Health
Research
Dr. Ahlam Sundus
PharmD, M.Phil. (Malaysia)
Introduction to Health Research
Key questions:
What is a question?
What is a problem?
What is a research?
Why a research is conducted?
Who should be involved in research?
Basic questions in health system
• What are health needs of people?
• What is the coverage of health interventions?
• How can we use resources cost-effectively?
• How can we control environmental factors?
Without research answering these questions is
unthinkable
Health systems research
A systematic collection, analysis and interpretation
of health and health related data
to answer a certain question
or to solve a problem
Characteristics of research
• Demands clear statement of the problem
• Requires clear objectives & methods
• Builds on existing data
• Involves systematic process
• Have clear vision of outcome
Purposes of health research
• Basic research:
To generate new knowledge and technology
• Applied research:
It seeks to solve practical problems
It is used to find solutions to everyday problems, cure illness, and
develop innovative technologies
Quantitative Vs. Qualitative
Quantitative research:
Tries to quantify things in terms of numbers
Explanatory purpose
Qualitative research:
Tries to describe things in terms of contexts
Exploratory purpose
Guidelines for successful research
1. Focus on priority problems
2. Action-oriented
3. Multi-disciplinary
4. Participatory
5. Timely
6. Cost-effective
7. Simple, short-term designs
8. Clear results
9. Honest limitations
10. Expressed implications and recommendations
It is a must
It is a must for any research to be:
• Purposeful
• Targeted
• Credible
• Timely
METHODOLOGY
Study designs
Four major study designs
• Experimental
• Non-experimental
• Cross-sectional
• Case-control
• Cohort
• Selection of the study design depends on the
objective of a study
POPULATION
Target population: the population to whom
the results would be applied
• Source population: the population from
whom study subjects would be obtained
• Sample: Subjects who are selected
• Study subjects: the actual participants of
the study
Sampling techniques
1. Probability sampling
• Simple random
• Stratified random
• Systematic random
• Cluster sampling
• Multistage sampling
2. Non-probability sampling
• Purposive/Judgmental
• Convenience/Reliance
• Consecutive
• Snow ball
Study variables
A variable is a characteristic of a person, object
or phenomenon that can take on different
values expressed in numbers or categories.
Types of variables
1. Dependent/outcome/response variable
– Used to measure the problem under study
2. Independent/exposure/predictor variable
– Used to measure determinants of a
problem
3. Confounding variable
– A variable associated with both the
exposure and outcome
Statistical Procedures
Descriptive statistics
• Descriptive statistics try to describe the relationship
between variables in a sample or population
• It provides a summary of data in the form of mean,
median and mode
Inferential statistics
• Inferential statistics use a random sample of data taken
from a population to describe and make inferences
about the whole population
• It is valuable when it is not possible to examine each
member of an entire population
• Tests hypothesis
Understanding Inferential
Statistics
A hypothesis (plural hypotheses) is a proposed
explanation for a phenomenon. Hypothesis tests are
thus procedures for making rational decisions about
the reality of observed effects
Probability is the measure of the likelihood that an
event will occur
0 and 1
0 indicates impossibility and 1 indicates certainty
‘Null hypothesis’ (H0 ‘H-naught,’ ‘H-null’) denotes that
there is no relationship (difference) between the
population variables in question
Alternative hypothesis (H1 and Ha) denotes that a
statement between the variables is expected to be
true
The P value is the probability of the event occurring
by chance if the null hypothesis is true.
The P value is a numerical between 0 and 1 and
is interpreted by researchers in deciding whether
to reject or retain the null hypothesis
Measurement of variance
 Commonly used methods are
 Student’s t-test
 ANOVA test
 Students’t-test
Employed for comparing means of two
population
Significant difference between means of two
groups/variables
 ANOVA Test
The purpose of ANOVA is to test if there is any
significant difference between the means of two
or more groups
One-way ANOVA
 Determines variance between means
obtained from two different populations
Two-way ANOVA
 Analyze factor that interacts with the variables
under study along with analysis of variance
THANK
YOU

Health research

  • 1.
