Macromolecules are large organic molecules composed of smaller building blocks called monomers. There are four main types of macromolecules: carbohydrates, lipids, proteins, and nucleic acids. Carbohydrates include sugars like glucose and can be linked together into polysaccharides. Lipids are non-soluble in water and include fats and oils, storing the most energy. Proteins are made of amino acids linked by peptide bonds and perform important functions in the body. Nucleic acids like DNA and RNA are composed of nucleotides and carry genetic information.