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 It circulates blood &
lymph;
◦ 1. Blood vascular system
(Cardiovascular system)
◦ Heart + blood vessels
(arteries, capillaries,
veins)
◦ 2. Lymph vascular system
◦ Lymph capillaries,
lymphatic vessels,
lymphatic ducts
 Most of the tissue fluid formed at
the arterial end of capillaries is
absorbed back into the blood by
the venous ends of the capillaries
and the post-capillary venules.
 The rest of the tissue fluid (10-
20%) is absorbed by the lymphatics
which begin blindly in the tissue
spaces.
 LYMPH: The tissue fluid flowing
in the
lymphatics
 Lymph is clear and colorless
 CHYLE & LACTEALS: Lymph From
small intestine it is milky-white due
to absorption of fat & is called chyle,
and lymph vessels, the lacteals.
The lymph capillaries join to form lymphatics,
The lymph passes through filters or barriers of the regional
lymph nodes which trap the particulate matter.
The filtered lymph passes through larger lymphatics
collected into two large trunks  the thoracic and right
lymphatic duct,
which pour their lymph into the veins
Thoracic duct drains both lower limbs, abdomen, left
halves of thorax, head and neck and left upper limb.
Right lymphatic duct drains  right halves of thorax, head
and neck and right upper limb.
 Lymph vessels
1. lymph capillaries join to form lymphatics,
2. larger lymphatics eventually collected into two large
3. trunks, the thoracic duct and right lymphatic duct
 Central lymphatic tissue
1. bone marrow
2. Thymus
 Peripheral lymphatic tissue
1. lymph nodes
2. spleen
3. epithelio-lymphoid tissues
 Circulating lymphocytes
 1. In blood about 70% of circulating lymphocytes are T cells,
 2. 15% are B cells and
 3. 15% are natural killer (NK) cells.
 Delicate endothelial tubes originates
from tissues as blind ended vessels.
 Larger lumen than blood capillaries
 Form network in spaces between
blood capillaries
 Lined by single layer of endothelial
cells (squamous)
 Special feature
 Basal lamina is incomplete
 Intercellular clefts b/w endothelial
cells
 Capillaries lined by endothelial cells single
layer
 Basal lamina is incomplete
 Intercellular cleft between endothelial cells
 allow entry of macromolecules(proteins,
fat in intestine) from interstitial fluid
 From surrounding C.T anchoing filaments
of elastin extends in basal lamina to
maintain the patency of Intercellular cleft
 Overlapping of endothelial cells results in
valve formation which prevents the back
flow
 Walls are thinner than veins
 Larger lymphatics  3 layers
◦ Tunica intima, media, adventitia
 Tunica intima: endothelium + basal lamina 
elastic, collagen fibers
 Tunica media: Smooth ms: fibers (circularly
arranged) + elastic fibers
 Tunica Adventitia: thickest coat
 Collagen+ elastic fibers+ few sm ms:
longitudinal arranged
 Similar in structure of same size vein but > Sm ms in
T.M
 Tunica Intima: endothelium
◦ Sub-endothelial layer: C.T + few Sm: ms:
fibers
◦ Internal elastic lamina also distinguishable
 Tunica media: thickest coat
 Smooth muscle fibers (circular & longitudinally
arranged)+ C.T  Collagen
 Tunica adventitia: collagen fibers+ few sm ms fibers
Histology of lymphatic vessels
Histology of lymphatic vessels
Histology of lymphatic vessels
Histology of lymphatic vessels
Histology of lymphatic vessels
Histology of lymphatic vessels

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Histology of lymphatic vessels

  • 1.
  • 2.  It circulates blood & lymph; ◦ 1. Blood vascular system (Cardiovascular system) ◦ Heart + blood vessels (arteries, capillaries, veins) ◦ 2. Lymph vascular system ◦ Lymph capillaries, lymphatic vessels, lymphatic ducts
  • 3.  Most of the tissue fluid formed at the arterial end of capillaries is absorbed back into the blood by the venous ends of the capillaries and the post-capillary venules.  The rest of the tissue fluid (10- 20%) is absorbed by the lymphatics which begin blindly in the tissue spaces.
  • 4.  LYMPH: The tissue fluid flowing in the lymphatics  Lymph is clear and colorless  CHYLE & LACTEALS: Lymph From small intestine it is milky-white due to absorption of fat & is called chyle, and lymph vessels, the lacteals.
  • 5. The lymph capillaries join to form lymphatics, The lymph passes through filters or barriers of the regional lymph nodes which trap the particulate matter. The filtered lymph passes through larger lymphatics collected into two large trunks  the thoracic and right lymphatic duct, which pour their lymph into the veins Thoracic duct drains both lower limbs, abdomen, left halves of thorax, head and neck and left upper limb. Right lymphatic duct drains  right halves of thorax, head and neck and right upper limb.
  • 6.
  • 7.
  • 8.  Lymph vessels 1. lymph capillaries join to form lymphatics, 2. larger lymphatics eventually collected into two large 3. trunks, the thoracic duct and right lymphatic duct  Central lymphatic tissue 1. bone marrow 2. Thymus  Peripheral lymphatic tissue 1. lymph nodes 2. spleen 3. epithelio-lymphoid tissues  Circulating lymphocytes  1. In blood about 70% of circulating lymphocytes are T cells,  2. 15% are B cells and  3. 15% are natural killer (NK) cells.
  • 9.
  • 10.
  • 11.
  • 12.  Delicate endothelial tubes originates from tissues as blind ended vessels.  Larger lumen than blood capillaries  Form network in spaces between blood capillaries  Lined by single layer of endothelial cells (squamous)  Special feature  Basal lamina is incomplete  Intercellular clefts b/w endothelial cells
  • 13.  Capillaries lined by endothelial cells single layer  Basal lamina is incomplete  Intercellular cleft between endothelial cells  allow entry of macromolecules(proteins, fat in intestine) from interstitial fluid  From surrounding C.T anchoing filaments of elastin extends in basal lamina to maintain the patency of Intercellular cleft  Overlapping of endothelial cells results in valve formation which prevents the back flow
  • 14.
  • 15.  Walls are thinner than veins  Larger lymphatics  3 layers ◦ Tunica intima, media, adventitia  Tunica intima: endothelium + basal lamina  elastic, collagen fibers  Tunica media: Smooth ms: fibers (circularly arranged) + elastic fibers  Tunica Adventitia: thickest coat  Collagen+ elastic fibers+ few sm ms: longitudinal arranged
  • 16.
  • 17.
  • 18.  Similar in structure of same size vein but > Sm ms in T.M  Tunica Intima: endothelium ◦ Sub-endothelial layer: C.T + few Sm: ms: fibers ◦ Internal elastic lamina also distinguishable  Tunica media: thickest coat  Smooth muscle fibers (circular & longitudinally arranged)+ C.T  Collagen  Tunica adventitia: collagen fibers+ few sm ms fibers