Right Paratracheal Stripe
Posterior wall of the bronchus intermedius
Left Paratracheal Stripe
Left subclavian artery border
Posterior-superior junction line
Right Paratracheal Stripe
Posterior wall of the bronchus intermedius
Left Paratracheal Stripe
Left subclavian artery border
Posterior-superior junction line
USMLE RESP 03 larynx anatomy medical respiratory .pdfAHMED ASHOUR
The larynx, commonly known as the voice box, is a cartilaginous structure located in the neck, connecting the pharynx (throat) to the trachea (windpipe).
It plays a crucial role in phonation (production of sound) and protecting the lower respiratory tract.
Disorders of the larynx can impact speech and swallowing.
Conditions such as laryngitis, vocal cord nodules, or laryngeal cancer can affect the structure and function of the larynx. Voice changes, difficulty swallowing, and respiratory compromise are common symptoms associated with laryngeal disorders.
DR RAJ BUMIYA'S THYROID LESIONS USG - ULTRASONOGRAPHYRaj Bumiya
MOB NO. 09978345496 ULTRASONOGRAPHY FEATURES OF NORMAL ANATOMY OF THYROID , CHARACTERISTICS OF VARIOUS NODULAR AND DIFFUSE THYROID DISEASES ( LESIONS )
Comparison between ct mri in ischemic stroke AHMED ESAWY
Comparison between ct MRI in ischemic stroke .1-Definition
2-Pathology
3-Vascular territory
4-Staging
5-hemorrhagic transformation of the infarct
Difference between simple hemorrhage and hemorrhagic neoplasm
difference between Hemorrhagic infarct and primary intracerebral hemorrhage
6-Comparison between CT/MRI
7-CTA, MRA
8-Fogging
9-Pseudonormalization
10-Protocol
11-Differential diagnosis
12-home message
All thing breast ultrasound breast mammography part 3AHMED ESAWY
All thing breast ultrasound breast mammography part 3
Breast mammogram ultrasound lipoma ,oil cyst ,galactocele intramammary lymph node in UOQ hamartoma Simple cyst (typical) calcification Surgical scar Breast implants, scirrhuc carcinoma lobular carcinoma Skin calcifications vascular calcifications Sutural Dystrophic popcorn Large Rod like rim Round/punctuate Fat necrosis Milk of calcium Fibrocystic FCC fibroadenosis Fat necrosis with oil cyst mastitis with Abscess Haematoma atypical ductal hyperplasia Intracystic papilloma ductal carcinoma in situ ,invasive ductal carcinoma BIRAD
All thing breast ultrasound breast mammography part 1AHMED ESAWY
All thing breast ultrasound breast mammography part 1
Breast mammogram ultrasound lipoma ,oil cyst ,galactocele intramammary lymph node in UOQ hamartoma Simple cyst (typical) calcification Surgical scar Breast implants, scirrhuc carcinoma lobular carcinoma Skin calcifications vascular calcifications Sutural Dystrophic popcorn Large Rod like rim Round/punctuate Fat necrosis Milk of calcium Fibrocystic FCC fibroadenosis Fat necrosis with oil cyst mastitis with Abscess Haematoma atypical ductal hyperplasia Intracystic papilloma ductal carcinoma in situ ,invasive ductal carcinoma BIRAD
Update secrets in plain x ray abdomen gases ,air fluid level .AHMED ESAWY
plain x-ray abdomen gas normal air fluid level in-the-abdomen gasless abdomen small bowel obstruction large intestinal obstruction ileus gastric dilatation extraluminal abdomen gas (pneumonpperitoneum) extraluminal abdomen gas(retropneumonpperitoneum gas in specific organs (hepatobiliary ,genitourinary) gasless abdomen ‘step-ladder apperance stretch/slit sign string of pearls sign coiled spring sign small-bowel feces sign disproportionate dilatation of sb gallstone ileus intussusception caecal volvulus sigmoid volvulus colonic pseudo obstruction ogilvie syndrome acute colitis toxic megacolon ischemic colitis sentinel loops intestinal pseudo-obstruction syndromes gastric volvulus organoaxial gastric volvulus mesenterico-axial right upper quadrant gas crescent sign: air beneath the diaphragm peri hepatic sub hepatic morrison’s pouch fissure for ligament teres doges cap sign rigler’s (double wall sign) ( both the serosal and the related mucosal walls of the bowel are delineated it means free air is at that serosal surface ) ligament visualization falciform ligament sign: air delineating the falciform ligament umbilical inverted ‘v’ sign triangular air cupola sign football sign or air dome (a large air collection beneath that does not confirm to any bowel loop) continous diaphragm sign scrotal air in children decubitus abdomen sign double bubble sign lesser sac sign peritonitis postoperative pelvic and spinal fractures
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Larynx Imaging 4th part virtual laryngoscopy vocal cord paralysis CT MRI Dr Ahmed Esawy
1. CTVL (CT virtual laryngoscopy)
is a new method for
demonstrating the endoluminal
structures of the laryngeal and
hypopharyngeal region
simulating actual laryngoscopy.
8. • CT in Carcinoma of the
Larynx and Pyriform
Sinus:Value of Phonation
Scans
9. • A, CT scan in normal subject during quiet breathing at level of true vocal
cords. Arytenoid cartilages (arrows) cleanly visible in close proximity to inner
margin of thyroid cartilage. Right anytenoid slightly larger than left.
• B, During phonation of letter E, arytenoid cartilages adduct and
rotateinwards. Distended pyniform sinuses (P) are seen lateral to arytenoid
cartilages.
