This document discusses changing research workflows and the need to transition from open access to open science. It presents several models of the research workflow as multi-cyclic and multi-ordered, with loops for activities like grant writing, experimentation, and publishing. The document outlines three goals for science: being good, efficient, and open. It then analyzes survey data on tools researchers use at different stages of the workflow and how they align with open science principles. The findings suggest a shift towards more open tools and formats.
101 Innovations in scholarly communication - changing research workflowshierohiero
OpenCon webcast December 2015 by Bianca Kramer & Jeroen Bosman. These slides are on the development, availability, use and impact of research tools in all phases of the research cycle, telling us how scholarly communication is changing. CC-BY
The good, the efficient and the open - changing research workflows and the ne...Bianca Kramer
presented at the Geneva Workshop on Innovations in Scholarly Communication (OAI9), Geneva, June 18, 2015
Science is in transition. If all goes well, the transition is towards more open, efficient and honest/reproducible practices. Libraries should move with this change by supporting open science instead of just open access. Building on their successful project "101 innovations in scholarly communication" Jeroen Bosman and Bianca Kramer present their interpretations of what is going on and can be expected in the six phases of the research cycle. They have tested their hypothetical workflows and show how real, day-to-day research workflows are changing from traditional to modern, innovative and experimental. These changes are reflected in tools and sites people use in various phases of that workflow. They might for example change from Web of Science → SPSS → Word+Endnote → Nature → ResearcherID → Impact Factors to Sparrho → ROpenScience+IPythonNotebooks → WriteLateX+Docear → The Winnower → Kudos → Publons+PubPeer. The way new generations of researchers work affects how information will be discovered, re-used, created, shared, communicated and assessed. There are huge opportunities for libraries and other stakeholders to contribute and work with the research community, but only if they are well prepared!
Small steps-big-opportunities-brussels-open-access-week-2015-kramer-bosman sl...Bianca Kramer
Presentation on 'Innovations in scholarly communication' for Open Access 2015 meeting, Brussels, October 21, 2015. Slides in pdf format.
See also http://101innovations.wordpress.com
Invited talk on "why altmetrics?" at the information day "Bibliometrics, Scientometrics & Alternative metrics: which tools for which strategies?”, Association des directeurs et personnels de direction des bibliothèques universitaires et de la documentation (ADBU), 1st April 2015, BULAC, France (Paris)
101 Innovations in scholarly communication - changing research workflowshierohiero
OpenCon webcast December 2015 by Bianca Kramer & Jeroen Bosman. These slides are on the development, availability, use and impact of research tools in all phases of the research cycle, telling us how scholarly communication is changing. CC-BY
The good, the efficient and the open - changing research workflows and the ne...Bianca Kramer
presented at the Geneva Workshop on Innovations in Scholarly Communication (OAI9), Geneva, June 18, 2015
Science is in transition. If all goes well, the transition is towards more open, efficient and honest/reproducible practices. Libraries should move with this change by supporting open science instead of just open access. Building on their successful project "101 innovations in scholarly communication" Jeroen Bosman and Bianca Kramer present their interpretations of what is going on and can be expected in the six phases of the research cycle. They have tested their hypothetical workflows and show how real, day-to-day research workflows are changing from traditional to modern, innovative and experimental. These changes are reflected in tools and sites people use in various phases of that workflow. They might for example change from Web of Science → SPSS → Word+Endnote → Nature → ResearcherID → Impact Factors to Sparrho → ROpenScience+IPythonNotebooks → WriteLateX+Docear → The Winnower → Kudos → Publons+PubPeer. The way new generations of researchers work affects how information will be discovered, re-used, created, shared, communicated and assessed. There are huge opportunities for libraries and other stakeholders to contribute and work with the research community, but only if they are well prepared!
Small steps-big-opportunities-brussels-open-access-week-2015-kramer-bosman sl...Bianca Kramer
Presentation on 'Innovations in scholarly communication' for Open Access 2015 meeting, Brussels, October 21, 2015. Slides in pdf format.
