Lecture 2. Support and Protection
Integumentary System
Functions:

1. protective wrapping
   –
       mechanical protection against abrasion and
       puncture
   –
       effective barrier against bacteria
   –
       moisture proofing against fluid loss or gain
   –
       protect underlying cells against UV

2. regulatory function
   –
       temperature regulation
Integumentary System
Functions:

3. information getting
   –
       sensory receptors

4. excretory function

5. respiratory function

6. survival

7. behavioral interactions between individuals
Invertebrate Integument
1. Plasma membrane
  –
      unicellular protozoa
  –
      gas exchange and waste removal by simple diffusion
  –
      uptake of dissolved nutrients




        Amoeba
                                      Paramecium
Pellicle
   – thick protein coat found in other protozoa
   – offers further environmental protection
   – semi-rigid structure that transmits the force of cilia
     or flagella to the entire body as the animal moves
Invertebrate Integument
2. Epidermis
  –
      in most multicellular invertebrates
  –
      single layer of columnar epithelial cells
  –
      some invertebrates have cuticle over the epidermis
  –
      delicate and soft in molluscs and contain mucous
      glands, some of which secrete calcium carbonate of
      the shell
Mantle
  – pair of folds formed by the dorsal body wall
  – outer surface secretes shell
(nonchitinous complex
                                     of protein and lipids)

                                      (protein and chitin)




– arthropods have the most complex of invertebrate
  integuments
– for protection and skeletal support
The arthropod cuticle may be hardened by:
1. calcification – deposition of calcium carbonate in the
                   outer layers of procuticle
The arthropod cuticle may be hardened by:
2. sclerotization – protein molecules bond together with
       stabilizing cross-linkages within and between
       adjacent lamellae of the procuticle
    – formation of a highly resistant and insoluble
      protein, sclerotin
Molting of arthropods
  – epidermal cells divide by mitosis
  – epidermis secretes enzyme to digest procuticle
  – absorption of digested materials
  – new epicuticle and procuticle formed
  – new cuticle is thickened and calcified or sclerotized
Vertebrate Integument
Skin and derivatives
Vertebrate Integument
Skin and derivatives
Epidermis
  – stratified squamous epithelium
  – devoid of blood vessels
  – cells of the basal part undergo frequent mitosis
  – as outer layer of cells are displaced upward by new
    generations of cells beneath, keratinization takes
    place
  – cornified cells, highly resistant to abrasion and
    water diffusion, comprise the outermost stratum
    corneum
Dermis
  – dense connective tissue layer
  – contains blood vessels, collagenous fibers, nerves,
    pigment cells, fat cells, and fibroblasts
  – support, cushion, and nourish the epidermis
  – macrophages and lymphocytes provide the first line
    of defense
Epidermal derivatives
Dermal derivatives
Similarity of structure of integumentary derivatives




                   - all are built of similar combinations
                     of epidermal (keratinized) and
                     dermal components
Hairs
  –
      epidermal growths that function in protection
  –
      shaft, root, and follicle
  –
      sebaceous glands, arrector pili muscle, and hair
      root plexus (touch)
Hairs
• Types
   1. Underhair
      •
        Dense and soft
      •
        For insulation
   2. Guard hair
      •
        Coarse and longer
      •
        For protection against wear and to
        provide coloration
Nails
•
    plates of highly packed, keratinized cells
•
    protection, scratching, and manipulation
•
    formed by cells in nail bed called the matrix (in
    area of lunula)
•
    1 mm / week
•
    eponychium - cuticle
Skin Glands
•
     Sebaceous (oil) glands
     –
         usually connected to
         hair follicles
     –
         fats, cholesterol,
         proteins, salts, and cell
         debris
     –
         moistens hair and
         waterproofs skin
•
    Sweat (sudoriferous) glands
     –
         Eccrine sweat glands
          •   water, salt, wastes
          •   hairless regions, scattered
    over the body
          •   function is to cool the body


