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Flexible Endoscopy:
The Surgical Perspective
Jonathan Pearl, MD
History of Surgical Endoscopy
Kelly, 1895 Hirschowitz, 1957
McCune, 1968 Shinya, 1968
History
• Kelly, 1895, sigmoidoscopy
• McCune, 1968, ERCP
• Shinya and Wolf, 1975, polypectomy
• Sugawa, 1975, Endoscopic treatment of UGIB
• Ponsky, 1975, colonoscopic tattooing
• Ponsky and Gauderer, 1979, PEG
• Stiegman, 1980, band ligation
Endoscopy Volume
• 2434 surgeons sitting for recertification 1995-
1997
• Average number of total procedures: 400
• 51 (13%) endoscopic procedures
– 21 Colonoscopy
– 15 EGD
– 3 PEG
– Flex sig, bronch
Ritchie, WP et al. Ann Surg. 1999; 230(4): 533.
Endoscopy Volume
• 10-year update
– 4968 recertifying surgeons, 2007-2009
• 533 annual procedures
• Endoscopy procedures
–Urban surgeons: 39
–Rural surgeons (large population): 214
–Rural surgeons (small population): 320
Valentine RJ, et al. Ann Surg. 2011; 254(3):520-6
Surgeons do Endoscopy Well
• 13,580 surgeon-performed colonoscopies
• Prospective database
• 92% completion rate
• 34% polyp detection rate
• Low rates of complications
– 10 bleeds, 10 perforation
• Experience matters
– Higher completion rates with >100/yr
Wexner et at. Surg Endosc. 2001; 15(3); 251-261.
Surgeons do Endoscopy Well
• 558 colonoscopy patients in VAMC
• All colonoscopies performed by colorectal
surgeons
• Surgeons met all standard quality measures
– 99% performed for ASGE-approved indication
– 97% cecal intubation rate
– Adenoma detection rate 26%
– 1 post-polypectomy bleed, 1 perforation
Tran Cao HS, et al. Surg Endosc. 2009. 23:2364-8
Navy Data
• 566 colonoscopies by colorectal and general
surgeons
• 97% cecal intubation
• 27% adenoma detection
• No perforation
• No post-polypectomy bleed
Training Requirements
• RRC Requirements increased in 2009
– 50 colonoscopies
– 35 EGDs
• University of Maryland residents
– 50-55 colonoscopies
– 50 EGDs, including PEG
Position Paper
• ASGE, ACG, AGA
• Concerns about ABS training numbers
– “…inadequate especially when surgical residents
are required to perform only a fraction of the
procedures requires to assess competency”
– Places undue burden on GI to achieve numbers
Competency
• ASGE: minimum thresholds before
competency can be assessed
– 140 colonoscopies
– 130 EGD
– 200 ERCP
• SAGES: Fulfill RRC requirements
– Privileges granted by local authorities
Are numbers important?
• Want proficiency, not familiarity
• Pushback from GI
• Difficulty obtaining privileges
Surgical Endoscopy Program
• Single center instituted a dedicated surgical
endoscopy program for residents
– 2 dedicated days
– Residents at all levels
– 4 year retrospective review
• Avg scopes 1999 graduates: 21
• Avg scopes 2005 residents: 161
Morales MP, et al. Surg Endosc. 2008. 22(9)2013-7.
Postgraduate Fellowship
• 3 programs with focus on endoscopy
– Louisville
– Miami
– Case Western
• 100-200 colonoscopy
• 200-300 EGD
• 150-200 ERCP
How about simulation?
VR Simulation
• Early data discouraging
– Construct validity of VR simulators
– GI Fellow training
• 10 hours of simulation training
– Useful for familiarization with equipment and
technique
– No clinical difference after 15 colonoscopies
Cohen J, et al. GIE. 2006; 64:361-8.
VR Simulation
• 36 trainees randomized to simulator training
vs clinical training
– 16 hours simulation training vs 16 hours patient-
based training
– After training tested on simulator then 3 clinical
cases
– Simulation group better on simulator
– No difference in clinical colonoscopy
Haycock at al, GIE. 2010; 71(2)298-307
Physical Models
Validation of Physical Simulator
• 21 experienced and 18 novices
• Showed construct validity
Plooy AM, et el. GIE. 2012;76(1):144-50.