  • 2.
    Introduction to HealthResearch Key questions: What is a question? What is a problem? What is a research? Why a research is conducted? Who should be involved in research?
  • 3.
    Basic questions inhealth system • What are health needs of people? • What is the coverage of health interventions? • How can we use resources cost-effectively? • How can we control environmental factors? Without research answering these questions is unthinkable
  • 4.
    Health systems research Asystematic collection, analysis and interpretation of health and health related data to answer a certain question or to solve a problem
  • 5.
    Characteristics of research •Demands clear statement of the problem • Requires clear objectives & methods • Builds on existing data • Involves systematic process • Have clear vision of outcome
  • 6.
    Purposes of healthresearch • Basic research: To generate new knowledge and technology • Applied research: It seeks to solve practical problems It is used to find solutions to everyday problems, cure illness, and develop innovative technologies
  • 7.
    Quantitative Vs. Qualitative Quantitativeresearch: Tries to quantify things in terms of numbers Explanatory purpose Qualitative research: Tries to describe things in terms of contexts Exploratory purpose
  • 8.
    Guidelines for successfulresearch 1. Focus on priority problems 2. Action-oriented 3. Multi-disciplinary 4. Participatory 5. Timely 6. Cost-effective 7. Simple, short-term designs 8. Clear results 9. Honest limitations 10. Expressed implications and recommendations
  • 9.
    It is amust It is a must for any research to be: • Purposeful • Targeted • Credible • Timely
  • 10.
  • 11.
    Study designs Four majorstudy designs • Experimental • Non-experimental • Cross-sectional • Case-control • Cohort • Selection of the study design depends on the objective of a study
  • 12.
    POPULATION Target population: thepopulation to whom the results would be applied • Source population: the population from whom study subjects would be obtained • Sample: Subjects who are selected • Study subjects: the actual participants of the study
  • 13.
    Sampling techniques 1. Probabilitysampling • Simple random • Stratified random • Systematic random • Cluster sampling • Multistage sampling 2. Non-probability sampling • Purposive/Judgmental • Convenience/Reliance • Consecutive • Snow ball
  • 14.
    Study variables A variableis a characteristic of a person, object or phenomenon that can take on different values expressed in numbers or categories.
  • 15.
    Types of variables 1.Dependent/outcome/response variable – Used to measure the problem under study 2. Independent/exposure/predictor variable – Used to measure determinants of a problem 3. Confounding variable – A variable associated with both the exposure and outcome
  • 16.
    Statistical Procedures Descriptive statistics •Descriptive statistics try to describe the relationship between variables in a sample or population • It provides a summary of data in the form of mean, median and mode Inferential statistics • Inferential statistics use a random sample of data taken from a population to describe and make inferences about the whole population • It is valuable when it is not possible to examine each member of an entire population • Tests hypothesis
  • 17.
    Understanding Inferential Statistics A hypothesis(plural hypotheses) is a proposed explanation for a phenomenon. Hypothesis tests are thus procedures for making rational decisions about the reality of observed effects Probability is the measure of the likelihood that an event will occur 0 and 1 0 indicates impossibility and 1 indicates certainty
  • 18.
    ‘Null hypothesis’ (H0‘H-naught,’ ‘H-null’) denotes that there is no relationship (difference) between the population variables in question Alternative hypothesis (H1 and Ha) denotes that a statement between the variables is expected to be true The P value is the probability of the event occurring by chance if the null hypothesis is true.
  • 19.
    The P valueis a numerical between 0 and 1 and is interpreted by researchers in deciding whether to reject or retain the null hypothesis
  • 20.
    Measurement of variance Commonly used methods are  Student’s t-test  ANOVA test
  • 21.
     Students’t-test Employed forcomparing means of two population Significant difference between means of two groups/variables  ANOVA Test The purpose of ANOVA is to test if there is any significant difference between the means of two or more groups
  • 22.
    One-way ANOVA  Determinesvariance between means obtained from two different populations Two-way ANOVA  Analyze factor that interacts with the variables under study along with analysis of variance
  • 23.