Regional anesthesia involves administering local anesthetics near nerves to block pain signals from specific parts of the body. There are several types including neuraxial blocks like epidurals and spinals that involve the spinal canal, and peripheral nerve blocks that target individual nerves. Regional anesthesia has advantages like reduced blood loss and postoperative complications compared to general anesthesia, though placement can be difficult and side effects like hypotension are possible. Proper technique and monitoring are needed to avoid complications.