Hand infection is the infection caused in hand , since hand contains neurovascular bundles, muscles, bones, and ligaments.
It includes
1. Acute Paronychia
2.Chronic Paronychia
3.Terminal pulp space infection ( felon)
4.subungal infection
5. Web space infecion
6. Mid palmar space infection
7.Thenar space infection
8. Deep palmar abscess
9. Acute suppurative tenosynovitis
11. Chronic Tenosynovitis
12. Lymphangitis of the hand
13. Arthritis of hand joints
14. Subcuticular abscess
Felon or Terminal Pulp Infection is defined as an abscess of pulp of finger. It may involve the terminal , middle or proximal pulp space, sometimes distal pulp space.
Gas gangrene, also known as clostridial myonecrosis, is an infective gangrene caused by clostridial bacteria such as Clostridium perfringens. It commonly occurs after trauma with open wounds or crush injuries that are contaminated. The bacteria release toxins and enzymes that break down muscle tissue, producing gas in the affected areas. Symptoms include pain, fever, and foul-smelling discharge from wounds. Treatment involves aggressive surgical debridement of dead tissue combined with high-dose intravenous penicillin antibiotics. Hyperbaric oxygen therapy may also be used as an adjuvant treatment. Without prompt treatment, gas gangrene can lead to sepsis, organ failure, and death.
This document discusses felon, an abscess of the pulp space in the finger. It notes that felon most commonly involves the distal pulp space of the index or thumb finger, resulting from minor trauma such as a finger prick. The pulp space contains fat partitions and becomes a closed compartment, so minor infections can lead to pus collection and increased pressure, compressing the terminal artery and potentially causing gangrene. Treatment involves antibiotics, drainage of the terminal pulp space through a longitudinal incision, and possible amputation of the terminal phalanx if osteomyelitis is present.
This document discusses abscesses, including:
1. An abscess is a collection of pus surrounded by inflamed tissues and contains dead and dying white blood cells and bacteria.
2. Abscesses spread along paths of least resistance and increase pressure, causing pain. They eventually burst spontaneously or require incision and drainage.
3. Treatment involves rest, elevation, antibiotics, and incision and drainage surgery to fully open and curette the abscess cavity.
Dr. Shalu Gupta provides a detailed overview of ulcers, including their definition, anatomy, classification, causes, examination, and management. Ulcers are persistent breaches in the skin or mucous membrane associated with cell death. Specific ulcer types discussed include traumatic, pressure, venous, arterial, diabetic, and malignant ulcers. Examination involves inspecting the ulcer size, edges, floor, and surrounding skin/tissue while also assessing for infection, vascular issues, and underlying causes. Management consists of treating any identified causes, controlling infection, debriding necrotic tissue, dressing the wound, and closing the defect once granulated.
Erysipelas is a bacterial skin infection that usually affects the top most layer of the skin. Erysipelas is very rare, but requires immediate treatment. Erysipelas is often associated with other skin infection known as cellulitis, which affects the lower layers of the skin.
This document discusses different conditions affecting the nails including paronychia, acute paronychia, chronic paronychia, and subungual hematoma. It describes the anatomy of the nail including the nail plate, matrix, lunula, cuticle, and nail bed. Acute paronychia is usually caused by minor nail injuries allowing bacterial infection, while chronic paronychia is often due to Candida infection. Treatment involves draining pus or blood and using antibiotics or antifungals. Subungual hematoma causes intense pain due to blood collecting under the nail requiring drainage through cautery or needle.
1) Osteomyelitis is a bone infection that can be acute or chronic. It is commonly caused by Staphylococcus aureus spreading via the bloodstream. Symptoms include bone pain and tenderness. Chronic osteomyelitis often affects the lower extremities and requires surgical debridement.
2) Septic arthritis is an infected joint, usually caused by S. aureus entering via the bloodstream. It presents as an inflamed large weight-bearing joint with fever. Joint fluid analysis and culture helps in diagnosis. Prompt antibiotics and drainage are needed to prevent joint damage.
3) Viral arthritis is caused by immune complexes depositing in joints after viral infections like rubella. Reactive
Felon or Terminal Pulp Infection is defined as an abscess of pulp of finger. It may involve the terminal , middle or proximal pulp space, sometimes distal pulp space.
Gas gangrene, also known as clostridial myonecrosis, is an infective gangrene caused by clostridial bacteria such as Clostridium perfringens. It commonly occurs after trauma with open wounds or crush injuries that are contaminated. The bacteria release toxins and enzymes that break down muscle tissue, producing gas in the affected areas. Symptoms include pain, fever, and foul-smelling discharge from wounds. Treatment involves aggressive surgical debridement of dead tissue combined with high-dose intravenous penicillin antibiotics. Hyperbaric oxygen therapy may also be used as an adjuvant treatment. Without prompt treatment, gas gangrene can lead to sepsis, organ failure, and death.
This document discusses felon, an abscess of the pulp space in the finger. It notes that felon most commonly involves the distal pulp space of the index or thumb finger, resulting from minor trauma such as a finger prick. The pulp space contains fat partitions and becomes a closed compartment, so minor infections can lead to pus collection and increased pressure, compressing the terminal artery and potentially causing gangrene. Treatment involves antibiotics, drainage of the terminal pulp space through a longitudinal incision, and possible amputation of the terminal phalanx if osteomyelitis is present.
This document discusses abscesses, including:
1. An abscess is a collection of pus surrounded by inflamed tissues and contains dead and dying white blood cells and bacteria.
2. Abscesses spread along paths of least resistance and increase pressure, causing pain. They eventually burst spontaneously or require incision and drainage.
3. Treatment involves rest, elevation, antibiotics, and incision and drainage surgery to fully open and curette the abscess cavity.
Dr. Shalu Gupta provides a detailed overview of ulcers, including their definition, anatomy, classification, causes, examination, and management. Ulcers are persistent breaches in the skin or mucous membrane associated with cell death. Specific ulcer types discussed include traumatic, pressure, venous, arterial, diabetic, and malignant ulcers. Examination involves inspecting the ulcer size, edges, floor, and surrounding skin/tissue while also assessing for infection, vascular issues, and underlying causes. Management consists of treating any identified causes, controlling infection, debriding necrotic tissue, dressing the wound, and closing the defect once granulated.
Erysipelas is a bacterial skin infection that usually affects the top most layer of the skin. Erysipelas is very rare, but requires immediate treatment. Erysipelas is often associated with other skin infection known as cellulitis, which affects the lower layers of the skin.
This document discusses different conditions affecting the nails including paronychia, acute paronychia, chronic paronychia, and subungual hematoma. It describes the anatomy of the nail including the nail plate, matrix, lunula, cuticle, and nail bed. Acute paronychia is usually caused by minor nail injuries allowing bacterial infection, while chronic paronychia is often due to Candida infection. Treatment involves draining pus or blood and using antibiotics or antifungals. Subungual hematoma causes intense pain due to blood collecting under the nail requiring drainage through cautery or needle.
1) Osteomyelitis is a bone infection that can be acute or chronic. It is commonly caused by Staphylococcus aureus spreading via the bloodstream. Symptoms include bone pain and tenderness. Chronic osteomyelitis often affects the lower extremities and requires surgical debridement.
2) Septic arthritis is an infected joint, usually caused by S. aureus entering via the bloodstream. It presents as an inflamed large weight-bearing joint with fever. Joint fluid analysis and culture helps in diagnosis. Prompt antibiotics and drainage are needed to prevent joint damage.
