This document provides information about spinal anesthesia including:
- Definitions and the advantages of spinal anesthesia such as reduced risk of respiratory complications.
- Indications for spinal anesthesia including lower body and pelvic surgeries.
- Relevant anatomy including dermatomes, vertebrae, and spinal cord landmarks.
- How to perform a spinal anesthetic including patient positioning, identifying the injection site, and inserting the spinal needle.
- Factors that influence the level and duration of the spinal block such as drug choice, dosage, and patient characteristics.
- Potential complications of spinal anesthesia.
A powerpoint explaining in detail about all the intravenous induction agents and their clinical uses, pharmacokinetics & pharmacodynamics, adverse effects and complications.
In critical care medicine the invasive life saving techniques are often employed and when all goes well such interventions will be withdrawn to all for normal physiology to resume. Identifying this point for safe withdrawal for the resumption of normal respiratory function is of utmost importance.
A powerpoint explaining in detail about all the intravenous induction agents and their clinical uses, pharmacokinetics & pharmacodynamics, adverse effects and complications.
In critical care medicine the invasive life saving techniques are often employed and when all goes well such interventions will be withdrawn to all for normal physiology to resume. Identifying this point for safe withdrawal for the resumption of normal respiratory function is of utmost importance.
The transversus abdominis plane, more commonly referred to as the TAP block,
Places local anesthetic in the lateral abdominal wall in a plane between the internal oblique and the transversus abdominis muscles.
Here, the local anesthetic block can block many of the abdominal nerves as they pass to the abdominal structures.
Complete Description about Spinal anesthesia.
Topics which these slides cover are:
History
Anatomy
Blood supply of spinal cord
Indications and contraindications
Position
Procedure
Technique
Spinal needles
Factors affecting block height
Testing of block
Drugs of anesthesia
Complications
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The dimensions of healthcare quality refer to various attributes or aspects that define the standard of healthcare services. These dimensions are used to evaluate, measure, and improve the quality of care provided to patients. A comprehensive understanding of these dimensions ensures that healthcare systems can address various aspects of patient care effectively and holistically. Dimensions of Healthcare Quality and Performance of care include the following; Appropriateness, Availability, Competence, Continuity, Effectiveness, Efficiency, Efficacy, Prevention, Respect and Care, Safety as well as Timeliness.
One of the most developed cities of India, the city of Chennai is the capital of Tamilnadu and many people from different parts of India come here to earn their bread and butter. Being a metropolitan, the city is filled with towering building and beaches but the sad part as with almost every Indian city
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
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Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
Defecation
Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out
The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool.
Normal defecation is painless, resulting in passage of soft, formed stool
CONSTIPATION
Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces
IMPACTION
Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon.
DIARRHEA
Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration
HEMORRHOIDS
Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal.
FLATULENCE
As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus)
FECAL INCONTINENCE
Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image
PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY,
An enema is the instillation of a solution into the rectum and sig
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Antibiotic Stewardship by Anushri Srivastava.pptxAnushriSrivastav
Stewardship is the act of taking good care of something.
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels.
ACCORDING TO apic.org,
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
ACCORDING TO pewtrusts.org,
Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate
According to WHO,
Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials
In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis.
Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance.
According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites
VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way
GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory
to prevent antimicrobial overuse, misuse and abuse.
to minimize the developme
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CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdfSachin Sharma
This content provides an overview of preventive pediatrics. It defines preventive pediatrics as preventing disease and promoting children's physical, mental, and social well-being to achieve positive health. It discusses antenatal, postnatal, and social preventive pediatrics. It also covers various child health programs like immunization, breastfeeding, ICDS, and the roles of organizations like WHO, UNICEF, and nurses in preventive pediatrics.
3. Outline
1. Definition
2. Advantages
3. Indications and Contra-indications
4. Anatomy
5.How to perform the spinal anesthesia?