     –
         Apocrine sweat glands
          •   larger
          •   associated with hair follicles
          •   more viscous – fatty acids and proteins
•
    Ceruminous glands
    –
        modified sudoriferous glands
    –
        secrete cerumen (ear wax)
    –
        Cerumen protects the skin of
        the ear canal, assists in
        cleaning and lubrication, and
        provides protection from
        bacteria, fungi and insects
Mammary glands
   •
     Secrete milk
   •
     Thickening of epidermis
Animal coloration
  –
      vivid and dramatic when serving as important
      recognition marks or warning coloration
  –
      subdued or cryptic when used for camouflage
1. Structural color
  –
      produced by the physical
      structure of the surface
      tissue; tissue reflects
      certain light wavelengths
      and eliminates others
  –
      phase interference effects
      of the microscopic
      structure of feathers
                                   A. sunlight   B. camera flash
  –
      different response
      depending on the direction
      or directionality of
      illumination
2. color due to pigments
  –
      Biochromes – pigments produced by chromatophores
  –
      reflect light rays
  –
      chromatophores or pigment cells:
       •
           melanophores/melanocytes (melanin)
       •
           xanthophores (carotenoid)
       •
           iridophores (crystals of purine → silvery or
           metallic)
Skeletal System

Functions:                 Types:
  –
      support                1. Hydrostatic skeleton
                             2. Rigid skeleton
  –
      protection
  –
      movement
  –
      mineral depot
  –
      blood synthesis
34


                 1. Hydrostatic Skeleton
     •
         Functions
         –
             supports body form
         –
             provides resistance for the contraction of muscles
             to act against
     •
         Source
         –
             some organisms use their fluid-filled
             gastrovascular cavity
         –
             others use their fluid-filled coelom (body cavity)
Hydra with gastrovascular cavity
Earthworm with fluid-filled coelom
Muscular hydrostats
  –
      like hydrostatic skeletons,
      these work because they
      are composed of
      incompressible tissues that
      remain at constant volume
  –
      muscles arranged in
      complex patterns
2. Rigid Skeletons
•
    consist of rigid elements
•
    usually jointed
•
    muscle attachment
•
    2 principal types
    –
        exoskeleton
    –
        endoskeleton
•
    Exoskeleton - external skeleton
    –
        Molluscs - composed of calcium carbonate
    –
        Arthropods - composed of chitin
    –
        protection and locomotion
•
    Endoskeleton - internal skeleton
    –
        Echinoderms and vertebrates
    –
        mineralized bone and cartilage
    –
        support, protection, and reservoir of calcium and
        phosphorous
    –
        grows as the animal grows
         ü does   not limit space for internal organs
         ü supports greater   weight
Notochord
  − semirigid supportive axial
   rod of protochordates
   and all vertebrate larvae
   and embryos
  − composed of large
   vacuolated cells
   surrounded by elastic and
   fibrous sheaths
  − stiffening device

  − except in jawless
   vertebrates, surrounded
   or replaced by the back
   bone during embryonic
   development             Lancelet, Branchiostoma
Cartilage
  − major skeletal element of
   some vertebrates
  − soft, pliable tissue that
   resists compression
  − jawless vertebrates and
   elasmobranchs have
   purely cartilaginous
   skeletons




                            Lamprey
Bone
 − living tissue having significant deposits of calcium salts in the
  extracellular matrix
 − endochondral or replacement bone
   − any bone that develops in and replaces cartilage
   − i.e. long bone
 − intramembranous bone
    − any bone that develops without any associated cartilage
    − i.e. parietal and frontal bones of the face
 − cancellous or spongy bone
    − bone composed of thin intersecting lamellae, usually found
     internal to compact bone
 − compact bone
    − bone substance that is dense
Long bone
Structure of compact bone
Bone Growth and Renewal
•
    Cartilage structures in early development act as models for
    future bones
    –
        calcium salts deposited in matrix by cartilage cells and
        later by osteoblasts
    –
        endochondral ossification
•
    Osteoclasts
    –
        break down bone
    –
        remove worn cells
    –
        deposit calcium in the blood
    –
        work with osteoblasts to heal broken bones
•
    Role of hormones
    –
        somatotropin, calcitonin, parathyroid hormone
Stages of Intramembranous Ossification
Stages of Intramembranous Ossification
Stages of Intramembranous Ossification
Stages of Intramembranous Ossification
Stages of Endochondral Ossification                                 Secondary            Articular
                                                                     ossification         cartilage
                                                                     center
                                                          Epiphyseal                      Spongy
                            Deteriorating                 blood vessel                    bone
         Hyaline            cartilage matrix
         cartilage
                                     Spongy                                               Epiphyseal
                                     bone                                                 plate
         Primary
                                     formation                                            cartilage
         ossification                                          Medullary
         center                                                cavity


