An absolute eosinophil count is a blood test that measures the number of one type of white blood cells called eosinophils.
Eosinophils become active when you have certain allergic diseases, infections, and other medical conditions.
An absolute eosinophil count is a blood test that measures the number of one type of white blood cells called eosinophils.
Eosinophils become active when you have certain allergic diseases, infections, and other medical conditions.
This presentation is focused on diagnostic utility of Red blood cell indices which will be very useful for undergraduate and postgraduate of medical field.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
1. Hematology analyzer
• Channels
• Overview of analysis modes
• Handling abnormal results
1
Diagnostic Hematology - Dr.Alagbare
BACK to
contentDeveloped by-Dr.Abdulrazzaq Othman Alagbare
M.D M.S.c C.P - Lecturer of Hematology and Immunohematology
Hematology analyzer -Chanels-Modes- Handling abnormal results
Errors
2. 2
Hematology analyzer Channels
Channel for Red blood cells and platelets analyzing ,
RBCs and platelets using the same dilution
Channel for WBC and hemoglobin measurement:
Lytic agents lyse red cells first before analysis.
Channel for WBC differential count.
Channel for Reticulocyte count.
Diagnostic Hematology - Dr.Alagbare
3. 3
Other channels:
A. nucleated red blood cell (NRBC) channel,
B. separate hemoglobin (Hb) channel,
C. WBC/basophil counting channel,
D. and immature granulocyte counting channel.
Diagnostic Hematology - Dr.Alagbare
4. Small volume of EDTA blood
sample is aspirated and diluted
in an electrically conductive
diluent.
1. RBC/PLT chamber
2. WBC/Hgb chamber
• RBCs lysed, Hgb directly
measured by spectrophotometry
and WBCs counted
1. Mixing chamber – differential
2. Reticulocyte dilution chamber
4
Diagnostic Hematology - Dr.Alagbare
5. 5
In the channel of RBC/PLT counting
• Particles between 2 and 20 fL are counted as
platelets,
• and particles larger than 35 fL are counted as
RBCs.
Diagnostic Hematology - Dr.Alagbare
They fall in the overlap area between platelets
and RBCs, generating a warning flag.
Why
6. Errors in platelet counts
6
Falsely high platelet
counts
Microcytic red cells
Red cell fragments
White cell fragments of
leukaemic blast cells
Contaminated blood
sample (Bacteria Malaria,
fungus)
7. 7
Microcytic red cells that notched in IDA,
if the RBC have very low volume fall in the platelets counting zone
and they counted as platelets,
for that we have slight increase of platelets count in IDA
10. Needs 30-40 µl
This is the mode of analyzing collected blood sample in the
whole blood status
10
USES
For Paediatric specimens.
This mode is used in analyzing a minute amount of child’s
blood, for example, collected from the earlobe or fingertip.
Diagnostic Hematology - Dr.Alagbare
Overview of analysis modes
1-Whole blood mode
2-Pre-diluted mode
HOW?
In this mode, blood sample diluted into 1:26 before
analysis is used.
The sample aspiration procedure is the same as in the
whole blood mode.
11. 1-Plts < 40,000
How solved?
1. Check the integrity of the specimen (look for clots, short draw, etc.)
2. Confirm count
with smear review for clumps, RBC fragments, giant platelets, very small RBCs
HANDLING ABNORMAL RESULTS
11
Diagnostic Hematology - Dr.Alagbare
12. 2-Plt ++++
How solved?
HANDLING ABNORMAL RESULTS
12
Diagnostic Hematology - Dr.Alagbare
If present,
o perform plt. estimate.
o If they do not agree, perform
manual plt count.
If not present,
o dilute specimen 1:2 with Isoton or
further until count is within linearity,
multiply diluted result by dilution
factor.
Do PBS
Check smear for RBC
fragments or microcytes.
13. Diagnostic Hematology - Dr.Alagbare
13
CASE
A 44-year-old woman comes in for a complete blood count (CBC) as part of a routine physical exam. The
results from the hematology analyzer,, are:
PLEASE answer the following
1. What is abnormal about her CBC?
2. Which parts can be reported?
3. What procedures can be done regarding the abnormal result?
4-Which cells included in MID and Gran?
14. 14
Questions
1. What is abnormal about the blood count?
2. Which parts of the CBC can be reported?
3. What would you do to investigate the
abnormal result?
4-write the situation which cause low false
PLT count?
15. Diagnostic Hematology - Dr.Alagbare
15
1 2
3
Answer the following
What called each image?
Describe and write a small paragraph for each image how developed, and what effect on the platelets count?
How solved each problem of them if present?
16. 3-WBC ++++
How solved?
Dilute 1:2 with Isoton or further until count is within linearity (for final result,
multiply diluted result by dilution factor.
Plt counts are not affected by high WBC.
Add comment, “Unable to report Hgb, MCH, MCHC due to high WBC.”
HANDLING ABNORMAL RESULTS
16
Diagnostic Hematology - Dr.Alagbare
17. 17
In some printouts use the following symbols
UWBC represents uncorrected WBC count
WBC represents corrected WBC count
In some printouts use the following symbols
“&”WBC represents corrected WBC count
Plt & represents corrected PLT count
Diagnostic Hematology - Dr.Alagbare
19. HANDLING ABNORMAL RESULTS
4-RBC > 7.0
How solved?
1. Dilute 1:2 with Isoton or further until count is within linearity, multiply dilution
result by dilution factor;
2. perform spun Hct,
3. review Hgb,
4. recalculate MCH, MCHC
19
Diagnostic Hematology - Dr.Alagbare
20. 20
Normal White blood cells volume
Cells with volume Designated as
35-90 fl Lymphocytes,
90-160 fl Monocyte, Eos, BAS
160-450 Neutrophils,
Diagnostic Hematology - Dr.Alagbare