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CLINICAL MICROSCOPY
AMORPHOUS URATES
 These crystals have no
distinct form and
appear as sand-like
granules
microscopically.
 Macroscopically appear
as a pink sediment after
urine centrifugation
 Acid pH urine
URIC ACID CRYSTALS
 Acid pH urine
 Appear in several forms
 Multicolored when
polarized
 Diamond shape
most common form
CALCIUM OXALATE CRYSTALS
 Acid pH urine
 Most frequently
observed
crystal in urine
 Most common form is
octahedryl shape, often
referred to as an
envelope’ shape
 Multicolored when
polarized
AMORPHOUS PHOSPHATES
 These crystals have no
distinct form and
appear as
 sand-like granules
microscopically
 Macroscopically
 appear as a white
 sediment after
 urine centrifugation
 Alkaline pH urine
TRIPLE PHOSPHATE CRYSTALS
 Most frequently
observed crystal in
alkaline urine
 Colorless, 4-6 sided
 prisms
 Referred to as
‘coffin lid crystals’
AMMONIUM BIURATES
 Alkaline pH urine
 Yellow spheres with
 spicules on surface
 Referred to as ‘thorny apple
crystals’
 Significant when found in
fresh urine
 Presence indicates urine is
old
THANK YOU
SYED BASHEER UDDIN

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Clinical microscopy

  • 2. AMORPHOUS URATES  These crystals have no distinct form and appear as sand-like granules microscopically.  Macroscopically appear as a pink sediment after urine centrifugation  Acid pH urine
  • 3. URIC ACID CRYSTALS  Acid pH urine  Appear in several forms  Multicolored when polarized  Diamond shape most common form
  • 4. CALCIUM OXALATE CRYSTALS  Acid pH urine  Most frequently observed crystal in urine  Most common form is octahedryl shape, often referred to as an envelope’ shape  Multicolored when polarized
  • 5. AMORPHOUS PHOSPHATES  These crystals have no distinct form and appear as  sand-like granules microscopically  Macroscopically  appear as a white  sediment after  urine centrifugation  Alkaline pH urine
  • 6. TRIPLE PHOSPHATE CRYSTALS  Most frequently observed crystal in alkaline urine  Colorless, 4-6 sided  prisms  Referred to as ‘coffin lid crystals’
  • 7. AMMONIUM BIURATES  Alkaline pH urine  Yellow spheres with  spicules on surface  Referred to as ‘thorny apple crystals’  Significant when found in fresh urine  Presence indicates urine is old