10. • A, Scan during quiet breathing at level of true vocal
cords in patient with clinical fixation of right true cord.
Cordal mass (arrows) displaces vocal process of right
arytenoid cartilage medially.
• B, During phonation. Left anytenoid moves normally.
Right arytenoid remains fixed in abducted position.
11. •RULE OF CT in the
Diagnosis of Vocal
Cord Paralysis
12. VOCAL CORD PARALYSIS
• Etiology:
• Causes of vocal cord paralysis may be divided as:
• A) Congenital:
• For example; nuclear aplasia, cerebral agenesis, birth trauma, stretch at the
skull base in meningioceles and hydrocephalus (Arnold-Chiari malformation).
• B) Acquired: These include:
• 1. Trauma:
• Surgical trauma: is the most common cause of vocal cord paralysis (25%). The
most common surgery is thyroid surgery. Other operations include; radical neck
dissection, carotid artery surgery, oesophageal surgery, cardiac surgery and
mediastinal surgery.
• Accidental trauma: as gunshots and stab wounds to the neck or chest.
• 2. Neoplasms:
• As bronchogenic carcinoma (most common). esophageal and postcricoid
carcinoma and thyroid tumors.
• 3. Systemic disorders:
• Infections: Viral (as influenza), or bacterial (TB, or syphilis)
• Toxic neuritis: Diabetes, lead and alcohol poisoning.
• Cardiovascular: Cardiomegally e.g. in mitral stenosis, and aortic aneurysm.
• 4. Idiopathic
13. CT signs of cord paralysis
• paramedian position of the cords,
• displaced arytenoid cartilage,
• ipsilateral dilatation of the pyriform sinus,
• tilting of the thyroid cartilage,
• medial positioning and thickening of the ipsilateral
aryepiglottic fold,
• ipsilateral laryngeal ventricle dilatation
• Ipsilateral pharyngeal constrictor muscle atrophy
• peripheral and central vagal neuropathy
14. • Usefulness of Laryngeal
Phonation CT in the Diagnosis of
Vocal Cord Paralysis
16. -distance between cord tip
and
midline of laryngeal
airway
during phonation.
-Black arrows indicate
stretched
vocal cord during
phonation.
-Angle between long axis
of the vocal cord and
midlline Dr Ahmed Esawy
17. A —29-year-old
woman in good health.
Coronal reconstructed
• CT image of larynx during
normal breathing shows larynx at
level of vocal cords appears to
be flat, without vocal cord
protrusion.
B- during phonation
protrude,symmetrical
Dr Ahmed Esawy
18. • Fig. A —65-year-old woman with left vocal
cord paralysis for 2 years. Coronal
reconstructed CT image of larynx during
normal breathing shows relaxed
appearance of both vocal cords without
protrusion (arrows).
Dr Ahmed Esawy
19. • Using CT to Localize Side and
Level of Vocal Cord Paralysis
20. dilatation of right vallecula (arrow, A) and
dilatation of right pyriform sinus (A),
dilatation of right pyriform sinus and
thickening and medial positioning of right
aryepiglottic fold
and dilatation of right
laryngeal ventricle (white
arrow
and anterior positioning of right
arytenoid cartilage (black arrow, C).
Dr Ahmed Esawy
21. dilatation of right vallecula
dilatation of right pyriform sinus and
thickening and medial positioning of right
aryepiglottic fold
fullness of right true vocal cord and slight
anterior positioning of right arytenoid
cartilag
right subglottic fullness
Dr Ahmed Esawy
22. dilatation of right pyriform sinus (large
arrow, A), thickening and medial
positioning of left aryepiglottic fold (small
arrow, A
dilatation of left laryngeal ventricle
(arrow)
ullness of right true vocal cord Dr Ahmed Esawy
23. dilated left oropharynx with thinning and
atrophy of pharyngeal wall (arrow)
dilatation of left pyriform sinus and
thickening and medial positioning of left
aryepiglottic fold
64-year-old man with hoarseness, left
vocal cord paralysis, and left-sided palatal
weakness CT+C
25. 1-STRIDOR
• Definition: Difficult noisy breathing
due to partial laryngeal obstruction.
Early it is inspiratory, later it
becomes both inspiratory and
expiratory when obstruction
increases.
26. Causes of stridor ( laryngeal
obstruction ):
• Congential :
• Congenital web .
• Congenital laryngeal stridor :
• Infantile larynx.
• Congenital laryngomalacia.
• Traumatic :
• Foreign body .
• Accidental trauma:
• External Trauma e.g cut throat or strangulation
• Internal trauma:
• Chemical e.g corrosives.
• Physical e.g hot water or burns.
• surgical trauma ( Iatrogenic ):
• I – Immediate: e.g oedema following endoscopy or difficult endotracheal intubation.
• II – Late: e.g stenosis following high tracheostony or prolonged endotracheal intubation.
• Inflammatory :
• Acute:
• Non specific : in children .
• Specific : diphtheria .
• Chronic:
• I- Non specific : only with acute exacerbation
• II- Specific : Scleroma , syphilis , T.B .
• Allergic oedema :
• e.g angioneurotic oedema or durg sensitivity e.g. to penicillin
• Neoplastic :
• Benign: multiple popillomatata in childern.
• Malignant: carcinoma.
• Neurogenic :
• Bilateral abductor paralysis : most commonly after thyroidectomy.
• Functional
• Laryngismus stridulus
27. 2-HOARSENESS OF VOICE:
• Definition: Rough, harsh quality to
voice or cry.
• Causes: Lesions in the true vocal
cords.