Purpura hemorrhagica is a rare complication of equine strangles that is caused by bleeding from capillaries, resulting in red spots on the skin and swelling. It is more common in younger horses and can be fatal. The immune system damages blood vessel walls, causing leakage of blood into tissues and swelling of the head, legs, and underbelly. Severe cases can involve skin necrosis and sloughing. Treatment focuses on resolving underlying infections, using corticosteroids and diuretics. Prognosis depends on severity, and complications can be fatal.
Felon or Terminal Pulp Infection is defined as an abscess of pulp of finger. It may involve the terminal , middle or proximal pulp space, sometimes distal pulp space.
This document discusses ectodermal dysplasia syndrome (EDS), a heterogeneous group of inherited disorders that affect ectodermal tissues like skin, hair, nails, sweat glands, and teeth. It describes two main types - hypohidrotic EDS and hidrotic EDS. Hypohidrotic EDS is characterized by hypohidrosis, anomalous dentition, onychodysplasia, and hypotrichosis. It can cause facial abnormalities, dry skin, intellectual disability, and other issues. Hidrotic EDS causes nail dystrophy, sparse hair, and palmoplantar changes. The document outlines clinical features and manifestations of both conditions, including oral findings like hypodontia and
Week 5 Powerpoint for Supplemental Video (skin)stanbridge
This document discusses skin lesions and how to describe them. It notes that rashes can be difficult to diagnose as they vary in appearance and can change with scratching or treatment. It describes common lesion characteristics like macules, papules, vesicles, and bullae. Lesions can be combinations of types. Descriptions should note color, size, shape, and other details. Some dangerous rashes include petechial, Stevens-Johnson Syndrome, and toxic shock syndrome rashes. The skin provides important clues about a person's health.
1. The document summarizes various systemic diseases that can manifest themselves through changes in the skin, including hyperlipidemia, gastrointestinal diseases, carcinoid syndrome, diabetes mellitus, liver disease, HIV/AIDS, sarcoidosis, mastocytosis, amyloidosis, acromegaly, hypopituitarism, hypothyroidism, hyperthyroidism, Cushing's syndrome, porphyria, rheumatoid arthritis, Reiter's disease, and myelodysplastic syndrome.
2. Common skin manifestations of these diseases include xanthelasma, xanthoma, erythema nodosum, pyoderma gangrenosum, cutaneous metastases, recurrent skin infections, nec
Lymphadenopathy is the enlargement of lymph nodes, which can be caused by inflammation (lymphadenitis) or infection. There are different types of lymphadenopathy including localized, generalized, and persistent generalized lymphadenopathy lasting a long time without an apparent cause. Certain diseases are characterized by lymphadenopathy and swelling of lymph nodes, such as bubonic plague, infectious mononucleosis, cutaneous anthrax, and trypanosomiasis. The document lists many potential differential diagnoses that can cause lymphadenopathy, including various infections, leukemias, cystic fibrosis, and autoimmune diseases.
Purpura hemorrhagica is a rare complication of equine strangles that is caused by bleeding from capillaries, resulting in red spots on the skin and swelling. It is more common in younger horses and can be fatal. The immune system damages blood vessel walls, causing leakage of blood into tissues and swelling of the head, legs, and underbelly. Severe cases can involve skin necrosis and sloughing. Treatment focuses on resolving underlying infections, using corticosteroids and diuretics. Prognosis depends on severity, and complications can be fatal.
Felon or Terminal Pulp Infection is defined as an abscess of pulp of finger. It may involve the terminal , middle or proximal pulp space, sometimes distal pulp space.
This document discusses ectodermal dysplasia syndrome (EDS), a heterogeneous group of inherited disorders that affect ectodermal tissues like skin, hair, nails, sweat glands, and teeth. It describes two main types - hypohidrotic EDS and hidrotic EDS. Hypohidrotic EDS is characterized by hypohidrosis, anomalous dentition, onychodysplasia, and hypotrichosis. It can cause facial abnormalities, dry skin, intellectual disability, and other issues. Hidrotic EDS causes nail dystrophy, sparse hair, and palmoplantar changes. The document outlines clinical features and manifestations of both conditions, including oral findings like hypodontia and
Week 5 Powerpoint for Supplemental Video (skin)stanbridge
This document discusses skin lesions and how to describe them. It notes that rashes can be difficult to diagnose as they vary in appearance and can change with scratching or treatment. It describes common lesion characteristics like macules, papules, vesicles, and bullae. Lesions can be combinations of types. Descriptions should note color, size, shape, and other details. Some dangerous rashes include petechial, Stevens-Johnson Syndrome, and toxic shock syndrome rashes. The skin provides important clues about a person's health.
1. The document summarizes various systemic diseases that can manifest themselves through changes in the skin, including hyperlipidemia, gastrointestinal diseases, carcinoid syndrome, diabetes mellitus, liver disease, HIV/AIDS, sarcoidosis, mastocytosis, amyloidosis, acromegaly, hypopituitarism, hypothyroidism, hyperthyroidism, Cushing's syndrome, porphyria, rheumatoid arthritis, Reiter's disease, and myelodysplastic syndrome.