See also http://101innovations.wordpress.com
Invited talk on "why altmetrics?" at the information day "Bibliometrics, Scientometrics & Alternative metrics: which tools for which strategies?”, Association des directeurs et personnels de direction des bibliothèques universitaires et de la documentation (ADBU), 1st April 2015, BULAC, France (Paris)
June 18, 2014
NISO Virtual Conference: Transforming Assessment: Alternative Metrics and Other Trends
Assessing and Reporting Research Impact – A Role for the Library
- Kristi L. Holmes, Ph.D., Director, Galter Health Sciences Library, Northwestern University, Feinberg School of Medicine
June 18, 2014
NISO Virtual Conference: Transforming Assessment: Alternative Metrics and Other Trends
NISO Altmetrics Initiative: A Project Update
- Martin Fenner, Technical Lead for the PLOS Article-Level Metrics project
June 18, 2014
NISO Virtual Conference: Transforming Assessment: Alternative Metrics and Other Trends
Snowball Metrics: University-owned Benchmarking to Reveal Strengths within All Activities
- Dr. Lisa Colledge, Snowball Metrics Program Director, Elsevier
Altmetrics Day Workshop - Internet Librarian International 2014Andy Tattersall
Altmetrics in the Academy - Implementing strategies in the library for better academic engagement, dissemination and measurement
Workshop abstract:
Altmetrics are increasingly gaining support and interest as an alternative way of disseminating and measuring scholarly output. Championed by early career researchers, librarians and information professionals, Altmetrics are to research as MOOCs are to learning. Like MOOCs most still do not understand their potential or how they could fit with or replace existing modes of delivery and assessment.
The first half of the workshop will help delegates gain an understanding of what Altmetrics are and how they can fit within academic library services. The second half of the session will deliver case studies, tools and techniques to help LIS professionals encourage better usage of Altmetrics.
10:00: What do you want from the day? What are your experiences of Altmetrics
10.40am: Altmetrics: an overview or Altmetrics and the day/where are we now?
A history, roadmap, how it fits in
11 am: Altmetrics within institutions: data, IR integration/other tools/library catalogue integration
what data is there? coverage of articles/datasets/other research outputs, mendeley demographic data
case studies of uses
examples of IR integration/motivations
primo/summon/other ones..
altmetric for institutions - integration with existing platforms
free explorer (and we’ll explore the data using this later)
11.30 Break
12.00pm Altmetrics in the Academy - getting academics and librarians on board
12.40 Brainstorming session: Value in Altmetrics: what questions do people have around this? what are their biggest concerns?
13.00 Lunch
2 pm: Getting familiar with the tools - practical session experimenting with the Altmetric explorer - half an hour (set tasks - eg create a list, pull out the most interesting mentions)
Good practice, guidelines, tips
2:45pm: At the coal face - experiences of a researcher using Altmetrics in practice
3.30pm: Break
3.45 pm: Getting mobile, how using mobile apps can help you engage more with Altmetrics
4.05 pm What’s on the horizon? What does the future for scholarly dissemination and impact.
4.40 wrap up and questions
This presentation was provided by Emma Warren-Jones of Scholarcy, during the NISO event "Researcher Behaviors and the Impact of Technology," held on March 25, 2020.
Responsible metrics for research - Jisc Digifest 2016Jisc
Following the publication of the "Metric tide" report - which called for more open and transparent metrics and indicators for research - a panel of experts will discuss the challenges and opportunities from both a policy and more technical level (for example highlighting some of the issues relating to standards and research infrastructure).
Discussion will also focus on implementation challenges (who, how, what and when).
Open Learning Analytics panel at Open Education Conference 2014Stian Håklev
The past five years have seen a dramatic growth in interest in the emerging field of Learning Analytics (LA), and particularly in the potential the field holds to address major challenges facing education. However, much of the work in the learning analytics landscape today is closed in nature, small in scale, tool- or software-centric, and relatively disconnected from other LA initiatives. This lack of collaboration, openness, and system integration often leads to fragmentation where learning data cannot be aggregated across different sources, institutions only have the option to implement "closed" systems, and cross disciplinary research opportunities are limited. Beyond the immediate concerns this fragmentation creates for educators and learners, a closed approach dramatically limits our ability to build upon successes, learn from failures and move beyond the "pockets of excellence (and failures)? approach that typifies much of the educational technology landscape.
