Hepatoblastoma is a rare liver tumor that affects children under 3 years old. It starts as a golf ball-sized tumor in the right lobe of the liver. Genetic disorders like Beckwith-Wiedemann syndrome and familial adenomatous polyposis can cause hepatoblastoma. Symptoms include abdominal swelling, weight loss, and jaundice. Treatment depends on the stage - early stage tumors can be surgically removed while later stages involve chemotherapy and then surgery. Without treatment, stage 4 hepatoblastoma is fatal.

2.  Hepatoblastoma only affects children of 3
years or younger.
 Hepatoblastoma is a tumor that originates in
the liver or gallbladder and has a potential to
spread to any other organs causing multiple
kinds of cancer.
 This disorder always starts out as a golf ball
sized tumor on the right lobe of the liver.
 At around 18 months is when it starts.
 100 cases reported of this disorder each year.

3.  Many genetic disorders can lead to having
Hepatoblastoma instead of the original
disorder.
 The main two genetic disorders that lead to
this disease Beckwith-Wiedemann syndrome
and familial adenomatous polyposis
 This can be passed to the child through
unknown recessive genes.

4. The most common
symptoms include:
A large abdominal mass, or
swollen abdomen
Weight loss
Decreased appetite
Abdominal pain.
Vomiting.
Jaundice – yellowing of eyes or
skin.
Fever
Itching Skin
Anemia – pale skin and lips from
decreased number of red blood
cells.
Back pain from compression of
the tumor.
This picture shows
how big the
abdomen can get.

5. The only “prevention”
is to see if you have
the recessive genes
either the disease
itself or the other
diseases that causes
it.
If you find out that
you have the mutated
genes then the best
thing to do is to not
have children.

6. Treatment depends on what
stage the tumor is at
Stage 1: Easily and completely
removed tumor.
Stage 2: Removed with a little
bit of the tumor left, which is
inactive because of a small
amount of chemotherapy.
Stage 3: Can’t be removed by
surgery alone, must have
chemotherapy to decrease the
size of the tumor, then the
tumor gets removed,
Stage 4: No treatment, 100%
fatal This is around a Stage 4
The tumor
has
completely
consumed the
right half of
the liver in
this picture.
This is usually
what stage
three looks
like.