Introduction to daily activities of clinical pharmacist.
Drug therapy monitoring,
Medication chart review
Clinical Progress
Pharmacist intervention
Detection and management of ADRs
REVIEWING THE CLINICIANS PRESCRIPTION AND TREATMENT PROGRESSION IS THE FUNDAMENTAL RESPONSIBILITY OF PHARMACIST. THIS PRESENTATION WILL DEAL WITH VARIOUS ASPECTS OF REVIEWING PATIENT DRUGTHERAPY PLAN
Introduction to clinical pharmacy, Concept and Objectives of clinical pharmacy, Function and responsibilities of clinical pharmacist, Clinical Pharmacy services.
Introduction to daily activities of clinical pharmacist.
Drug therapy monitoring,
Medication chart review
Clinical Progress
Pharmacist intervention
Detection and management of ADRs
REVIEWING THE CLINICIANS PRESCRIPTION AND TREATMENT PROGRESSION IS THE FUNDAMENTAL RESPONSIBILITY OF PHARMACIST. THIS PRESENTATION WILL DEAL WITH VARIOUS ASPECTS OF REVIEWING PATIENT DRUGTHERAPY PLAN
Introduction to clinical pharmacy, Concept and Objectives of clinical pharmacy, Function and responsibilities of clinical pharmacist, Clinical Pharmacy services.
A Ward round is a visit made by a medical practitioner, alone or with a team of health care professionals and medical students to hospital in-patients at their bedside to review and follow-up the progress in their health.
Usually at least one ward round is conducted
everyday to review the progress of each
patient outcome.
Pharmacist’s participating in medical ward
rounds promotes health care
Participation of the Pharmacists in ward
rounds in various practice settings helps to
provide rational drug use.
Pharmaceutical care concepts - clinical pharmacy ShaistaSumayya
The pharmaceutical care is defined as “the direct, responsible provision of medication-related care for the purpose of achieving definite outcomes that improve a patient’s quality of life.”
Pharmaceutical care involves the process through which a pharmacist cooperates with a patient and other professional in designing , implementation, and monitoring a therapeutic plan that will produce specific therapeutic outcomes for the patient
In this slides included clinical pharmacy introduction and pharmaceutical care, also explanation about the goals and objectives of the clinical pharmacy requirements
Clinical pharmacy.
History of clinical pharmacy.
Clinical pharmacy requirements.
Clinical pharmacist.
Function of clinical pharmacist.
Basic components of clinical pharmacy practice.
Scope of clinical pharmacy.
How does clinical pharmacy differ from pharmacy?
Clinical pharmacy specialists.
The service including clinical pharmacy/clinical pharmacist.
The service without clinical pharmacy/clinical pharmacist.
Level of action of clinical pharmacist.
Activities of clinical pharmacist.
Information source.
Clinical pharmacy practice areas.
Practice guidelines for pharmacotherapy specialists.
Clinical pharmacokinetics.
Medication related problems.
Drugs that can be monitored.
Status of clinical pharmacy in bangladesh
Scope of clinical pharmacy in bangladesh.
Why clinical,hospital and community pharmacy is essential in bangladesh
A Ward round is a visit made by a medical practitioner, alone or with a team of health care professionals and medical students to hospital in-patients at their bedside to review and follow-up the progress in their health.
Usually at least one ward round is conducted
everyday to review the progress of each
patient outcome.
Pharmacist’s participating in medical ward
rounds promotes health care
Participation of the Pharmacists in ward
rounds in various practice settings helps to
provide rational drug use.
Pharmaceutical care concepts - clinical pharmacy ShaistaSumayya
The pharmaceutical care is defined as “the direct, responsible provision of medication-related care for the purpose of achieving definite outcomes that improve a patient’s quality of life.”
Pharmaceutical care involves the process through which a pharmacist cooperates with a patient and other professional in designing , implementation, and monitoring a therapeutic plan that will produce specific therapeutic outcomes for the patient
In this slides included clinical pharmacy introduction and pharmaceutical care, also explanation about the goals and objectives of the clinical pharmacy requirements
Clinical pharmacy.
History of clinical pharmacy.
Clinical pharmacy requirements.
Clinical pharmacist.
Function of clinical pharmacist.
Basic components of clinical pharmacy practice.
Scope of clinical pharmacy.
How does clinical pharmacy differ from pharmacy?
Clinical pharmacy specialists.
The service including clinical pharmacy/clinical pharmacist.
The service without clinical pharmacy/clinical pharmacist.
Level of action of clinical pharmacist.
Activities of clinical pharmacist.
Information source.
Clinical pharmacy practice areas.
Practice guidelines for pharmacotherapy specialists.
Clinical pharmacokinetics.
Medication related problems.
Drugs that can be monitored.
Status of clinical pharmacy in bangladesh
Scope of clinical pharmacy in bangladesh.
