This presentation gives a brief idea about angle of anterior chamber along with its structures and diagnostic methods to grade and visualize the structures.
This presentation gives a brief idea about angle of anterior chamber along with its structures and diagnostic methods to grade and visualize the structures.
A surgical procedure featuring a partial thickness scleral flap that creates a fistula between AC and subconjunctival space for filtration of aqueous and creation of conjunctival bleb in an effort to lower IOP
With a knowledge of anatomy, diseases of eyelids cannot be dealt with. Here we submit our presentation on anatomy of eyelids which will be helpful to all ophthalmogists, and students.
A surgical procedure featuring a partial thickness scleral flap that creates a fistula between AC and subconjunctival space for filtration of aqueous and creation of conjunctival bleb in an effort to lower IOP
With a knowledge of anatomy, diseases of eyelids cannot be dealt with. Here we submit our presentation on anatomy of eyelids which will be helpful to all ophthalmogists, and students.
www.ophthalclass.blogspot.com has the complete class and MCQs on lids and adnexa for undergraduate medical students. Class 1 in the series deals with the basic anatomy of the eyelid and the eyelid margin. A few of the congenital eyelid disorders are mentioned. Special emphasis is given to blepharitis – inflammation of the eyelid margin, its types, clinical features and management. Next, common causes of eyelid swellings including hordeolum or stye and chalazion are discussed. Finally a brief mention is made about disorders of the eyelashes – trichiasis, poliosis, madarosis and distichiasis.
www.ophthalclass.blogspot.com has the complete class and MCQs on lids and adnexa for undergraduate medical students. The third class in this series deals with blepheroptosis. The subtopics include diagnosis of ptosis, pseudoptosis, classification of ptosis into congenital and acquired ptosis and finally a brief discussion on the management of ptosis. Clinical features of congenital myogenic ptosis, Marcus jaw winking phenomenon, aponeurotic ptosis, neurogenic ptosis (III nerve palsy and Horner’s syndrome), CPEO, myasthenia gravis, traumatic and mechanical ptosis are explained.
This lecture includes anatomy, Physiology of eyelids, if u like it kindly share it with colleagues and like it. I will share more lectures related to eye anatomy and optometry.
Thank You.
Each eyelid contains a fibrous plate, called a tarsus, that gives it structure and shape; muscles, which move the eyelids; and meibomian (or tarsal) glands, which secrete lubricating fluids. The lids are covered with skin, lined with mucous membrane, and bordered with a fringe of hairs, the eyelashes.
This is an educational presentation on contents of orbit. The presentation includes anatomy of bony orbit, eyelids, conjunctiva, lacrimal glands and extra ocular muscles with their action explained in detail.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
2. EYELID ANATOMY
Embryology:-
Eyelids- reduplication of surface ectoderm above & below cornea
during 2nd month of IUL.
Folds enlarge & their margins meet & fuse with each other to enclose a
space - conjunctival sac.
Folds thus formed contain some mesoderm which gives muscles of
eyelid & tarsal plates.
Lids seperates after 7th mon of IUL.
Tarsal glands developes from ingrowth of solid columns of ectodermal
cells from the lid margins.
Ciliary glands are outgrowths
from ciliary follicles.
Cilia developes as epithelial buds from lid margines.
2
3. Gross anatomy:-
• Eyelids are mobile tissues curtains placed in front of the
eyeballs.
• Extent:-upper lid extends form eyebrows above to free lid
margins bellow & lower lid merges bellow into skin of cheek.
• Lid folds:-
A. Superior lid fold - 4mm above lid margins
-formed by fibrous slip arrising from levator tendon
-divides upper lid into orbital and tarsal parts
B. Inferior lid fold – formed by fibrous slip arising from fascia
around IR
C. Nasojugular (medial) fold Both marks the line betn skin &
D. Malar (lateral) fold denser tissue of cheek –limits the .
spread blood downwards from
. lid to cheek.
2
4. • Position- in primary gaze upper lid covers 1/6 of cornea & lower
lid just touches cornea.
• Canthi -
Lateral canthus -5-7mm from lateral orbital margines
-forms 30-40 degree when eyes are normally open
Madial canthus- seperated from globe by tear lake (lacus
lacrimalis).
