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Pre Anaesthesia
Evaluation
Presented by : Dr Sushma
Moderator : Dr Harshal
Consultant Anaesthetist , KIMS
PREOP EVALUATION
• A process of clinical assessment that precedes
the delivery of anesthesia for surgical and non
surgical procedures.
• Guides the anesthetic plan
An opportunity for the anesthesiologist to:
• Describe the proposed anesthetic plan
• Psychological support to the pt
• Obtain informed consent
Preop Evaluation
• Inadequate preoperative planning and
incomplete patient preparation are commonly
associated with anesthetic complications.
Purpose of effective pre op evaluation
• To identify those few patients whose
outcomes will be improved by
implementation of a specific medical
treatment eg: 60 y/o patient scheduled for
elective total hip arthroplasty who also has
unstable angina from left main coronary
artery disease would more likely survive if
coronary artery bypass grafting is performed
before the elective procedure
Purpose of effective pre op evaluation
• To identify patients whose condition is so
poor that the proposed surgery might only
hasten death without improving the quality
of life . eg, a patient with severe chronic lung
disease, end-stage kidney failure, liver failure,
and heart failure likely would not survive to
derive benefit from an 8-hour, complex,
multilevel spinal fusion with instrumentation.
Purpose of effective pre op evaluation
• To identify patients with specific
characteristics that likely will influence the
proposed anesthetic plan eg: the anesthetic
plan may need to be reassessed for a patient
whose trachea appears difficult to intubate,
one with a family history of malignant
hyperthermia, or one with an infection near
where a proposed regional anesthetic would
be administered.
• To provide the patient with an estimate of
anesthetic risk . However, the anesthesiologist
should not be expected to provide the risk-
versus-benefit discussion for the proposed
procedure(responsibility of the surgeon)
Elements of the Preoperative History
Patients presenting for elective surgery and
anesthesia typically require a focused
preoperative medical history emphasizing
• Cardiac
• Pulmonary function
• Kidney disease
• Endocrine and metabolic diseases
• Musculoskeletal
• Anatomic issues relevant to airway management
and regional anesthesia
• Responses and reactions to previous anesthetics.
History Taking
• Demographic details
• Present medical history (Presenting complaint/
History of presenting complaint)
• Past medical history
• Surgical history / Previous anesthetic history
• Drug history(allergies/present medications)
• Family history
• Social history
Demographic Details
Date & time of examination
Patient’s name
Age
Sex
Weight
Past Medical History
Goals
• To ensure that the patient is in the optimal
condition.
• Patients with unstable symptoms should be
postponed for optimization prior to elective
surgery.
• Anesthetic drugs and techniques have profound
effects on human physiology
• Hence, focused review of all major organ system
should be done prior to elective surgery.
Cardiovascular Issues
Preoperative cardiac assessment:
• Whether the patient’s condition need to be
improved prior to the sx
• Need for any further cardiac evaluation prior
to the surgery
CVS
Symptoms of the following problems
Active Cardiac Conditions
• Unstable coronary syndromes
• Unstable or severe angina
• Recent MI
• Decompensated HF
• Significant arrhythmias
• Severe valvular disease
Specific enquiries must be made
about
Coronary Artery Disease
Determine
• Type
• Severity
• Functional limitation
RISK FACTORS OF CAD
• Age over 45
• Obesity
• Angina
• Prior MI or CHF
• Dysrrhythmias
Angina
• Chest pain at rest/with mild exercise, Freq and
duration
• Incidence , precipitating factors, duration of
use of anti-anginal medications, e.g. Glyceryl
trinitrate (GTN) oral or sublingual )
• Stable angina – proceed wd sx
• Unstable angina- em sx only
Ischemic Heart Disease
There is a high incidence of both silent MI and
myocardial ischaemia in diabetics.
High risk :
• MI wd in past 6m
• CHF
Extremely high risk
• Signs: orthopnea sweating palpitations night
coughing
H/o previous myocardial infarction and subsequent
symptoms indicating heart failure /MI are at a
greater risk of perioperative reinfarction .
• Elective surgery postponed until at least 6
months after the event
Valvular Heart Disease
• Prosthetic valves - on anticoagulants
• Acs need to be stopped or changed (bridging
therapy)prior to surgery
• Antibiotic prophylaxis
Heart Failure
• Symptoms : fatigue ,palpitations ,sweating
,dyspnea ,chest pain, syncope
• worsened by the depressant effects of
anaesthetics impairing the perfusion of vital
organs
HYPERTENSION
HYPERTENSION
• How long
• Tx
• Compliance with tx
• How well it is controlled
Severe HTN
• Systolic >195
• Diastolic>100
• Delay non urgent sx
• Obtain approp consultation and Rx
Mild HTN
• Systolic <165
• diastolic<100
• Evaluate other risks
• Proceed with caution
• Obtain approp followup
HYPERTENSION
• Untreated and poorly controlled HTN may
lead to exaggerated cardiovascular responses
during anesthesia.