6. Complications of Spinal Anesthesia
4. DEFINITION OF REGIONAL
ANESTHESIA
Local anesthetic applied around a peripheral nerve at any
point along the length of the nerve (from spinal cord)-
reducing or preventing impulse transmission
No CNS depression; patient conscious
Regional anesthetic techniques categorized as follows
Spinal anesthesia and Epidural
Peripheral nerve blockades
5. The Advantages of Spinal Anaesthesia
1. Cost. The costs associated with SPA are minimal.
2. Patient satisfaction. the majority of patients are very
happy with this technique.
3. Respiratory disease. SPA produces few adverse
effects on the respiratory system as long as unduly
high blocks are avoided.
4. Patent airway. As control of the airway is not
compromised, there is a reduced risk of airway
obstruction or the aspiration of gastric contents.
6. Contd…
5. Diabetic patients. There is little risk of unrecognised
hypoglycaemia in an awake patient.
6. Muscle relaxation. SPA provides excellent muscle
relaxation for lower abdominal and lower limb
surgery.
7. Bleeding. Blood loss during operation is less than
when the same operation is done under general
anaesthesia.
7. Contd…
8. Splanchnic blood flow. Because of its effect on
increasing blood flow to the gut, spinal anaesthesia
reduces the incidence of anastomotic dehiscence.
9. Visceral tone. The bowel is contracted by SPA and
sphincters relaxed although peristalsis continues.
Normal gut function rapidly returns following surgery.
10. Coagulation. Post-operative deep vein thromboses
and pulmonary emboli are less common following
spinal anaesthesia.
8. Indication of SA
Subarachnoid block can be used to provide surgical
anesthesia for all procedures carried out on the lower
half of the body.
Indications include surgery on the lower limb, pelvis,
genitals, and perineum, and most urological
procedures.
Can be used for analgesia (Intrathecal opoid)
9. Derma
tomal
Level
Surface Landmark
C8 Little finger
T1,T2 Inner aspect of the arm
T4 Nipple line, root of
scapula
T7 Inferior border of
scapula ,Tip of xiphoid
T10 Umbilicus
L2 to
L3
Anterior thigh
S1 Heel of foot
Dermatomes
10. SURFACE ANATOMY
Anatomic Landmarks to Identify Vertebral
Levels
Anatomic
Landmark
Features
C7 Vertebral prominence, the most
prominent process in the neck
T7 Inferior angle of the scapula
L4 Line connecting iliac crests
S2 Line connecting the posterior
superior iliac spines
Sacral
hiatus
Groove or depression just above
or between the gluteal clefts
above the coccyx
11. Spinal Cord
Extends from foramen magnum to
Adult : lower border of L1 in /upper
border of L2
Infants/children : L3
It is about 45 cm long
Duramater, Subarachnoid space &
subdural space: S2 in adults( S3 in
children)
S. C gives 31 pairs of spinal nerve
An extension of piamater , the FILUM
TERMINALE penetrate the dura and attach
the terminal end of spinal cord [conus
medullaris]to the periosteum of the coccyx
13. Important Facts
Cardiac accelerator fibre: T1-T4(Bradycardia & ↓
contractility)
Vasomotor fibre : T5-L1( Determine vasomotor
tone)(vasodilation on blockade)
Sympathetic outflow arise from T5-L1(Block ↑vagal
tone, small contacted gut with active peristalsis)
Most dependent part in supine position is T4-T8 (imp.
For hyperbaric solution)
14. SITE
Adult : L3-L4 or L4-L5 ( or even
L2-L3)
Infant : L4-L5
A line drawn b/w the highest pt. of
iliac crests (Tuffier’s line) usually
cross either body of L4 or the L4-
L5 interspace
Position
Sitting
lateral
Prone(anorectal procedure,
hypobaric solution, jackknife position)
15. Positioning the Patient
Sitting
With Legs hanging over side of bed
Put Feet up on a Stool (no wheels)
Assistant MUST keep the patient from Swaying
Curve her back like a “C”,
Lateral Decubitus (Left or Right?)
Needs to be Parallel to the Edge of the Bed
Legs Flexed up to Abdomen
Forehead Flexed down towards Knees
Jack-knife Position
Chosen for ano-rectal surgery
CSF will not drip from hub of needle
Use hypobaric solution
17. .