3
5. • Lid margins – 2 mm in width
-divided by lacrimal papilla into
Medial portion Lateral portion
(lacrimal portion) (Cilliary portion )
-devoid of lashes & -rounded anterior & sharp post
glands border
-Intermarginal strip- divided by grey line into
Anterior strip posterior strip
-bears eye lashes -bears opening of mebomian glands &
lipid strip.
• Eye lashes-2-3 rows
UL - (100-150) directed forward ,upward & backward
LL – (50-75) directed forward , downward & backward
4
6. • Cilia-
20-129 µm in diameter.
6-12mm in length.
lifespan 3-4 months shed off goes in dormant phase or
weeks new hair grows.
Lacks errector muscles
Glands off Zies & Moll empties into infundibulum of these cilia.
• Palpabral apperture /fissure-
Elliptical space betn upper & lower lid margins
1
At birth In adults
At birth In adults
In caucation race fissure is either horizontal or lateral
canthus is slightly <2mm higher than medial canthus..
18-20mm
8mm
28-30mm
9-11mm
5
7. Mongoloid slant Lateral canthus is >2mm higher than medial.
Antimongoloid slant Lateral canthus is lower than medial.
Structure :-
i. Skin
ii. Subcutaneus areolar tissue (pic)
iii. Layer of striated muscle
iv. Submuscular areolar tissue
v. Fibrous layer
vi. Layer of non striated muscle
vii. conjunctiva
6
8. i. Skin :- Elastic & folds easily
Thinnest in body
Epidermis *is stratified squamous epithelium 6-7
layered,
* Basal layer contain numerous unicellular
sebacious glands & typical eccrine sweat glands..
* At margins , get modified & continues with
conjunctiva.
Dermis *Rich network of elastic fibers, blood
vessels, nerves, lymphatics with variable no. of
MELANOCYTES * es their production in
response chronic edema or inflamation.
ii. Subcutaneous areolar tissue :-
Loose connective tissue
Contains no fat
*Radially distended by blood or fluids .
**easily mobilized during plastic sx .
7
9. iii. Layer of striated muscle:- 2 muscles orbicullaries oculi & levator
1.Orbicularis oculi palpabrae
Orbital part (peripheral) Palpebral part
Origin- Ant part of MPL &
adj bone fibers sweep
superiorly & inferiorly to a . Preseptal part b.Pretarsal part
meet at lateral palpebral raphe.
Musculus Supercilliaries – Origin- both parts originates through
Upper Medial fibers of orbital superficial head (MPL) & deep head
part which passes to skin of (Lacrimal fascia & crest)
eyebrow. Fibers then sweep superiorly & inferiorly
Musulus malaries-Inferiorly to meet laterally to form Lateral canthal
medial& lateral fibers attached tendon inserted over lat orbital tubercle
to skin of cheek of whitnall
*causes forceful closure of *causes gentle clossing of eyelid
eyelid during blinking & sleeping.
8
11. Horner’s muscle (pars lacrimalis) - Fibers of pretarsal portion arising from
lacrimal fascia & upper part of post lacrimal crest .
*helps in draining tears by lacrimal sac
Muscle of Riolan (pars ciliaries) – Fibers of pretarsal portion which run along
lid margins behind ciliary follicles
*keeps lid in close opposition to globe.
Nerve supply:- facial nerve
2.Levator palpabrae superioris..
Origin:- at appex of orbit from under
surface of lesser wing of sphinoid above
annulus of zinn.
10
12. Course:-
Fleshy part - Horizontal , approx. 40mm
passes forward & nasally , below
roof of orbit & above SR muscle.
Tendinous part – Vertical , 15mm long &
30 mm wide. Forms an
aponeurosis occupying whole lid.
Madial horn – fuses with medial canthal tendon
Lateral horn – is thicker & divides lacrimal
gland into orbital &
palpebral part.
Insertion:- on superior edge of lateral canthal tendon, anterior
surface & upper border of tarsus & some fibers to skin &
sup conjunctival fornix.
Nerve supply :- superior division of occulomotor nerve.