• Both HTN and hypotension can be
precipitated, which increase the incidence of
both mycardial and cereberal ischaemia.
HTN
• Controversy regarding delay or cancel a sx in a
patient with untreated or inadequately treated
hypertension.
• In patients with blood pressure above 180/100
mm hg , in the absence of end organ changes,
such as renal insufficency , LVH with strain the
benefits of optimizing BP must be weighed
against the risk of delaying surgery.
REVISED CARDIAC RISK INDEX (cardiac pts undergoing
elective major non cardiac procedures)
Surgical Risk Stratification (for cardiac pt
undergoing non cardiac sx)
Clinical Predictors Of Increased Perioperative
CVS Risk(MI,CHF,death)
MAJOR
• Unstable coronary syndromes
• Recent MI with evidence ischaemic risk by clinical
symptoms or noninvasive study
• Unstable or severe angina
• Decompensated CHF
• Significant arrythmias - High grade AV block,
Symptomatic ventricular aarythmias in the presence of
underlying heart disease, Supraventricular arrythmias
with uncontrolled ventricular rate.
• Severe valvular disease.
Clinical Predictors Of Increased
Perioperative CVS Risk
INTERMEDIATE
• Mild angina
• Prior MI by history or pathological Q waves
• Compensated or prior CHF
• Diabetes mellitus
Clinical Predictors Of Increased
Perioperative Cvs Risk
MINOR
• Advanced age
• Abnormal ECG (LVH,LBBB, ST-T abnormalities)
• Arrhythmias (e.g- AF)
• Low functional capacity (e.g- inability to climb
one flight of stairs )
• History of stroke
• Uncontrolled systemic HTN
Functional Capacity – (MET )Metabolic
equivalents
• A unit of functional activity
• Expressed as a multiple of current metabolic
rate to the resting metabolic rate
• It is the rate of energy consumption where
1met is the basic metabolic consumption
• 1met =3.5mloxygen/kg/min(resting metab
consumption)
• Lowest met =0.9(sleeping)
METS
• To withstand the stress of sx pts should
achieve 4mets of functional capacity
• Perioperative cardiac and long-term risks are
elevated in patients unable to obtain 4-MET
demand
• Able to climb 2flights of stairs without getting
tired indicates good reserve - FC>4mets
METS
METS
CENTRAL NERVOUS SYSTEM
Problems
• Ischemia/vasospasm
• Embolism/thrombosis
• Tumor
• Aneurysm/haemorrhage
• Seizures - well controlled or not
• stroke
• Correlate h/o with physical findings
CNS
Signs and symptoms
• Nausea /vomiting
• Vertigo
• Headache /vision disturbances
• Htn/brady
• Focal sensory/motor defecits
• Slurred speech
• Confusion/disorientation
• Coma
Peripheral Neuropathy
Signs and symptoms
• Weakness or loss of function
• Tingling/numbness
• Cold/pale extremities
• Diminished reflexes
Peripheral Neuropathy
Causes:
• Autonomic dysfunction
• Dm
• Drug induced neuropathy
• Nerve compression
Get neuro consultation for new symptoms
Evaluation prior to regional anaesthesia
HEPATIC SYSTEM
• H/o jaundice/hepatitis
Viral hepatitis
• Easily transmitted
• Nonsp symptoms like fatigue, malaise, vague
abd pain
• Symptoms of hepatitis: spider navi , ascites,
generalised tremor ,confusion /disorientation
HEPATIC SYSTEM
Coexsisting diseases
• Obesity
• Fatty liver
• Alcohol abuse
• Multiple blood transfusions
• Recreational drug use
• Coagulation disorders
RENAL SYSTEM
• Probs wd urination
• Chronic cystitis
• Prostatitis
• Renal calculi
• ARF/CRF
• Electrolyte abnormalities
• Hypervololemia HTN Hyperkalemia
RENAL
ARF/CRF
• Get accurate h/o dialysis schedule , last
dialysis, RFT& electrolytes after dialysis
Chronic renal failure
• Anaemia
• Electrolyte abnormalities
• Altered drug excretion restricts the choice of
anaesthetic agents
RESPIRATORY SYSTEM
• Detailed History of recent URTI, sorethroat ,
productive cough, dyspnea(exertion/rest),
allergies(hay fever),sleep apnea
• Acute disease:
URTI/Asthma/Bronchitis/Pneumonia
• Chronic disease: COPD/TB
• Asthma: duration ,last episode, hospitalisation ,tx
(bronchodilators)
• COPD-productive cough , smoking packs perday
RESPIRATORY SYSTEM
Pulmonary complications occurs more frequently than
cardiac complications (5-10% incidence )
• Perioperative complications includes:
1. Aspiration
2. Atelectasis
3. Pnuemonia
4. Bronchitis
5. Bronchospasm
6. Hypoxemia
7. AE COPD
8. Respiratiory failure requiring mechanical ventilation
Cases where there is markedly increased
risk of pulmonary complications
• ASA class 3 and class 4 patients ( compared to class 1)
• Cigarette smoking
• Longer surgeries(>4 h)
• Certain types of surgeries:
 Abdominal
 Thoracic
 Aortic aneurysm
 Head and neck
 Emergency surgery
• General anesthesia (compared with cases in which GA was
not used)
Efforts required for prevention of
pulmonary complications
• Cessation of smoking prior to surgery
• Lung expansion techniques (eg, incentive
spirometry) after surgery in patients at risk.