          Bone                       Blood
          collar                     vessel of
                                     periosteal
                                     bud
1 Formation
  of bone            2 Cavitation
  collar                of the              3 Invasion of
  around                hyaline                internal cavities    4 Formation of the
  hyaline               cartilage              by the                    medullary cavity as          5 Ossification of the
  cartilage             within the             periosteal bud            ossification continues;        epiphyses; when
  model.                cartilage              and spongy                appearance of                  completed, hyaline
                        model.                 bone formation.           secondary ossification         cartilage remains
                                                                         centers in the                 only in the
                                                                         epiphyses in                   epiphyseal plates
                                                                         preparation for stage 5.       and articular
                                                                                                        cartilages
Plan of the vertebrate skeleton
•
  2 main divisions
  –
      axial skeleton (skull, vertebral column, sternum,
      and ribs)
  –
      appendicular skeleton (limbs, fins, wings, pectoral
      and pelvic girdles)
Human Skeletal System
•
    Functions
    –
        supports and protects the body
    –
        permits movement
    –
        provides resistive foundation for muscles to act
        against
•
    Bones store calcium and phosphate ions
•
    Certain bones produce red blood cells
55
     The Human Skeleton
56


     The Skull
Vertebral Column
•
    Vertebral column
    –
        supports the head and trunk
    –
        protects the spinal cord and roots of spinal nerves

•
    Segments (from superior to inferior)
    –
        cervical - neck
    –
        thoracic - chest
    –
        lumbar - small of back
    –
        sacral – sacrum/pelvic
# of        Body       Abbreviatio
Term
           Vertebrae   Area       n
Cervical   7           Neck       C1 – C7
Thoracic   12          Chest      T1 – T12
Lumbar     5 or 6      Low Back   L1 – L5
Sacrum     5 (fused)   Pelvis     S1 – S5
Coccyx     3           Tailbone   None
Rib Cage
•
    Protects the heart and lungs, and assists breathing
•
    Support by the thoracic vertebrae
    –
        Twelve pairs of ribs
         •   true ribs
              –
                  connect directly to sternum
              –
                  seven pairs
         •   “false” ribs
              –
                  do not connect directly to sternum
              –
                  five pairs
60
     The Rib Cage
The Appendicular Skeleton
•
    Consists of
    –
        the bones within the pectoral and pelvic girdles
    –
        the attached limbs

•
    Pectoral girdle – bones of the shoulder
    –
        anterior
    –
        supports the arms and hands

•
    Pelvic girdle - bones of the pelvis
    –
        posterior
    –
        supports the legs and feet
Bones of the Pectoral
        Girdle,
the Arm, and the Hand
Bones of the Pelvic
       Girdle,
the Leg, and the Foot
Classification of Joints
• Fibrous Joints (synarthroses)
  – immovable
  – between cranial bones, tibia & fibula, radius & ulna
Classification of Joints
• Cartilaginous Joints (amphiarthroses)
  – slightly movable
  – between vertebrae
Classification of Joints
• Synovial Joints (diarthroses)
                                  – freely movable
                                  – bones
                                    separated by a
                                    cavity
                                  – ball and
                                    socket, hinge
                                    joints

