Biologia molecular

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Biologia molecular

  1. 1. THE CYCLE CELL AND STRUCTURE DNA Laura Elena Cuartas Molecular Biology July 22/2012 UPB- Medellín
  2. 2. Telomeres andtelomerase serve to giveinformation about ageand pathologies likecancer.Cell division is a importantprocess to give rise to new cells containing their complete genomas.
  3. 3. Using biochemical andgenetic assays the proteinLem4 is structurally differentin human cells and embryosof the worm, but have thesame function in cell division.
  4. 4. Lem4 is a protein whichsimultaneously co-ordinatesthe activity of kinases andphosphatases on a targetprotein essential for celldivision.
  5. 5. It is essential that the nuclear envelope disappearsduring cell division and then reassemble it correctly, tooccur this is necessary for the participation of kinasesand phosphatases proteins.
  6. 6. Lem4 protein has a relation with the cancer patients
  7. 7. In this study we can observe the importance ofphosphorylation and desphosphorylation reactionsand its essential role in cell division and celloperation.
  8. 8. Telomerases protectchromosomes fromdeteriorating and guardthe genetic informationat the ends ofchromosomes duringcell division. Besides’they are consideredmarkers of biological orcellular aging.
  9. 9. Shortened telomeres have been linked to increased riskof cancers, heart disease, dementia and mortality.
  10. 10. The length oftelomeres dependson the stress,worries andphobias.
  11. 11. I think anxienty and stress are emotionalfeeling that people can control, becausethese affect cromosomes in the telomeresand reduce life average.
  12. 12. The DNA structure is very important because ithas the information about each personalgenome, this study has to protect the life and thepersonal safety and the culture of the peoplebecause al cientific investigation has to be ethics.
  13. 13. Knowledge of thenuclear envelopemet know differentmolecules involvedin cell cycle andthat way relatedpathologies such ascancer.
  14. 14. • MARTINEZ SANCHÉZ. LINA MARÍA. BIOLOGÍA MOLECULAR. 7. ED. MEDELLÍN: UPB. FAC. DE MEDICINA, 2012. 44-51 PAG.• Asencio C. Identified a essential protein in nuclear envelope assembly in cell division, according to the UPO.Europapresst [Internet journal] 2012 Jul [access 20 of July of 2012]. Available: http://www.europapress.es/andalucia/sevilla- 00357/noticia-identifican-proteina-esencial-ensamblaje- envoltura-nuclear-division-celular-upo-20120713150648.html• Okereke O. Anxiety linked to shortened telomeres, accelerated aging: research. Medicalxpress [Internet journal] 2012 Jul [access 20 of July of 2012]. Available: http://medicalxpress.com/news/2012-07-anxiety-linked- shortened-telomeres-aging.html

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