Action:- Elevator of lid (its action is antagonised by palpabral part
of orbicularis oculi)
11
13. Superior transverse ligament of Whitnall
Thickened band of orbital fascia
which extends trochlear pulley (PIc)
(medially) to capsule of orbital lobe
of lacrimal gland (laterally).
It’s a condensation of fibers of SR & LPS .
*Recognition of ligament during
ptosis sx is imp as severing of lig
can leads to failure of LPS function.
iv. Submuscular areolar tissue:-
Its tissue betn orbicularis oculi & fibrous layer.
contains nerves & vessels of lid.
*to anaesthetize the lid injection is made in this plane.
**in upper lid, this layer communicates with dangerous area of
scalp giving way to extravasseted blood & pus.
12
14. Spaces:-
a. Pretarsal space- bounded ant- Levator aponeurosis & post – tarsal
plate. Fusiform in vertical section. Contains arterial
arcade.
b. Preseptal space- bounded ant – orbicularis oculi , post – septum
orbitale & above by preseptal fat cushion..
a.Tarsal plate
v. Fibrous layer:- b.Septum orbitale
c. Medial palpebral lig.
d.Lateral palpebral lig.
a.Tarsal plate-
• Plates of dense fibrous tissue.
• Size – 29 mm long , 1mm thick, ht – upper 10-11mm & lower 4-5mm.
13
15. 14
Parts Attachments
Sup border of upper tarsus Septum orbitale ,
Muller’s muscle
Inf border of lower tarsus Septum orbitale,
Capsulopalpebral fascia,
Inferior palpebral muscle
Ant surface of upper tarsus Levator aponeurosis
Post surface of both Conjunctiva
Lateral ends Whitnall’s tubercle by LPL
Medial end Ant lacrimal crest & frontal process of
maxilla by MPL.
Containts Mebomian glands.
16. b. Septum orbitale( palpebral fascia):-
Thin floating membrane of connec-
tive tissue.
Attachments peripherally to
orbital margins at thickening
called arcus marginale. & centrally to
convex borders of tarsal plates.
Relations:-
Ant-Orbicularis oculi , LPS
Post- Orbital fat , LPS, SO tendon
*On the upper medial angle ,There is tendency for fat to Herniate
through gap left by non attachment of septum to orbital margin
15
17. Structures piercing :-
• Lacrimal nerves & vessels
• Supraorbital nerves & vessels
• Supratrochlear artery & nerve
• Infratrochlear nerve
• Anastomosing vein betn angular
& ophthalmic vein.
• Sup & Inf palpebral arteries
• Aponeurosis of LPS
• Expansion of LR
c. Medial palpabral lig – Triangular in shape.
Has anterior part-Attached to ant lacrimal crest & fans out laterally.
Angular artery & vein passes over medial part of ant surface..
Posterior part – passes behind lacrimal sac from ant to post lacrimal
crest..
16
18. d.Lateral palpabral lig.- about 7 mm in length &2.5 mm in ht.
Attachments- laterally-whitnall’s tubercle
medially –lateral ends of tarsal plates
Relations - Ant surface- Lateral palpebral raphe
Post surface-check lig of lateral rectus.
Upper border – merges with aponeurosis of LPS
Lower border – merges with expansions of IO &
IR
vi. Layer of non striated muscle fibers:-
Contains Muller muscle k/a Sup & Inf palpebral muscles.
Origin:- terminal fibers of LPS in upper lid & IR in lower lid.
Insetion:- orbital parts of tarsal plates.
Nerve supply:- Sympathetic nerves
Action:- Retraction of lids
*paralysis leads to Horner syndrome.
vii. Conjunctiva.
17
19. Glands of eyelid
Mebomian Zeis Moll Krause & wolfring
*modified sweat *modified seba *modified sweat *accessory lacrimal
Glands ceous glands glands glands
*+nt in sroma of *opens in eye *lie betn cilia *+nt along superior
tarsal plates lash follicle *numerous in border of upper
*20-30 in each lid *secretes sebum LL tarsus & inf border
*opens at post *prevents eye *r unbranched of lower tarsus
Part of intermarg- lashes to beco- spiral shape *2-5 in upper lid
Inal strip me dry & 2-3 in lower lid.
*Secretes sebum *contributes to
lipid layer of
tear film. Cont…..
