Single injection caudal blocks are a common regional anesthetic technique for pediatric surgery involving dermatomes below T10. The technique involves identifying the sacral hiatus using surface anatomy landmarks or ultrasound and inserting a needle to inject local anesthetic with or without adjuvants. Key factors for success include careful identification of anatomy to avoid intravascular or intrathecal injection, use of test dosing to confirm proper placement, and selection of local anesthetics and adjuvants to provide effective pain control. Close monitoring is required after the block due to risks of local anesthetic toxicity, infection, or neurological injury.