www.ophthalclass.blogspot.com has the complete class on uveitis for undergraduate medical students. This presentation is the fourth in the series and deals with the management of uveitis.
This is appt presentation done by me and my colleagues zakaria Abul-Nasser and Sara Hassan ( agroup of medical undergarduates , school of Medicine, Ain-shams university , Cairo , Egypt ) ...
This work was presented at the end of our Ophthalmolgy clinical round ..
I Hope every one to get the best out of the presentaion ..Any commentaries are even more appreciated :)
This is appt presentation done by me and my colleagues zakaria Abul-Nasser and Sara Hassan ( agroup of medical undergarduates , school of Medicine, Ain-shams university , Cairo , Egypt ) ...
This work was presented at the end of our Ophthalmolgy clinical round ..
I Hope every one to get the best out of the presentaion ..Any commentaries are even more appreciated :)
Uveitis is an interesting disease of the with such a varied and diverse pathogenesis, various systemic causes and Dangerous complications in relation to the eye which makes it difficult and challenging to treat in a proper way. I hope this share will help.
www.ophthalclass.blogspot.com has the complete post.
In Part1 the topics discussed are the causes of anterior, intermediate, posterior and panuveitis. There is also a section on the associated features like history, demographics and examination findings that help to narrow down the differential diagnosis.
www.ophthalclass.blogspot.com has the complete class on uveitis for undergraduate medical students. This presentation is the first in the series and deals with the classification of uveitis.
www.ophthalclass.blogspot.com has the complete class and MCQs on uveitis for undergraduate medical students. Class 5 in the series of classes on uveitis deals with the common causes of panuveitis and briefly discusses their management. The clinical feature of each of the disease entities is explained with the help of case studies.
www.ophthalclass.blogspot.com has the complete class on uveitis for undergraduate medical students. This presentation is the third in the series and deals with the sequelae and complications of uveitis.
www.ophthalclass.blogspot.com has the complete class on uveitis for undergraduate medical students. This presentation is the second part of the introductory class in the series and deals with the clinical features of uveitis.
Lecture on Management of Cataract Surgery and Diabetes Mellitus. 2010 World Congress, American Society of Cataract & Refractive Surgery. Boston, MA 2010
Opthalmic emergencies /certified fixed orthodontic courses by Indian dental a...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Opthalmic emergencies /certified fixed orthodontic courses by Indian dental a...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Opthalmic emergencies /certified fixed orthodontic courses by Indian dental a...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
This lecture is about the different types of blunt trauma,presentation and management of the various forms of blunt trauma.Its complications and their approach.the Le Fort fractures
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
1. Management of uveitis
DR. ANUPAMA KARANTH
www.ophthalclass.blogspot.com
www.ophthalclass.blogspot.com
2. Anti-inflammatory agents
‘-itis’ = inflammation
Treatment : stop inflammation
Use anti-inflammatory drugs
Most potent of such agents : Corticosteroids
Corticosteroids are the mainstay of therapy in uveitis
www.ophthalclass.blogspot.com
3. Complicating the issue
What if the cause is infectious?
Specific anti-infective agent is indicated
Corticosteroids may even worsen the infection when given
alone
When the cause is immune related?
Corticosteroids will be effective
Associated side effects maybe significant
www.ophthalclass.blogspot.com
4. Management of uveitis
Finding the etiology
Narrow down list of differentials by history and examination
Appropriate investigations (ocular and systemic)
Referrals for systemic associations
Treating the inflammation
Specific therapy
Non-specific therapy
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5. Few ocular investigations
Fundus fluorescein angiogram
• Cystoid macular edema (complication)
• Serpiginous choroidopathy (pattern of lesion)
Ultrasonography
• Especially in cases of media opacities
Ocular tissue analysis
• Aqueous tap
• Vitreous tap
• Chorioretinal biopsy
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11. Cycloplegic mydriatics
To relieve ciliary spasm and pain
To prevent posterior synechiae and break the ones already
formed
Partly broken posterior synechiae
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12. Cycloplegic mydriatics
Shorter acting
Tropicamide eye drops (effective up to 3 hrs)
Cyclopentolate drops (up to 24 hrs)
Longer acting
Homatropine eye drops (up to 4 days)
Atropine eye drops (up to 7-14 days)
Cycloplegia relieves pain and a mobile pupil prevents posterior synechiae www.ophthalclass.blogspot.com
13. Corticosteroids – the mainstay of therapy
Depending on the site of inflammation and severity
Topical
Periocular
Systemic
Topical drops will not be effective for intermediate, posterior and
panuveitis
‘Use enough soon enough’
To always start with a higher dose and taper before stopping
To investigate before starting
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15. Complications of corticosteroids
Topical Periocular Systemic
As for topical
As for topical
Cataract Weight gain
Peptic ulcer
Ptosis
Osteoporosis
Glaucoma Diabetes
Scleral perforation
Hypertension
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16. Immunosuppressives
In corticosteroid resistant or intolerant cases
In vision threatening inflammations - as first line
Specific cases
Beh et’s syndrome
Sympathetic ophthalmitis
VKH syndrome
Necrotizing sclerouveitis
Adverse reactions can be severe and life threatening
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17. Immunosuppressives
Alkylating
Antimetabolites T-cell inhibitors
agents
Methotrexate Cyclophosphamide Cyclosporine
Azathioprine Chlorambucil Tacrolimus
Watch out for nephrotoxicity, hepatotoxicity and marrow toxicity www.ophthalclass.blogspot.com
18. Surgery in uveitis
Diagnostic
AC tap
Vitreous biopsy
Chorioretinal biopsy
Therapeutic
Cataract
Glaucoma
Retinal detachment
Vitrectomy
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20. Management of complications
Cataract surgery
If no active inflammation for at least 3 months
Perioperative steroids
Heparin surface modified IOLs
Glaucoma
Anti-glaucoma topical medication
Peripheral iridotomy / iridectomy in iris bombé
Trabeculectomy with mitomycin C or 5 fluorouracil
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21. Management of complications
Cystoid macular edema
Control of inflammation - corticosteroids
NSAIDs
Pars plana vitrectomy if persistent vitritis
Hypotony
Intensive corticosteroids and cycloplegia
Pars plana membranectomy for cyclitic membrane
Vitreous opacification
Pars plana vitrectomy
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23. Anterior uveitis
35 yr old male
Ciliary congestion, fine KPs, AC flare, posterior synechiae and
hypopyon in RE
Similar history of redness a year ago
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29. Intermediate uveitis…
Management
Lymph node biopsy
Caseating granulomatous lesions
Physician diagnosis - tuberculosis
Systemic management
ATT – fever responded within 4 days
Ocular management
On 1 week follow up, vision drop of 2 lines
Systemic corticosteroids under cover of ATT for short period (1mg/kg
body wt of prednisone, tapered and stopped within 4 weeks)
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30. Posterior uveitis
35 year old, HIV positive female
Sudden painless loss of vision RE
Ocular examination
Spill over fine KPs
CMV retinitis in the fundus
CD4 count – 50
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