3) Viral arthritis is caused by immune complexes depositing in joints after viral infections like rubella. Reactive
Osteomyelitis is an infection of bone that can be caused by bacteria entering through the bloodstream or directly through a wound. It most commonly affects the long bones in children and the vertebrae in adults. Symptoms include fever, pain, swelling, and limited movement near the infected bone. Diagnosis involves blood tests, imaging like x-rays, CT, MRI, and bone scans to identify bone changes. Treatment consists of antibiotics given intravenously or orally for several weeks based on bacterial culture results, along with rest and pain medication.
Madura foot, also known as mycetoma, is a chronic granulomatous infection of the skin and subcutaneous tissues that enters through cuts or punctures and spreads along fascial planes. It is characterized by draining sinuses filled with hard nodules or grains. The disease is endemic in tropical regions and most commonly affects the foot. Diagnosis involves identifying the causative fungi or actinomycetes from grain samples. Treatment involves prolonged antifungal or antibiotic therapy, sometimes along with surgery. Complications can include secondary infection, deformity, and disability.
1. Osteomyelitis, septic arthritis, and tuberculosis are infectious diseases that can affect bones and joints. The document discusses the definition, incidence, bacteriology, predisposing factors, pathogenesis, clinical presentation, investigations, differential diagnosis, complications, and treatment of these conditions.
2. For osteomyelitis, the metaphysis of long bones is a common site of infection. Imaging such as x-rays, MRI, bone scans can identify bone changes. Treatment involves antibiotics, drainage of abscesses, and debridement of infected tissues.
3. Septic arthritis typically involves a single large joint. Presentation includes pain, swelling, fever. Joint fluid analysis and culture helps confirm the diagnosis
Osteomyelitis is an inflammation of bone caused by a bacterial infection. It can be acute, subacute, or chronic depending on symptom duration. Classification is also based on infection mechanism (exogenous or hematogenous) and host response (pyogenic or nonpyogenic). Common causes include Staphylococcus aureus and various bacteria depending on patient factors. Diagnosis involves identifying symptoms, obtaining cultures from lesions, and imaging tests like MRI. Treatment involves antibiotics as well as surgical drainage of pus and dead tissue.
Carbuncle is a skin infection caused by bacteria such as Staphylococcus and Streptococcus. It results in a painful, swollen lump under the skin that may contain pus and can develop in hairy areas. Carbuncles occur when hair follicles are infected by bacteria and involve a group of follicles. They are diagnosed through visual examination and sometimes tested fluid or blood samples. Treatment involves antibiotics, draining the carbuncle, and home remedies like warm compresses and cleaning with antibacterial soap.
Syphilis is caused by the bacterium Treponema pallidum and is transmitted sexually, from mother to fetus, or rarely by other means. It progresses through primary, secondary, latent, and late stages if left untreated. Primary syphilis presents as a chancre which can spread to nearby lymph nodes. Secondary syphilis causes a rash and mucous membrane lesions. Latent syphilis involves positive blood tests without symptoms. Late syphilis can damage internal organs like the heart, brain, and skin in the form of gummas. Syphilis screening and treatment are important to prevent transmission and complications. Congenital syphilis is transmitted from mother to fetus and can cause serious lifelong effects if
Ulcer is a break in the skin or mucous membrane. There are several types of ulcers including acute, chronic, spreading, and non-healing ulcers. Ulcers can be caused by infection, trauma, poor circulation, or underlying conditions like diabetes. The key parts of an ulcer include the margin, edge, floor, and base. Evaluation of an ulcer involves examining these parts and considering characteristics like appearance, drainage, surrounding skin, and tenderness. Investigation and management depends on the identified cause, with goals of cleaning the ulcer, promoting healing, treating underlying issues, and closing the wound.
Erysipelas is a bacterial skin infection caused by streptococci that extends into cutaneous lymphatics. It is characterized by a red, sharply demarcated, raised, and tender rash. The infection begins as a small erythematous patch that progresses and involves regional lymph nodes. Treatment involves antibiotics like penicillin for 10-20 days. Recurrence is common in patients with predisposing skin conditions. Complications can include abscesses, gangrene, and thrombophlebitis.
Varicose veins are swollen, enlarged veins that often appear blue or dark purple. They commonly occur in the legs but can affect other areas. Varicose veins are very common, affecting up to 30% of the UK adult population. While the exact cause is unknown, factors like family history, age, pregnancy, obesity, and standing for long periods can increase risk. Treatment options range from compression stockings and elevation for mild cases to invasive procedures like surgery or ablation techniques for more severe cases. The main risks of invasive treatments are nerve damage, which occurs in 8-40% of cases depending on the procedure and location of veins.
This document presents a case report of a 41-year-old female patient who presented with necrotizing fasciitis. She had a history of trauma to her lower right leg from being hit by a cow 10 days prior and subsequently developed pain, swelling, and fever in the leg. On examination, she had necrotic skin from below the knee to the top of the foot. Diagnostic workup showed elevated white blood cell count. She was diagnosed with septic shock secondary to necrotizing fasciitis and treated with aggressive debridement and antibiotics. Necrotizing fasciitis is a life-threatening soft tissue infection that rapidly destroys skin and tissue. It is usually caused by Group A strept
This document describes a case of necrotizing fasciitis in a 54-year-old man. The man presented with swelling and pain in his left lower leg, along with watery discharge and skin blisters. He had a history of an insect bite a month prior. Investigation revealed elevated white blood cell count and blood sugar. The patient was diagnosed with uncontrolled diabetes and necrotizing fasciitis. He underwent fasciotomy, debridement, and skin grafting. The wound culture grew Pseudomonas aeruginosa. With aggressive treatment including antibiotics, surgery, and control of his diabetes, the patient's condition improved.
Osteomyelitis is inflammation of bone and bone marrow that is usually caused by bacterial infection. Acute hematogenous osteomyelitis is the most common type seen in India, typically affecting the distal femur or proximal tibia in children. Staphylococcus aureus is the main causative organism. It presents with fever, pain, and swelling over the affected bone. Diagnosis is made through clinical features, lab tests showing elevated inflammatory markers, and imaging showing bone changes. Treatment involves antibiotics, surgical drainage of abscesses, and rest.
Acute and Chronic Osteomyelitis - Infection of BoneRahul Singh
Osteomyelitis is an inflammatory process of bone caused by bacterial infection. It can be acute, subacute, or chronic depending on duration and host response. Common causes are Staphylococcus aureus and trauma. Acute osteomyelitis presents with fever, pain, and swelling near the infected bone in children. Treatment involves antibiotics and surgical drainage. Chronic osteomyelitis results from inadequate treatment of acute infection and is characterized by persistent sinus tracts and bone destruction. Surgical debridement along with long-term antibiotics is usually required to treat chronic osteomyelitis.
Definition:
Madura foot or mycetoma (tumour-like)
Chronic granulomatous disease characterised by localised infection of subcutaneous tissues and sometimes bone characterised by discharging sinuses filled with organisms like actinomycetes or fungi.
History:
Gill first described the disease in the Madura district of India in 1842.
Hence the term Madura foot.
Pathophysiology:Typically present in agricultural workers(hands shoulders and back – from carrying contaminated vegetation and other burdens).