• Patients with asthma, have a greater risk for
bronchospasm during airway manipulation.
• Appropriate use of analgesia and monitoring
are key strategies for avoiding postoperative
respiratory depression in patients with
obstructive sleep apnea.
GASTRO INSTESTINAL SYSTEM
• Nutritional status
• Obese/anorexic
• Wt gain/loss
• Gastric reflux
• Evaluate aspiration risk
GASTRO INTESTINAL SYSTEM
The risk of aspiration is increased in certain groups
of patients
• Morbidly Obese
• Pregnant women in the second and third
trimesters
• Hiatus hernia
• Full stomach (em sx / trauma)
• Serious gastroesophageal reflux disease (GERD).
Severe GERD:
Treat patients with consistent symptoms
(multiple times per week) with
• Medications (eg, nonparticulate antacids such
as sodium citrate)
• Techniques (eg, tracheal intubation)
Pharmacological Agents to Reduce the
risk of Pulmonary Aspiration
• Histamine – 2 Receptor Antagonist : block the
ability of histamine to induce secretion of gastric
fluid with high hydrogen concentrations
e.g. Cimetidine, Ranitidine, Famotidine
• Antacids – neutralize the acid in gastric content
• Proton pump inhibitors: supress gastric acid
secretion by binding proton pump of the parietal
cell
• Prokinetic agents : Metoclopramide (Dopamine
antagonist)
COAGULATION ISSUES
• How to manage patients who are taking
warfarin on a long-term basis(anticoagulants)
• How to manage patients who are taking
clopidogrel and related agents(antiplatelets)
• How to safely provide regional anesthesia to
patients who either are receiving long-term
anticoagulation therapy or who will receive
anticoagulation perioperatively.
ANTICOAGULANTS
Patients at high risk for thrombosis:
Mechanical heart valve implants
 Atrial fibrillation
Prior thromboembolic stroke
Bridging Therapy
ANTICOAGULANTS
• Patients at lower risk for thrombosis may have
warfarin discontinued and then reinitiated
after successful surgery.
• Decisions regarding bridging therapy often
require consultation with the physician who
initiated the warfarin therapy
ANTIPLATELETS
Aspirin
• Consider selectively continuing aspirin in patients
where the risk of cardiac events is felt to exceed
the risk of major bleeding.
• If reversal of platelet inhibition is necessary, stop
aspirin at least 3 days before surgery.
• Do not discontinue aspirin in patients who have
drug eluting coronary stents until they have
completed 12 months of dual anti platelet
therapy.
ANTIPLATELETS
Thienopyridines (clopidogrel and ticlopidine)
• Cataract Surgery –no need to stop
• If reversal of platelet inhibition is necessary, then
clopidogrel must be stopped 7 days before &
Ticlopidine – 14 days before surgery
• Do not discontinue them in Pts who have drug
eluting stents before 1 year
Endocrine And Metabolic Issues
• Blood glucose measurement on the morning
of elective surgery
• Adequacy of longterm blood glucose control -
Hba1c .
• Abnormally elevated Hba1c - referral to a
diabetology service for education ,diet
modification and medications to improve
metabolic control may be beneficial.
Endocrine And Metabolic Issues
• Elective surgery should be delayed in patients
presenting with marked hyperglycemia
• Rearranging the order of scheduled cases to
allow insulin infusion to bring the blood
glucose concentration closer to the normal
range before surgery begins .
