will
you take to manage the patient?
a. The management of the patient with severe central chest pain and ST elevation on ECG in a Medical
College Hospital typically involves the following steps:
20. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Rapid assessment: The patient should be assessed quickly to determine the severity of their
condition and the need for urgent intervention.
Oxygen therapy: Oxygen should be administered immediately to improve oxygenation.
Pain relief: Analgesics such as morphine sulfate or fentanyl should be given for pain relief.
Antiplatelet therapy: Aspirin should be given as soon as possible to reduce the risk of further
cardiac events.
Reperfusion therapy: If available, reperfusion therapy (such as thrombolysis or primary
percutaneous coronary intervention) should be initiated within the recommended time frame
to restore blood flow to the affected area of the heart.
Monitoring: The patient should be monitored closely for any changes in their condition,
including vital signs, ECG, and cardiac enzymes.
Risk factor management: The patient should receive counseling and interventions to manage
their risk factors for cardiovascular disease, such as smoking cessation, blood pressure control,
and lipid management.
b. If the patient develops dyspnea on the following day after an acute myocardial infarction, additional
measures may be needed to manage their condition, including:
Oxygen therapy: Supplemental oxygen should be given to maintain oxygen saturation levels.
Diuretics: Diuretics may be used to reduce fluid overload and relieve pulmonary congestion.
Nitrates: Nitrates such as nitroglycerin may be given to reduce the workload of the heart and
improve symptoms.
ACE inhibitors: ACE inhibitors may be started to reduce the risk of further cardiac events
and improve outcomes.
Monitoring: The patient should be monitored closely for any signs of worsening heart failure,
including changes in vital signs, ECG, and cardiac enzymes.
11. A 45 years old male smoker presented with chest pain. (DU-13Ju, 10Ju)
a. Mention the important characteristics of pain which will suggest MI.
21. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
b. Give an outline of management of acute myocardial infraction.
a. The important characteristics of chest pain suggestive of myocardial infarction are:
Sudden onset of pain
Chest pain that is severe and crushing in nature
Pain that radiates to the left arm, neck, jaw, back, or shoulder
Pain that is not relieved by rest or nitroglycerin
Pain that lasts for more than 20 minutes
b. The management of acute myocardial infarction includes the following steps:
Aspirin: Administer 325mg of aspirin as soon as possible.
Oxygen: Administer oxygen if the patient is hypoxic.
Nitroglycerin: Administer sublingual nitroglycerin for chest pain.
Analgesics: Administer pain relief, such as morphine, if the patient has persistent chest pain.
Reperfusion: Reperfusion therapy should be given within 12 hours of symptom onset. This
includes either thrombolytic therapy or percutaneous coronary intervention (PCI).
Anticoagulants: Administer anticoagulant therapy, such as heparin or low molecular weight
heparin.
Antiplatelet therapy: Administer antiplatelet therapy, such as clopidogrel or ticagrelor.
Beta blockers: Administer beta blockers in the absence of contraindications.
ACE inhibitors or ARBs: Administer angiotensin-converting enzyme (ACE) inhibitors or
angiotensin receptor blockers (ARBs) in the absence of contraindications.
Statins: Administer statins to all patients with acute myocardial infarction.
In addition to the above steps, it is important to monitor the patient for complications and provide
appropriate management. Close monitoring of vital signs, cardiac rhythm, and oxygen saturation is
necessary. Patients with cardiogenic shock may require mechanical support, such as an intra-aortic
balloon pump. Patients with arrhythmias may require antiarrhythmic therapy or electrical cardioversion.
12. A 50 years old smoker presents with acute central chest pain. (DU-12Ju)
a. What historical features and physical sign will suggest acute coronary syndrome?
b. Mention the immediate management measures in this case.
a. Historical features and physical signs that may suggest acute coronary syndrome in a 50-year-
old smoker with acute central chest pain include:
Sudden onset of pain
Crushing or squeezing pain, often described as "heaviness" or "tightness"
Pain may radiate to the arms (usually left), neck, jaw, back or upper abdomen
Shortness of breath
22. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Nausea or vomiting
Sweating
Pallor or grayish color of the skin
Irregular heartbeat
Decreased blood pressure
Physical examination may reveal:
Rapid or irregular heartbeat
Low blood pressure
Crackles in the lungs (suggesting heart failure)
Murmurs (suggesting valvular heart disease)
b. The immediate management measures for a patient with acute coronary syndrome include:
Oxygen therapy: to maintain oxygen saturation above 94%
Aspirin: to prevent further clotting
Nitroglycerin: to relieve chest pain and improve blood flow
Morphine: if nitroglycerin fails to relieve pain or if the patient is anxious
Beta blockers: to reduce heart rate and blood pressure and prevent further damage to the heart
muscle
Anticoagulants: to prevent further clotting and reduce the risk of stroke
Reperfusion therapy: either fibrinolytic therapy or percutaneous coronary intervention (PCI)
to restore blood flow to the heart muscle.