The patient and operating table should then be placed in
the position appropriate for the surgical procedure and
drugs chosen.
Lateral decubitus positioning for a neuraxial
block. The assistant can help the patient
assume the ideal position of “forehead to
knees.”
Anesthetic dose is injected at a rate of approximately
0.2 mL/sec
18. Spinal Anesthesia
A single injection of a local anesthetic solution into
the subarachnoid space usually at the lumbar level
Intrathecal Narcotics
Commonly at L3-L4
Largest Interspace
L5-S1
19. How to perform the spinal
injection?
Insert the needle: the structures that will
be passed
skin , subcutaneous tissue, supraspinous ligament ,
interaspinous ligament , lagementum flavum ,
dura mater.
20. Important Factors Affecting Block
Height - SAB
Baricity of anesthetic solution
Position of the patient
During injection
Immediately after injection
Drug Dosage (mg)
Concentration times volume
Addition of Opioids
Site of Injection
21. Additional Factors to Consider
with SAB Height
Patient Age
Elderly patients > 80 yrs
Patient Height
Intra-abdominal Pressure
Pregnancy & Obesity
Drug Volume
22. Differential Block with SAB
Sympathetic Block- 2-6 dermatomes higher than the
sensory block
Motor Block- 2 dermatomes lower than sensory
block
23. When performing a spinal anesthetic, appropriate
monitors should be placed, and airway and
resuscitation equipment should be readily available.
All equipment for the spinal blockade should be ready
for use, and all necessary medications should be drawn
up prior to positioning the patient for spinal anesthesia.
Adequate preparation for the spinal reduces the
amount of time needed to perform the block and assists
with making the patient comfortable.
Proper positioning is the key to making the spinal
anesthetic quick and successful.
Technique of Lumbar Puncture
24. Once the patient is correctly positioned, the midline
should be palpated. The iliac crests are palpated, and a
line is drawn between them in order to find the body of L4
or the L4-5 interspace.
Other interspaces can be identified, depending on where
the needle is to be inserted.
The skin should be cleaned with sterile cleaning solution,
and the area should be draped in a sterile fashion.
A small wheal of local anesthetic is injected into the skin
at the site of insertion.
More local anesthetic is then administered along the
intended path of the spinal needle insertion to a depth of 1
to 2 in.
25. 1. MIDLINE APPROACH
2. PARAMEDIAN APPROACH
Midline Approach Paramedian
approach
Skin Skin
Subcutaneous fat Subcutaneous fat
Supraspinous ligament
Interspinous ligament
Ligamentum flavum Ligmentum flavum
Dura mater Dura mater
Subdural space Subdural space
Arachnoid mater Arachnoid mater
Subarachnoid space Subarachnoid space
Spinal : approaches
Structure Pierced
26. Midline Approach
The back should be draped in a sterile fashion.
With advancement of needle Two “pops” are felt. The
first is penetration of the L. flavum & second is the
penetration of dura-arachnoid membrane.
The stylet is then removed, and CSF should appear
at the needle hub.
For spinal needles of small gauge (26-29 gauge), this
usually takes 5-10 sec
27. Paramedian Approach
•Calcified interspinous ligament or difficulty in flexing the
spine
•The needle should be inserted 1 cm lateral and 1 cm
inferior of the superior spinous process of desired level.
Angle should be 10-25 toward midline
•The ligamentum flavum is usually the first resistance
identified.
28. SPINAL NEEDLE
QUINCKE WHITACRE SPROTEE
Spinal needles fall into two
main categories:
(i) those that cut the dura :
Quincke- Babcock
needle, the traditional
disposable spinal needle
(iI) those with a conical
tip(Pencil tip) : Whitacre
and Sprotte needles
If a continuous spinal
technique is chosen, use of
a Tuohy or Hustead needle
can facilitate passage of the
catheter
29. Blunt tip (pencil-point)
needle decreased the
incidence of PDPH
Sprotte is a side-
injection needle with a
long opening.
It has the advantage of
more vigorous CSF flow
compared with similar
gauge needles.