Causes:Due to fungi – eumycetoma (40%) or
Actinomycetes – (actinomycetoma) 60%
Actinomycetoma may be due to Actinomadura madurae Actinomadura pelletieri Streptomyces somaliensis Nocardia species
Clinical Features:Slow spreading skin infection
Local swelling
Small hard painless nodules
Ulceration
Pus discharge
Scarred skin & discoloration
Itching
Pain and burning sensation
Lab studies:Direct microscopy
Blood – leukocytosis & neutrophilia
Culture of exudates
Skin biopsy
Serology
DNA sequencing has been used for identification in difficult cases.
Microscopy:Serosanguinous fluid containing the granules examined using – 10% KOH and Parker ink or calcofluor white mounts
Tissue sections stained using H&E(Hematoxylin and Eosin stain) , PAS(Periodic Acid Shiffs Stain) and Grocott’s methenamine silver(GMS).
Actinomycotic grains contains very fine filaments.
Fungal grains contain short hyphae (branched filaments) that are often swollen
Culture:Sabouraud’s dextrose agar or mycobiotic agar to isolate fungi
Blood agar to isolate bacteria
Agar plates are cultured at 25-30 degree celcius and 37 degree celcius for up to six weeks . Fungi grow more quickly than actinomycetes.
Treatment;Due to the slow ,relatively pain –free progression of the disease, mycetoma is often at an advanced stage when diagnosed.
Antifungals
Antibiotics
Treatment of any secondary infections
Amputation-in severe cases
1. Osteomyelitis is a bone infection that can be primary (bloodborne) or secondary (following an open fracture or bone surgery).
2. The metaphysis of long bones is a common site for osteomyelitis due to its rich blood supply. Bacteria can become lodged in the hairpin loop vessels.
3. Early treatment involves antibiotics and immobilization. Late treatment may require surgery to drain pus from the bone. Complications can include chronic osteomyelitis, pathological fractures, or growth plate disturbances if not treated properly.
Diabetic foot is caused by the interaction of neuropathy, abnormal foot biomechanics, and peripheral arterial disease impairing wound healing. This leads to foot ulcers and infections, which are graded from 0 to 5 based on severity. Management involves glycemic control, footwear modification, wound care, and antibiotics or surgery depending on grade. Preventing and treating diabetic foot complications reduces lower extremity amputations.
This document discusses different types of abscesses and their treatment. There are three main types: pyogenic, pyaemic, and cold abscesses. Pyogenic abscesses result from bacterial infections and can develop from cellulitis or lymphadenitis. Treatment involves incision and drainage if pus is present. Pyaemic abscesses are caused by infectious emboli spreading through the bloodstream and result in multiple abscesses. Cold abscesses are typically tuberculous in nature and develop in lymph nodes or bones. Complete excision or drainage with antitubercular drugs is the treatment.
Venous ulcers account for nearly 80% of lower extremity ulcers and are caused by venous hypertension and reflux which damages the veins and capillaries. Risk factors include advancing age, family history, prolonged standing, obesity, smoking, and prior venous thrombosis. Conservative management involves compression therapy, elevation, exercise, and dressings. For severe or non-healing ulcers, surgical options like vein stripping or valvuloplasty may be used to correct venous reflux and lower pressure. Skin grafting can then promote wound closure.
Ganglion cysts are small, mucus-filled cysts that commonly occur on the back of the wrist. They can also develop on other joints like fingers, knees, and ankles. Ganglion cysts are usually painless bumps but can become painful with activity. Ultrasound or MRI can confirm the cystic nature of the bump. Treatment involves initial aspiration and steroid injection for small cysts. Larger or recurring cysts may require surgical excision to prevent reoccurrence.
parnoychia includes acute parnoychia & chronic panoychia. ACUTE PARONYCHIA
(paronychia means “Run around”).
It occurs in subcuticular area under the eponychium.
Minor injury to finger is the common cause.
chronic paronychia occurs due to bacterial supervention
Osteomyelitis is an infection of bone that can be caused by bacteria entering through the bloodstream or directly through a wound. It most commonly affects the long bones in children and the vertebrae in adults. Symptoms include fever, pain, swelling, and limited movement near the infected bone. Diagnosis involves blood tests, imaging like x-rays, CT, MRI, and bone scans to identify bone changes. Treatment consists of antibiotics given intravenously or orally for several weeks based on bacterial culture results, along with rest and pain medication.
Madura foot, also known as mycetoma, is a chronic granulomatous infection of the skin and subcutaneous tissues that enters through cuts or punctures and spreads along fascial planes. It is characterized by draining sinuses filled with hard nodules or grains. The disease is endemic in tropical regions and most commonly affects the foot. Diagnosis involves identifying the causative fungi or actinomycetes from grain samples. Treatment involves prolonged antifungal or antibiotic therapy, sometimes along with surgery. Complications can include secondary infection, deformity, and disability.
1. Osteomyelitis, septic arthritis, and tuberculosis are infectious diseases that can affect bones and joints. The document discusses the definition, incidence, bacteriology, predisposing factors, pathogenesis, clinical presentation, investigations, differential diagnosis, complications, and treatment of these conditions.
2. For osteomyelitis, the metaphysis of long bones is a common site of infection. Imaging such as x-rays, MRI, bone scans can identify bone changes. Treatment involves antibiotics, drainage of abscesses, and debridement of infected tissues.
3. Septic arthritis typically involves a single large joint. Presentation includes pain, swelling, fever. Joint fluid analysis and culture helps confirm the diagnosis
Osteomyelitis is an inflammation of bone caused by a bacterial infection. It can be acute, subacute, or chronic depending on symptom duration. Classification is also based on infection mechanism (exogenous or hematogenous) and host response (pyogenic or nonpyogenic). Common causes include Staphylococcus aureus and various bacteria depending on patient factors. Diagnosis involves identifying symptoms, obtaining cultures from lesions, and imaging tests like MRI. Treatment involves antibiotics as well as surgical drainage of pus and dead tissue.
Carbuncle is a skin infection caused by bacteria such as Staphylococcus and Streptococcus. It results in a painful, swollen lump under the skin that may contain pus and can develop in hairy areas. Carbuncles occur when hair follicles are infected by bacteria and involve a group of follicles. They are diagnosed through visual examination and sometimes tested fluid or blood samples. Treatment involves antibiotics, draining the carbuncle, and home remedies like warm compresses and cleaning with antibacterial soap.
Syphilis is caused by the bacterium Treponema pallidum and is transmitted sexually, from mother to fetus, or rarely by other means. It progresses through primary, secondary, latent, and late stages if left untreated. Primary syphilis presents as a chancre which can spread to nearby lymph nodes. Secondary syphilis causes a rash and mucous membrane lesions. Latent syphilis involves positive blood tests without symptoms. Late syphilis can damage internal organs like the heart, brain, and skin in the form of gummas. Syphilis screening and treatment are important to prevent transmission and complications. Congenital syphilis is transmitted from mother to fetus and can cause serious lifelong effects if
Ulcer is a break in the skin or mucous membrane. There are several types of ulcers including acute, chronic, spreading, and non-healing ulcers. Ulcers can be caused by infection, trauma, poor circulation, or underlying conditions like diabetes. The key parts of an ulcer include the margin, edge, floor, and base. Evaluation of an ulcer involves examining these parts and considering characteristics like appearance, drainage, surrounding skin, and tenderness. Investigation and management depends on the identified cause, with goals of cleaning the ulcer, promoting healing, treating underlying issues, and closing the wound.