2. Common skin manifestations of these diseases include xanthelasma, xanthoma, erythema nodosum, pyoderma gangrenosum, cutaneous metastases, recurrent skin infections, nec
Lymphadenopathy is the enlargement of lymph nodes, which can be caused by inflammation (lymphadenitis) or infection. There are different types of lymphadenopathy including localized, generalized, and persistent generalized lymphadenopathy lasting a long time without an apparent cause. Certain diseases are characterized by lymphadenopathy and swelling of lymph nodes, such as bubonic plague, infectious mononucleosis, cutaneous anthrax, and trypanosomiasis. The document lists many potential differential diagnoses that can cause lymphadenopathy, including various infections, leukemias, cystic fibrosis, and autoimmune diseases.
Acute herpetic gingivostomatitis (AHG) is a viral infection of the oral mucosa caused by the herpes simplex virus type 1. It occurs most frequently in infants and children under 6 years old and presents with diffuse erythema and edema of the gums, as well as clusters of vesicles dispersed throughout the mouth, lips, palate, and tongue. The symptoms include generalized oral soreness and fever, and the full course of the disease is typically 7-10 days. After the primary infection subsides, the virus can remain latent in nerve tissues and potentially reactivate to cause cold sores.
This document discusses cutaneous manifestations of gastrointestinal diseases, specifically liver diseases and inflammatory bowel diseases. For liver diseases, it describes pigmentary changes like jaundice, vascular changes like spider angiomas, coagulation defects causing bruising, and nail changes like clubbing. Specific conditions like hepatitis B and C can cause various rashes, and primary biliary cirrhosis causes pruritus. For inflammatory bowel diseases, it mentions disorders from direct extension like perianal abscesses, secondary malnutrition issues, and associated conditions like erythema nodosum. Pyoderma gangrenosum and aphthous ulcers are also discussed.
This document discusses various skin lesions and oral manifestations that can occur due to viral, bacterial, fungal infections and autoimmune diseases.
It provides details on Herpes Zoster (Shingles), Hand Foot and Mouth disease caused by viruses. Bacterial infections like Tuberculosis and Syphilis are explained. Candidiasis is discussed as the common fungal infection causing thrush in the oral cavity. Skin conditions and oral lesions associated with HIV/AIDS are summarized. Treatment options for many of these conditions are also mentioned.
skin is an organ where internal disorders are manifested. some are early signs, some are late signs, some may be the only manifestation. they can result in diagnostic dilemma.
The document discusses various topics related to the structure and function of the human eye including: a normal intraocular pressure range of 12-22 mm Hg; conjunctivitis which causes pink eye from infection, allergies or irritants; retinal detachment which is an emergency condition caused by diabetic neovascularization or trauma; pterygium which refers to a benign growth on the conjunctiva commonly on the nasal side; trachoma which is an infectious disease caused by Chlamydia trachomatis; and trichiasis which involves abnormally positioned eyelashes growing back toward the eye.
Cutaneous Presentations Of Systemic DiseasesLEDocDave
1. The document discusses various cutaneous manifestations of systemic diseases, including bacterial infections like gonorrhea, fungal infections like candidiasis, and various cancers that can present with lesions on the skin, nails, or mucous membranes.
2. Specific conditions covered include subacute bacterial endocarditis, various forms of leukemia, graft-vs-host disease, lichen planus, dermatomyositis, acanthosis nigricans, and others that have characteristic skin findings and associations with internal malignancies.
3. Many infectious diseases are also detailed, such as syphilis, meningococcemia, tuberculosis, and their cutaneous presentations. Internal conditions like diabetes and pancreatic diseases can
DIFFERENTIAL DIAGNOSIS OF SUBMANDIBULAR SWELLINGS FOR UGsANJANA B.S.
The document discusses the differential diagnosis of submandibular swellings. It describes several potential causes: (1) inflammatory disorders like sialadenitis caused by viruses like mumps or bacteria, (2) obstructions from salivary stones which cause pain during eating, (3) rare tumors that present as slow-growing lumps, (4) enlarged lymph nodes due to infection or other illnesses, (5) Sjogren's syndrome which causes dry eyes and mouth from gland inflammation, and (6) plunging ranulas cysts originating from sublingual or submandibular glands that appear as neck masses. A thorough examination is needed to determine the cause as treatments vary significantly depending on the diagnosis.
Leptospirosis is an infectious disease caused by pathogenic leptospires. It can present as a mild influenza-like illness or a severe form known as Weil's syndrome characterized by jaundice, renal dysfunction, and hemorrhagic diathesis. Leptospires are spirochete bacteria that can enter the body through breaks in the skin or mucous membranes and spread systemically, multiplying in the blood and tissues and potentially affecting multiple organs. Treatment involves antibiotics such as doxycycline or penicillin depending on disease severity.
A hyperlinked and animated PowerPoint presentation on leprosy or Hansen's Disease. A bacterial disease prevalent in south Asian countries, Africa and Brazil.
