small presentation on different types of bioreactor

1. DIFFERENT TYPES OF
BIOREACTER
PREPARED BY: SHIVAM PATEL
SUBJECT: BIOPROCESS ENGINEERING
ENROLLMENT NO.:14BT001830

2. Stirred Tank Bioreactor
• In this bioreactor air is dispersed by mechanical
agitation. Temperature, pH, amount of dissolved
oxygen and nutrient concentration can be
controlled better with this reactor compared to other
reactors.
• Impeller speed is reduced to 50-150 rpm

5. Air lift bioreactor
• Compressed air is used for aeration and mixing of the
contents.
• This is one of the most suitable bioreactor types for
cultivation of plant cells on a large scale.
Merits:
• It provides reasonable mixing and oxygen transfer at low
shear.
• As it has no moving parts, it has less contamination
problem.
• Operating cost is lower than stirred tank reactor.
Demerit:
• Develop dead zones, due to insufficient mixing at high cell
density

7. Bubble column bioreactor
• This is one of the simplest bioreactor. It consists of a
cylindrical vessel aerated at the bottom.
• Provide high mass and heat transfer areas without
the input of mechanical energy.
• Require minimum maintenance.

8. Fluidized Bed Bioreactors
• Fluidized bed bioreactor is comparable to bubble
column bioreactor except the top position is
expanded to reduce the velocity of the fluid.
• The design of the fluidized bioreactors (expanded top
and narrow reaction column) is such that the solids
are retained in the reactor while the liquid flows out.
• These bioreactors are suitable for use to carry out
reactions involving fluid suspended biocatalysts such
as immobilized enzymes, immobilized cells, and
microbial flocs.

10. •Advantages:
1. Uniform particle
mixing.
2. Uniform
temperature
gradient.
3. Ability to operate
reactor in
continuous state.
•Dis-advantages:
1. Increased reactor
vessel size.
2. Pumping
requirement.
3. Pressure drop.