Erysipelas is a bacterial skin infection caused by streptococci that extends into cutaneous lymphatics. It is characterized by a red, sharply demarcated, raised, and tender rash. The infection begins as a small erythematous patch that progresses and involves regional lymph nodes. Treatment involves antibiotics like penicillin for 10-20 days. Recurrence is common in patients with predisposing skin conditions. Complications can include abscesses, gangrene, and thrombophlebitis.
Varicose veins are swollen, enlarged veins that often appear blue or dark purple. They commonly occur in the legs but can affect other areas. Varicose veins are very common, affecting up to 30% of the UK adult population. While the exact cause is unknown, factors like family history, age, pregnancy, obesity, and standing for long periods can increase risk. Treatment options range from compression stockings and elevation for mild cases to invasive procedures like surgery or ablation techniques for more severe cases. The main risks of invasive treatments are nerve damage, which occurs in 8-40% of cases depending on the procedure and location of veins.
This document presents a case report of a 41-year-old female patient who presented with necrotizing fasciitis. She had a history of trauma to her lower right leg from being hit by a cow 10 days prior and subsequently developed pain, swelling, and fever in the leg. On examination, she had necrotic skin from below the knee to the top of the foot. Diagnostic workup showed elevated white blood cell count. She was diagnosed with septic shock secondary to necrotizing fasciitis and treated with aggressive debridement and antibiotics. Necrotizing fasciitis is a life-threatening soft tissue infection that rapidly destroys skin and tissue. It is usually caused by Group A strept
This document describes a case of necrotizing fasciitis in a 54-year-old man. The man presented with swelling and pain in his left lower leg, along with watery discharge and skin blisters. He had a history of an insect bite a month prior. Investigation revealed elevated white blood cell count and blood sugar. The patient was diagnosed with uncontrolled diabetes and necrotizing fasciitis. He underwent fasciotomy, debridement, and skin grafting. The wound culture grew Pseudomonas aeruginosa. With aggressive treatment including antibiotics, surgery, and control of his diabetes, the patient's condition improved.
Osteomyelitis is inflammation of bone and bone marrow that is usually caused by bacterial infection. Acute hematogenous osteomyelitis is the most common type seen in India, typically affecting the distal femur or proximal tibia in children. Staphylococcus aureus is the main causative organism. It presents with fever, pain, and swelling over the affected bone. Diagnosis is made through clinical features, lab tests showing elevated inflammatory markers, and imaging showing bone changes. Treatment involves antibiotics, surgical drainage of abscesses, and rest.
Acute and Chronic Osteomyelitis - Infection of BoneRahul Singh
Osteomyelitis is an inflammatory process of bone caused by bacterial infection. It can be acute, subacute, or chronic depending on duration and host response. Common causes are Staphylococcus aureus and trauma. Acute osteomyelitis presents with fever, pain, and swelling near the infected bone in children. Treatment involves antibiotics and surgical drainage. Chronic osteomyelitis results from inadequate treatment of acute infection and is characterized by persistent sinus tracts and bone destruction. Surgical debridement along with long-term antibiotics is usually required to treat chronic osteomyelitis.
Definition:
Madura foot or mycetoma (tumour-like)
Chronic granulomatous disease characterised by localised infection of subcutaneous tissues and sometimes bone characterised by discharging sinuses filled with organisms like actinomycetes or fungi.
History:
Gill first described the disease in the Madura district of India in 1842.
Hence the term Madura foot.
Pathophysiology:Typically present in agricultural workers(hands shoulders and back – from carrying contaminated vegetation and other burdens).
Causes:Due to fungi – eumycetoma (40%) or
Actinomycetes – (actinomycetoma) 60%
Actinomycetoma may be due to Actinomadura madurae Actinomadura pelletieri Streptomyces somaliensis Nocardia species
Clinical Features:Slow spreading skin infection
Local swelling
Small hard painless nodules
Ulceration
Pus discharge
Scarred skin & discoloration
Itching
Pain and burning sensation
Lab studies:Direct microscopy
Blood – leukocytosis & neutrophilia
Culture of exudates
Skin biopsy
Serology
DNA sequencing has been used for identification in difficult cases.
Microscopy:Serosanguinous fluid containing the granules examined using – 10% KOH and Parker ink or calcofluor white mounts
Tissue sections stained using H&E(Hematoxylin and Eosin stain) , PAS(Periodic Acid Shiffs Stain) and Grocott’s methenamine silver(GMS).
Actinomycotic grains contains very fine filaments.
Fungal grains contain short hyphae (branched filaments) that are often swollen
Culture:Sabouraud’s dextrose agar or mycobiotic agar to isolate fungi
Blood agar to isolate bacteria
Agar plates are cultured at 25-30 degree celcius and 37 degree celcius for up to six weeks . Fungi grow more quickly than actinomycetes.
Treatment;Due to the slow ,relatively pain –free progression of the disease, mycetoma is often at an advanced stage when diagnosed.
Antifungals
Antibiotics
Treatment of any secondary infections
Amputation-in severe cases
1. Osteomyelitis is a bone infection that can be primary (bloodborne) or secondary (following an open fracture or bone surgery).
2. The metaphysis of long bones is a common site for osteomyelitis due to its rich blood supply. Bacteria can become lodged in the hairpin loop vessels.
3. Early treatment involves antibiotics and immobilization. Late treatment may require surgery to drain pus from the bone. Complications can include chronic osteomyelitis, pathological fractures, or growth plate disturbances if not treated properly.
Diabetic foot is caused by the interaction of neuropathy, abnormal foot biomechanics, and peripheral arterial disease impairing wound healing. This leads to foot ulcers and infections, which are graded from 0 to 5 based on severity. Management involves glycemic control, footwear modification, wound care, and antibiotics or surgery depending on grade. Preventing and treating diabetic foot complications reduces lower extremity amputations.
This document discusses different types of abscesses and their treatment. There are three main types: pyogenic, pyaemic, and cold abscesses. Pyogenic abscesses result from bacterial infections and can develop from cellulitis or lymphadenitis. Treatment involves incision and drainage if pus is present. Pyaemic abscesses are caused by infectious emboli spreading through the bloodstream and result in multiple abscesses. Cold abscesses are typically tuberculous in nature and develop in lymph nodes or bones. Complete excision or drainage with antitubercular drugs is the treatment.
Venous ulcers account for nearly 80% of lower extremity ulcers and are caused by venous hypertension and reflux which damages the veins and capillaries. Risk factors include advancing age, family history, prolonged standing, obesity, smoking, and prior venous thrombosis. Conservative management involves compression therapy, elevation, exercise, and dressings. For severe or non-healing ulcers, surgical options like vein stripping or valvuloplasty may be used to correct venous reflux and lower pressure. Skin grafting can then promote wound closure.
Ganglion cysts are small, mucus-filled cysts that commonly occur on the back of the wrist. They can also develop on other joints like fingers, knees, and ankles. Ganglion cysts are usually painless bumps but can become painful with activity. Ultrasound or MRI can confirm the cystic nature of the bump. Treatment involves initial aspiration and steroid injection for small cysts. Larger or recurring cysts may require surgical excision to prevent reoccurrence.
parnoychia includes acute parnoychia & chronic panoychia. ACUTE PARONYCHIA
(paronychia means “Run around”).
It occurs in subcuticular area under the eponychium.
Minor injury to finger is the common cause.
chronic paronychia occurs due to bacterial supervention
A PPT on neurocutaneous markers containing
short history, and short description of following N C markers
Cafe au lait spots
Ash leaf patch
Litsch nodules
Axillary and inguinal freckling.
Facial angiofibromas .
Cutaneous neurofibromatosis.