Endocrine And Metabolic Issues
Type1 IDDM
End organ disease is common
• Retinopathy
• Nephropathy
• Autonomic dysfunction
T2- NIDDM
Endocrine And Metabolic Issues
Diabetes patients have an increased incidence of
• Ischaemic heart disease
• Renal dysfunction
• Autonomic and peripheral neuropathy
• Intra- and postoperative complications
Dm - goals of Mx
• Maintain blood glucose 100-250mg/dl
• Provide adequate fluid volume
Endocrine And Metabolic Issues
• Hyperthyroid: excessive t3t4 secretion; low
TSH
• Signs and symps: hypermetab exophthalmous
tx propylthiouracil betablockers
• Hypothyroid; low t3t4 ; high TSH
• Signs and symptoms: low metabolism large
tongue
• Tx eltroxine
Endocrine And Metabolic Issues
Hyperparathyroidism:
• Hypercalcemia
• Increased bone resorption
• Reduced renal excretion
• Diagnosis; high sr calcium high pth
Endocrine And Metabolic Issues
Pheochromocytoma:
• Tumor of chromaffin tissue
• Inc production & release of epinephrine &
norepi
• S&S: intermittent HTN, headache, sweating,
tachy
• Diagnosis: inc sr epi , nor epi / Inc urine
vinylmandelic acid & metanephrine
Endocrine And Metabolic Issues
Carcinoid tumors
• Slow growing gi tumors
• Release vasoactive amines & polypeptides
5hydroxytryptamine
• Diarrhoea
• Abd cramps
• Respi distress/bronchospasm
• HTN
Histamine abd bradykinin release
• Paroxysnal hypotension
• Cutaneous flushing
• Bronchospasm
Endocrine And Metabolic Issues
Adrenocortical dysfunction – cushing syndrome
• Tx- correct fluid vol status /electrolyte
abnorm/ steroids
HEMATOLOGIC SYSTEM
Anemia
• Hb for o2 delivery
• Causes acute/chronic anemia
• Any benefit from delay of sx
• Acute bl loss-poorly tolerated
MUSCULOSKLETAL SYSTEM
Rheumatoid arthritis
• Duration, tx h/o - aspirin /nsaids/ steroids
• Chronic anemia
• Severely limited movement of their joints makes
positioning for surgery and airway maintenance
difficult.
• Tendency for dislocation of atalnto-occiptal joint
• Osteoarthritis
• Muscular dystrophies
MUSCULOSKLETAL SYSTEM
Neuromuscular disorders
• Care with muscle relaxants
• Coexisting heart disease
• Restrictive pulmonary disease
OBESITY
Determine Ideal bwt and BODY MASS INDEX
Ideal bwt (kgs):
• Broca Index = ht(cms)-105 women
ht(CMS) -100 men
BMI=Wt(kg)/Ht(m2)
Obesity Classification
OBESITY
MORBID OBESITY
Obstructive sleep apnea
• OSA is episodic upper airway narrowing during sleep.
• During sleep, the activity of the upper airway dilator
muscles decreases in a sleep-stage-dependent manner
• This leads to narrowing of the upper airway, loud
snoring, and reduction in airflow
• Can either be partial (a hypopnoea), or complete (an
apnoea).
• Apnoea Hypopnoea Index (AHI)
The total number of apnoeas and hypopnoeas per hour
of sleep
Used to describe the severity of OSA
Obstructive sleep apnea
• OSA severity -AHI
No OSA- AHI < 5/h,
Mild OSA - AHI 5–15/h,
Moderate OSA- AHI 15–30/h
Severe OSA- AHI > 30/h
• Gold standard - Polysomnography or multi-
channel respiratory polygraphy (“sleep study”)
• Questionnaires to assess OSA risk - to screen for
OSA and to assess the prevalence of OSA
STOP BANG questionarre -Screening tool
for OSA
FAMILY HISTORY
• Inherited conditions in the family
• History of prolonged apnoea , unexplained
death
Surgical History & Previous
Anaesthesia Exposure
Difficulties with previous anaesthetics
• Procedure difficulties
• Nausea
• Vomiting
• Dreams
• Awareness
• Postoperative jaundice
Surgical History & Previous
Anaesthesia Exposure
History of difficulty with venous access
• Thrombosis of vein
• Look for tattooing
DRUG HISTORY AND ALLERGIES
• Identify all medications
• Prescribed/self-administered
• Allergies to- drugs /topical preparations
(e.g.iodine)/adhesive dressings/ food
SOCIAL HISTORY
Alcohol : duration / frequency
• Alcohol induction of liver enzymes
• Tolerance
Smoking: number of cigarettes /amount of tobacco
• Nicotine stimulates the sympathetic nervous
system causing tachycardia ,hypertension
,coronary artery narrowing, hyperactive airways
• Look for withdrawal symptoms
Preparation For Anesthesia
• Continuing current medications/ treatment of
coexisting diseases
• Responsibility of the anesthesiologist to
instruct patients regarding which medications
to continue and which to hold preoperatively
Instruct Patients to take the medications
with small sips of water, even if fasting!
Medications to be Continued on the day of Surgery
• Antihypertensives except ACEI is and ARBs
• Cardiac medications e.g beta- blockers, digoxin ,antianginal
• Antidepressants, anxiolytics and other psychiatric medications
• Antiparkinson drugs
• Thyroid medications
• Birth control pills
• Eye drops
• Heartburn or reflux medications
• Narcotics
• Anticonvulsants
• Asthma medications
• Steroids
• Statins
Medications to be discontinued
• Topical medications e.g creams and ointment
• Oral hypoglycemic agents -on the day of sx
• Insulin -on the day of sx
• Diuretics (except Thiazides for bp or severe HF) -
on the day of sx
• Sildenafil(similar drugs )-24 hrs before Sx.
• NSAIDS –48 hrs before Sx.
• Warfarin ( Coumadin) 4 days before Sx
• Anticoagulants/antiplatelets
ASRA GUIDELINES
Summary
The anesthesiologist who takes the time to
adequately prepare the patient medically and
psychologically for anesthesia and surgery will
find that their job of caring for the patient
intraoperatively becomes easier, and they are
more likely to have a positive outcome as well
as a satisfied patient.