The potential benefits of openness as a core value within the learning analytics community are numerous. Learning initiatives could be informed by large scale research projects. Open-source software, such as dashboards and analytics engines, could be available free of licensing costs and easily enhanced by others, and OERs could become more personalized to match learners' needs. Open data sets and reproducible papers could rapidly spread understanding of analytical approaches, enabling secondary analysis and comparison across research projects. To realize this future, leaders within the learning analytics, open technologies (software, standards, etc.), open research (open data, open predictive models, etc.) and open learning (OER, MOOCs, etc.) fields have established a "network of practice" aimed at connecting subject matter experts, projects, organizations and companies working in these domains. As an initial organizing event, these leaders organized an Open Learning Analytics (OLA) Summit directly following the 2014 Learning Analytics and Knowledge (LAK) conference this past March as means to further the goal of establishing "openness' as a core value of the larger learning analytics movement. Additional details on the Summit and those involved can be found at: http://www.prweb.com/releases/2014/04/prweb11754343.htm.
This panel session will bring together several thought leaders from the Open Learning Analytics community who participated in the Summit to facilitate an interactive dialog with attendees on the intersection of learning analytics and open learning, open technologies, open data, and open research. The presenters represent a broad range of experience with institutional analytics projects, an open source development consortium, the sharing of open learner data, and academic research on open learning environments.
Scott Edmunds: Quantifying how FAIR is Hong Kong: The Hong Kong Shareability ...GigaScience, BGI Hong Kong
Scot Edmunds talk at CODATA2019 on Quantifying how FAIR is Hong Kong: The Hong Kong Shareability of Hong Kong University Research Experiment. 19th September 2019 in Beijing
Presented by John Young (ODI) and Laura Harper (Wellcome) at the Public Engagement Workshop, 2-5 Dec. 2008, KwaZulu-Natal South Africa, http://scienceincommunity.wordpress.com/
June 18, 2014
NISO Virtual Conference: Transforming Assessment: Alternative Metrics and Other Trends
Assessing and Reporting Research Impact – A Role for the Library
- Kristi L. Holmes, Ph.D., Director, Galter Health Sciences Library, Northwestern University, Feinberg School of Medicine
June 18, 2014
NISO Virtual Conference: Transforming Assessment: Alternative Metrics and Other Trends
NISO Altmetrics Initiative: A Project Update
- Martin Fenner, Technical Lead for the PLOS Article-Level Metrics project
June 18, 2014
NISO Virtual Conference: Transforming Assessment: Alternative Metrics and Other Trends
Snowball Metrics: University-owned Benchmarking to Reveal Strengths within All Activities
- Dr. Lisa Colledge, Snowball Metrics Program Director, Elsevier
Altmetrics Day Workshop - Internet Librarian International 2014Andy Tattersall
Altmetrics in the Academy - Implementing strategies in the library for better academic engagement, dissemination and measurement
Workshop abstract:
Altmetrics are increasingly gaining support and interest as an alternative way of disseminating and measuring scholarly output. Championed by early career researchers, librarians and information professionals, Altmetrics are to research as MOOCs are to learning. Like MOOCs most still do not understand their potential or how they could fit with or replace existing modes of delivery and assessment.
The first half of the workshop will help delegates gain an understanding of what Altmetrics are and how they can fit within academic library services. The second half of the session will deliver case studies, tools and techniques to help LIS professionals encourage better usage of Altmetrics.
10:00: What do you want from the day? What are your experiences of Altmetrics
10.40am: Altmetrics: an overview or Altmetrics and the day/where are we now?
