The document summarizes the overall pathways of glycolysis and the citric acid cycle/electron transport chain. Glycolysis occurs in the cytoplasm and involves glucose activation using 2 ATP and energy harvest from pyruvate production yielding 2 ATP and 2 NADH. The citric acid cycle and electron transport chain occur in the mitochondria, use oxygen, and produce 36 ATP and 2 carbon dioxide from the breakdown of 1 pyruvate, which is generated from glycolysis. Both pathways are exergonic overall.

1. B. GENERAL REACTIONS – overall pathway is exergonic
GLYCOLYSIS CITRIC ACID CYCLE & e-
TRANSPORT CHAIN
Where: Where:
cytoplasm mitochondrium
General: General
Does not use O2 Uses O2
Energy from substrate
Most ancient of pathways
Overall pathway: Overall pathway:
Glucose 2 pyruvate Pyruvate 6CO2 + 6H2O
net 2 ATP 36 ATP
2 NADH

2. III. SPECIFICS
A. GLYCOLYSIS – glucose activation and energy harvest
REACTION # CARBONS/ REACTION COMPOUND
NAME MOLECULE NAME & EXPLAIN
6 carbons (1 molecule) GLUCOSE
2 ATP
GLUCOSE
2 ADP
ACTIVATION +P
6 carbons (1 molecule) FRUCTOSE
BIPHOSPHATE
P P
ENERGY
HARVEST

3. III. SPECIFICS
A. GLYCOLYSIS – glucose activation and energy harvest
REACTION # CARBONS/ REACTION COMPOUND
NAME MOLECULE NAME & EXPLAIN
6 carbons (1 molecule) GLUCOSE
2 ATP
GLUCOSE 2 ADP
ACTIVATION +P
6 carbons (1 molecule) FRUCTOSE
BIPHOSPHATE
P P
3 carbons (2 molecules) G3P
2 ADP + 2P 2 ADP + 2P
2 ATP 2 ATP
ENERGY
HARVEST NAD + H NAD + H
NADH NADH
3 carbons (2 molecules) PYRUVATE

4. END PRODUCTS OF
GLYCOLYSIS
• 2 PYRUVATE MOLECULES – moves into mitochondrium matrix
• 2 NET ATP – Usually stays in cytoplasm to be used by the cell
2 used as activation energy (GLUCOSE ACTIVATION)
4 made when producing pyruvate (ENERGY HARVEST)
• 2 NADH – High energy compound that moves to e- transport chain.