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Pre anaesthesia checkup-history new.pptx

  • 1. Pre Anaesthesia Evaluation Presented by : Dr Sushma Moderator : Dr Harshal Consultant Anaesthetist , KIMS
  • 2. PREOP EVALUATION • A process of clinical assessment that precedes the delivery of anesthesia for surgical and non surgical procedures. • Guides the anesthetic plan An opportunity for the anesthesiologist to: • Describe the proposed anesthetic plan • Psychological support to the pt • Obtain informed consent
  • 3. Preop Evaluation • Inadequate preoperative planning and incomplete patient preparation are commonly associated with anesthetic complications.
  • 4. Purpose of effective pre op evaluation • To identify those few patients whose outcomes will be improved by implementation of a specific medical treatment eg: 60 y/o patient scheduled for elective total hip arthroplasty who also has unstable angina from left main coronary artery disease would more likely survive if coronary artery bypass grafting is performed before the elective procedure
  • 5. Purpose of effective pre op evaluation • To identify patients whose condition is so poor that the proposed surgery might only hasten death without improving the quality of life . eg, a patient with severe chronic lung disease, end-stage kidney failure, liver failure, and heart failure likely would not survive to derive benefit from an 8-hour, complex, multilevel spinal fusion with instrumentation.
  • 6. Purpose of effective pre op evaluation • To identify patients with specific characteristics that likely will influence the proposed anesthetic plan eg: the anesthetic plan may need to be reassessed for a patient whose trachea appears difficult to intubate, one with a family history of malignant hyperthermia, or one with an infection near where a proposed regional anesthetic would be administered.
  • 7. • To provide the patient with an estimate of anesthetic risk . However, the anesthesiologist should not be expected to provide the risk- versus-benefit discussion for the proposed procedure(responsibility of the surgeon)
  • 8. Elements of the Preoperative History Patients presenting for elective surgery and anesthesia typically require a focused preoperative medical history emphasizing • Cardiac • Pulmonary function • Kidney disease • Endocrine and metabolic diseases • Musculoskeletal • Anatomic issues relevant to airway management and regional anesthesia • Responses and reactions to previous anesthetics.
  • 9.
  • 10. History Taking • Demographic details • Present medical history (Presenting complaint/ History of presenting complaint) • Past medical history • Surgical history / Previous anesthetic history • Drug history(allergies/present medications) • Family history • Social history
  • 11. Demographic Details Date & time of examination Patient’s name Age Sex Weight
  • 13. Goals • To ensure that the patient is in the optimal condition. • Patients with unstable symptoms should be postponed for optimization prior to elective surgery. • Anesthetic drugs and techniques have profound effects on human physiology • Hence, focused review of all major organ system should be done prior to elective surgery.
  • 14. Cardiovascular Issues Preoperative cardiac assessment: • Whether the patient’s condition need to be improved prior to the sx • Need for any further cardiac evaluation prior to the surgery
  • 15. CVS Symptoms of the following problems Active Cardiac Conditions • Unstable coronary syndromes • Unstable or severe angina • Recent MI • Decompensated HF • Significant arrhythmias • Severe valvular disease
  • 16. Specific enquiries must be made about Coronary Artery Disease Determine • Type • Severity • Functional limitation
  • 17. RISK FACTORS OF CAD • Age over 45 • Obesity • Angina • Prior MI or CHF • Dysrrhythmias
  • 18. Angina • Chest pain at rest/with mild exercise, Freq and duration • Incidence , precipitating factors, duration of use of anti-anginal medications, e.g. Glyceryl trinitrate (GTN) oral or sublingual ) • Stable angina – proceed wd sx • Unstable angina- em sx only
  • 19. Ischemic Heart Disease There is a high incidence of both silent MI and myocardial ischaemia in diabetics. High risk : • MI wd in past 6m • CHF Extremely high risk • Signs: orthopnea sweating palpitations night coughing
  • 20. H/o previous myocardial infarction and subsequent symptoms indicating heart failure /MI are at a greater risk of perioperative reinfarction . • Elective surgery postponed until at least 6 months after the event
  • 21. Valvular Heart Disease • Prosthetic valves - on anticoagulants • Acs need to be stopped or changed (bridging therapy)prior to surgery • Antibiotic prophylaxis Heart Failure • Symptoms : fatigue ,palpitations ,sweating ,dyspnea ,chest pain, syncope • worsened by the depressant effects of anaesthetics impairing the perfusion of vital organs
  • 22.
  • 24. HYPERTENSION • How long • Tx • Compliance with tx • How well it is controlled
  • 25. Severe HTN • Systolic >195 • Diastolic>100 • Delay non urgent sx • Obtain approp consultation and Rx Mild HTN • Systolic <165 • diastolic<100 • Evaluate other risks • Proceed with caution • Obtain approp followup
  • 26. HYPERTENSION • Untreated and poorly controlled HTN may lead to exaggerated cardiovascular responses during anesthesia. • Both HTN and hypotension can be precipitated, which increase the incidence of both mycardial and cereberal ischaemia.
