This lecture discusses computer aided drug design (CADD). CADD uses computational methods to aid in drug discovery and design. It involves identifying drug targets, generating potential drug molecule "hits" through virtual screening, and optimizing "leads" through modeling protein-ligand interactions and simulating the effects of molecular modifications. The key steps are target identification, validation of targets, lead identification through screening libraries or de novo design, lead optimization through docking simulations, and preclinical/clinical trials. CADD approaches like ligand-based, target-based, and structure-based drug design can speed up the drug development process and reduce costs compared to traditional experimental methods alone.