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Drug containing lipids
and volatile oils
SUBMITTED BY
T . SOUNDARYA
III B.SC BIO CHEMISTRY
16BC527
INTRODUCTION
Pharmacology is the study of the biological
effects that the chemicals in medical plants
have on cell cultures, animal and human
practical perspectives as follows quality
control efficacy, safety.
DRUG CONTAINING LIPIDS
 Lipids are water insoluble, oily organic compounds
soluble in non polar organic solvents.
 The fixed oils and fats are separated from crude
vegetable drugs or crude animal drugs and are used as
drugs in refined state.
 Fatty oils are the resources of food materials of plants
(arachis oil, sesame oil, castor oil, rice bran oil, cocoa
butter, neem oil )
CASTOR OIL
Biological Sources :
 Castor oil is a semi drying fixed oil extracted from the
seeds of “ RICINUS COMMUNIS LINN ”
 The common names of the product are ricinus oil,
eleum ricins, oil of palma Christ, aamanakku oil
villakkennai.
COLLECTION AND PREPARTION OF OIL
 Mature Seeds are collected, graded, cleaned, washed
and sun dried.
CHARATERISTICS OF OIL
 COLOR : pale yellow and brown colored powder or almost colorless liquid.
 ODOUR : Slight and Characteristics.
 TASTE : First is bland but afterwards slightly acid and usually nauseating.
 APPEARANCE : Transparent and viscous liquid.
 KEEPING QUALITY :
 STANDARDS :
* Weight per ML : 0.945 to 0965g
* Acid : Note more than 2
* Iodine : 81 to 90
* : 6.8 poises
* Specific gravity : 0958 to 0.969
* Refractive Index : 1.467 to 1.479
* A Value : about 150
* Solidifying point : -10* to -18*c
CHEMCIAL CONSTITUENTS
CASTOR OIL MIXTURE OF FIXED OIL 45-55%
 Proteins 20%
 Ricinoleic acid 87%
 Isoricininoleic 2%
 Stearic 1%
 Oleic 7%
 Palmitic acid 2%
USES
 Castor oil puragative and emolliend and is used for lubrication
commercialy
 It is used for external application
 Ointment base
 In case of food poisoning the use of castor oil in hospitals
 Surfactants, cosmetics, paints, varnishes, grease, polishes,
printing in.
 Used in contraptive creams and jellies
 It is the chief raw material for the production of sebacic acid
NEEM OIL
 BIOLOGICAL SOURCE :
It is an non edible fixed oil obtained from fully mature seeds
of AXADIRACHTA INDICA MELIN…
 DESCRIPTION :
It is yellow colored oil with specific color and bitter taste.
It is soluble in ether and chloroform
 CHEMICAL CONSTITUENTS :
Oleic acid ( 50 % ) & Stearic acid ( 20 % )
Oil contains 2% of bitters, which are sulphur containing
compounds, nimbidin , nimbinim and nimbidol
The unsaponifiable part contains nimbo sterol ( 0.03% )
USES
 Anti viral activity
 As an non edible oil, it is used for soap making and for
manufacturing of oleic and stearic acids
 It is indicated in rheumatism and also as a pesticide and
in medicated soaps for skin diseases.
 It is also spermicidal
DRUGS CONTAINING VOLTILE OILS
 The volatile principles of plan and animal sources that
are odoriferous, constitute volatile oils when exposed
to air at room temperature, they evaporate. Hence they
are called “ ethereal oils ”. As they represents essence
or active constituent of a plant, they are known as “
essential oils ”
 Volatile oils are extensively used as flavouring and
perfuming agents in pharmaceuticals, food, beverages
and cosmetics.
TURPENTINE OIL
 BIOLOGICAL SOURCE : Turpentine oil is the volatile oil
distilled from oleoresin obtained from pinus palustris,
p.rorburghi, p.maritima species of the genus pinus of
the family pinaceae.
 GEOGRAPHICAL DISTURBUTION : Pinus is a perennial
tree turpentine oil is commercially produced in India
 PREPARATION : “ bark – hack ”
CHARACTERISTICES OF TURPENTINE OIL
 COLOUR : clear, colorless, slightly yellow
 ODOUR : strong & characteristic odour
 TASTE : pungent and bitter
 SOLUBILITY : in soluble in water, soluble in alcohol
STANDARD
 Weight per ml - 0.864 to 0.868g
 Refractive index – 1.467 to 1.477
CHEMCIAL CONSTITUENTS :
 Turpentine oil rich in tarpene and about 40 terpene
 It mainly contains α – pinene ( 20 to 30% )
 β – pinene ( 5 to 10 % ) δ – 3 canine, limonene
 Camphene , β – phellandrene
USES :
 Turpentine oil is chiefly used as an effective counter – irritant and rubefacient
in the form of liniments to be used externally
 It has antiseptic and disinfectant properties
 It is used in the manufactures of synthetic palm oil, insecticides, pints and
varnish
 It is used in the treatment of chronic bronchitis
STORAGE
 Turpentine oil should be stored in a cool place in amber
– coloured , well – closed containers and kept away
from light.
