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 INJECTION SITES
› Peripheral Vein
› Central Vein
 INFUSION METHODS
› Continuous Drip Infusion
› Intermittent Infusion
 I/VBOLUS
 ADDITIVE SET INFUSION
 PIGGYBAG METHOD
› Pumps
 VOLUMETRIC PUMP
 SYRINGE PUMP
 MOBILE INFUSION PUMP
 IMPLANTABLE PUMPS
 Controller
Electronically count the drops.
INFUSION PUMPS
SYRINGE PUMP
 PHYSICAL INCOMPATABILITY
› Visible change
 CHEMICAL INCOMPATABILITY
› Chemical degradation of admixed substance,
invisible.
› Complexation, oxidation, reduction, photolysis
 THERAPEUTIC INCOMPATABILITY
› Unintended outcomes
› Reduced antimicrobial activity
 pH
 Temperature
 Degree of dilution
 Length of time in solution
 Order of mixing
 Thorough mixing
 Prompt administration
 Minimum number to be admixed
 Consult for unfamiliar drugs
 Physical
› Phlebitis
› Thrombosis
› Extravasation
› Irritation
› Pain
› Air embolism
› Infection
› Allergic reaction
› Pneumothorax (central vein misplacement)
› Hypothermia
› Neurotoxicity (epidural)
 Mechanical hazards
› Controller/pump failure
› I/v tubing
› Particulate matter
› Glass containers
› Rubber vial enclosure
 Therapeutic hazards
› Drug instability
› Incompatibility
› Labeling error
› Drug overdose (fluid run away, pump failure)
› Preservative and solubilizing agent toxicity
Parenteral product containing benzyl alcohol cause
acidosis in infants
THANK YOU

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Intravenous hazards

  • 1.
  • 2.  INJECTION SITES › Peripheral Vein › Central Vein  INFUSION METHODS › Continuous Drip Infusion › Intermittent Infusion  I/VBOLUS  ADDITIVE SET INFUSION  PIGGYBAG METHOD
  • 3. › Pumps  VOLUMETRIC PUMP  SYRINGE PUMP  MOBILE INFUSION PUMP  IMPLANTABLE PUMPS  Controller Electronically count the drops.
  • 6.  PHYSICAL INCOMPATABILITY › Visible change  CHEMICAL INCOMPATABILITY › Chemical degradation of admixed substance, invisible. › Complexation, oxidation, reduction, photolysis  THERAPEUTIC INCOMPATABILITY › Unintended outcomes › Reduced antimicrobial activity
  • 7.  pH  Temperature  Degree of dilution  Length of time in solution  Order of mixing
  • 8.  Thorough mixing  Prompt administration  Minimum number to be admixed  Consult for unfamiliar drugs
  • 9.  Physical › Phlebitis › Thrombosis › Extravasation › Irritation › Pain › Air embolism › Infection › Allergic reaction › Pneumothorax (central vein misplacement) › Hypothermia › Neurotoxicity (epidural)
  • 10.  Mechanical hazards › Controller/pump failure › I/v tubing › Particulate matter › Glass containers › Rubber vial enclosure
  • 11.  Therapeutic hazards › Drug instability › Incompatibility › Labeling error › Drug overdose (fluid run away, pump failure) › Preservative and solubilizing agent toxicity Parenteral product containing benzyl alcohol cause acidosis in infants