FFR is a technique used during coronary catheterization to measure pressure differences across a coronary artery stenosis to determine if it is restricting blood flow. FFR provides an invasive test to estimate the effects of a narrowed blood vessel in real-time without providing information on plaque morphology. Medications like adenosine are administered to increase the heart's workload and detect ischemia during FFR testing. Significant stenoses are considered less than 0.80 on the FFR scale while readings above 0.80 are not generally deemed significant obstructions.