Multiple unqualified fibromas .
Cutaneous neurofibromatosis
Adenoma sebacum.
Hypo / hyper pigmented Macules
hairy tuft at sacrum.
Facial angioma /Port wine stain
The document discusses diseases and abnormalities of the nails. It covers:
1. The anatomy and growth of normal nails.
2. Common nail disorders including trauma, fungal infections, psoriasis, and nail changes associated with systemic diseases.
3. Nail tumors such as warts and melanomas that can appear under the nail.
4. Rare inherited nail disorders with characteristic thickened or malformed nails.
Selected human infectious diseases part 2Jason Sulit
This document describes staphylococcal scalded skin syndrome (SSSS) and toxic epidermal necrolysis (TEN) in neonates and children. It includes photos showing large areas of skin denudation and blistering. SSSS is caused by a toxin that separates the epidermis from the dermis. The affected areas dry out and flake off over 2 weeks. It is treated with intravenous penicillin and fluid replacement. TEN has a similar appearance but is usually drug-induced or due to infection. High-dose steroids may be used to treat TEN. Biopsy is important to differentiate the two conditions.
The document discusses various diseases and conditions that can affect the external nose and nasal vestibule. It describes cellulitis, nasal deformities like saddle nose and hump nose, and various types of tumors including dermoid cysts, encephaloceles, and basal cell carcinoma. It also discusses injuries to the nose including nasal fractures and injuries to the paranasal sinuses. Other conditions mentioned include furuncles, vestibulitis, stenosis of the nares, and epistaxis (nosebleeds). The treatments involve antibiotics, steroids, surgery, and procedures to repair nasal fractures and deformities.
This document provides information on white lesions of the oral cavity, including definitions, classifications, and management. It discusses hereditary conditions like leukoedema and white sponge nevus. It also covers reactive lesions such as frictional keratosis and nicotine stomatitis. Immunological conditions like lichen planus and infectious causes including candidiasis and oral hairy leukoplakia are described. Potentially malignant disorders such as leukoplakia are also outlined. The document provides details on clinical presentation and treatment of these various white oral lesions.
This document discusses various diseases and abnormalities of the external nose and nasal cavity. It covers topics such as nasal furunculosis, nasal vestibulitis, saddle nose, hump nose, crooked nose, congenital tumors like dermoid cyst and encephalocele, nasolabial cyst, rhinophyma, papilloma, basal cell carcinoma, squamous cell carcinoma, melanoma, hemangioma, foreign bodies, and rhinolithiasis. Treatment approaches including antibiotics, anti-inflammatory drugs, rhinoplasty, reconstruction, and surgery are described for many of these conditions.
The document discusses various hand infections including paronychia, felon, pyogenic flexor tenosynovitis, and deep space infections. Paronychia typically involves the nail fold and is usually caused by Staphylococcus aureus, while a felon is a deep pulp space abscess of the finger that requires surgical drainage. Pyogenic flexor tenosynovitis is a surgical emergency that infects the closed flexor tendon sheath and can lead to tendon necrosis if not promptly drained.
Treponema pallidum is a spirochete bacterium that causes the sexually transmitted disease syphilis. It has four stages: primary, secondary, latent, and tertiary. Primary syphilis presents as a chancre, while secondary syphilis causes a rash and mucous membranes lesions. Without treatment, later stages can involve the cardiovascular system, central nervous system, and other organ systems. Syphilis screening and treatment are important for preventing transmission and progression of disease.
This document provides an overview of osteomyelitis, beginning with definitions, predisposing factors, etiology, pathogenesis, classification and staging, clinical features, investigation, and treatment. It discusses several types of osteomyelitis in more detail, including infantile osteomyelitis, Garre's sclerosing osteomyelitis, chronic sclerosing osteomyelitis, actinomycotic osteomyelitis of the jaws, and osteoradionecrosis. The document contains detailed information on the microbiology, pathogenesis, clinical presentation, imaging findings, and management approaches for osteomyelitis.
This document provides information about three skin conditions: pityriasis rosea, psoriasis, and lichen planus. It defines each condition and discusses their causes, types, clinical features, differential diagnosis, investigations, and treatment options. Pityriasis rosea causes an acute rash mainly affecting young adults. Psoriasis is a chronic inflammatory skin condition affecting the scalp, elbows, knees and other areas. Lichen planus causes irritation and swelling of the skin, hair, nails and mucous membranes in various forms. The document provides details on diagnosing and managing each condition.
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This document discusses the structure and functions of skin. It provides details on the layers of the epidermis and dermis. Various skin appendages like hair follicles and sebaceous glands are also mentioned. The document then discusses several common dermatological conditions like psoriasis, lichen planus, bacterial and fungal infections, blistering disorders, and tumors of the skin. Macroscopic and microscopic features of these conditions are described along with their pathogenesis and clinical presentation. Common benign tumors of the skin like seborrheic keratosis and premalignant lesions like actinic keratosis are also summarized.
Cruisier gUNS update coz why not. this isharshal1994
This document provides information on various weapon types in an online game, including their time to kill, DPS (damage per second), and unload damage. It shows that Dual Impact has the shortest time to kill at 2:57:72 and highest DPS at 152,000, while Dual Mauler has the longest time to kill at 3:12:79 and lowest DPS at 66,110. Several other weapon combinations are also listed along with their stats. The bottom section provides medical definitions and descriptions of oral lesions, cysts, tumors and other conditions.
This document provides information on subcutaneous mycoses (mycoses of implantation), which are fungal infections caused by direct inoculation of fungi into the skin or subcutaneous tissue through a penetrating injury. It discusses several specific subcutaneous mycoses in detail, including mycetoma (Madura foot), sporotrichosis, lobomycosis, rhinosporidiosis, and chromoblastomycosis. For each, it covers topics such as causative organisms, epidemiology, clinical features, diagnosis, treatment and histopathological findings.
The document discusses infections of the hand, covering anatomy, classifications, causes, symptoms, and treatments. It describes various types of infections including spreading infections, localized infections in specific areas like the dorsum or palmar surface, paronychium (nail fold infection), apical subungual infection, terminal pulp space (felon) infection, web space infection, deep palmar abscess, and acute suppurative tenosynovitis. Common symptoms are pain, swelling, erythema and tenderness, while treatments involve antibiotics, surgical drainage of abscesses, and debridement as needed. Complications can include extension of infection, chronic infections, and stiffness.
Similar to Hand infection by Dr.K.AmrithaAnilkumar (20)
STRICTURE URETHRA
CLASSIICATION -I
I: Aetiologically.
2. Congenital.
3. Inflammatory:
Post-gonococcal
is most common
Gonococcal stricture occurs one year after infection.
Retention develops only 10–15 years later.
Rupture of the anterior urethra is usually caused by a fall astride a projecting object. Clinical features include blood in the urethra, a perineal hematoma, and retention of urine. Treatment involves gentle catheterization in the operating room. If catheterization is not possible, open surgical repair of the tear is performed through a perineal incision. Complications can include infection and stricture formation.
RENAL CALCULUS AETIOLOGY
Males- radio-opaque gall stones
Females - Radiolucent gall stones
Diet:Vitamin A deficiency
it causes desquamation of epithelium
which acts as a nidus for stone formation.
Climate:
In hot climate urinary solutes will increase with decrease in colloids,
PARAPHIMOSIS
DEFINITION
Inability to place back (cover) the retracted prepucial skin over the glans is called as paraphimosis.
It causes ring like constriction proximal to the corona and prepuceal skin.
