The human excretory system is responsible for removing waste, consisting of organs such as the liver, lungs, large intestine, skin, and the urinary system including kidneys. The kidneys filter blood, form urine, and maintain water and electrolyte balance, while the ureters, bladder, and urethra facilitate urine transport and storage. Key terms related to the excretory system include renal failure, which signifies inadequate kidney function in filtering waste.