30. Differential blockade
„ Autonomic>sensory>motor
Sensitivity to blockade determined by
axonal diameter, degree of myelination, anatomy
„ Sympathetic blockade may be two dermatomes
higher than sensory block (pain, light touch)
Mechanism of Action
31. Baricity of Local Anesthetics
Isobaric – Stays where you put it
LA has the same density or specific gravity as CSF
(1.003-1.008) – Normal Saline
Hypobaric – “Floats” up – Lighter than CSF
LA has a density or specific gravity that is less than
CSF (<1.003) – Sterile Water
Hyperbaric – Settles to Dependent aspect of the
subarachnoid space – Heavier than CSF
LA has a density or specific gravity that is greater
than CSF (>1.008) - Dextrose
32. Hypobaric and Isobaric Spinal Anesthesia
To make a drug hypobaric to CSF, it must be less
dense than CSF, with a baricity appreciably less than
1.0000 or a specific gravity appreciably less than
1.0069 (the mean value of the specific gravity of CSF).
A common method of formulating a hypobaric
solution is to mix solution with sterile water & for
hyperbaric mix with dextrose
33. Local
Anesthetic
Mixture
Dose (mg) * Duration (min)
To T10 To T4 Plain
Epinephrine
, 0.2 mg
Lidocaine (5%
in 7.5%
dextrose)
50-60 75-100 60 75-100
Tetracaine
(0.5% in 5%
dextrose)
6-8 10-16 70-90 100-150
Bupivacaine
(0.75% in
8.5%
dextrose)
8-10 12-20 90-120 100-150
Ropivacaine
(0.5% in
dextrose)
12-18 18-25 80-110 —
Levobupivaca
ine
8-10 12-20 90-120 100-150
* Doses are for use in a 70-kg
Drug Selection for Hyperbaric Spinal Anesthesia(Miller)
34. Fentanyl(<25µg)
Clonidine(25-50µg) an α2-agonist, prolongs the motor &
sensory blockade
Dexmedetomidine (3-5 µg)
Neostigmine: inhibits the breakdown of acetylcholine
and thereby induces analgesia.
It also prolongs and intensifies the analgesia
Epinephrine (0.2 mg) or phenylephrine (5 mg)
Spinal Anesthetic Additives
35. In patients should be allowed to leave the recovery
room after spinal anesthesia as soon as it can be
demonstrated that their block is receding appropriately
(at least four dermatomes’ regression or a spinal
level of less than T10), they are hemodynamically
stable, and they are comfortable.
Outpatients should be able to ambulate without
orthostatic changes and void before discharge if they
are in a high-risk group for urinary retention
36. Contraindications of Spinal
ABSOLUTE
Infection at the site of injection
Patient refusal
Coagulopathy and other bleeding disorders
Severe hypovolemia
Increased intracranial pressure
Severe MS & AS
38. BRADYCARDIA
•Defined as HR < 50 beats/ min.
•T1-4 involvement leads to unopposed vagal tone and
decreased venous return which leads to bradycardia
and asystole
NAUSEA AND VOMITING
Causes(Hypotension, Increased peristalsis, Opioid
analgesia)
Nausea and vomiting may be associated with
neuraxial block in up to 20% of patients,
atropine is almost universally effective in treating the
nausea associated with high (T5) neuraxial anesthesia.
Complications
39. CRANIAL NERVE PALSY
TRANSIENT NEUROLOGICAL SYMPTOM (More
common with lidocaine)
CAUDA EQUINA SYNDROME (Bowel-bladder
dysfunction)
HIGH NEURAL BLOCKADE :
Excessive dose, failure to reduce standard
dose[elderly, pregnant, obese, very short stature]
Unconsciousness, hypotension, apnea is
referred to as high spinal or total spinal
40. HYPOTENSION
Prevented by: Volume loading with 10-20 mL/kg of
intravenous fluid
Predictors of hypotension
low intravascular volume in case of hypovolemia due
external loss by trauma, dehydration, internal loss
sensory block ≥ T5
age > 40 years
systolic BP < 120 mm Hg
combined spinal and general anesthesia
dural puncture between L2-3 and above
emergency surgery
pt with h/o uncontrolled hypertension
underlying autonomic dysfunction
41. Treatment of hypotension
100% O2
Elevation of leg .