Fundamentals of Endoscopic Surgery
• Currently in development by SAGES
• Didactic and skills-based
• VR Simulator
• 5 specific tasks
– Navigation, Tool manipulation, Mucosal
Inspection, Retroflexion, Loop Reduction
Back to Proficiency
• Goal of training in endoscopy
– Proficiency, not familiarity
• Simulation may help in early training
• Numerical milestones inadequate
• Need a tool to accurately assess proficiency
GAGES
• Global assessment of 60 novices and 79 experts
• 2 expert observers
• Results
– Construct validity
– Easy to use
– External validity (multiple sites)
• May contribute to the definition of technical
proficiency in basic endoscopy
Vassiliou et al. Surg Endosc. 2010; 24: 1834-41.
Importance of Proficiency
• Comprehensive care of GI Surgery patients
– Screening colonoscopy
– Follow up for colon cancer
– EGD for GERD
– Localize colon cancer
– EGD in bariatric patients
Intraoperative Endoscopy
Can endoscopy supplant UGI?
• 34 patients undergoing LPEHR
• EGD after dissection and after wrap
• No leaks, no wrap abnormalities
• All underwent UGI
– 1 column of barium
• EGD may supplant UGI in LPEHR
EGD during LRYGB
• Retrospective review of 2311 patients
• Intraop leak detected in 80 patients
– Suture line reinforced in 46
– 34 leaks only at high pressure
• Post op leaks detected in 4 patients
– 2 had intraop leaks which had been reinforced
Haddad A, et al. Obes Surg. 2012.
Pneumatic Testing during LRYGB
• 257 consecutive patients
• Roux limb clamped; insufflation with
endoscope
• Intraop air leaks in 25 patients
– 13 persistent air leaks (repaired and drained)
– 12 non-reproducible (drainage alone)
– 2 post op leaks—not at G-J anastamosis
Kligman MD. Surg Endosc. 2007; 21:1403-5.
Managing Post op Complications
Stents
• Meta-analysis of 7 studies
• 67 LRYGB patients with leaks
• 88% closure with stents
• 17% stent migration
Puli SR, et al. GIE. 2012; 75(2):287-93.
Clips
Endoscopic Suturing
Endoscopic Suturing
Dilating Strictures
Reducing Stoma Diameter
Thompson CC, et al. Surg Endosc. 2006; 20(11):1744-8.
Endoscopy after Fundoplication
• Tight fundoplication
– Early—wait
– Late—Balloon dilation
• Delayed gastric emptying
– ?Injury to vagus nerves
• Dilate pylorus, BOTOX injection
• Late dysphagia
– Dilate fundoplication
PEG Proficiency
• 160,000-200,000 PEGs performed annually in
US
• Morbidity in 9%
• Major complications in 1-3% of cases
• Mortality in 0.5%
Avoiding PEG Complications
• Does endoscopic experience matter?
• Does it matter who performs PEG?
• Are there techniques to reduce complications?
Endoscopic Innovations in Surgery
• NOTES
• TIF
• BARRX
• Bariatrics
• Resections
• Closure of Perforations
• POEM
TIF
TIF
Before After
TIF Data
• 100 consecutive reflux patients in 10 centers
• GERD-HRQL normalized in 73%
• 80% off PPIs at 6 months
• Significant reductions in reflux and
regurgitation scores
• No pH data
Bell at al. J Am Coll Surg. Aug 2012.
BARRX
RFA
• 90% eradication of low-grade dysplasia
• 80% eradication of high-grade dysplasia
• Ablation group
– 3% disease progression
– No invasive esophageal cancer
Endoscopy in Bariatrics
Gastrojejunal Barrier
Full thickness resection
Over the scope clips for GI perforation
POEM
Long-Term Outcomes
• 18 cases over 1 year
• 1 full-thickness perforation
• All 18 with dysphagia relief
• 2 patients with non-cardiac chest pain
• 50% with reflux at 6 mos on pH probe
– 6 patients complained of pyrosis
Swanstrom LL, et al. Ann Surg. Oct 2012.