A history, roadmap, how it fits in
11 am: Altmetrics within institutions: data, IR integration/other tools/library catalogue integration
what data is there? coverage of articles/datasets/other research outputs, mendeley demographic data
case studies of uses
examples of IR integration/motivations
primo/summon/other ones..
altmetric for institutions - integration with existing platforms
free explorer (and we’ll explore the data using this later)
11.30 Break
12.00pm Altmetrics in the Academy - getting academics and librarians on board
12.40 Brainstorming session: Value in Altmetrics: what questions do people have around this? what are their biggest concerns?
13.00 Lunch
2 pm: Getting familiar with the tools - practical session experimenting with the Altmetric explorer - half an hour (set tasks - eg create a list, pull out the most interesting mentions)
Good practice, guidelines, tips
2:45pm: At the coal face - experiences of a researcher using Altmetrics in practice
3.30pm: Break
3.45 pm: Getting mobile, how using mobile apps can help you engage more with Altmetrics
4.05 pm What’s on the horizon? What does the future for scholarly dissemination and impact.
4.40 wrap up and questions
This presentation was provided by Emma Warren-Jones of Scholarcy, during the NISO event "Researcher Behaviors and the Impact of Technology," held on March 25, 2020.
Responsible metrics for research - Jisc Digifest 2016Jisc
Following the publication of the "Metric tide" report - which called for more open and transparent metrics and indicators for research - a panel of experts will discuss the challenges and opportunities from both a policy and more technical level (for example highlighting some of the issues relating to standards and research infrastructure).
Discussion will also focus on implementation challenges (who, how, what and when).
Open Learning Analytics panel at Open Education Conference 2014Stian Håklev
The past five years have seen a dramatic growth in interest in the emerging field of Learning Analytics (LA), and particularly in the potential the field holds to address major challenges facing education. However, much of the work in the learning analytics landscape today is closed in nature, small in scale, tool- or software-centric, and relatively disconnected from other LA initiatives. This lack of collaboration, openness, and system integration often leads to fragmentation where learning data cannot be aggregated across different sources, institutions only have the option to implement "closed" systems, and cross disciplinary research opportunities are limited. Beyond the immediate concerns this fragmentation creates for educators and learners, a closed approach dramatically limits our ability to build upon successes, learn from failures and move beyond the "pockets of excellence (and failures)? approach that typifies much of the educational technology landscape.
The potential benefits of openness as a core value within the learning analytics community are numerous. Learning initiatives could be informed by large scale research projects. Open-source software, such as dashboards and analytics engines, could be available free of licensing costs and easily enhanced by others, and OERs could become more personalized to match learners' needs. Open data sets and reproducible papers could rapidly spread understanding of analytical approaches, enabling secondary analysis and comparison across research projects. To realize this future, leaders within the learning analytics, open technologies (software, standards, etc.), open research (open data, open predictive models, etc.) and open learning (OER, MOOCs, etc.) fields have established a "network of practice" aimed at connecting subject matter experts, projects, organizations and companies working in these domains. As an initial organizing event, these leaders organized an Open Learning Analytics (OLA) Summit directly following the 2014 Learning Analytics and Knowledge (LAK) conference this past March as means to further the goal of establishing "openness' as a core value of the larger learning analytics movement. Additional details on the Summit and those involved can be found at: http://www.prweb.com/releases/2014/04/prweb11754343.htm.
This panel session will bring together several thought leaders from the Open Learning Analytics community who participated in the Summit to facilitate an interactive dialog with attendees on the intersection of learning analytics and open learning, open technologies, open data, and open research. The presenters represent a broad range of experience with institutional analytics projects, an open source development consortium, the sharing of open learner data, and academic research on open learning environments.
Scott Edmunds: Quantifying how FAIR is Hong Kong: The Hong Kong Shareability ...GigaScience, BGI Hong Kong
Scot Edmunds talk at CODATA2019 on Quantifying how FAIR is Hong Kong: The Hong Kong Shareability of Hong Kong University Research Experiment. 19th September 2019 in Beijing
Presented by John Young (ODI) and Laura Harper (Wellcome) at the Public Engagement Workshop, 2-5 Dec. 2008, KwaZulu-Natal South Africa, http://scienceincommunity.wordpress.com/
Science & Community Public Engagement Workshopwellcome.trust
Presented by Clare Matterson (Director of Medicine, Society and History (MSH) at the Wellcome Trust) at the Public Engagement Workshop, 2-5 Dec. 2008, KwaZulu-Natal South Africa, http://scienceincommunity.wordpress.com/
The first step to successfully handling negativity on the Internet is to identify where it's coming from. National Research Center (NRC) describes the four most common sources of Web negativity faced by local governments and shares a few tips on dealing with it.