18
20. Mebomian glands:-
Functions:-
-Oily marginal tear strips prevent the
overflow of tears across lid margins.
-Oily layer of tear film prevents
evaporation of tears & allows free
movement of lid over globe.
-Ensures the airtight closure of eyelids
19
21. • Arterial supply-
-Medial & lateral palpebral arteries
Br.of Dorsal nasal & Lacrimal artery
-Each medial artery anastomose
with Lateral artery to form
marginal arterial arcade.
• Venous drainage:- through 2 plexuses
i. Pretarsal plexus-drains structures superficial to tarsus.
medial side drains into angular vein Int jugular vein.
lateral side drains into superficial temporal & lacrimal vein
Exrtnal jugular vein.
ii. Posttarsal plexus- drains structures posterior to tarsus.
drains into Ophthalmic vein.
20
22. • lymphatic drainage:
• Medial group Lateral group
Superficial trunk Deep trunk Superficial trunk Deep trunk
*Drains-
Structures of conjunctiva of Structure of
Medial ½ of LL medial 2/3 of LL Lateral ¾ of UL UL & conjunctiva
Medial ¼ of UL & caruncle Lateral part of LL of lateral 1/3 of LL
Medial cummisure
Superficial Deep Superficial parotid & Deep parotid
submandibular LN submandibular LN preauricular LN LN
21
23. • Nerve supply:-
Motor supply –facial nerve (orbicularis), oculomotor N. (LPS)
Sensory –Trigeminal nerve
upper lidsupraorbital , supratrochlear, infra trochlear & lacrimal
lower lidinfraorbital , infratrochlear & lacrimal.
Sympathetic supply to muller’s muscle, skin & glands.
22
24. Congenital anomalies of eyelid
A. Eyelid coloboma:-
-eyelid defect due to either due to failure of migration of lid
ectoderm to fuse the lid folds or mechanical forces such as
amniotic band.
*Upper lid coloboma-
Middle & inner 1/3
Associated with criptophthalmos,
Facial anamolies & Goldenhar syndrome.
i.e (Oculo-auriculo-vertebral syndrome)
*Lower lid coloboma-
N At junction of Outer & middle 1/3
23
25. *Treacher collins syndrome –(mandibulofacial dysostosis)-
Malformation of derivatives of 1st & 2nd brachial arch…
B. Cryptophthalmos:-
-Eyelids absent
- Freaser syndrome: Syndactyly,
urogenatal & craniofacial abnormalities.
C. Euryblepharon:-
-Horizontal enlargement of palpabral fissure
+ lateral canthus ectropion
24
26. D. Microphthalmos:-
-small eyelids , sometimes
associated with anophthalmos
E. Ablepharon:-
-deficiency of anterior lamellae of eyelid
25
27. F. Ankyloblepharon:-
-upper & lowerlids are joined by thin tags..
G. Epicanthic folds:-
- Bilateral vertical folds of skin that extend
from upper & lower lids towards the medial canthus.
- pseudoexotropia
26
28. H. Telecanthus:-
-Increased distance between the medial
canthi d/t abnormally long medial canthal
Tendon
- In contrast hypertelorism is wide bony
separation of orbits.
27
30. Tear film –
• Consist of 3 layers-
i. Superficial lipid layer secreted by mebomian glands
ii. Middle layer of aqueous secreted by accessory lacrimal
glands & minimally by main lacrimal gland.
iii. Deeper layer of mucus secreted by goblet in conjunctiva..
29
32. Tear film dynamics
Main role of lacrimal passage is to
establishe & maintain a contineous tear film over
preocular surface. Tear film dynamics include,
i. Secretion of tear film
ii. Formation of tear film
iii. Retaintion & redistribution of tear film
iv. Displacement phenomenon
v. Evaporation of tear film
vi. Drying & breakup of tear film
vii.Dynamic events during blinking
viii.Elimination of tears.
31
33. i. Secretion of tear film
Tears are continuously secreted by
-Main lacrimal galnd (Reflex secetion) responsible for
hypersecretion.
-Acceessory lacrimal gland(basal secretion)secondary to light or
temp stimulation through propreoceptors
Supplied by afferent pathway through Trigeminal nerve &
efferent through parasympathetic .
