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Inhalational anaesthetic agents

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The document discusses the history of inhalational anesthetic agents and the concept of minimum alveolar concentration (MAC). It describes how MAC was defined by Eger in the 1960s as the concentration of an inhaled anesthetic that prevents movement in 50% of subjects exposed to a painful stimulus. MAC allows comparison of potency between agents and provides a standard measure. Factors like age, drugs, and medical conditions can impact MAC values.

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INHALATIONAL ANAESTHETIC AGENTS History & Minimum alveolar concentration Presenter: Dr.Anoop Kumar Moderator:Dr.Anand Kulkarni
History ,[object Object],[object Object],[object Object],[object Object]
History Contd .. ,[object Object],[object Object]
 
History contd… ,[object Object],[object Object]
History contd… ,[object Object],[object Object]
History contd… ,[object Object],[object Object],[object Object]
Minimum Alveolar concentration (MAC) ,[object Object],[object Object]
Determination of MAC ,[object Object],[object Object]
MAC Contd… ,[object Object],[object Object],[object Object]
MAC Contd… ,[object Object],[object Object],[object Object]
MAC contd.. ,[object Object],[object Object]
MAC Awake ,[object Object],[object Object],[object Object],[object Object]
MAC Bar ,[object Object],[object Object]
MAC Rationale Why this measures anaesthetic potency? ,[object Object],[object Object],[object Object]
Factors supporting use of MAC ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],Factors affecting MAC MAC
Factors sing MAC contd… ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Drugs MAC
Factors MAC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
No changes in MAC ,[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical implications of MAC ,[object Object],[object Object],[object Object],[object Object]
MAC of common inhalational anaesthetics 2 Sevoflurane 1.2 Isoflurane 0.75 Halothane 105 N2O 1.6 Enflurane
Thank you

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Inhalational anaesthetic agents

  • 1. INHALATIONAL ANAESTHETIC AGENTS History & Minimum alveolar concentration Presenter: Dr.Anoop Kumar Moderator:Dr.Anand Kulkarni
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  • 23. MAC of common inhalational anaesthetics 2 Sevoflurane 1.2 Isoflurane 0.75 Halothane 105 N2O 1.6 Enflurane