The document summarizes a study on the effect of preemptive gabapentin on postoperative pain and opioid requirement following head and neck surgeries. The study involved 60 patients divided into a gabapentin group and a control group. Pain scores and opioid requirements were significantly lower in the gabapentin group compared to the control group over 24 hours post-surgery. Heart rate, blood pressure and nausea were also lower in the gabapentin group. The study concludes that preemptive gabapentin effectively reduces postoperative pain and opioid needs following head and neck surgeries.

1. The Effect Of Preemptive Gabapentin On Postoperative Pain And Opioid Requirement Following Head And Neck Surgeries Dr Nikhil M P Dr N R Bhat Dr Prashanth mallya Dr Ambareesha M

15. Intergroup comparison of pain scores postoperatively for 24 hours following surgery at different time intervals Time Group N Mean Std.deviation t p value 0-6 Control Case 30 30 3.16 1.69 0.34 0.47 13.8 p=0.001 7-12 Control Case 30 30 2.35 2.05 0.67 0.53 2.094 p=0.041 13-18 Control Case 30 30 1.85 1.45 0.76 0.53 2.4 p=0.019 19-24 Control Case 30 30 1.39 1.003 0.76 0.40 2.5 p=0.015

16. Intergroup comparison of pain scores postoperatively for 24 hours at different time intervals

17. Intergroup comparison of pethidine requirement postoperatively for 24 hours Groups N Mean Std.deviation Z Control 30 163.16 39.7 6.67 Case 30 47.00 23.5 p=0.001

18. Intergroup comparison of pethidine requirement postoperatively for 24 hours

19. Intergroup comparison of heart rate postoperatively for 24 hours Time Group N Mean Std. deviation t P value 0 -6 control case 30 30 90.2 79.7 6.96 4.9 6.74 P=0.001 7-12 control case 30 30 88.46 75.86 6.5 4.9 8.41 P=0.001 13-18 control case 30 30 84.5 71.5 5.4 4.8 9.76 P=0.001 19-24 control case 30 30 79.7 69.5 8.19 4.006 6.26 P=0.001

20. Intergroup comparison of SBP postoperatively for 24 hours Time Group N Mea n std. deviation t p value 0-6 control case 30 30 139.8 131.2 9.03 5.18 4.52 p=0.001 7-12 control case 30 30 137.6 129.0 8.77 3.14 5.09 p=0.001 13-18 control case 30 30 134.1 125.3 8.51 4.43 5.01 p=0.001 19-24 control case 30 30 131.8 121.2 8.37 3.87 4.51 p=0.001

21. Intergroup comparison of DBP postoperatively for 24 hours Time Group N Mea n std. deviation t p value 0-6 control case 30 30 82.4 80.06 4.28 1.33 2.9 p=0.005 7-12 control case 30 30 82.2 79.9 5.12 1.23 2.41 p=0.019 13-18 control case 30 30 81.8 79.5 4.75 1.25 2.6 p=0.012 19-24 control case 30 30 81.06 78.4 5.1 3.37 2.35 p=0.022

22. Intergroup comparison of nausea postoperatively for 24 hours

23. Intergroup comparison of nausea postoperatively for 24 hours