 Don’t eat junk food
 Eat healthy live healthy
THANK
YOU

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Drug containing lipids and volatile oils ss

  • 1. Drug containing lipids and volatile oils SUBMITTED BY T . SOUNDARYA III B.SC BIO CHEMISTRY 16BC527
  • 2. INTRODUCTION Pharmacology is the study of the biological effects that the chemicals in medical plants have on cell cultures, animal and human practical perspectives as follows quality control efficacy, safety.
  • 3. DRUG CONTAINING LIPIDS  Lipids are water insoluble, oily organic compounds soluble in non polar organic solvents.  The fixed oils and fats are separated from crude vegetable drugs or crude animal drugs and are used as drugs in refined state.  Fatty oils are the resources of food materials of plants (arachis oil, sesame oil, castor oil, rice bran oil, cocoa butter, neem oil )
  • 4. CASTOR OIL Biological Sources :  Castor oil is a semi drying fixed oil extracted from the seeds of “ RICINUS COMMUNIS LINN ”  The common names of the product are ricinus oil, eleum ricins, oil of palma Christ, aamanakku oil villakkennai.
  • 5. COLLECTION AND PREPARTION OF OIL  Mature Seeds are collected, graded, cleaned, washed and sun dried.
  • 6. CHARATERISTICS OF OIL  COLOR : pale yellow and brown colored powder or almost colorless liquid.  ODOUR : Slight and Characteristics.  TASTE : First is bland but afterwards slightly acid and usually nauseating.  APPEARANCE : Transparent and viscous liquid.  KEEPING QUALITY :  STANDARDS : * Weight per ML : 0.945 to 0965g * Acid : Note more than 2 * Iodine : 81 to 90 * : 6.8 poises * Specific gravity : 0958 to 0.969 * Refractive Index : 1.467 to 1.479 * A Value : about 150 * Solidifying point : -10* to -18*c
  • 7. CHEMCIAL CONSTITUENTS CASTOR OIL MIXTURE OF FIXED OIL 45-55%  Proteins 20%  Ricinoleic acid 87%  Isoricininoleic 2%  Stearic 1%  Oleic 7%  Palmitic acid 2%
  • 8. USES  Castor oil puragative and emolliend and is used for lubrication commercialy  It is used for external application  Ointment base  In case of food poisoning the use of castor oil in hospitals  Surfactants, cosmetics, paints, varnishes, grease, polishes, printing in.  Used in contraptive creams and jellies  It is the chief raw material for the production of sebacic acid
  • 9. NEEM OIL  BIOLOGICAL SOURCE : It is an non edible fixed oil obtained from fully mature seeds of AXADIRACHTA INDICA MELIN…  DESCRIPTION : It is yellow colored oil with specific color and bitter taste. It is soluble in ether and chloroform  CHEMICAL CONSTITUENTS : Oleic acid ( 50 % ) & Stearic acid ( 20 % ) Oil contains 2% of bitters, which are sulphur containing compounds, nimbidin , nimbinim and nimbidol The unsaponifiable part contains nimbo sterol ( 0.03% )
  • 10. USES  Anti viral activity  As an non edible oil, it is used for soap making and for manufacturing of oleic and stearic acids  It is indicated in rheumatism and also as a pesticide and in medicated soaps for skin diseases.  It is also spermicidal
  • 11. DRUGS CONTAINING VOLTILE OILS  The volatile principles of plan and animal sources that are odoriferous, constitute volatile oils when exposed to air at room temperature, they evaporate. Hence they are called “ ethereal oils ”. As they represents essence or active constituent of a plant, they are known as “ essential oils ”  Volatile oils are extensively used as flavouring and perfuming agents in pharmaceuticals, food, beverages and cosmetics.
  • 12. TURPENTINE OIL  BIOLOGICAL SOURCE : Turpentine oil is the volatile oil distilled from oleoresin obtained from pinus palustris, p.rorburghi, p.maritima species of the genus pinus of the family pinaceae.  GEOGRAPHICAL DISTURBUTION : Pinus is a perennial tree turpentine oil is commercially produced in India  PREPARATION : “ bark – hack ”
  • 13. CHARACTERISTICES OF TURPENTINE OIL  COLOUR : clear, colorless, slightly yellow  ODOUR : strong & characteristic odour  TASTE : pungent and bitter  SOLUBILITY : in soluble in water, soluble in alcohol STANDARD  Weight per ml - 0.864 to 0.868g  Refractive index – 1.467 to 1.477
  • 14. CHEMCIAL CONSTITUENTS :  Turpentine oil rich in tarpene and about 40 terpene  It mainly contains α – pinene ( 20 to 30% )  β – pinene ( 5 to 10 % ) δ – 3 canine, limonene  Camphene , β – phellandrene USES :  Turpentine oil is chiefly used as an effective counter – irritant and rubefacient in the form of liniments to be used externally  It has antiseptic and disinfectant properties  It is used in the manufactures of synthetic palm oil, insecticides, pints and varnish  It is used in the treatment of chronic bronchitis
  • 15. STORAGE  Turpentine oil should be stored in a cool place in amber – coloured , well – closed containers and kept away from light.
  • 16.  Don’t eat junk food  Eat healthy live healthy THANK YOU