There are two main types of optical fiber signal loss: scattering and absorption. Scattering losses include Rayleigh scattering caused by molecular irregularities and Mie scattering caused by larger defects. Absorption losses are caused by intrinsic material properties like ultraviolet and infrared absorption in silica glass, as well as extrinsic impurities introduced during manufacturing. Proper fiber design and high material purity can minimize these signal losses to enable effective optical fiber communication.