The nervous system and brain work to maintain homeostasis through automatic and voluntary responses. The brain controls the nervous system and regulates physiological processes like temperature, hunger, and sleep. The brain also helps regulate the endocrine system, which produces hormones that stimulate processes to maintain homeostasis. Hormones are transported via the bloodstream and target specific cells, like kidney cells, to signal processes like water reabsorption during dehydration. Feedback systems with both positive and negative feedback help regulate body responses to internal and external changes to maintain homeostasis.