Hope you will like it.
Please do share with your friends
Cutaneous manifestations are common in HIV patients, occurring in over 90% of cases. They can represent the first signs of HIV infection and have prognostic significance. Skin conditions in HIV patients often present atypically with lesions in unusual sites, atypical morphology, being more extensive or not responding to conventional treatments. Common manifestations include generalized rashes, oral/genital ulcers, seborrheic dermatitis, psoriasis, papulopruritic eruptions, eosinophilic folliculitis, granuloma annulare, bacterial/viral infections like herpes, fungal infections, and Kaposi sarcoma. It is important to consider HIV when patients present with rare or unusual skin
Streptococcus bacteria can cause various infections in humans including skin infections, strep throat, sinus infections, and pneumonia. They appear in chains and are found on the skin, in the oral cavity, and respiratory tract. Cellulitis is a localized skin infection caused by streptococcus bacteria invading through a cut or scrape, causing redness, swelling, and pain in the deepest skin layers, especially on the face or legs. Signs include fever, chills, and general illness. While antibiotics are usually effective, abscesses also require drainage to resolve regardless of the specific bacteria.
This document discusses vesiculobullous disorders in children. It begins with an introduction and overview of primary vesiculobullous disorders including vesicles, bullae and pustules. It then discusses specific disorders like pemphigus vulgaris, pemphigoid, and herpes infections. Clinical features, etiology, pathogenesis, treatment and prognosis are described for conditions like erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis and various forms of epidermolysis bullosa. Management involves addressing infections, wound care and supportive measures.
Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum. It has several stages including primary, secondary, latent, and tertiary syphilis. Primary syphilis presents as a painless chancre 1-3 weeks after infection. Secondary syphilis occurs 1-6 months later and involves a rash, fever, and mucous patches. Latent syphilis involves no symptoms but positive blood tests, and can last years. Tertiary syphilis damages internal organs if untreated and can cause blindness, deafness, or paralysis. Congenital syphilis is transmitted from mother to child during pregnancy or birth and can cause deformities or death of the baby if
This document discusses cutaneous manifestations associated with Covid-19 infection seen in patients as well as healthcare workers. It notes that rashes are one of the most common symptoms seen in Covid patients, with the most frequent being maculopapular rash, urticarial rash, and pseudo-chillblain lesions. It also discusses the impact of Covid-19 on treatment of pre-existing skin conditions requiring immunosuppression. The document provides guidance on management of these patients during the pandemic and lists cutaneous side effects of potential Covid treatments. It concludes with recommendations for skin and mucosal protection in healthcare workers to prevent dermatitis from extensive hand hygiene and prolonged PPE use.
Syphilis is caused by the bacterium Treponema pallidum and is transmitted sexually, from mother to fetus, or rarely through other means. It progresses through primary, secondary, latent, and tertiary stages if left untreated. Primary syphilis presents as a painless chancre at the infection site while secondary syphilis causes a rash, fever, and mucous patches. Latent syphilis involves positive blood tests without symptoms. Tertiary syphilis can damage internal organs. Treatment involves penicillin or alternatives like doxycycline for non-pregnant patients and higher dose penicillin for pregnant patients and congenital cases.
Erythema nodosum is an inflammatory skin disorder causing tender red nodules, usually on the lower legs, in response to infections, medications, pregnancy, or other conditions. The nodules develop over 1-2 weeks, becoming hard and painful before resolving without treatment. Investigations like throat cultures and chest x-rays may be used to identify underlying causes like strep infection or sarcoidosis. Treatment focuses on relieving symptoms with NSAIDs, leg elevation, or topical steroids.
This document discusses salivary gland infections. It notes that salivary gland infections can be viral, bacterial, or fungal, with viruses being the most common cause. The parotid glands are more commonly infected than the submandibular glands. Sialadenitis refers to inflammation of the salivary glands. Mumps is a common viral cause of sialadenitis that infects the parotid glands. Bacterial infections are usually due to retrograde spread of bacteria via the salivary ducts when salivary flow is reduced. Actinomycosis is a rare fungal infection that can affect the salivary glands. Diagnosis involves clinical examination and sometimes
This document summarizes various microbial diseases that can affect the skin and eyes. It discusses bacterial infections caused by Staphylococcus and Streptococcus such as impetigo, scalded skin syndrome, and necrotizing fasciitis. Viral skin diseases mentioned include warts, smallpox, chickenpox, shingles, and herpes. Fungal infections of the skin like candidiasis and cutaneous mycoses are also covered. The document concludes by examining common eye infections including conjunctivitis, gonococcal ophthalmia, and trachoma.
Gangrene is tissue death caused by a lack of blood supply. It commonly affects the extremities. There are several types including dry, wet, gas, and necrotizing gangrene. Peripheral vascular diseases involve a narrowing of the blood vessels outside of the heart and brain, reducing blood flow. Common causes are diabetes, smoking, and high blood pressure. Symptoms include pain, skin ulcers, and cold skin. Treatment involves managing underlying conditions, medications, surgery, and hyperbaric oxygen therapy.