Sign up for an upcoming Webinar on this topic at www.n-r-c.com/webinars.
Different Media for communicating Science to different groupswellcome.trust
Presented by Derek Fish (Unizul Science Centre, South Africa) at the Public Engagement Workshop, 2-5 Dec. 2008, KwaZulu-Natal South Africa, http://scienceincommunity.wordpress.com/
Created for the National Coalition for Dialogue & Deliberation's 2010 regional events, this must-have resource was developed to share stories and resources with the dialogue and deliberation community, public managers, and anyone else with an interest in public engagement.
Webinar: How NewsCred Does Content Marketing 2017NewsCred
In today's digital landscape, it's harder than ever to get your message out. So how can you ensure that your content marketing efforts will reach your target audience and drive indisputable business results?
In this webinar, NewsCred's Liam Moroney, Program Director, and Heather Eng, Managing Editor, will answer that question. They'll share in-depth details about how NewsCred does content marketing and how you can tailor their best practices to fit your own program.
Helping you shape infrastructure to implement open access efficientlyJisc
This session focused on two projects Jisc monitor and Jisc publications router that will develop prototype solutions and other outputs that point to ways to radically reduce the administrative burden of implementing open access.
Subscribe to the NewsCred Blog: http://newscred.com/subscribe
NewsCred and Getty Images have joined forces to create a guide on how brands can incorporate visual storytelling successfully into their campaigns for maximum impact.
The full guide is available for download here: http://newscred.com/theacademy
Also check out the accompanying interactive microsite here: http://bit.ly/1uEqB27
Closing plenary and keynote from Lauren Sager WeinsteinJisc
Host: Andy McGregor, deputy chief innovation officer, Jisc.
Keynote speaker: Lauren Seger Weinstein, chief data officer at Transport for London.
In our final plenary, we'll hear from Lauren Sager Weinstein.
We'll also be announcing the winners of our edtech start-up competition, as we bring Digifest to a close.
Few could argue that stortelling is a powerful tool to inspire action and change, and to influence thought leaders and decision makers. The shape and delivery of stories has also shifted dramatically in the digital era. Long-form narrative and conventionalism journalism now share a stage with messages 140 characters or images that disappear in seconds after they are opened. There have never been more ways to reach audiences, but it's also never been more difficult to really reach them.
Narrative Image: The How and Why of Visual StorytellingDaniela Molnar
Explores the basics of how images communicate. Looks at various types of visual narratives. Presented to the Guild of Natural Science Illustrators at the 2011 national conference in Olympia, WA on July 12, 2011.
This is a joint presentation by Jeroen Bosman and Bianca Kramer, given during a joint NISO-ICSTI webinar, held on Wednesday, October 26, on Enabling Innovation in Researcher Workflow and Scholarly Communication.
With the progress towards open science, scientific communication is facing a new wave of innovations towards more openness and speed of research publication which will deeply affect the way the peer review function is carried out and the overall role of journals in assuring quality and adding value to manuscripts.
Several initiatives are promoting the generalized adoption of open access preprints as a formal beginning stage of research publication, which has been common since the 90’s in the physics community. And, in the last decade, new ways to carry out the evaluation of manuscripts have emerged either to replace or to improve the traditional methods, which are widely criticized as being slow and expensive in addition to lacking transparency.
Quality nonprofit journals from emerging and developing countries have succeeded to follow the main innovations brought by the Internet. In addition to the technicalities of the digital publishing, there is a wide adoption of Open Access in the international flow of scientific information. The new wave of innovations that affect the peer review function and the changing role of journals pose new challenges to the emerging and developing countries in regard of scientific publishing. The adoption of these innovations is essential for progress of SciELO as a leading open access program to enhance scientific communication.