After the immediate management measures, the patient will need further evaluation, risk stratification
and long-term management to prevent further cardiac events.
* 13. Give complications of MI. (DU-11Ja, 10Ja)
Complications of MI (Myocardial Infarction) can include:
Arrhythmias: Abnormal heart rhythms due to the damage to the heart muscle can lead to
various types of arrhythmias, including ventricular tachycardia or fibrillation, which can be
life-threatening.
Heart failure: MI can lead to heart failure, which occurs when the heart can't pump enough
blood to meet the body's needs. This can lead to symptoms such as shortness of breath, fatigue,
and swelling in the legs and ankles.
Cardiogenic shock: This is a severe form of heart failure where the heart is unable to pump
enough blood to the vital organs, leading to organ failure and potentially death.
Pericarditis: Inflammation of the lining surrounding the heart can occur following an MI.
23. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Thrombosis and embolism: Blood clots can form in the damaged heart muscle and may
break off and travel to other parts of the body, causing blockages.
Ventricular aneurysm: MI can lead to a bulge in the weakened heart muscle, which can
cause arrhythmias, heart failure, and further MI.
Dressler's syndrome: This is a rare autoimmune response to an MI, which can cause fever,
chest pain, and pericarditis.
Stroke: Blood clots formed during MI can break off and travel to the brain, causing a stroke.
Post-infarction angina: Chest pain can persist even after the MI has resolved.
Sudden cardiac death: This can occur due to arrhythmias or other complications of MI.
1. A 30 years old man recently detected as having hypertension. (DU-
20m)
(a) Make a check list of clinical history to find out the causes of hypertension.
(b) Write down the investigation plan for him.
(a) Check list of clinical history to find out the causes of hypertension:
Family history of hypertension
History of previous kidney disease or renal abnormalities
Sleep apnea or other respiratory issues
Hormonal disorders such as thyroid disease or Cushing's syndrome
Alcohol consumption
Smoking history
Drug history, including over-the-counter medications and illegal substances
Dietary habits and physical activity levels
Stressful life events or chronic stress
(b) Investigation plan for a patient with hypertension may include:
Blood tests: To check for any underlying health conditions, such as diabetes, kidney disease,
or high cholesterol.
Urine tests: To check for any kidney abnormalities or protein in the urine.
ECG (Electrocardiogram): To check for any abnormalities in heart rhythm or structure.
24. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
drtoufiq19711@yahoo.com; drtoufiq1971@gmail.com
Ambulatory blood pressure monitoring (ABPM): A 24-hour blood pressure measurement
to assess blood pressure variability and determine if the patient has white-coat hypertension or
masked hypertension.
Echocardiogram: To evaluate the structure and function of the heart and to rule out any
underlying heart disease.
Imaging tests: Such as CT scan, MRI, or angiography to evaluate blood vessels and to check
for any abnormalities that may be contributing to hypertension.
Stress test: To evaluate the patient's heart function during exercise and to determine the
presence of any underlying heart disease.
Genetic testing: In some cases, genetic testing may be performed to determine if the patient
has a genetic predisposition to hypertension or underlying heart disease.
The investigation plan may vary based on the individual patient's history, symptoms, and physical
examination findings.
2. A 35 year old male recently detected as hypertension for 3 months. (DU-19Ja)
a. Make a check list and physical sign to find out the causes of hypertension.
b. Write down the investigation plan for him.
a. The checklist and physical signs to find out the causes of hypertension in a 35-year-old male
are:
Checklist:
Family history of hypertension
History of kidney disease
History of diabetes mellitus
Lifestyle factors: diet, exercise, tobacco and alcohol use
Medication history
Endocrine disorders such as Cushing's syndrome or hyperthyroidism
Sleep apnea
Physical signs:
Elevated blood pressure reading on at least two occasions
Evidence of end-organ damage such as retinal changes, proteinuria, or left ventricular
hypertrophy
Obesity
Thyroid enlargement or nodules
Abdominal bruit
Palpable renal masses
25. Professor DR Md . TOUFIQUR RAHMAN , FCPS, MD
Professor & Head, Cardiology, CMMC, Manikganj
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b. The investigation plan for a 35-year-old male with hypertension may include:
Complete blood count (CBC)
Fasting blood glucose level
Lipid profile
Renal function tests including serum creatinine, blood urea nitrogen (BUN), and estimated
glomerular filtration rate (eGFR)
Urinalysis
Electrocardiogram (ECG)
Echocardiogram
Chest X-ray
Thyroid function tests
Sleep study (if sleep apnea is suspected)
24-hour urine collection for catecholamines and metanephrines (if pheochromocytoma is
suspected)
Additional tests may be ordered based on the initial findings and clinical suspicion. The investigation
plan should also include regular monitoring of blood pressure and close follow-up with a healthcare
provider to assess response to treatment and adjust management accordingly.