HYPOSPADIAS
DEFINITION
It is the most common congenital malformation of urethra wherein external meatus is situated proximal than normal, over the ventral (under) aspect of the penis.
HYDRONEPHROSIS (HN)
DEFINITION
It is an aseptic dilatation of pelvicalyceal system due to partial or intermittent obstruction to the outflow of urine.
AETIOLOGY
unilateral
bilateral.
EPISPADIAS
Here the urethra opens on the dorsum of the penis, proximal to the glans.
COMMON SITES
abdominopenile junction.
It is associated with a dorsal chordee, ectopia vesicae, urinary incontinence, separated pubic bones.
It is uncommon in females.
This document discusses benign prostate hyperplasia (BPH), including its etiology, pathology, clinical features, diagnosis, and treatment. BPH is a non-cancerous enlargement of the prostate that occurs in older men due to an imbalance of hormones. It causes obstruction of the urethra and symptoms like frequent urination, weak urine stream, and retention. Diagnosis involves exams, urine and blood tests, and imaging of the prostate, kidneys, and bladder. Treatment depends on symptoms and complications but may include catheterization, surgery to remove part of the prostate like TURP, or other procedures to relieve blockage.
Varicocele is dilatation and tortuosity of the veins within the scrotum that drain blood from the testicles. It is more common on the left side where the left testicular vein drains directly into the left renal vein. Varicocele can cause increased temperature in the scrotum and impair sperm production. Treatment involves surgical ligation of the affected veins to repair blood flow and potentially improve fertility.
TESTICULAR TUMOURS
PREVALANCE
99% of testicular tumours are malignant.
Life time prevalence of getting testicular tumour is 0.2%.
Very common in Scandinavia; least common inAfrica andAsia.
4 times common in whites than blacks.
ORCHITIS
AETIOLOGY
It is an inflammation of the testis.
It is commonly associated with inflammation ofthe epididymis. Hence, called as epididymo-orchitis.
Orchitis is due to infection through blood, lymphatics or epididymis.
EPIDIDYMITIS,
CAUSES
Inflammation of epididymis is commonly associated with orchitis— epididymo-orchitis.
Nonspecific
viral like mumps.
Bacterial.
Filarial.
Tuberculosis
PERFORATED PEPTIC ULCER
PERFORATION
DEFINITION
It is the terminology used for perforation of duodenal ulcer or gastric ulcer or stomal ulcer.
Otherwise all clinical features and management are similar.
Perforation is common in duodenal ulcer
Mortality is more in gastric ulcer perforation and perforation in elderly
GASTRIC ULCER
AETIOLOGY
It occurs due to imbalance between protective and damaging factors of gastric mucosa.
Atrophic gastritis
duodenogastric bile reflux
gastric stasis
abnormalities in acid and pepsin secretion.
Acid becomes ulcerogenic even to normal gastric mucosa.
CURLING ULCER
DEFINITION
They are acute ulcers which develop after major burns, presenting as pain in epigastric region, vomiting or haematemesis.
Curling’s ulcer occurs when burn injury is more than 35%.
It is observed in the body and fundus not in antrum and duodenum
Congenital (infantile) hypertrophic pyloric stenosis by Dr.K.AmrithaAnilkumarDr. Amritha Anilkumar
CONGENITAL (INFANTILE) HYPERTROPHIC PYLORIC STENOSIS
DEFINITION
It is hypertrophy of musculature of pyloric antrum, especially the circular muscle fibres, causing primary failure of pylorus to relax.
Duodenum is normal.
CARCINOMA STOMACH
INCIDENCE
‘It is the captain of men of death’.
It is more common in Japan—70 per 1,00,000 population.
It is more common in males 2:1.
Decrease incidence in western world
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
Nutritional deficiency Disorder are problems in india.
It is very important to learn about Indian child's nutritional parameters as well the Disease related to alteration in their Nutrition.
Know the difference between Endodontics and Orthodontics.Gokuldas Hospital
Your smile is beautiful.
Let’s be honest. Maintaining that beautiful smile is not an easy task. It is more than brushing and flossing. Sometimes, you might encounter dental issues that need special dental care. These issues can range anywhere from misalignment of the jaw to pain in the root of teeth.
Debunking Nutrition Myths: Separating Fact from Fiction"AlexandraDiaz101
In a world overflowing with diet trends and conflicting nutrition advice, it’s easy to get lost in misinformation. This article cuts through the noise to debunk common nutrition myths that may be sabotaging your health goals. From the truth about carbohydrates and fats to the real effects of sugar and artificial sweeteners, we break down what science actually says. Equip yourself with knowledge to make informed decisions about your diet, and learn how to navigate the complexities of modern nutrition with confidence. Say goodbye to food confusion and hello to a healthier you!
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
Discover the benefits of homeopathic medicine for irregular periods with our guide on 5 common remedies. Learn how these natural treatments can help regulate menstrual cycles and improve overall menstrual health.
Visit Us: https://drdeepikashomeopathy.com/service/irregular-periods-treatment/
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)MuskanShingari
Statistics- Statistics is the science of collecting, organizing, presenting, analyzing and interpreting numerical data to assist in making more effective decisions.
A statistics is a measure which is used to estimate the population parameter
Parameters-It is used to describe the properties of an entire population.
Examples-Measures of central tendency Dispersion, Variance, Standard Deviation (SD), Absolute Error, Mean Absolute Error (MAE), Eigen Value
3. HANDINFECTION
Definition
• Hand contains
neurovascular bundles,
muscles, bones and
ligaments.
• Infectionmay be due to
minor injuries or blood
borne.
PRICIPITINGCAUSES
• Diabetes
• Immunosuppression
• HIV infection
• Vascular diseases
COMMONORGANISMS
• Staphylococcus aureus-
most common – 90%
• Gram-negative organisms
like
• E. coli
• Klebsiella
• Pseudomonas
4. PATHOLOGY
Infectionspreads faster
↓
Causes oedema due to lax skin
↓
looks like frog hand
↓
Restricted movements of
fingers and hand.
↓
The handfunctions like hook,
pinch, grip, graspare lost.
SYMPTOMS
• Severe pain
• Tenderness withfever.
• Tender palpable
axillary lymphnodes
are oftenpresent
5. TYPESOF HANDINFECTION
1. Acute paronychia.
2. Chronicparonychia.
3. Terminal pulp space
infection(felon).
4. Subungualinfection.
5. Web space infection.
6. Mid-palmar space
infection.
7. Thenarspace infection.
8. Deep palmar abscess.
9. Acutesuppurative
10. tenosynovitis.
11. Chronictenosynovitis
12. Lymphangitis of the
hand.
13. Arthritis of hand joints.
14. Subcuticular abscess
6. INVESTIGATIONS
• Pus culture
• Blood sugar.
• Urine sugar and ketone
bodies.
• Arterial Doppler of the
handif needed.
TREAMENT
• Antibiotictherapy.
• Positionof rest with wrist
slightly abductedand
extended, thumb and
index fingers away (glass-
holding position).
REFERENCE
1. SRB's Manual of Surgery
by SriramBhat M
2. A Manual on Clinical
Surgeryby Das
3. A Concise textbookof
Surgeryby Das
Glass holding position
10. • Suppuration occurs very
rapidly.
• It tracks aroundthe skin
marginand spreads under
the nail causing hang nail
or floating nail.
CAUSATIVEORGANISM
• Staphylococcus aureus
• Streptococcus pyogenes.
