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b.stev Describe: Immune Defence - Humans
NON-specific immune response, description: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
COMPLEMENT SYSTEM ,[object Object],[object Object],[object Object],[object Object],the 2 MAIN pathways of the COMPLEMENT SYSTEM starter proteins:  attach to invasive microbe -  gives recognition of  it’s presence -  the complement system responds
2. CLASSICAL: group of  proteins  in the blood that triggers a specific antibody response to the pathogen 1. ALTERNATE:  specific  proteins   bind in sequence   to pathogen   -  initiates  c a s c a d e of response  enzymes secreted -  enzymes   attack pathogen’s cell membrane , (opens)  DEATH results called:  MEMBRANE ATTACK COMPLEX one  of the  most   useful   weapons  to the  body (Wikipedia, 2008)
INTERFERON   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],certain  glycoprotein  – known as, CYTOKINE is secreted produced : immune cells after foreign encounter (mostly) CYTOKINE(S): communicate a pathway by signalling a response from specific immune cells, throughout the various stages of the process, ie: -  upgrade gene production, classical complement system -  downgrade response, via the use of feedback inhibition
PHAGOCYTES:  (engulf unwanted matter)  dispose of toxins, tired cells & dead foreign bodies  PUS:  (debris) accumulated from the immune response INFLAMMATORY RESPONSE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],PAIN  felt - expanded tissues continually trigger nerves that signal,  pressure : sensitivity results
[object Object],[object Object],[object Object],[object Object],[object Object],FEVER ,[object Object],[object Object],[object Object],[object Object],[object Object],produce: unfavourable environment to the pathogen ie: some microbes  only  tolerate  specific temperatures &  disturbance (s) within their HOST ENVIRONMENT this response favours the bodies needs: (Wikipedia, 2008)
PLASTER: (band-aid) covers wound PHYSICAL BARRIERS HAIR :   surface area over the skin (sense) SKIN :  contains the physical body within repair/ renewal – maintains barrier NAILS :  protects appendage ends - wounds/ bruising CLOTHES PROTECTIVE GEAR: masks/ gloves/ suit/ shoes QUARANTINE ENVIRONMENTS BUILDINGS
CHEMICAL INHIBITORS stomach acid:  pH 2 – unfavourable to most bacteria mucus:  traps microbes & debris mucus linings:  cilia :  move particle(s) out for excretion via  - outward direction sebum:  pH 5.5 – inhibits microbial growth bile:  secreted by gallbladder to the duodenum enzyme:  tears/ sweat/ saliva contain,  lysozyme - disrupts cell wall (digests peptidoglycan)
MICROBIAL COMPETITION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],(Wikipedia, 2008)
Bibliography Kennedy. A. (1999).  The  inflammatory response . Retrieved October 18,  2008, from  http//: www.alan.kennedy.name/crohns/primer/inflresp . htm - 11k - Wikipedia. (2008).  Complement system - wikipedia,the free encyclopedia . Retrieved October 17, 2008, from  http//:www. en.wikipedia. org/wiki/ Complement _system - 66k -  Wikipedia. (2008).  Interferon - wikipedia,the free encyclopedia . Retrieved October 17, 2008, from  http//:www. en.wikipedia. org/wiki/ Interferon  - 111k - Wikipedia. (2008).  Inflammation - wikipedia,the free encyclopedia . Retrieved October 17, 2008, from  http//:www. en.wikipedia. org/wiki/Inflammation - 130k -
Wikipedia. (2008).  Fever - wikipedia,the free encyclopedia . Retrieved October 17, 2008, from  http//:www. en.wikipedia. org/wiki/ Fever  - 77k -   Pommerville J.C. (2004).  Alcamo’s – Fundamentals of Microbiology   (7 th  ed.). Massachusetts: Jones and Bartlett.

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Describe Defence Mechanisms - Humans

  • 1. b.stev Describe: Immune Defence - Humans
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  • 4. 2. CLASSICAL: group of proteins in the blood that triggers a specific antibody response to the pathogen 1. ALTERNATE: specific proteins bind in sequence to pathogen - initiates c a s c a d e of response enzymes secreted - enzymes attack pathogen’s cell membrane , (opens) DEATH results called: MEMBRANE ATTACK COMPLEX one of the most useful weapons to the body (Wikipedia, 2008)
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  • 8. PLASTER: (band-aid) covers wound PHYSICAL BARRIERS HAIR : surface area over the skin (sense) SKIN : contains the physical body within repair/ renewal – maintains barrier NAILS : protects appendage ends - wounds/ bruising CLOTHES PROTECTIVE GEAR: masks/ gloves/ suit/ shoes QUARANTINE ENVIRONMENTS BUILDINGS
  • 9. CHEMICAL INHIBITORS stomach acid: pH 2 – unfavourable to most bacteria mucus: traps microbes & debris mucus linings: cilia : move particle(s) out for excretion via - outward direction sebum: pH 5.5 – inhibits microbial growth bile: secreted by gallbladder to the duodenum enzyme: tears/ sweat/ saliva contain, lysozyme - disrupts cell wall (digests peptidoglycan)
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  • 11. Bibliography Kennedy. A. (1999). The inflammatory response . Retrieved October 18, 2008, from http//: www.alan.kennedy.name/crohns/primer/inflresp . htm - 11k - Wikipedia. (2008). Complement system - wikipedia,the free encyclopedia . Retrieved October 17, 2008, from http//:www. en.wikipedia. org/wiki/ Complement _system - 66k - Wikipedia. (2008). Interferon - wikipedia,the free encyclopedia . Retrieved October 17, 2008, from http//:www. en.wikipedia. org/wiki/ Interferon - 111k - Wikipedia. (2008). Inflammation - wikipedia,the free encyclopedia . Retrieved October 17, 2008, from http//:www. en.wikipedia. org/wiki/Inflammation - 130k -
  • 12. Wikipedia. (2008). Fever - wikipedia,the free encyclopedia . Retrieved October 17, 2008, from http//:www. en.wikipedia. org/wiki/ Fever - 77k - Pommerville J.C. (2004). Alcamo’s – Fundamentals of Microbiology (7 th ed.). Massachusetts: Jones and Bartlett.