This document provides guidance on performing interventional radiology procedures using ultrasound guidance. It discusses selecting an optimal puncture site using ultrasound to identify the shortest skin-target distance and avoid vital structures. Real-time ultrasound visualization allows monitoring of the needle trajectory. Procedures are usually done on an outpatient basis if the patient is cooperative with a family member present. Precautions like fasting and stopping anticoagulants beforehand are recommended. Ultrasound probes and materials must be properly sterilized. The "free-hand" technique allows real-time adjustment of the needle angle under ultrasound guidance. Biopsy needles vary in size and shape depending on the target tissue and goal of obtaining cytology or histology samples. Potential