Hand infection is the infection caused in hand , since hand contains neurovascular bundles, muscles, bones, and ligaments.
It includes
1. Acute Paronychia
2.Chronic Paronychia
3.Terminal pulp space infection ( felon)
4.subungal infection
5. Web space infecion
6. Mid palmar space infection
7.Thenar space infection
8. Deep palmar abscess
9. Acute suppurative tenosynovitis
11. Chronic Tenosynovitis
12. Lymphangitis of the hand
13. Arthritis of hand joints
14. Subcuticular abscess
This document provides an overview of various viral skin infections. It discusses how viruses can mutate over time through drift or shift. It then examines several specific viruses in more detail, including herpes simplex virus, varicella zoster virus, pityriasis rosea, and poxviruses. For each virus, it outlines the pathophysiology, clinical features, diagnosis, and management. The goal is to educate on the different viral infections that can present in dermatology.
Acute herpetic gingivostomatitis (AHG) is a viral infection of the oral mucosa caused by the herpes simplex virus type 1. It occurs most frequently in infants and children under 6 years old and presents with diffuse erythema and edema of the gums, as well as clusters of vesicles dispersed throughout the mouth, lips, palate, and tongue. The symptoms include generalized oral soreness and fever, and the full course of the disease is typically 7-10 days. After the primary infection subsides, the virus can remain latent in nerve tissues and potentially reactivate to cause cold sores.
This document discusses cutaneous manifestations of gastrointestinal diseases, specifically liver diseases and inflammatory bowel diseases. For liver diseases, it describes pigmentary changes like jaundice, vascular changes like spider angiomas, coagulation defects causing bruising, and nail changes like clubbing. Specific conditions like hepatitis B and C can cause various rashes, and primary biliary cirrhosis causes pruritus. For inflammatory bowel diseases, it mentions disorders from direct extension like perianal abscesses, secondary malnutrition issues, and associated conditions like erythema nodosum. Pyoderma gangrenosum and aphthous ulcers are also discussed.
This document discusses various skin lesions and oral manifestations that can occur due to viral, bacterial, fungal infections and autoimmune diseases.
It provides details on Herpes Zoster (Shingles), Hand Foot and Mouth disease caused by viruses. Bacterial infections like Tuberculosis and Syphilis are explained. Candidiasis is discussed as the common fungal infection causing thrush in the oral cavity. Skin conditions and oral lesions associated with HIV/AIDS are summarized. Treatment options for many of these conditions are also mentioned.
skin is an organ where internal disorders are manifested. some are early signs, some are late signs, some may be the only manifestation. they can result in diagnostic dilemma.
The document discusses various topics related to the structure and function of the human eye including: a normal intraocular pressure range of 12-22 mm Hg; conjunctivitis which causes pink eye from infection, allergies or irritants; retinal detachment which is an emergency condition caused by diabetic neovascularization or trauma; pterygium which refers to a benign growth on the conjunctiva commonly on the nasal side; trachoma which is an infectious disease caused by Chlamydia trachomatis; and trichiasis which involves abnormally positioned eyelashes growing back toward the eye.
Cutaneous Presentations Of Systemic DiseasesLEDocDave
1. The document discusses various cutaneous manifestations of systemic diseases, including bacterial infections like gonorrhea, fungal infections like candidiasis, and various cancers that can present with lesions on the skin, nails, or mucous membranes.
2. Specific conditions covered include subacute bacterial endocarditis, various forms of leukemia, graft-vs-host disease, lichen planus, dermatomyositis, acanthosis nigricans, and others that have characteristic skin findings and associations with internal malignancies.
3. Many infectious diseases are also detailed, such as syphilis, meningococcemia, tuberculosis, and their cutaneous presentations. Internal conditions like diabetes and pancreatic diseases can
DIFFERENTIAL DIAGNOSIS OF SUBMANDIBULAR SWELLINGS FOR UGsANJANA B.S.
The document discusses the differential diagnosis of submandibular swellings. It describes several potential causes: (1) inflammatory disorders like sialadenitis caused by viruses like mumps or bacteria, (2) obstructions from salivary stones which cause pain during eating, (3) rare tumors that present as slow-growing lumps, (4) enlarged lymph nodes due to infection or other illnesses, (5) Sjogren's syndrome which causes dry eyes and mouth from gland inflammation, and (6) plunging ranulas cysts originating from sublingual or submandibular glands that appear as neck masses. A thorough examination is needed to determine the cause as treatments vary significantly depending on the diagnosis.
Leptospirosis is an infectious disease caused by pathogenic leptospires. It can present as a mild influenza-like illness or a severe form known as Weil's syndrome characterized by jaundice, renal dysfunction, and hemorrhagic diathesis. Leptospires are spirochete bacteria that can enter the body through breaks in the skin or mucous membranes and spread systemically, multiplying in the blood and tissues and potentially affecting multiple organs. Treatment involves antibiotics such as doxycycline or penicillin depending on disease severity.