11. CLINICALFEATURES
• Severe throbbing pain
• tenderness(dependent
throbbing)
• visible pus under the nail
root.
• Nail on touchis very tender
(paronychiameans “Run
around”).
12. TREATMENT
• Pus is sent for culture and
sensitivity.
• Antibiotics like cloxacillin,
amoxicillin.
• Pus is drained by making an
incisionover the eponychium
• Digital blockusing
xylocaine 2%plain
(withoutadrenaline as end
arterysupply to digits can
develop arterospasm) is
givenas anaesthesia
13. • If there is a floating nail,
thenthe nail is dead & it has
to be removed
• Recoveryis fast
14. CHRONIC
PARONYCHIA
FEATURES
• It is common in
females.
• Nail is diseased with
ridges and
pigmentation.
• Itching in the nail bed.
• Recurrent pain,
discharge
• Secondary bacterial
infectionmay
supervene
20. TERMINALPULP INFECTION
FELON
• Felon is an abscessof pulp of
the finger
• It may involve the terminal,
middle or proximal pulp
space , sometimes distal pulp
space
• It is the secondmost
commonhand infection
(25%).
• Indexand thumb are
commonly affected.
• Usually by a minor injury
likefinger prick.
21. ORGANISMS
• Staphylococcus—most
common.
• Streptococcus, Gram-
negative organisms.
CLINICALFEATURES
• Pain, tenderness,
swelling in the
terminal phalanx.
• Fever.
• Tender axillarylymph
nodes.
• Oftensuppuration is
severe, forming collar
studabscesswhich
eventually may burst.
Staphylococus
Streptococus
22. INVESTIGATION
• X-rayof the part is
required oftento rule
out osteomyelitis of
terminal phalanx.
• Pus for culture and
sensitivity.
COMPLICATION
• Osteomyelitis of the
terminal phalanx.
• Pyogenicarthritis of
distal interphalangeal
jointand tenosynovitis
of flexor sheath.
• Septicaemia—in
immunosuppressed
individuals
23. TREATMENT
• Antibiotics and
analgesics.
• Drainage of terminal
pulp space by an
oblique deepincision.
• If there is osteomyelitis
of the terminal
phalanx, it has to be
amputated.
24. REFERENCE
1. SRB's Manual of Surgery
by SriramBhat M
2. A Manual on Clinical
Surgeryby Das
3. A Concise textbookof
Surgeryby Das
27. CORN
DEFINITION
• A Corn is thickenedskin on
thetop or side of a toe.
• They formto protect the skin
• They are two types
• The typeis determined by
theinner core , which canbe
soft or hard
TYPES
• Hardcorn.
• Soft corn.
28. Soft
• It usually occurs between
4thand 5th toes due to
friction of bases of
adjacentproximal
phalanges.
HARD
• It is localisedarea of
thickening over a bony
projec tions likeheads of
metatarsals.
• Histologicallyit differs from
callosityby having severe
keratoses witha central core
of degeneratedcells and
cholesterol.
• It presses over the adjacent
nerves causing pain.
29. • It can get infectedcausing
severe painand tender ness
with inability to walk.
• It is smaller lesion whichis
pusheddeepinto the skin
• Forming a localisedpalpable
painful/tender nodule with a
central yellow- white core of
deadcornifiedskin.
30. CLINICALFEATURES
• Corn is common if thereis
deformity or by wearing
tight fitting shoes/foot
wears.
• Corn is narrow, deep and
painful/tender.
• It is common in females.
• Corn is usually
white/gray/yellowcoloured,
deep seatedlesion
• Infection, abscess
formation and ulceration
can occur especially if
patient is diabetic.
• Cornmay be associated
with bursae causing
bursitis.
• Corn often recurs after
excision.
31. TREATMENT
• Excision.
• Local application of salicylic
acidpreparations or mixture
of salicylicacid/lactic
acid/collodionmay be
helpful.
• Skin softening agents are
also tried.
• Eliminating the pressure is
very important to prevent
recurrence.
Excisio
n
32. • Avoid excision of corn
unnecessarily in diabetic
(especiallywithneuropathy)
and in ischaemic foot.
REFERENCE
1. SRB's Manual of Surgery
by SriramBhat M
2. A Manual on Clinical
Surgeryby Das
3. A Concise textbookof
Surgeryby Das
Avoid excision –
Diabetic &
ischaemic foot
35. INFECTIONOF WEB SPACE
CAUSES
• Abrasion.
• Infectionof proximal volar
space of finger.
• Callosities.
• Infectionof proximal
spaces.
• Trauma.
• Spread fromother palmar
spaces and fromflexor
sheaths throughlumbrical
canal.
Web space infections
36. CAUSATIVEORGANISM
• Staphylococcus.
• Streptococcus.
• Gram-negative
organisms.
CLINICALFEATURES
• Fever.
• Painand tenderness.
• Oedemaof dorsumof
hand.
• Maximumtendernessis
on the volar aspect.
• ‘V’ sign—separationof
fingers.
• If untreated, infection
may spreadinto other web
spaces and hand spaces.
37. TREATMENT
• Elevationof hand.
• Antibiotics and analgesics.
• Drainage under regional or
general anaesthesia.
• A horizontal incisionis
placed on volarskin of the
web and deepened to reach
thespace by dividing fibres
of palmar fascia.
• Pus is drained and sent for
culture and sensitivity.
38. • If other web spaces are
involved theyshouldbe
drained througha separate
incision.
• Edges of the wound are cut
to leave a diamondshaped
opening in front.
• Oftencounter-incision over
dorsal skin of web is
needed.
.
39. • Antibiotics and analgesics.
• Drainage of terminal pulp
space by an oblique deep
incision.
• If there is osteomyelitis of
the terminal phalanx, it has
to be amputated.
COMPLICATION
• Osteomyelitis of the
terminal phalanx.
• Pyogenicarthritis of distal
interphalangeal joint and
tenosynovitis of flexor
sheath.
• Septicaemia—in
immunosuppressed
individuals
40. en love da Homoeopathy
INGROWING TOE NAIL/
GROWING TOE NAIL
(Onychocryptosis)
42. INGROWINGTOE NAIL/
ONYCHOCRYPTOSIS/
GROWINGTOE NAIL
(Onychocryptosis)
• It is also calledas embedded
toe nail.
• It is due to curling of the
side of nail inwards, causing
it to forma lateral spike
• resulting in repeated
irritationand infection of
overhanging tissues in the
nail fold.
CAUSES
• Tight shoes.
• Improper cutting of nails
(veryshort and convex).
43. CLINICALFEATURES
• It is commonin great toe
and is often bilateral.
• Bothmedial and lateral
sides of the toe can be
involved.
• Recurrent attacks of acute
and subacute paronychia
occurs.
• Pain
• Tenderness
• swelling of margins of the
toe
• oftenalong with
granulation tissue
• foul smelling discharge
44. TREATMENT
• Regular dressing and
packing.
• Antibiotics.
• Discharge is sent for culture
and sensitivity.
• Zadik’s or Fowler’s operation
• Nails should be cut concavely
or straight withoutleaving
lateral spikes towards soft
tissues. Zadik’s /
Fowler’s operation
45. • Antibiotics and analgesics.
• Drainage of terminal pulp
space by an oblique deep
incision.
• If there is osteomyelitis of
the terminal phalanx, it has
to be amputated.
46. COMPLICATION
• Osteomyelitis of the
terminal phalanx.