Summary
• Surgeons perform endoscopy well
• Endoscopic training should focus on
proficiency
• Proficient endoscopists provide
comprehensive care to GI surgical patients
• Many surgical innovations have endoscopic
platform
• Endoscopy will be integral in GI surgery
Flexible endoscopy a surgeon's perspective

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Flexible endoscopy a surgeon's perspective

  • 1. Flexible Endoscopy: The Surgical Perspective Jonathan Pearl, MD
  • 5. History • Kelly, 1895, sigmoidoscopy • McCune, 1968, ERCP • Shinya and Wolf, 1975, polypectomy • Sugawa, 1975, Endoscopic treatment of UGIB • Ponsky, 1975, colonoscopic tattooing • Ponsky and Gauderer, 1979, PEG • Stiegman, 1980, band ligation
  • 6. Endoscopy Volume • 2434 surgeons sitting for recertification 1995- 1997 • Average number of total procedures: 400 • 51 (13%) endoscopic procedures – 21 Colonoscopy – 15 EGD – 3 PEG – Flex sig, bronch Ritchie, WP et al. Ann Surg. 1999; 230(4): 533.
  • 7. Endoscopy Volume • 10-year update – 4968 recertifying surgeons, 2007-2009 • 533 annual procedures • Endoscopy procedures –Urban surgeons: 39 –Rural surgeons (large population): 214 –Rural surgeons (small population): 320 Valentine RJ, et al. Ann Surg. 2011; 254(3):520-6
  • 8. Surgeons do Endoscopy Well • 13,580 surgeon-performed colonoscopies • Prospective database • 92% completion rate • 34% polyp detection rate • Low rates of complications – 10 bleeds, 10 perforation • Experience matters – Higher completion rates with >100/yr Wexner et at. Surg Endosc. 2001; 15(3); 251-261.
  • 9. Surgeons do Endoscopy Well • 558 colonoscopy patients in VAMC • All colonoscopies performed by colorectal surgeons • Surgeons met all standard quality measures – 99% performed for ASGE-approved indication – 97% cecal intubation rate – Adenoma detection rate 26% – 1 post-polypectomy bleed, 1 perforation Tran Cao HS, et al. Surg Endosc. 2009. 23:2364-8
  • 10. Navy Data • 566 colonoscopies by colorectal and general surgeons • 97% cecal intubation • 27% adenoma detection • No perforation • No post-polypectomy bleed
  • 11. Training Requirements • RRC Requirements increased in 2009 – 50 colonoscopies – 35 EGDs • University of Maryland residents – 50-55 colonoscopies – 50 EGDs, including PEG
  • 12. Position Paper • ASGE, ACG, AGA • Concerns about ABS training numbers – “…inadequate especially when surgical residents are required to perform only a fraction of the procedures requires to assess competency” – Places undue burden on GI to achieve numbers
  • 13. Competency • ASGE: minimum thresholds before competency can be assessed – 140 colonoscopies – 130 EGD – 200 ERCP • SAGES: Fulfill RRC requirements – Privileges granted by local authorities
  • 14. Are numbers important? • Want proficiency, not familiarity • Pushback from GI • Difficulty obtaining privileges
  • 15. Surgical Endoscopy Program • Single center instituted a dedicated surgical endoscopy program for residents – 2 dedicated days – Residents at all levels – 4 year retrospective review • Avg scopes 1999 graduates: 21 • Avg scopes 2005 residents: 161 Morales MP, et al. Surg Endosc. 2008. 22(9)2013-7.
  • 16. Postgraduate Fellowship • 3 programs with focus on endoscopy – Louisville – Miami – Case Western • 100-200 colonoscopy • 200-300 EGD • 150-200 ERCP
  • 18. VR Simulation • Early data discouraging – Construct validity of VR simulators – GI Fellow training • 10 hours of simulation training – Useful for familiarization with equipment and technique – No clinical difference after 15 colonoscopies Cohen J, et al. GIE. 2006; 64:361-8.
  • 19. VR Simulation • 36 trainees randomized to simulator training vs clinical training – 16 hours simulation training vs 16 hours patient- based training – After training tested on simulator then 3 clinical cases – Simulation group better on simulator – No difference in clinical colonoscopy Haycock at al, GIE. 2010; 71(2)298-307
  • 21. Validation of Physical Simulator • 21 experienced and 18 novices • Showed construct validity Plooy AM, et el. GIE. 2012;76(1):144-50.
  • 22.
  • 23.