The scope of this workshop aims at an in-depth analysis and discussion of the state of art and main trends of the peer review function, the modalities of carrying it out as well as of the increasing adoption of mechanisms to speed publication such as preprints and how they affect and potentially renew the role of journals. These recommendations will guide SciELO policies on manuscript evaluation and on the adoption of preprint publications.
Academic Social Networks and Researcher RankingAmanyalsayed
Open science and web scholarly communication
Using Web 2.0 to increase researcher’s ranking
Academic Social Networks (types, services)
Question & Answer service
Sharing your research output through ASN
Researcher measurement (h-index, RG score)
ASN and researchers’ concerns
Changing research workflows at the University of Pretoria (UP) and the CSIR: ...heila1
background of the international survey; the survey: international, UP, CSIR); example of the survey; examples of the results (data); international, UP and CSIR trends; What should the role of the research library be? Changing landscape of scholarly communication; research workflow tools;
A growing number of universities are beginning to require the digital deposit of their thesis and dissertation output in their institutional repositories. At the same time, a growing number of universities as well as research funders are beginning to mandate that all refereed research must be deposited too. This makes for a timely synergy between the practices of the younger and older generation of researchers as the Open Access era unfolds. It also maximizes the uptake, usage and impact of university research input at all stages, as well as providing rich and powerful new metrics to monitor and reward research productivity and impact. It is important to integrate universities' ETD and research output repositories, mandates and metrics as well as to provide the mechanism for those deposits that may need to be made Closed Access rather than Open Access: Repositories need to implement the "email eprint request" Button for all Closed Access Deposits. Any would-be user webwide, having reached the metadata of a Closed Access Deposit can, with one click, request an eprint for research purposes; the author instantly receives an automatic email and can then, again with one click, authorize the automatic emailing of one copy to the user by the repository software. This feature is important for fulfilling immediate research usage needs during any journal-article embargo period, and it also gives the authors of dissertations they hope to publish as books a way to control who has access to the dissertation. Digital dissertations will also benefit from the reference-linking and book-citation metrics that will be provided by harvesters of the distributed institutional repository metadata (which will also include the metadata and reference lists of all university book output). Dissertation downloads as well as eprint-requests will also provide useful new research impact metrics.
Lecture workshop 2 am open access and altmetricsThed van Leeuwen
Traditionally, advanced bibliometrics have been the ‘gold standard’ in research evaluations in many fields. Due to changes in communication patterns in various fields, we now see alternative ways of assessing research appearing on the landscape. One of the major developments in scientific communication patterns is the advent of the Openness movement, through which various activities in academic life become more democratic, transparent, and hopefully fairer. This stretches out to publishing and the costs involved, how data are shared, and how peer review is organized, to name some instances in which the issue of Openness is raised. Of a somewhat more recent nature is the way assessment of scholarly activity is organized, in particular with respect to the way the various audiences with whom scholars are communicating are considered. A new way of looking at research assessment is through the recent ‘alternative metrics’ or also referred to as Altmetrics.
As more classical bibliometrics are under pressure, due to international (DORA-Declaration) and national debates and initiatives (SiT) related to the organization of research assessment in various layers of the science system. This stirs a re-focus from science policy towards alternative ways to assess research performance. In this presentation we will show, by a recent example, how careful we have to be in making choices for metrics in order to support research assessment practices as well science policy decision making.
Michael Markie talks about open reserch publishing platforms | OSFair2017 Workshop
Workshop title: Open Access Models & Platforms
Workshop overview:
What are the emerging models of Open Access for publications? Who should be involved? How are costs distributed over the stakeholders involved? How can OA platforms innovate further to embrace Open Science? This workshop will discuss and showcase the range of models available, including their costs and organisational aspects, to discuss their relative strengths and weaknesses in different academic contexts.