• Pyogenicarthritis of
distal
interphalangeal joint
and tenosynovitis of
flexor sheath.
• Septicaemia—in
immunosuppressed
individuals
Pyogenic arthritis
osteomyelitis
septicemia
47. en love da Homoeopathy
PALMAR SPACE
INFECTION/
MID PALMAR
INFECTION
49. PALMAR SPACE INFECTION
MIDPALMAR INFECTION
CAUSES
• Trauma.
• Spread frominfection
of finger spaces and web
spaces.
• Haematogenous
spread.
• Spreadfrom
tenosynovitis
50. CLINICALFEATURES
• Painand tendernessin
the palm.
• Oedema of dorsumof
hand(frog hand).
• Loss of concavity of
palm.
• Painful movement of
metacarpophalangeal
joint(but
interphalangeal joint
movements are normal
and pain-free).
51. TREATMENT
• Elevationof the affected
limb.
• Antibiotics and analgesics.
• Drainthe pus
• Fever.
• Palpabletender axillary
lymph nodes.
• Eventually pus may come
out of palmar
aponeurosis forming
collar studabscess
• & later sinus formation.
Drain the pus by incision
52. REFERENCE
1. SRB's Manual of Surgery
by SriramBhat M
2. A Manual on Clinical
Surgery by Das
3. A Concise textbookof
Surgery by Das
COMPLICATION
• Osteomyelitis of
metacarpals
• Stiffnessof hand
• Suppurative arthritis
• Extensionof infection
into other spaces.
Osteomyelitis of metacarpals
53. en love da Homoeopathy
PARANO INFECTION/
ACUTE SUPPURATIVE
TENOSYNOVITIS
56. CLINICALFEATURES
• Symmetrical swelling of
entire finger.
• Flexionof finger—Hook
sign.
• Severe pain on extension.
• Tendernessover the
sheath.
• Oedema of whole hand,
bothpalm and dorsum
(due to lymphaticspread).
• As ulnarbursa extends into
the little finger ,
• its infectionresults in pain
and tenderness extending up
to little finger but not much
to other fingers
57. • Kanavel signs
• Swollenfinger held in
flexion
• Exquisite pain on
passive extension
• Tenderness precisely
over the tendonsheath
• Area of greatest
tendernessoverthe
part of ulnar bursa
lying between
transversepalmar
creases.
59. • In infection of radial bursa
• thumb is swollenwith
painand tenderness
over the sheathof the
flexor pollicis longus
• &there is
inextensibilityof
interphalangeal joint.
• Swelling just above
the flexor retinaculum
is common.
60. TREATMENT
• Elevationof the affected
limb.
• Antibiotics and analgesics.
• Positionof rest.
• Drainageunder general
anaesthesia.
• Incisions are placed over the
site of maximumtenderness
and flexor sheathshouldbe
openedup.
• Many a times multiple
incisions are required.
61. COMPLICATION
• Spreadof infection
proximallyinto forearm-
to space of Parona
• Stiffnessof fingers and
hand
• Suppurative arthritis
• Osteomyelitis
• Mediannerve palsy
• Bacteraemia
• septicaemia
Suppurative arthritis
Median nerve palsy
62. en love da Homoeopathy
DUPUYTREN’S
CONTRACTURE
64. DUPUYTREN’S
CONTRACTURE
DEFINITION
• It refers to localised
thickening of palmar
aponeurosis and later
formation of nodules with
severe permanent changes
in metacarpophalangeal and
proximal interphalangeal
joints.
• It is common in males
• Terminal interphalangeal
jointis not involvedas
palmar aponeurosis does
not extend to terminal
phalanx.
DUPUYTREN’S
CONTRACTURE
65. COMMONSITE
• It starts in ringand little
fingers, withflexionof
ring and little fingers.
• Laterinvolving all fingers.
• There is thickening and
nodule formation in the
palmwith adherent skin.
• It is oftenfamilial and
bilateral 45%.
• Pads(of fat) develop in
knuckles and are called as
Garrod’s pads (in
proximal IP joints)
Garrod’s pads
66. AETIOLOGY
• Repeatedminor trauma,
use of vibrating tools.
• Cirrhosis
• Alcoholism
• smoking,
• Epileptics on treatment
with phenytoin sodium.
• Diabetics
• pulmonary tuberculosis,
• AIDS.
• Other metabolic
conditions.
• Familial—autosomal
dominant
68. • TRIAD- Galezia triad
• Dupuytren’s contracture
• Retroperitoneal fibrosis
• Peyronie’s diseaseof
penis.
Dupuytren’s
contracture
Retro
peritonealfibrosis
Peyronie’sdiseaseof
penis.
COMPLICATION
• Restriction of handfunction
and so disability.
• Arthritis of MCP &
proximal IP joints.
• Fasciotomy of palmar
aponeurosis and later physio
therapy, Z plasty.
• In severe cases fasciotomy
partial or complete.
69. TREATMENT
• Treat the cause.
RECURRENCE
• Recurrence can occur
in 5–50%cases.
REFERENCE
1. SRB's Manual of Surgery
by SriramBhat M
2. A Manual on Clinical
Surgeryby Das
3. A Concise textbookof
Surgeryby Das
70. en love da Homoeopathy
VOLKMANN’S
ISCHMIC
CONTRATURE
73. CAUSES
• Supracondylar fracture of
the humerus.
• IV fluid
• chemotherapy.
• Burns.
• Closedforearmcrush
injuries.
• Tight plaster after reduction
of fracture.
Burns
Supracondylar fracture
74. PATHOGENESIS
• Injury to Brachial artery
• Followedby infarction of
forearm Flexor Muscles
• And injuryto mediannerve &
ulnar nerve bothby
ischaemia & infarction
• Followed by asepticmuscles
necrosis
• & fibrosis of flexor muscles of
forearmfollowedby
Contracture
Features
75. CLINICALFEATURES
• Acute phase:
• Pain(persistent pain
in forearm, hand,
fingers—ominous
symptom).
• Pallor
• Puffiness(due to
oedema).
76. • Pulseless(absence of
radial pulse; but its
presence does not rule out
theonset of impending
contracture).
• Paresis
• Late phase
• Deformity Deformity
(due to injury to
median nerve)
• Wrist joint extended.
• Extended
metacarpophalangeal
joints.
• Flexed interphalangeal
joints.
Pulseless
77. • Volkmann’s sign:
• In early stage, the
fingers can be
extendedat the
interphalangeal
joints, only when the
wrist is flexed fully.
• The fingers tendto
flex if any attempt to
extend the wrist is
made
Volkmann’s sign
78. TREATMENT
• In acutephase:
• Removal of plastic
cast appliedafter
fracture reduction.
• Correctionof
fracture.
• Exposure of brachial
arteryand
applicationof 2.5%
papaverine sulphate
to relieve the spasmif
any.
79. • Suture of arterial tear
if present, oftenwith
placement of arterial
graft.
• Lateral incisionover
the deepfascia of
forearmis placedto
decompress the
oedema.
• In late phase (once
deformity occurs):
• Physiotherapy
• Dynamicsplints.
• Max-Page operation:
Releaseof flexor muscles
(forearmmuscles) from
their origins fromthe
bone and allowing it
slidedown until full
extension.
81. • Excision of fibrous
tissue and damaged
muscles along with
tendon transfer.
• Arthrodesis.
REFERENCE
1. SRB's Manual of Surgery
by SriramBhatM
2. A Manual on Clinical
Surgeryby Das
3. A Concise textbookof
Surgeryby Das