A hyperlinked and animated PowerPoint presentation on leprosy or Hansen's Disease. A bacterial disease prevalent in south Asian countries, Africa and Brazil.
Hope you will like it.
Please do share with your friends
Cutaneous manifestations are common in HIV patients, occurring in over 90% of cases. They can represent the first signs of HIV infection and have prognostic significance. Skin conditions in HIV patients often present atypically with lesions in unusual sites, atypical morphology, being more extensive or not responding to conventional treatments. Common manifestations include generalized rashes, oral/genital ulcers, seborrheic dermatitis, psoriasis, papulopruritic eruptions, eosinophilic folliculitis, granuloma annulare, bacterial/viral infections like herpes, fungal infections, and Kaposi sarcoma. It is important to consider HIV when patients present with rare or unusual skin
Streptococcus bacteria can cause various infections in humans including skin infections, strep throat, sinus infections, and pneumonia. They appear in chains and are found on the skin, in the oral cavity, and respiratory tract. Cellulitis is a localized skin infection caused by streptococcus bacteria invading through a cut or scrape, causing redness, swelling, and pain in the deepest skin layers, especially on the face or legs. Signs include fever, chills, and general illness. While antibiotics are usually effective, abscesses also require drainage to resolve regardless of the specific bacteria.
This document discusses vesiculobullous disorders in children. It begins with an introduction and overview of primary vesiculobullous disorders including vesicles, bullae and pustules. It then discusses specific disorders like pemphigus vulgaris, pemphigoid, and herpes infections. Clinical features, etiology, pathogenesis, treatment and prognosis are described for conditions like erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis and various forms of epidermolysis bullosa. Management involves addressing infections, wound care and supportive measures.
Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum. It has several stages including primary, secondary, latent, and tertiary syphilis. Primary syphilis presents as a painless chancre 1-3 weeks after infection. Secondary syphilis occurs 1-6 months later and involves a rash, fever, and mucous patches. Latent syphilis involves no symptoms but positive blood tests, and can last years. Tertiary syphilis damages internal organs if untreated and can cause blindness, deafness, or paralysis. Congenital syphilis is transmitted from mother to child during pregnancy or birth and can cause deformities or death of the baby if
This document discusses cutaneous manifestations associated with Covid-19 infection seen in patients as well as healthcare workers. It notes that rashes are one of the most common symptoms seen in Covid patients, with the most frequent being maculopapular rash, urticarial rash, and pseudo-chillblain lesions. It also discusses the impact of Covid-19 on treatment of pre-existing skin conditions requiring immunosuppression. The document provides guidance on management of these patients during the pandemic and lists cutaneous side effects of potential Covid treatments. It concludes with recommendations for skin and mucosal protection in healthcare workers to prevent dermatitis from extensive hand hygiene and prolonged PPE use.
Syphilis is caused by the bacterium Treponema pallidum and is transmitted sexually, from mother to fetus, or rarely through other means. It progresses through primary, secondary, latent, and tertiary stages if left untreated. Primary syphilis presents as a painless chancre at the infection site while secondary syphilis causes a rash, fever, and mucous patches. Latent syphilis involves positive blood tests without symptoms. Tertiary syphilis can damage internal organs. Treatment involves penicillin or alternatives like doxycycline for non-pregnant patients and higher dose penicillin for pregnant patients and congenital cases.
Erythema nodosum is an inflammatory skin disorder causing tender red nodules, usually on the lower legs, in response to infections, medications, pregnancy, or other conditions. The nodules develop over 1-2 weeks, becoming hard and painful before resolving without treatment. Investigations like throat cultures and chest x-rays may be used to identify underlying causes like strep infection or sarcoidosis. Treatment focuses on relieving symptoms with NSAIDs, leg elevation, or topical steroids.
This document discusses salivary gland infections. It notes that salivary gland infections can be viral, bacterial, or fungal, with viruses being the most common cause. The parotid glands are more commonly infected than the submandibular glands. Sialadenitis refers to inflammation of the salivary glands. Mumps is a common viral cause of sialadenitis that infects the parotid glands. Bacterial infections are usually due to retrograde spread of bacteria via the salivary ducts when salivary flow is reduced. Actinomycosis is a rare fungal infection that can affect the salivary glands. Diagnosis involves clinical examination and sometimes
This document summarizes various microbial diseases that can affect the skin and eyes. It discusses bacterial infections caused by Staphylococcus and Streptococcus such as impetigo, scalded skin syndrome, and necrotizing fasciitis. Viral skin diseases mentioned include warts, smallpox, chickenpox, shingles, and herpes. Fungal infections of the skin like candidiasis and cutaneous mycoses are also covered. The document concludes by examining common eye infections including conjunctivitis, gonococcal ophthalmia, and trachoma.
Gangrene is tissue death caused by a lack of blood supply. It commonly affects the extremities. There are several types including dry, wet, gas, and necrotizing gangrene. Peripheral vascular diseases involve a narrowing of the blood vessels outside of the heart and brain, reducing blood flow. Common causes are diabetes, smoking, and high blood pressure. Symptoms include pain, skin ulcers, and cold skin. Treatment involves managing underlying conditions, medications, surgery, and hyperbaric oxygen therapy.