Lecture 2 support and protection 2nd sem 2008-2009

  • 1.
    Lecture 2. Supportand Protection
  • 2.
    Integumentary System Functions: 1. protectivewrapping – mechanical protection against abrasion and puncture – effective barrier against bacteria – moisture proofing against fluid loss or gain – protect underlying cells against UV 2. regulatory function – temperature regulation
  • 3.
    Integumentary System Functions: 3. informationgetting – sensory receptors 4. excretory function 5. respiratory function 6. survival 7. behavioral interactions between individuals
  • 4.
    Invertebrate Integument 1. Plasmamembrane – unicellular protozoa – gas exchange and waste removal by simple diffusion – uptake of dissolved nutrients Amoeba Paramecium
  • 5.
    Pellicle – thick protein coat found in other protozoa – offers further environmental protection – semi-rigid structure that transmits the force of cilia or flagella to the entire body as the animal moves
  • 6.
    Invertebrate Integument 2. Epidermis – in most multicellular invertebrates – single layer of columnar epithelial cells – some invertebrates have cuticle over the epidermis – delicate and soft in molluscs and contain mucous glands, some of which secrete calcium carbonate of the shell
  • 7.
    Mantle –pair of folds formed by the dorsal body wall – outer surface secretes shell
  • 8.
    (nonchitinous complex of protein and lipids) (protein and chitin) – arthropods have the most complex of invertebrate integuments – for protection and skeletal support
  • 9.
    The arthropod cuticlemay be hardened by: 1. calcification – deposition of calcium carbonate in the outer layers of procuticle
  • 10.
    The arthropod cuticlemay be hardened by: 2. sclerotization – protein molecules bond together with stabilizing cross-linkages within and between adjacent lamellae of the procuticle – formation of a highly resistant and insoluble protein, sclerotin
  • 11.
    Molting of arthropods – epidermal cells divide by mitosis – epidermis secretes enzyme to digest procuticle – absorption of digested materials – new epicuticle and procuticle formed – new cuticle is thickened and calcified or sclerotized
  • 12.
  • 13.
  • 14.
    Epidermis –stratified squamous epithelium – devoid of blood vessels – cells of the basal part undergo frequent mitosis – as outer layer of cells are displaced upward by new generations of cells beneath, keratinization takes place – cornified cells, highly resistant to abrasion and water diffusion, comprise the outermost stratum corneum
  • 16.
    Dermis –dense connective tissue layer – contains blood vessels, collagenous fibers, nerves, pigment cells, fat cells, and fibroblasts – support, cushion, and nourish the epidermis – macrophages and lymphocytes provide the first line of defense
  • 17.
  • 18.
  • 20.
    Similarity of structureof integumentary derivatives - all are built of similar combinations of epidermal (keratinized) and dermal components
  • 22.
    Hairs – epidermal growths that function in protection – shaft, root, and follicle – sebaceous glands, arrector pili muscle, and hair root plexus (touch)
  • 23.
    Hairs • Types 1. Underhair • Dense and soft • For insulation 2. Guard hair • Coarse and longer • For protection against wear and to provide coloration
  • 24.
    Nails • plates of highly packed, keratinized cells • protection, scratching, and manipulation • formed by cells in nail bed called the matrix (in area of lunula) • 1 mm / week • eponychium - cuticle
  • 25.
    Skin Glands • Sebaceous (oil) glands – usually connected to hair follicles – fats, cholesterol, proteins, salts, and cell debris – moistens hair and waterproofs skin
  • 26.
    Sweat (sudoriferous) glands – Eccrine sweat glands • water, salt, wastes • hairless regions, scattered over the body • function is to cool the body – Apocrine sweat glands • larger • associated with hair follicles • more viscous – fatty acids and proteins
  • 27.
    Ceruminous glands – modified sudoriferous glands – secrete cerumen (ear wax) – Cerumen protects the skin of the ear canal, assists in cleaning and lubrication, and provides protection from bacteria, fungi and insects
  • 28.
    Mammary glands • Secrete milk • Thickening of epidermis
  • 29.
    Animal coloration – vivid and dramatic when serving as important recognition marks or warning coloration – subdued or cryptic when used for camouflage
  • 30.
    1. Structural color – produced by the physical structure of the surface tissue; tissue reflects certain light wavelengths and eliminates others – phase interference effects of the microscopic structure of feathers A. sunlight B. camera flash – different response depending on the direction or directionality of illumination
  • 31.
    2. color dueto pigments – Biochromes – pigments produced by chromatophores – reflect light rays – chromatophores or pigment cells: • melanophores/melanocytes (melanin) • xanthophores (carotenoid) • iridophores (crystals of purine → silvery or metallic)
  • 33.
    Skeletal System Functions: Types: – support 1. Hydrostatic skeleton 2. Rigid skeleton – protection – movement – mineral depot – blood synthesis
  • 34.