When: DAY 1 - PARALLEL SESSION 1 & 2
New Perspectives in Scholarly Publishing – Potenziale und Möglichkeiten digi...Alexander Grossmann
New Perspectives in Scholarly Publishing – Potenziale und Möglichkeiten digital vernetzter Forschung
Vortrag von Alexander Grossmann, Digital Academics Summit 2017, Leipzig
ScienceOpen: Rethinking Peer Review / Young Academy of ScotlandScienceOpen
Hosted by the RSE Young Academy of Scotland Open Data Working Group
The scholarly publishing paradigm is changing – Open Access, altmetrics, data-mining are increasingly setting new standards. A recent Royal Society conference on “The Future of Scholarly Scientific Communication” called in particular for sweeping reforms to the current system of peer review. The new platform ScienceOpen has taken up the challenge. In order to put the evaluation of research back in the hands of researchers, we are experimenting with new forms of author-mediated pre-publication peer review. Published articles are open for transparent post-publication peer review and versioning to reflect feedback as the scientific community reads, works with, attempts to reproduce and builds on the results. The essential efforts of peer reviewers in this process are recognized with a citable CrossRef DOI for their report. ScienceOpen goes further to extend this open research evaluation process to over 1.5 million aggregated Open Access publications. We are taking advantage of this transitional moment to rethink how scientific communication, and particularly peer review could function in the future, because we believe that scholarly publishing is not an end in itself, but the beginning of a dialogue to move the whole scientific venture forward.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Predicting property prices with machine learning algorithms.pdf
The good, the efficient and the open: changing research workflows and the need to move from Open Access to Open Science
1. (except logo’s)
The good, the efficient, and the open
changing research workflows and the need to move from Open Access to Open Science
Bianca Kramer & Jeroen Bosman , Utrecht University Library
Geneva Workshop on Innovations in Scholarly Communication (OAI9), Geneva, June 18, 2015
@MsPhelps
@jeroenbosman
3. Simple cyclic model of the research workflow
preparation
analysis
writingpublication
outreach
assessment discovery
4. Multi-cyclic model of the research workflow
preparation
analysis
writingpublication
outreach
assessment discovery
Rounds of grant writing
and application
Iterations of
search and reading
Drafting, receiving
comments,rewriting
Submit, peer review,
rejection, resubmitting
Rounds of experiments
and measurements
5. Multi-cyclic model of the research workflow, with
loops
preparation
analysis
writingpublication
outreach
assessment discovery
Rounds of grant writing
and application
Iterations of
search and reading
Drafting, receiving
comments,rewriting
Submit, peer review,
rejection, resubmitting
Rounds of experiments
and measurements
6. A multi-cyclic, multi-ordered
model of the research workflow, with loops
preparation
analysis
writingpublication
outreach
assessment discovery
Rounds of grant writing
and application
Iterations of
search and reading
Drafting, receiving
comments,rewriting
Submit, peer review,
rejection, resubmitting
Rounds of experiments
and measurements
7. A multi-cyclic, multi-ordered
model of the research workflow, with loops
preparation
analysis
writingpublication
outreach
assessment discovery
Rounds of grant writing
and application
Iterations of
search and reading
Drafting, receiving
comments,rewriting
Submit, peer review,
rejection, resubmitting
Rounds of experiments
and measurements
8. Three goals for science & scholarship (G-E-O)
• declaring competing interests
• replication & reproducibility
• meaningful assessment
• effective quality checks
• credit where it is due
• no fraud, plagiarism
• connected tools & platforms
• no publ. size restrictions
• null result publishing
• speed of publication
• (web)standards, IDs
• semantic discovery
• re-useability
• versioning
open peer review •
open (lab)notes •
plain language •
open drafting •
open access •
CC-0/BY •
good
efficient open
technical
changes &
standards
research
governance
changes
economic
& copyright
changes
researcher
funder
publisher
public
government library
22. Make these data work for you
Do Asian postdocs look more to impact
factors to select a journal to publish in than
their Latin American counterparts?
23. Make these data work for you
Is sharing ‘preprints’ gaining traction beyond
the fields of astronomy, physics and math, and
if so, what platforms are used?
24. Make these data work for you
Which tools are used in multiple research
phases, and are they leading tools
in any of these phases?