  • 27. HTN • Controversy regarding delay or cancel a sx in a patient with untreated or inadequately treated hypertension. • In patients with blood pressure above 180/100 mm hg , in the absence of end organ changes, such as renal insufficency , LVH with strain the benefits of optimizing BP must be weighed against the risk of delaying surgery.
  • 28. REVISED CARDIAC RISK INDEX (cardiac pts undergoing elective major non cardiac procedures)
  • 29. Surgical Risk Stratification (for cardiac pt undergoing non cardiac sx)
  • 30. Clinical Predictors Of Increased Perioperative CVS Risk(MI,CHF,death) MAJOR • Unstable coronary syndromes • Recent MI with evidence ischaemic risk by clinical symptoms or noninvasive study • Unstable or severe angina • Decompensated CHF • Significant arrythmias - High grade AV block, Symptomatic ventricular aarythmias in the presence of underlying heart disease, Supraventricular arrythmias with uncontrolled ventricular rate. • Severe valvular disease.
  • 31. Clinical Predictors Of Increased Perioperative CVS Risk INTERMEDIATE • Mild angina • Prior MI by history or pathological Q waves • Compensated or prior CHF • Diabetes mellitus
  • 32. Clinical Predictors Of Increased Perioperative Cvs Risk MINOR • Advanced age • Abnormal ECG (LVH,LBBB, ST-T abnormalities) • Arrhythmias (e.g- AF) • Low functional capacity (e.g- inability to climb one flight of stairs ) • History of stroke • Uncontrolled systemic HTN
  • 33. Functional Capacity – (MET )Metabolic equivalents • A unit of functional activity • Expressed as a multiple of current metabolic rate to the resting metabolic rate • It is the rate of energy consumption where 1met is the basic metabolic consumption • 1met =3.5mloxygen/kg/min(resting metab consumption) • Lowest met =0.9(sleeping)
  • 34. METS • To withstand the stress of sx pts should achieve 4mets of functional capacity • Perioperative cardiac and long-term risks are elevated in patients unable to obtain 4-MET demand • Able to climb 2flights of stairs without getting tired indicates good reserve - FC>4mets
  • 35. METS
  • 36. METS
  • 37. CENTRAL NERVOUS SYSTEM Problems • Ischemia/vasospasm • Embolism/thrombosis • Tumor • Aneurysm/haemorrhage • Seizures - well controlled or not • stroke • Correlate h/o with physical findings
  • 38. CNS Signs and symptoms • Nausea /vomiting • Vertigo • Headache /vision disturbances • Htn/brady • Focal sensory/motor defecits • Slurred speech • Confusion/disorientation • Coma
  • 39. Peripheral Neuropathy Signs and symptoms • Weakness or loss of function • Tingling/numbness • Cold/pale extremities • Diminished reflexes
  • 40. Peripheral Neuropathy Causes: • Autonomic dysfunction • Dm • Drug induced neuropathy • Nerve compression Get neuro consultation for new symptoms Evaluation prior to regional anaesthesia
  • 41. HEPATIC SYSTEM • H/o jaundice/hepatitis Viral hepatitis • Easily transmitted • Nonsp symptoms like fatigue, malaise, vague abd pain • Symptoms of hepatitis: spider navi , ascites, generalised tremor ,confusion /disorientation
  • 42. HEPATIC SYSTEM Coexsisting diseases • Obesity • Fatty liver • Alcohol abuse • Multiple blood transfusions • Recreational drug use • Coagulation disorders
  • 43. RENAL SYSTEM • Probs wd urination • Chronic cystitis • Prostatitis • Renal calculi • ARF/CRF • Electrolyte abnormalities • Hypervololemia HTN Hyperkalemia
  • 44. RENAL ARF/CRF • Get accurate h/o dialysis schedule , last dialysis, RFT& electrolytes after dialysis Chronic renal failure • Anaemia • Electrolyte abnormalities • Altered drug excretion restricts the choice of anaesthetic agents
  • 45. RESPIRATORY SYSTEM • Detailed History of recent URTI, sorethroat , productive cough, dyspnea(exertion/rest), allergies(hay fever),sleep apnea • Acute disease: URTI/Asthma/Bronchitis/Pneumonia • Chronic disease: COPD/TB • Asthma: duration ,last episode, hospitalisation ,tx (bronchodilators) • COPD-productive cough , smoking packs perday
  • 46. RESPIRATORY SYSTEM Pulmonary complications occurs more frequently than cardiac complications (5-10% incidence ) • Perioperative complications includes: 1. Aspiration 2. Atelectasis 3. Pnuemonia 4. Bronchitis 5. Bronchospasm 6. Hypoxemia 7. AE COPD 8. Respiratiory failure requiring mechanical ventilation
  • 47. Cases where there is markedly increased risk of pulmonary complications • ASA class 3 and class 4 patients ( compared to class 1) • Cigarette smoking • Longer surgeries(>4 h) • Certain types of surgeries:  Abdominal  Thoracic  Aortic aneurysm  Head and neck  Emergency surgery • General anesthesia (compared with cases in which GA was not used)
  • 48. Efforts required for prevention of pulmonary complications • Cessation of smoking prior to surgery • Lung expansion techniques (eg, incentive spirometry) after surgery in patients at risk. • Patients with asthma, have a greater risk for bronchospasm during airway manipulation. • Appropriate use of analgesia and monitoring are key strategies for avoiding postoperative respiratory depression in patients with obstructive sleep apnea.