    34 1. Hydrostatic Skeleton • Functions – supports body form – provides resistance for the contraction of muscles to act against • Source – some organisms use their fluid-filled gastrovascular cavity – others use their fluid-filled coelom (body cavity)
  • 35.
  • 36.
  • 38.
    Muscular hydrostats – like hydrostatic skeletons, these work because they are composed of incompressible tissues that remain at constant volume – muscles arranged in complex patterns
  • 39.
    2. Rigid Skeletons • consist of rigid elements • usually jointed • muscle attachment • 2 principal types – exoskeleton – endoskeleton
  • 40.
    Exoskeleton - external skeleton – Molluscs - composed of calcium carbonate – Arthropods - composed of chitin – protection and locomotion
  • 41.
    Endoskeleton - internal skeleton – Echinoderms and vertebrates – mineralized bone and cartilage – support, protection, and reservoir of calcium and phosphorous – grows as the animal grows ü does not limit space for internal organs ü supports greater weight
  • 42.
    Notochord −semirigid supportive axial rod of protochordates and all vertebrate larvae and embryos − composed of large vacuolated cells surrounded by elastic and fibrous sheaths − stiffening device − except in jawless vertebrates, surrounded or replaced by the back bone during embryonic development Lancelet, Branchiostoma
  • 43.
    Cartilage −major skeletal element of some vertebrates − soft, pliable tissue that resists compression − jawless vertebrates and elasmobranchs have purely cartilaginous skeletons Lamprey
  • 44.
    Bone − livingtissue having significant deposits of calcium salts in the extracellular matrix − endochondral or replacement bone − any bone that develops in and replaces cartilage − i.e. long bone − intramembranous bone − any bone that develops without any associated cartilage − i.e. parietal and frontal bones of the face − cancellous or spongy bone − bone composed of thin intersecting lamellae, usually found internal to compact bone − compact bone − bone substance that is dense
  • 45.
  • 46.
  • 47.
    Bone Growth andRenewal • Cartilage structures in early development act as models for future bones – calcium salts deposited in matrix by cartilage cells and later by osteoblasts – endochondral ossification • Osteoclasts – break down bone – remove worn cells – deposit calcium in the blood – work with osteoblasts to heal broken bones • Role of hormones – somatotropin, calcitonin, parathyroid hormone
  • 48.
  • 49.
  • 50.
  • 51.
  • 52.
    Stages of EndochondralOssification Secondary Articular ossification cartilage center Epiphyseal Spongy Deteriorating blood vessel bone Hyaline cartilage matrix cartilage Spongy Epiphyseal bone plate Primary formation cartilage ossification Medullary center cavity Bone Blood collar vessel of periosteal bud 1 Formation of bone 2 Cavitation collar of the 3 Invasion of around hyaline internal cavities 4 Formation of the hyaline cartilage by the medullary cavity as 5 Ossification of the cartilage within the periosteal bud ossification continues; epiphyses; when model. cartilage and spongy appearance of completed, hyaline model. bone formation. secondary ossification cartilage remains centers in the only in the epiphyses in epiphyseal plates preparation for stage 5. and articular cartilages
  • 53.
    Plan of thevertebrate skeleton • 2 main divisions – axial skeleton (skull, vertebral column, sternum, and ribs) – appendicular skeleton (limbs, fins, wings, pectoral and pelvic girdles)
  • 54.
    Human Skeletal System • Functions – supports and protects the body – permits movement – provides resistive foundation for muscles to act against • Bones store calcium and phosphate ions • Certain bones produce red blood cells
  • 55.
    55 The Human Skeleton
  • 56.
    56 The Skull
  • 57.
    Vertebral Column • Vertebral column – supports the head and trunk – protects the spinal cord and roots of spinal nerves • Segments (from superior to inferior) – cervical - neck – thoracic - chest – lumbar - small of back – sacral – sacrum/pelvic
  • 58.
    # of Body Abbreviatio Term Vertebrae Area n Cervical 7 Neck C1 – C7 Thoracic 12 Chest T1 – T12 Lumbar 5 or 6 Low Back L1 – L5 Sacrum 5 (fused) Pelvis S1 – S5 Coccyx 3 Tailbone None
  • 59.
    Rib Cage • Protects the heart and lungs, and assists breathing • Support by the thoracic vertebrae – Twelve pairs of ribs • true ribs – connect directly to sternum – seven pairs • “false” ribs – do not connect directly to sternum – five pairs
  • 60.
    60 The Rib Cage
  • 61.
    The Appendicular Skeleton • Consists of – the bones within the pectoral and pelvic girdles – the attached limbs • Pectoral girdle – bones of the shoulder – anterior – supports the arms and hands • Pelvic girdle - bones of the pelvis – posterior – supports the legs and feet
  • 62.
    Bones of thePectoral Girdle, the Arm, and the Hand
  • 63.
    Bones of thePelvic Girdle, the Leg, and the Foot
  • 64.
    Classification of Joints •Fibrous Joints (synarthroses) – immovable – between cranial bones, tibia & fibula, radius & ulna
  • 65.
    Classification of Joints •Cartilaginous Joints (amphiarthroses) – slightly movable – between vertebrae
  • 66.
    Classification of Joints •Synovial Joints (diarthroses) – freely movable – bones separated by a cavity – ball and socket, hinge joints