Cryotherapy refers to the use of local or general body cooling for therapeutic purposes. It is commonly used to treat acute trauma and subacute injuries. The magnitude of cooling and heat loss from tissues depends on factors like the temperature difference between the coolant and tissue, duration of exposure, thermal conductivity of tissues, and size of area cooled. Common cryotherapy methods include ice massage, ice towels, immersion in cold water or cold whirlpools, ice packs, and vapocoolant sprays. Cryotherapy provides benefits like pain relief through vasoconstriction and reduced metabolic rate, reduced edema formation after injuries or surgery, and increased or decreased muscle tone for conditions like spasticity.