  • 49. GASTRO INSTESTINAL SYSTEM • Nutritional status • Obese/anorexic • Wt gain/loss • Gastric reflux • Evaluate aspiration risk
  • 50. GASTRO INTESTINAL SYSTEM The risk of aspiration is increased in certain groups of patients • Morbidly Obese • Pregnant women in the second and third trimesters • Hiatus hernia • Full stomach (em sx / trauma) • Serious gastroesophageal reflux disease (GERD).
  • 51. Severe GERD: Treat patients with consistent symptoms (multiple times per week) with • Medications (eg, nonparticulate antacids such as sodium citrate) • Techniques (eg, tracheal intubation)
  • 52. Pharmacological Agents to Reduce the risk of Pulmonary Aspiration • Histamine – 2 Receptor Antagonist : block the ability of histamine to induce secretion of gastric fluid with high hydrogen concentrations e.g. Cimetidine, Ranitidine, Famotidine • Antacids – neutralize the acid in gastric content • Proton pump inhibitors: supress gastric acid secretion by binding proton pump of the parietal cell • Prokinetic agents : Metoclopramide (Dopamine antagonist)
  • 53. COAGULATION ISSUES • How to manage patients who are taking warfarin on a long-term basis(anticoagulants) • How to manage patients who are taking clopidogrel and related agents(antiplatelets) • How to safely provide regional anesthesia to patients who either are receiving long-term anticoagulation therapy or who will receive anticoagulation perioperatively.
  • 54. ANTICOAGULANTS Patients at high risk for thrombosis: Mechanical heart valve implants  Atrial fibrillation Prior thromboembolic stroke Bridging Therapy
  • 55. ANTICOAGULANTS • Patients at lower risk for thrombosis may have warfarin discontinued and then reinitiated after successful surgery. • Decisions regarding bridging therapy often require consultation with the physician who initiated the warfarin therapy
  • 56. ANTIPLATELETS Aspirin • Consider selectively continuing aspirin in patients where the risk of cardiac events is felt to exceed the risk of major bleeding. • If reversal of platelet inhibition is necessary, stop aspirin at least 3 days before surgery. • Do not discontinue aspirin in patients who have drug eluting coronary stents until they have completed 12 months of dual anti platelet therapy.
  • 57. ANTIPLATELETS Thienopyridines (clopidogrel and ticlopidine) • Cataract Surgery –no need to stop • If reversal of platelet inhibition is necessary, then clopidogrel must be stopped 7 days before & Ticlopidine – 14 days before surgery • Do not discontinue them in Pts who have drug eluting stents before 1 year
  • 58. Endocrine And Metabolic Issues • Blood glucose measurement on the morning of elective surgery • Adequacy of longterm blood glucose control - Hba1c . • Abnormally elevated Hba1c - referral to a diabetology service for education ,diet modification and medications to improve metabolic control may be beneficial.
  • 59. Endocrine And Metabolic Issues • Elective surgery should be delayed in patients presenting with marked hyperglycemia • Rearranging the order of scheduled cases to allow insulin infusion to bring the blood glucose concentration closer to the normal range before surgery begins .