Hand infection is the infection caused in hand , since hand contains neurovascular bundles, muscles, bones, and ligaments.
It includes
1. Acute Paronychia
2.Chronic Paronychia
3.Terminal pulp space infection ( felon)
4.subungal infection
5. Web space infecion
6. Mid palmar space infection
7.Thenar space infection
8. Deep palmar abscess
9. Acute suppurative tenosynovitis
11. Chronic Tenosynovitis
12. Lymphangitis of the hand
13. Arthritis of hand joints
14. Subcuticular abscess
This document provides an overview of various viral skin infections. It discusses how viruses can mutate over time through drift or shift. It then examines several specific viruses in more detail, including herpes simplex virus, varicella zoster virus, pityriasis rosea, and poxviruses. For each virus, it outlines the pathophysiology, clinical features, diagnosis, and management. The goal is to educate on the different viral infections that can present in dermatology.
The document discusses sepsis and related syndromes. It defines sepsis, sepsis syndrome, severe sepsis, and septic shock based on symptoms and signs of infection and organ dysfunction. Common causes include bacterial infections like Staphylococcus aureus and gram-negative rods. Specific syndromes discussed include staphylococcal and streptococcal toxic shock syndromes caused by bacterial toxins, and increased risk of overwhelming sepsis in asplenic patients. Meningococcemia, caused by Neisseria meningitidis, is also described as potentially fatal if not treated promptly due to endotoxin effects and shock.
Cellulitis is a spreading infection of subcutaneous &Fascial planes
Oedema gives rise to soft pitting, while if pus is present ,induration can always be felt
Dracunculiasis and Arthropod brone infectionSURYA PRAKASH
The document discusses dracunculiasis (Guinea worm disease), a vector-borne parasitic infection caused by Dracunculus medinensis. It is transmitted by drinking water contaminated with infected water fleas. Symptoms include blistering skin and a burning sensation as the worm emerges. Diagnosis is usually by visualizing the worm exiting the body. Treatment involves slowly removing the worm and using analgesics for pain. Prevention relies on improving access to clean drinking water to eliminate transmission.
Viral skin diseases are common and include infections caused by herpes simplex virus, varicella zoster virus, and human papillomavirus. Herpes simplex virus causes lesions such as cold sores, genital herpes, and eczema herpeticum. Varicella zoster virus causes chickenpox and shingles. Human papillomavirus causes warts, including common warts, flat warts, plantar warts, and genital warts. These viral infections are generally self-limiting but can be treated with antivirals to reduce symptoms and duration of infection.
This document discusses ulcerative and inflammatory lesions of the oral cavity. It focuses on aphthous ulcers (canker sores), herpesvirus infections, oral candidiasis, and lesions seen in AIDS patients such as Kaposi's sarcoma. Aphthous ulcers are common, painful ulcers caused by various triggers that typically resolve within a few weeks. Herpesvirus infections cause cold sores and fever blisters via virus reactivation. Oral candidiasis (thrush) afflicts those with weakened immunity. Lesions in AIDS patients include opportunistic infections and Kaposi's sarcoma.
This document discusses opportunistic mycoses caused by fungi that are normally harmless but can cause infections in immunocompromised individuals. It focuses on aspergillosis, candidiasis, and cryptococcosis. Aspergillosis is caused by the fungus Aspergillus and can infect the lungs, sinuses, and other organs. Candidiasis is a common infection caused by Candida yeasts that can appear in the mouth, throat, skin, or vagina. Cryptococcosis is primarily caused by Cryptococcus neoformans and usually infects the lungs and brain, especially in people with HIV/AIDS.
Leprosy is a chronic infectious disease caused by Mycobacterium leprae. It is characterized by lesions of the peripheral nerves, skin, and nasal mucosa. There are different clinical classifications of leprosy based on immune response and bacterial load, ranging from tuberculoid leprosy with few bacteria and strong immune response to lepromatous leprosy with many bacteria and weak immune response. Without treatment, leprosy can cause permanent damage, especially to the hands, feet, and face.
1. Primary herpetic stomatitis is caused by the herpes simplex virus, usually type 1. It causes painful vesicles and ulcers on the oral mucosa. Recurrent infections usually manifest as herpes labialis.
2. Herpes labialis (cold sores) occurs during viral reactivation, often triggered by factors like illness, sun exposure, or stress. Treatment includes antivirals.
3. Herpetic whitlow is a contagious infection of the fingers that can occur in dental professionals exposed to oral herpes lesions.
Ulcerative & inflammatory diseases of oral cavity i nMohammad Manzoor
This document summarizes several ulcerative and inflammatory lesions of the oral cavity, including aphthous ulcers, herpesvirus infections, oral candidiasis, and Kaposi sarcoma in AIDS patients. Aphthous ulcers are the most common oral disease, appearing as small, painful ulcers, usually resolving within a few weeks but often recurring. Herpesvirus infections cause cold sores or fever blisters via reactivation from latency in ganglia. Oral candidiasis is caused by overgrowth of the fungus Candida albicans when protective mechanisms are impaired. Kaposi sarcoma associated with AIDS may present as purpuric discolorations or nodular oral masses.