Normal tear production @ about 1.2 µl/min , of volume approx.
7 µl, turnover rate 5-7 min .
* newborn babies secrete tears within 24 hrs but abnormal tearing
(hyper lacrimation) starts after the age of 4 mon.
32
34. ii. Formation of tear film
Wettability of surface depends on angle Ø .
If angle θ=90 degree –surface is hydrophobic
If angle θ < 90 degree - surface is relatively hydrophobic
If angle θ = 0 degree – surface is hydrophilic
Corneal epithelium is relatively hydrophobic.
*During blinking lids spread conjunctival mucus over cornea &
converts it into hydrophilic surface
*On this aqueous layer spreads spontaneously.
*F/b lipid layer spreads contributing to its stability & reducing
evaporation .
33
35. iii. Retention & redistribution of film
Tear film is retained at uniform thickness over corneal surface
against gravitational force due to outermost layer of corneal
epithelium long with mucopolysaccharide layer.
Redistribution occures in the form of bringing new tear fluid by
the way of marginal strip where there is constant flow of tears.
iv . Displacement phenomenon
When lower lid is displaced upward over the eye ball there occurs
displacement of monomolecular layer of tear film..
This phenomenon is attributed to Stability , compressibility &
elasticity of tear film.
34
36. v. Evaporation of tear film
Evaporation is decreased by superficial lipid layer, specially
in arid &windy climate.
Rate of evaporation estimated to be 10% of production rate.
i.e approx. 0.12μl/min.
vi. Stability ,drying & rupture of tear film.
Tears can function properly only if it covers preocular surface &
redistributed quickly & completely after blink..
.When blinkiny is prevented for 15-40 secs , tear film ruptures
& dry spot appers..
35
37. Holly & Lemp’s mechanism-
Tear film thins uniformly by evaporation
To some critical level , significant no of lipid
molecules begin atracting towards mucin layer
when mucin layer is sufficiently coated contaminated
by lipid migrating down to mucin layer.
it becomes hydrophobic
Tear film ruptures. Dry spot formation occurs
*twice more common temporally than nasally bcz nasal areas
are more protected against air current
.
36
39. vii. Dynamic events during blinking
As upper lid moves downwards , superficial layer is
compressed.
Whole of lipid layer together with associated biopolymers gets
compressed betn lid edges.
When eyelid opens ,first the monomolecular lipid layer spreads
followed by multi molecular layer of lipids formed.
Thus removing the lipid contaminants from mucus layer &
removing the breaks.
Drainage of lacrimal fluid from lacus lacrimalis into
nasolacrimal duct. 20% -upper punctum
80%-lower punctum.
Lacrimal fluid from preocular surface reaches marginal strip
tears collects at Lacrimal lake in medial canthus lacrimal
canaliculi lacrimal sac NLD Inferior meatus
37
40. Horner’s muscle constitute lacrimal pump.
Fibers of preseptal portion of orbicularis oculi that arises from
post lacrimal crest & lacrimal fascia.
A) Events occurring during closure of eyelid:-
i. Contraction of pretarsal fibers compresses ampulla &
shorten lacrimal canaliculi Propels tears from ampulla &
canaliculi towards sac
ii. Contraction of preseptal fibers pulls lacrimal fascia &
lateral wall of lacrimal sac laterally creates –ve pressure in
sac & opens sac draws fluid from canaliculi to sac
iii. Increased tension along lacrimal fascia inferior end of NLD
closes
38
42. B) Events occurring during closure of lid:-
i. Relaxation of pretarsal fibers of orbicularis allows
canaliculi to open & expand draws tears from
lacrimal lake to canaliculi.
ii. Relaxation of preseptal fibers (Horner’s muscle)
causes lacrimal sac to collapse Expels fluid
downwards to open in meatus.
40
44. Drainage of lacrimal fluid by NLD.
• Gravity
• Air current movement in nose- induces –ve pressure in
nose
• Hasner’s valve – Mucus membrane fold forming a valve
at lower end of NLD.
-remains open as long as pressure within nose is less
than NLD & allows tears to drain into nose.
- when intranasal pressure increase as in Blowing the
nose , Hasner’s valve closes there by preventing the
reflux upward.
42