1) HBV is a partially double-stranded DNA virus that was discovered in the 1960s and can cause both acute and chronic hepatitis B infections. 2) It is transmitted through bodily fluids and can be diagnosed through serological and molecular testing for antigens and antibodies. 3) Vaccination provides effective immunization against HBV infection and treatment options for chronic infection include immunomodulators and nucleoside/nucleotide analogs.