  • 60. Endocrine And Metabolic Issues Type1 IDDM End organ disease is common • Retinopathy • Nephropathy • Autonomic dysfunction T2- NIDDM
  • 61. Endocrine And Metabolic Issues Diabetes patients have an increased incidence of • Ischaemic heart disease • Renal dysfunction • Autonomic and peripheral neuropathy • Intra- and postoperative complications
  • 62. Dm - goals of Mx • Maintain blood glucose 100-250mg/dl • Provide adequate fluid volume
  • 63. Endocrine And Metabolic Issues • Hyperthyroid: excessive t3t4 secretion; low TSH • Signs and symps: hypermetab exophthalmous tx propylthiouracil betablockers • Hypothyroid; low t3t4 ; high TSH • Signs and symptoms: low metabolism large tongue • Tx eltroxine
  • 64. Endocrine And Metabolic Issues Hyperparathyroidism: • Hypercalcemia • Increased bone resorption • Reduced renal excretion • Diagnosis; high sr calcium high pth
  • 65. Endocrine And Metabolic Issues Pheochromocytoma: • Tumor of chromaffin tissue • Inc production & release of epinephrine & norepi • S&S: intermittent HTN, headache, sweating, tachy • Diagnosis: inc sr epi , nor epi / Inc urine vinylmandelic acid & metanephrine
  • 66. Endocrine And Metabolic Issues Carcinoid tumors • Slow growing gi tumors • Release vasoactive amines & polypeptides 5hydroxytryptamine • Diarrhoea • Abd cramps • Respi distress/bronchospasm • HTN Histamine abd bradykinin release • Paroxysnal hypotension • Cutaneous flushing • Bronchospasm
  • 67. Endocrine And Metabolic Issues Adrenocortical dysfunction – cushing syndrome • Tx- correct fluid vol status /electrolyte abnorm/ steroids
  • 68. HEMATOLOGIC SYSTEM Anemia • Hb for o2 delivery • Causes acute/chronic anemia • Any benefit from delay of sx • Acute bl loss-poorly tolerated
  • 69. MUSCULOSKLETAL SYSTEM Rheumatoid arthritis • Duration, tx h/o - aspirin /nsaids/ steroids • Chronic anemia • Severely limited movement of their joints makes positioning for surgery and airway maintenance difficult. • Tendency for dislocation of atalnto-occiptal joint • Osteoarthritis • Muscular dystrophies
  • 70. MUSCULOSKLETAL SYSTEM Neuromuscular disorders • Care with muscle relaxants • Coexisting heart disease • Restrictive pulmonary disease
  • 71. OBESITY Determine Ideal bwt and BODY MASS INDEX Ideal bwt (kgs): • Broca Index = ht(cms)-105 women ht(CMS) -100 men BMI=Wt(kg)/Ht(m2)
  • 75. Obstructive sleep apnea • OSA is episodic upper airway narrowing during sleep. • During sleep, the activity of the upper airway dilator muscles decreases in a sleep-stage-dependent manner • This leads to narrowing of the upper airway, loud snoring, and reduction in airflow • Can either be partial (a hypopnoea), or complete (an apnoea). • Apnoea Hypopnoea Index (AHI) The total number of apnoeas and hypopnoeas per hour of sleep Used to describe the severity of OSA
  • 76. Obstructive sleep apnea • OSA severity -AHI No OSA- AHI < 5/h, Mild OSA - AHI 5–15/h, Moderate OSA- AHI 15–30/h Severe OSA- AHI > 30/h • Gold standard - Polysomnography or multi- channel respiratory polygraphy (“sleep study”) • Questionnaires to assess OSA risk - to screen for OSA and to assess the prevalence of OSA
  • 77. STOP BANG questionarre -Screening tool for OSA
  • 78. FAMILY HISTORY • Inherited conditions in the family • History of prolonged apnoea , unexplained death
  • 79. Surgical History & Previous Anaesthesia Exposure Difficulties with previous anaesthetics • Procedure difficulties • Nausea • Vomiting • Dreams • Awareness • Postoperative jaundice
  • 80. Surgical History & Previous Anaesthesia Exposure History of difficulty with venous access • Thrombosis of vein • Look for tattooing
  • 81. DRUG HISTORY AND ALLERGIES • Identify all medications • Prescribed/self-administered • Allergies to- drugs /topical preparations (e.g.iodine)/adhesive dressings/ food
  • 82. SOCIAL HISTORY Alcohol : duration / frequency • Alcohol induction of liver enzymes • Tolerance Smoking: number of cigarettes /amount of tobacco • Nicotine stimulates the sympathetic nervous system causing tachycardia ,hypertension ,coronary artery narrowing, hyperactive airways • Look for withdrawal symptoms
  • 83. Preparation For Anesthesia • Continuing current medications/ treatment of coexisting diseases • Responsibility of the anesthesiologist to instruct patients regarding which medications to continue and which to hold preoperatively
  • 84. Instruct Patients to take the medications with small sips of water, even if fasting! Medications to be Continued on the day of Surgery • Antihypertensives except ACEI is and ARBs • Cardiac medications e.g beta- blockers, digoxin ,antianginal • Antidepressants, anxiolytics and other psychiatric medications • Antiparkinson drugs • Thyroid medications • Birth control pills • Eye drops • Heartburn or reflux medications • Narcotics • Anticonvulsants • Asthma medications • Steroids • Statins
  • 85. Medications to be discontinued • Topical medications e.g creams and ointment • Oral hypoglycemic agents -on the day of sx • Insulin -on the day of sx • Diuretics (except Thiazides for bp or severe HF) - on the day of sx • Sildenafil(similar drugs )-24 hrs before Sx. • NSAIDS –48 hrs before Sx. • Warfarin ( Coumadin) 4 days before Sx • Anticoagulants/antiplatelets
  • 87.
  • 88.
  • 89.
  • 90.
  • 91.
  • 92. Summary The anesthesiologist who takes the time to adequately prepare the patient medically and psychologically for anesthesia and surgery will find that their job of caring for the patient intraoperatively becomes easier, and they are more likely to have a positive outcome as well as a satisfied patient.