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Introduction to the Nervous System and Nerve Tissue
Three Basic Functions
1. Sensory Functions: Sensory receptors detect both internal
and external stimuli.
Functional unit: Sensory or Afferent Neurons
2. Integrative Functions: CNS integrates sensory input and
makes decisions regarding appropriate responses
Functional Unit: Interneurons or Association
Neurons of the Brain and Spinal cord
3. Motor Functions: Response to integration decisions.
Functional Unit: Motor or Efferent Neurons
Organization of the Nervous System
to supply the three basic functions
Introduction to the Nervous System
and Nerve Tissue
Introduction to the Nervous System and Nerve Tissue
Organization of the CNS
Gray Matter: Contains neuron cell bodies
W
White Matter: Contains cell extensions organized into tracts
Organization of the CNS
Organization of a Nerve of the PNS
Introduction to the Nervous System and Nerve Tissue
Structure of a Neuron
Dendrites: Carry nerve
impulses toward cell body.
Receive stimuli from synapses
or sensory receptors.
Cell Body: Contains nucleus
and nissl bodies, a form of
rough endoplasmic reticulum.
Axon: Carry nerve Impulses
away from the cell bodies.
Axons interact with muscle,
glands, or other neurons.
Multipolar “Motor” Neuron
Node of Ranvier
Introduction to the Nervous System and Nerve Tissue
Types of Neurons
Introduction to the Nervous System and Nerve Tissue
Types of Interneurons
Schwann cells--are the
supporting cells of the
PNS. Schwann cells
wrap themselves
around nerve axons, a
single Schwann cell
makes up a single segment
of an axon's myelin sheath.
Introduction to the Nervous System and Nerve
Tissue
Nervous System Physiology:
Distribution of Ions between
ECF and ICF
Nervous System Physiology:
Nerve Conduction Occurs because of
Changes in Membrane Potential
Nervous System Physiology:
Types of Channel Proteins
Nervous System Physiology:
Mechanism that creates an Action
Potential
Nervous System Physiology:
Two Mechanisms of Action Potential
Conduction along a neuron
Nervous System Physiology:
Communication between neurons
at a synaptic junction
1. Electrical Synapses: Communication via gap junctions
between smooth muscle, cardiac muscle, and
some neurons of the CNS. Provide fast,
synchronized, and two-way transmission of
information.
2. Chemical Synapses: Communication via chemical
neurotransmitters that diffuse across a
synaptic
cleft. Provides slow one-way information flow
Nervous System Physiology:
Communication between neurons
at a synaptic junction
Action potential arrives at
a synaptic end bulb.
Depolarization of membrane
causes the opening of Ca2+
channels.
Increase in (Ca2+) inside of
presynaptic neuron triggers
exocytosis of neurotransmitter
Neurotransmitter diffuses across
synaptic cleft and binds to
receptor (ligand-gated channel)
on postsynaptic neuron
Nervous System Physiology:
Communication between neurons
at a synaptic junction
5. Na+ channels open causing a
depolarization (Na+ channels)
EPSP (excitatory postsynaptic
potential) or a
hyperpolarization (Cl-
channels) IPSP (inhibitory post-
synaptic potential) of the
postsynaptic neuron.
6. If depolarization reaches a
threshold, an action potential is
generated on the postsynaptic
neuron.
Nervous System Physiology:
Communication between neurons
at a synaptic junction
Nervous System Physiology:
Communication between neurons
at a synaptic junction
Neurotransmitters
1. Acetylcholine: Found in the
PNS and CNS. EPSP and in
parasympathetic neurons IPSP.
2. Amino Acids: Glutamate and
Aspartate produce EPSP’s in the
CNS. Gamma Aminobutyric
Acid (GABA) produces IPSP’s
in the CNS. Valium enhances the
action of GABA.
Nervous System Physiology:
Communication between neurons at a synaptic
junction
Neurotransmitters
3. Biogenic Amines:
Norepinephrine and epinephrine
produce EPSP’s in the
sympathetic system. Serotonin
controls mood and induction of
sleep.
4. Gases: Nitric Oxide produce by
the enzyme nitric oxide synthase.
Causes vasodilation and
erection.