The document provides a differential diagnosis for various ulcerative and eschar-forming skin lesions. It describes the key clinical features of cutaneous anthrax including a painless ulcer covered by a black eschar surrounded by disproportionate edema. Cutaneous leishmaniasis presents as a slowly evolving papule to ulcerative lesion with possible lymphangitis. Cat-scratch disease causes regional lymphadenopathy after a papule or vesicle at the inoculation site.
This document provides information about three skin conditions: pityriasis rosea, psoriasis, and lichen planus. It defines each condition and discusses their causes, types, clinical features, differential diagnosis, investigations, and treatment options. Pityriasis rosea causes an acute rash mainly affecting young adults. Psoriasis is a chronic inflammatory skin condition affecting the scalp, elbows, knees and other areas. Lichen planus causes irritation and swelling of the skin, hair, nails and mucous membranes in various forms. The document provides details on diagnosing and managing each condition.
Psoriasis and Management in Primary CareKochi Chia
1. Psoriasis is a chronic, immune-mediated skin disorder characterized by patches of abnormal skin that are typically red, itchy, and scaly. It occurs worldwide and has various clinical subtypes defined by the appearance of the rashes.
2. The pathogenesis of psoriasis involves an interplay between immune system dysfunction, epidermal keratinocyte hyperproliferation, and vascular changes. Genetic and environmental factors contribute to its development.
3. Psoriasis is associated with increased risks of comorbidities like psoriatic arthritis, cardiovascular disease, and metabolic syndrome. Treatment involves topical agents for mild cases and progresses to phototherapy, systemic drugs, and bi
Raynaud’s Phenomenon used to describe episodic events which represent vasoconstriction of digital arteries, precapillary arterioles and arteriovenous shunts.
This document discusses cytomegalovirus (CMV) infection. It notes that CMV transmission occurs through direct contact with infected white blood cells or blood products. In organ transplant recipients, CMV can be transmitted through the donor organ. CMV infection is usually asymptomatic but can cause mononucleosis-like symptoms. It establishes latency after initial exposure. CMV infection most commonly involves the eyes, gastrointestinal tract, and mucocutaneous sites in immunocompromised people like those with AIDS. Treatment involves antiviral medications like ganciclovir or valganciclovir.
- Herpes simplex virus types 1 and 2 are common oral viral infections, usually transmitted via saliva or direct contact. Both viruses establish latency in ganglia. HSV-1 typically causes oral lesions while HSV-2 typically causes genital lesions.
- Varicella zoster virus causes chickenpox in children and shingles in adults via reactivation. It establishes latency in ganglia.
- Epstein-Barr virus causes infectious mononucleosis, commonly known as "mono" or "kissing disease". It is transmitted through saliva and causes fever, lymphadenopathy and pharyngitis.
Infective endocarditis is a condition where the inner lining of the heart (endocardium) becomes inflamed due to a bacterial or fungal infection. It often involves the heart valves and can cause growths called vegetations that can break off and travel to other organs. It is classified based on the causative organism (bacteria, fungus) and whether the person has a normal or abnormal heart/valves. Common symptoms include fever, heart murmur, skin lesions, and potential complications involving the brain, lungs, kidneys, and spleen. Diagnosis involves blood cultures, echocardiography, and the modified Duke criteria.
STRICTURE URETHRA
CLASSIICATION -I
I: Aetiologically.
2. Congenital.
3. Inflammatory:
Post-gonococcal
is most common
Gonococcal stricture occurs one year after infection.
Retention develops only 10–15 years later.
Rupture of the anterior urethra is usually caused by a fall astride a projecting object. Clinical features include blood in the urethra, a perineal hematoma, and retention of urine. Treatment involves gentle catheterization in the operating room. If catheterization is not possible, open surgical repair of the tear is performed through a perineal incision. Complications can include infection and stricture formation.
RENAL CALCULUS AETIOLOGY
Males- radio-opaque gall stones
Females - Radiolucent gall stones
Diet:Vitamin A deficiency
it causes desquamation of epithelium
which acts as a nidus for stone formation.
Climate:
In hot climate urinary solutes will increase with decrease in colloids,
PARAPHIMOSIS
DEFINITION
Inability to place back (cover) the retracted prepucial skin over the glans is called as paraphimosis.
It causes ring like constriction proximal to the corona and prepuceal skin.
HYPOSPADIAS
DEFINITION
It is the most common congenital malformation of urethra wherein external meatus is situated proximal than normal, over the ventral (under) aspect of the penis.
HYDRONEPHROSIS (HN)
DEFINITION
It is an aseptic dilatation of pelvicalyceal system due to partial or intermittent obstruction to the outflow of urine.
AETIOLOGY
unilateral
bilateral.
EPISPADIAS
Here the urethra opens on the dorsum of the penis, proximal to the glans.
