This document provides information about three skin conditions: pityriasis rosea, psoriasis, and lichen planus. It defines each condition and discusses their causes, types, clinical features, differential diagnosis, investigations, and treatment options. Pityriasis rosea causes an acute rash mainly affecting young adults. Psoriasis is a chronic inflammatory skin condition affecting the scalp, elbows, knees and other areas. Lichen planus causes irritation and swelling of the skin, hair, nails and mucous membranes in various forms. The document provides details on diagnosing and managing each condition.
This is the summary of 80% of the dermatology clinical round with important photos that solidify the important information needed by medical students.
Also in these slides, a summary for STDs and HIV was added near the end including their most special features and the drugs of choice to manage such cases.
Etiology of Leprosy:
A chronic infection caused by Mycobacterium leprae
Acid-fast, rod shaped
Main route of infection:
nasal droplets,
Eating armadillos (south america)
Not very contagious, but close relatives are at high risk of infection
This is the summary of 80% of the dermatology clinical round with important photos that solidify the important information needed by medical students.
Also in these slides, a summary for STDs and HIV was added near the end including their most special features and the drugs of choice to manage such cases.
Etiology of Leprosy:
A chronic infection caused by Mycobacterium leprae
Acid-fast, rod shaped
Main route of infection:
nasal droplets,
Eating armadillos (south america)
Not very contagious, but close relatives are at high risk of infection
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
7. Clinical features
➸The first lesion to appear, or ‘herald patch’is larger than
the subsequent oval pink scaly patches that appear several
days later in crops over subsequent weeks.
➸ These mainly affect the trunk and proximal limbs in a
Christmas tree pattern
➸There may be mild pruritus.
➸ Spontaneous
resolution usually occurs within 6 weeks and recurrences
are rare
9. Investigation
➪None are routinely necessary.
➸ In atypical cases,
■
■ skin scrapings should be taken for mycology and
serological tests for secondary syphilis considered.
10. Treatment
➸An emollient and moderate potency topical corticosteroid
may be prescribed if pruritis is troublesome.
15. Definiton
Psoriasis is a common chronic inflammatory
Papulosqamous eruption with a predilction for
the extensor of limbs ,scalp and nails.
Both sexes are equally affected
16. Causes
A stong genetic compenint
,Precipitating factor include trauma
Streptococcam emfaction
Smoking ,stress, alcohol
Drugs example beta blocking agent, antimalarials,Lthium.
17. Types
The comminest for.
by well demarcated, thickend,de Characterized
by silvery scale. plaque surmounted Deep red
■ Accours in the extenser aspects of limbs,knee,elbow ,
scalp,and ears.
19. Guttate Psoriasis
■ Following a streptococcal throat infaction
■ Red, oval or round plaque appears on the trunk and
proximal limbs
20. Pustular Psoiasis
May be localized or generalized
Localized called palmoplamtar pustulosis
Occurs in adults as crops of ,sterile yellow pustules on the palms
and soles.
Generalized is an unstaple,severe form of psoriesis
Appear at any sit
Fever and malaise are common
21.
22. Erythrodermic psoriesis is a widespread sever with generelized
erythema.it is associated with systemic symptoms if unteated.
Patients ae at risk of fluid and potein loss,poor tempretue control
and infection.
23. Clinical Features of
Psoriasis
to Thick white scale adhering Scalp psorasis
the scalp and hair shaft.
Nail changs are common .
Skin modified by site involvement of flexures .
24.
25.
26. Differential Diagnosis
Chronic plaque psoiasis confined to the palms or soles may closely
to eczema or tinea .
Facial psoiasis difficult to distinguish from seborrhocic eczema .
Guttate psoriasis can simulate pityriasis rosea,pityriasis lichenoides
and secondary
syphilis.
Flexural psoriasis is often misdiagnosed as chronic intetrigo.
28. Treatment
But we can use Psoasis is incurable disease
Many methods to alleviation pain;
Use ceams that contains
CORTICOSTEOIDS
SALICYLIC ACID
Carbamide
Use Methotrexte
Use UVB and PUVA phototheapy
30. PLAY-nus) is a condition that can cause swelling and irritation in
the skin, hair, nails and mucous membranes.
DEFINITION
31. TYPES OF LICHEN
PLANUS:
The clinical presentation of lichen planus
has several forms: actinic (in sun-exposed
areas), annular, atrophic, erosive,
follicular, hypertrophic, linear, pigmented,
and vesicular/bullous
33. CLINICAL
FEATURES
polygonal flat-topped papules . On
clearing, these characteristi- cally leave
post-inflammatory hyperpigmenta- tion .
All races and ages are susceptible,
although the greatest incidence is from 20
to 50 years of age. The cause is unknown
though an immunological basis is
suggested. Some drugs can induce LP-like
eruptions (e.g. antimalarials, heavy metals,
antituberculous therapy). An asso- ciation
with hepatitis C infection has also been
reported in some countries.
34. LP can affect any part of the body but is most commonly seen
symmetrically on the flexor surfaces of the wrists, forearms,
ankles, and lower back. White streaks (Wickham’s striae)
overlie the lesions and are frequently observed on the buccal
mucosa where they form a lacy pattern (Unlike candidiasis,
these cannot be removed by gentle wiping with a swab.
CLINICAL FEATURES
36. Lesions on the lower leg and palmoplantar surfaces are frequently
hyperkeratotic and share features with chronic lichenified eczema () and
scalp involvement produces scarring alopecia. Nail involvement causes
longitu- dinal ridges, variable atrophy, and permanent scarring (pterygium)
Lesions occur at sites of trauma (Köbner phenomenon) Annular lesions
may occur, especially on the penis . Spontaneous recovery is usual within 9
months, but hypertrophic lesions can persist for many years, especially on
the lower legs. An uncommon variant affecting the oro-genital mucosa
typically runs a recalcitrant course. Lichen nitidus is an uncommon variant
of LP which presents with multiple minute grouped papules that typically
affect the forearms, penis, torso, and buttock. It affects children and young
adults
37.
38.
39. DIFFERENTIAL
DIAGNOSIS
Oral lesions may be confused with
candidiasis and frictional hyperkeratosis.
Hyperkeratotic lesions on the palmo-plantar
skin and legs may resemble chronic
eczema.
40. INVESTIGATIO
NS
Histology of active lesions shows lichenoid inflammation
and supports the diagnosis.SPECIAL POINTSA drug
history is important in patients with atypical lichenoid
eruptions to exclude drug- induced disease.
41. TREATMENT
Potent topical, intralesional, or occasionally systemic
corticosteroids are helpful in reducing pruritus. Hypertrophic
lesions may benefit from occlusive dressings. Widespread
acute LP may occasionally require a reducing course of oral
corticosteroids. Other second-line treatments which are used
for severe cutaneous or mucosal LP include acitretin,
phototherapy, and ciclosporin.