Nervous System Physiology:
Communication between neurons
at a synaptic junction
Types of Neural Circuits

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Introduction to the nervous system and nerve tissue[1]

  • 1. Introduction to the Nervous System and Nerve Tissue Three Basic Functions 1. Sensory Functions: Sensory receptors detect both internal and external stimuli. Functional unit: Sensory or Afferent Neurons 2. Integrative Functions: CNS integrates sensory input and makes decisions regarding appropriate responses Functional Unit: Interneurons or Association Neurons of the Brain and Spinal cord 3. Motor Functions: Response to integration decisions. Functional Unit: Motor or Efferent Neurons
  • 2. Organization of the Nervous System to supply the three basic functions
  • 3. Introduction to the Nervous System and Nerve Tissue
  • 4. Introduction to the Nervous System and Nerve Tissue
  • 5. Organization of the CNS Gray Matter: Contains neuron cell bodies W White Matter: Contains cell extensions organized into tracts
  • 7. Organization of a Nerve of the PNS
  • 8. Introduction to the Nervous System and Nerve Tissue Structure of a Neuron Dendrites: Carry nerve impulses toward cell body. Receive stimuli from synapses or sensory receptors. Cell Body: Contains nucleus and nissl bodies, a form of rough endoplasmic reticulum. Axon: Carry nerve Impulses away from the cell bodies. Axons interact with muscle, glands, or other neurons.
  • 11. Introduction to the Nervous System and Nerve Tissue Types of Neurons
  • 12. Introduction to the Nervous System and Nerve Tissue Types of Interneurons
  • 13. Schwann cells--are the supporting cells of the PNS. Schwann cells wrap themselves around nerve axons, a single Schwann cell makes up a single segment of an axon's myelin sheath. Introduction to the Nervous System and Nerve Tissue
  • 14. Nervous System Physiology: Distribution of Ions between ECF and ICF
  • 15. Nervous System Physiology: Nerve Conduction Occurs because of Changes in Membrane Potential
  • 16. Nervous System Physiology: Types of Channel Proteins
  • 17. Nervous System Physiology: Mechanism that creates an Action Potential
  • 18. Nervous System Physiology: Two Mechanisms of Action Potential Conduction along a neuron
  • 19. Nervous System Physiology: Communication between neurons at a synaptic junction 1. Electrical Synapses: Communication via gap junctions between smooth muscle, cardiac muscle, and some neurons of the CNS. Provide fast, synchronized, and two-way transmission of information. 2. Chemical Synapses: Communication via chemical neurotransmitters that diffuse across a synaptic cleft. Provides slow one-way information flow
  • 20. Nervous System Physiology: Communication between neurons at a synaptic junction Action potential arrives at a synaptic end bulb. Depolarization of membrane causes the opening of Ca2+ channels. Increase in (Ca2+) inside of presynaptic neuron triggers exocytosis of neurotransmitter Neurotransmitter diffuses across synaptic cleft and binds to receptor (ligand-gated channel) on postsynaptic neuron
  • 21. Nervous System Physiology: Communication between neurons at a synaptic junction 5. Na+ channels open causing a depolarization (Na+ channels) EPSP (excitatory postsynaptic potential) or a hyperpolarization (Cl- channels) IPSP (inhibitory post- synaptic potential) of the postsynaptic neuron. 6. If depolarization reaches a threshold, an action potential is generated on the postsynaptic neuron.
  • 22. Nervous System Physiology: Communication between neurons at a synaptic junction
  • 23. Nervous System Physiology: Communication between neurons at a synaptic junction Neurotransmitters 1. Acetylcholine: Found in the PNS and CNS. EPSP and in parasympathetic neurons IPSP. 2. Amino Acids: Glutamate and Aspartate produce EPSP’s in the CNS. Gamma Aminobutyric Acid (GABA) produces IPSP’s in the CNS. Valium enhances the action of GABA.
  • 24. Nervous System Physiology: Communication between neurons at a synaptic junction Neurotransmitters 3. Biogenic Amines: Norepinephrine and epinephrine produce EPSP’s in the sympathetic system. Serotonin controls mood and induction of sleep. 4. Gases: Nitric Oxide produce by the enzyme nitric oxide synthase. Causes vasodilation and erection.
  • 25. Nervous System Physiology: Communication between neurons at a synaptic junction
  • 26. Types of Neural Circuits