COMMON SITES
abdominopenile junction.
It is associated with a dorsal chordee, ectopia vesicae, urinary incontinence, separated pubic bones.
It is uncommon in females.
This document discusses benign prostate hyperplasia (BPH), including its etiology, pathology, clinical features, diagnosis, and treatment. BPH is a non-cancerous enlargement of the prostate that occurs in older men due to an imbalance of hormones. It causes obstruction of the urethra and symptoms like frequent urination, weak urine stream, and retention. Diagnosis involves exams, urine and blood tests, and imaging of the prostate, kidneys, and bladder. Treatment depends on symptoms and complications but may include catheterization, surgery to remove part of the prostate like TURP, or other procedures to relieve blockage.
Varicocele is dilatation and tortuosity of the veins within the scrotum that drain blood from the testicles. It is more common on the left side where the left testicular vein drains directly into the left renal vein. Varicocele can cause increased temperature in the scrotum and impair sperm production. Treatment involves surgical ligation of the affected veins to repair blood flow and potentially improve fertility.
TESTICULAR TUMOURS
PREVALANCE
99% of testicular tumours are malignant.
Life time prevalence of getting testicular tumour is 0.2%.
Very common in Scandinavia; least common inAfrica andAsia.
4 times common in whites than blacks.
ORCHITIS
AETIOLOGY
It is an inflammation of the testis.
It is commonly associated with inflammation ofthe epididymis. Hence, called as epididymo-orchitis.
Orchitis is due to infection through blood, lymphatics or epididymis.
EPIDIDYMITIS,
CAUSES
Inflammation of epididymis is commonly associated with orchitis— epididymo-orchitis.
Nonspecific
viral like mumps.
Bacterial.
Filarial.
Tuberculosis
PERFORATED PEPTIC ULCER
PERFORATION
DEFINITION
It is the terminology used for perforation of duodenal ulcer or gastric ulcer or stomal ulcer.
Otherwise all clinical features and management are similar.
Perforation is common in duodenal ulcer
Mortality is more in gastric ulcer perforation and perforation in elderly
GASTRIC ULCER
AETIOLOGY
It occurs due to imbalance between protective and damaging factors of gastric mucosa.
Atrophic gastritis
duodenogastric bile reflux
gastric stasis
abnormalities in acid and pepsin secretion.
Acid becomes ulcerogenic even to normal gastric mucosa.
CURLING ULCER
DEFINITION
They are acute ulcers which develop after major burns, presenting as pain in epigastric region, vomiting or haematemesis.
Curling’s ulcer occurs when burn injury is more than 35%.
It is observed in the body and fundus not in antrum and duodenum
Congenital (infantile) hypertrophic pyloric stenosis by Dr.K.AmrithaAnilkumarDr. Amritha Anilkumar
CONGENITAL (INFANTILE) HYPERTROPHIC PYLORIC STENOSIS
DEFINITION
It is hypertrophy of musculature of pyloric antrum, especially the circular muscle fibres, causing primary failure of pylorus to relax.
Duodenum is normal.
CARCINOMA STOMACH
INCIDENCE
‘It is the captain of men of death’.
It is more common in Japan—70 per 1,00,000 population.
It is more common in males 2:1.
Decrease incidence in western world
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
3. HANDINFECTION
Definition
• Hand contains
neurovascular bundles,
muscles, bones and
ligaments.
• Infectionmay be due to
minor injuries or blood
borne.
PRICIPITINGCAUSES
• Diabetes
• Immunosuppression
• HIV infection
• Vascular diseases
COMMONORGANISMS
• Staphylococcus aureus-
most common – 90%
• Gram-negative organisms
like
• E. coli
• Klebsiella
• Pseudomonas
4. PATHOLOGY
Infectionspreads faster
↓
Causes oedema due to lax skin
↓
looks like frog hand
↓
Restricted movements of
fingers and hand.
↓
The handfunctions like hook,
pinch, grip, graspare lost.
SYMPTOMS
• Severe pain
• Tenderness withfever.
• Tender palpable
axillary lymphnodes
are oftenpresent
5. TYPESOF HANDINFECTION
1. Acute paronychia.
2. Chronicparonychia.
3. Terminal pulp space
infection(felon).
4. Subungualinfection.
5. Web space infection.
6. Mid-palmar space
infection.
7. Thenarspace infection.
8. Deep palmar abscess.
9. Acutesuppurative
10. tenosynovitis.
11. Chronictenosynovitis
12. Lymphangitis of the
hand.
13. Arthritis of hand joints.
14. Subcuticular abscess
6. INVESTIGATIONS
• Pus culture
• Blood sugar.
• Urine sugar and ketone
bodies.
• Arterial Doppler of the
handif needed.
TREAMENT
• Antibiotictherapy.
• Positionof rest with wrist
slightly abductedand
extended, thumb and
index fingers away (glass-
holding position).
REFERENCE
1. SRB's Manual of Surgery
by SriramBhat M
2. A Manual on Clinical
Surgeryby Das
3. A Concise textbookof
Surgeryby Das
Glass holding position