  • 24. Fundamentals of Endoscopic Surgery • Currently in development by SAGES • Didactic and skills-based • VR Simulator • 5 specific tasks – Navigation, Tool manipulation, Mucosal Inspection, Retroflexion, Loop Reduction
  • 25.
  • 26. Back to Proficiency • Goal of training in endoscopy – Proficiency, not familiarity • Simulation may help in early training • Numerical milestones inadequate • Need a tool to accurately assess proficiency
  • 27.
  • 28. GAGES • Global assessment of 60 novices and 79 experts • 2 expert observers • Results – Construct validity – Easy to use – External validity (multiple sites) • May contribute to the definition of technical proficiency in basic endoscopy Vassiliou et al. Surg Endosc. 2010; 24: 1834-41.
  • 29. Importance of Proficiency • Comprehensive care of GI Surgery patients – Screening colonoscopy – Follow up for colon cancer – EGD for GERD – Localize colon cancer – EGD in bariatric patients
  • 31. Can endoscopy supplant UGI? • 34 patients undergoing LPEHR • EGD after dissection and after wrap • No leaks, no wrap abnormalities • All underwent UGI – 1 column of barium • EGD may supplant UGI in LPEHR
  • 32. EGD during LRYGB • Retrospective review of 2311 patients • Intraop leak detected in 80 patients – Suture line reinforced in 46 – 34 leaks only at high pressure • Post op leaks detected in 4 patients – 2 had intraop leaks which had been reinforced Haddad A, et al. Obes Surg. 2012.
  • 33. Pneumatic Testing during LRYGB • 257 consecutive patients • Roux limb clamped; insufflation with endoscope • Intraop air leaks in 25 patients – 13 persistent air leaks (repaired and drained) – 12 non-reproducible (drainage alone) – 2 post op leaks—not at G-J anastamosis Kligman MD. Surg Endosc. 2007; 21:1403-5.
  • 34. Managing Post op Complications
  • 35.
  • 36. Stents • Meta-analysis of 7 studies • 67 LRYGB patients with leaks • 88% closure with stents • 17% stent migration Puli SR, et al. GIE. 2012; 75(2):287-93.
  • 37. Clips
  • 38.
  • 39.
  • 42.
  • 44. Reducing Stoma Diameter Thompson CC, et al. Surg Endosc. 2006; 20(11):1744-8.
  • 45. Endoscopy after Fundoplication • Tight fundoplication – Early—wait – Late—Balloon dilation • Delayed gastric emptying – ?Injury to vagus nerves • Dilate pylorus, BOTOX injection • Late dysphagia – Dilate fundoplication
  • 46. PEG Proficiency • 160,000-200,000 PEGs performed annually in US • Morbidity in 9% • Major complications in 1-3% of cases • Mortality in 0.5%
  • 47.
  • 48. Avoiding PEG Complications • Does endoscopic experience matter? • Does it matter who performs PEG? • Are there techniques to reduce complications?
  • 49. Endoscopic Innovations in Surgery • NOTES • TIF • BARRX • Bariatrics • Resections • Closure of Perforations • POEM
  • 50. TIF
  • 51. TIF
  • 53. TIF Data • 100 consecutive reflux patients in 10 centers • GERD-HRQL normalized in 73% • 80% off PPIs at 6 months • Significant reductions in reflux and regurgitation scores • No pH data Bell at al. J Am Coll Surg. Aug 2012.
  • 54. BARRX
  • 55.
  • 56.
  • 57.
  • 58.
  • 59. RFA • 90% eradication of low-grade dysplasia • 80% eradication of high-grade dysplasia • Ablation group – 3% disease progression – No invasive esophageal cancer
  • 61.
  • 63.
  • 65. Over the scope clips for GI perforation
  • 66.
  • 67.
  • 68.
  • 69. POEM
  • 70.
  • 71.
  • 72.
  • 73. Long-Term Outcomes • 18 cases over 1 year • 1 full-thickness perforation • All 18 with dysphagia relief • 2 patients with non-cardiac chest pain • 50% with reflux at 6 mos on pH probe – 6 patients complained of pyrosis Swanstrom LL, et al. Ann Surg. Oct 2012.
  • 74. Summary • Surgeons perform endoscopy well • Endoscopic training should focus on proficiency • Proficient endoscopists provide comprehensive care to GI surgical patients • Many surgical innovations have endoscopic platform • Endoscopy will be integral in GI surgery