This document provides information about nurse practitioners (NPs) and independent nurse practice (INP). It defines NPs as registered nurses who have graduate-level nursing education and can diagnose, treat, and prescribe medications within their scope of practice. INPs are registered nurses who provide healthcare services independently. The document discusses the history and development of the NP role in the US since the 1960s. It also outlines the education, certification, and scope of practice of NPs in different specialties. Challenges to the NP and INP roles are mentioned, as well as strategies to address them through legislation, guidelines, and adherence to professional and legal standards.