Why clinical,hospital and community pharmacy is essential in bangladesh
Definition of social pharmacy, social pharmacy as a discipline, scope of social pharmacy and role of pharmacist in public health, National Health Mission, National rural health mission, National urban health mission
Organization and objectives of ICH, expedited reporting, ICSR, PSURs, post approval expedited reporting, pharmacovigilance Planning, good clinical practices
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
1. CLINICAL PHARMACY
DR. RAMESH BHANDARI
ASST. PROFESSOR
DEPARTMENT OF PHARMACY PRACTICE
KLE COLLEGE OF PHARMACY, BELAGAVI
1DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
3. DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI 3
Pharmacist
Weigh and
measures
Medicines
Compound
the medicines
Dispense
medicines
Business man
4. Definition of Clinical Pharmacy
Clinical pharmacy is defined as that area of pharmacy
concerned with the science and practice of rational
medication use. (ACCP short definition)
4DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
5. Definition of Clinical Pharmacy
Clinical pharmacy is a health science discipline in which
pharmacists provide patient care that optimizes medication
therapy and promotes health, wellness, and disease
prevention. (ACCP detailed definition)
5DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
6. Clinical Pharmacy in India
India’s first degree in pharmacy at Banaras Hindu
University established under the able leadership of
professor Mahadeva Lal Schroff.
A statutory body established to control the standards
of the pharmacy profession known as PCI.
In 1948 - Pharmacy Act was drafted under the aegis
of Pharmacy council of India (PCI).
6DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
7. Clinical Pharmacy in India
First education regulation in 1953, Diploma in
pharmacy became the minimum qualification
required to practise pharmacy in India
irrespective of setup.
The education regulations were subsequently
revised in 1972, 1981 and 1991.
7DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
8. Clinical Pharmacy in India
Traditional pharmacist’s education and
practice was oriented towards the
Pharmaceutical Industry.
Hence, most graduates employed in the area of
production, formulation, quality control and
marketing.
8DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
9. Clinical Pharmacy in India
During the 1980s and 1990s, the consequences
of drug misuse, such as poor health outcomes
from drug treatment, antibiotic resistance,
adverse drug reactions (ADRs) and economic
loss to patients and the wider health care system
are acknowledged by both pharmacy and
medical profession.
9DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
10. Clinical Pharmacy in India
Having recognized the need for pharmacists to
assume new responsibilities in health care
remained a problem.
Existing knowledge and skills in
pharmaceutics, pharmaceutical chemistry,
pharmacology and industrial pharmacy.
10DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
11. Clinical Pharmacy in India
Different set of knowledge required by
pharmacist wishing to contribute to patient care.
Those includes pathophysiology, applied
therapeutics, clinical pharmacokinetics and
practice skills such as patient counselling, drug
information and drug therapy review.
11DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
12. Clinical Pharmacy in India
In 1991 revised education regulations –
addition of subjects of hospital and clinical
pharmacy, community pharmacy and health
education, and drug store and business
management in the diploma of pharmacy
curriculum.
12DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
13. Clinical Pharmacy in India
Lack of teaching personnel hindered the
development of clinical pharmacy.
Later with the support from overseas academic
leaders of the profession started first master in
pharmacy practice program at JSS College of
Pharmacy, Mysore and ooty in 1997.
13DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
14. Clinical Pharmacy in India
In 1998, Sri Ramakrishna Institute of
Paramedical Sciences, Coimbatore and its
attached hospital initiated clinical pharmacy.
In 1999, KLE College of Pharmacy, Belgaum
began clinical pharmacy practice and education
program using the KLEs Hospital as a teaching
base.
14DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
15. Clinical Pharmacy in India
In 2001, similar program were established by
Manipal university through manipal college of
Pharmaceutical sciences; Al-Ameen college of
pharmacy, Bangalore and then by Annamalai
university of Tamil Nadu.
15DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
16. Clinical Pharmacy in India
Later in kerala, Government college of
pharmacy, Trivandrum then National Institute of
Pharmaceutical Education and Research
(NIPER), Punjab also started Pharmacy Practice.
16DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
17. Clinical Pharmacy in India
As of 2011, 23 institutions are offering
postgraduate program in pharmacy practice.
In 2008 – commencement of doctor of
Pharmacy program in many institutions and
Pharm. D Post baccalaureate in some colleges.
17DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
19. Scope of Clinical Pharmacy
Professional Services:
Drug information services
Clinical pharmacy inputs on ward rounds
Information about new drugs
Patient counselling and advice on individual
patient management.
19DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
20. Scope of Clinical Pharmacy
Detection and management of ADRs
Choice of antibiotics
Dose adjustment in renal/hepatic impairment
Dose adjustment to special population
Finding possible drug interactions
20DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
21. Scope of Clinical Pharmacy
Preparation of treatment guidelines or
protocols,
Education of nurses about preparation and
administration of parenteral drugs
Intervention to reduce medication errors
Support for clinical research activities
21DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
22. Scope of Clinical Pharmacy
At community pharmacy level:
Used to counsel the patients about their
medications
Identify drug interactions and other drug
related problems
22DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
23. SUMMARY
Still, pharmacy profession in India is in
transition from industry to clinical oriented.
23DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI
24. REFERENCE
G. Parthasarathi, Karin Nyfort Hansen, Milap
C Nahata. A textbook of clinical pharmacy
practice Essential concepts and skills.
Universities Press. 2nd edition.
24DEPARTMENT OF PHARMACY PRACTICE, KLE COLLEGE OF PHARMACY, BELAGAVI