Head down position
FLUIDS-
crystalloid
Colloid [500-1000ml] preferred due to increased
intravascular time, maintaining CO, uteroplacental
circulation.
43. Total Spinal
Management of total spinal
•Airway - secure airway and administer 100%
oxygen
•Breathing - ventilate by facemask and intubate.
•Circulation - treat with i/v fluids and vasopressor
e.g. ephedrine 3-6mg or metaraminol 2mg
increments or 0.5-1ml adrenaline 1:10 000 as
required
•Continue to ventilate until the block wears off (2 -
4 hours)
•As the block recedes the patient will begin
recovering consciousness followed by breathing and
then movement of the arms and finally legs.
44. Post Dural Puncture Headache:
Due to leak of CSF from dural defect leads to traction in
supporting structure especially in dura and tentorium &
vasodialatation of cerebral blood vessels.
Usually bifrontal and or occipital, usually worse in
upright , coughing , straining
Causes nausea, photophobia, tinnitus, diplopia[6th nerve],
cranial nerve palsy
Treatment plan include keeping patient supine,
adequate hydration, NSAIDS with without caffeine
[increases production of csf and causes vasoconstriction
of intracranial vessels], if not relieved within 12-24 hr
then epidural blood patch.
Epidural blood patch consists of giving 20 ml
45. Factors that May Increase the Incidence of Post–spinal Puncture Headache
Age Younger more frequent
Gender Females > males
Needle size Larger > smaller
Needle bevel
Less when the needle bevel is placed in the
long axis of the neuraxis
Pregnancy More when pregnant
Dural punctures (no.) More with multiple punctures
Factors Not Increasing the Incidence of Post–spinal Puncture Headache
Continuous spinals
Timing of ambulation
Relationships Among Variables and Post–spinal
Puncture Headache
Onset of headache :Usually 12-72 h following the procedure
46. Epidural Anesthesia
Local anaesthetic solutions are deposited in the
peridural space between the dura mater and the
periosteum lining the vertebral canal. The peridural
space contains adipose tissue, lymphatics and blood
vessels. The injected local anaesthetic solution
produces analgesia by blocking conduction at the
intradural spinal nerve roots.
47. Epidural Anesthesia continue
Technique:
Loss of resistance technique to identify the epidural
space.
0.5% Bupivacaine (mainly) or lidocaine (2.0%) is
usually used to produce epidural anaesthesia.
48.
49. Epidural Anesthesia continue
Indication and Contraindication:
The same of spinal anaesthesia.
Additional indication is the post operative Pain
management using the epidural catheter technique.
Complications: the same of spinal anaesthesia,
except the post dural puncture headache.
50. Differences between Spinal and Epidural
Anesthesia
Spinal anaesthesia
Level: below L1/L2, where the
spinal cord ends
Injection: subarachnoid space i.e
punture of the dura mater
Identification of the
subarachnoid space: When CSF
appears
Dosis: 2.5- 3.5 ml bupivacaine
0.5% heavy
Onset of action: rapid (2-5 min)
Density of block: more dense
Hypotension: rapid
Headache: is a probably
complication
Extradural Anaesthesia
Level: at any level of the
vertebral column.
Injection: epidural space
(between Ligamentum flavum
and dura mater) i.e without
punture of the dura mater
Identification of the Peridural
space: Using the Loss of
Resistance technique.
Doses: 15- 20 ml bupivacaine
0.5%
Onset of action: slow (15-20
min)
Density of block: less dense
Hypotension: slow
Headache: is not a probable.
51. References
Miller’s Anesthesia, 6th edition.
Morgan Anesthesia 4th edition.
Textbook of regional Anesthesia & Pain MX; By
Prithviraj
Baras Clinical Anesthesia
Neuraxial Anesthesia by D.E. Longnecker et al
New York: McGraw-Hill Medical.
Wylie Anesthesia
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