classical swine fever

1. SAUMYA ADIYAMAAN
BVSc & AH
VCRI - UDP

2. About the disease
01
Routes of Infection
02
Pathogenesis and
its clinical signs
03
Gross lesions
04
Microscopic lesions
05
Diagnosis
06
Table of contents

3. About the
disease
01
Highly contagious disease of pig
characterized by Intestinal
disturbances, diarrhea,
pneumonia and skin hemorrhages

4. Swine fever, also known
as Hog cholera or Swine
plague ,
is a disease native to
America. It is highly
contagious and its
prevalence led to the
first notice of an animal
disease by the
federal government in
1860
Introduction

5. Etiology
Only one serotype
Virus family Flaviviridae
Virus genus Pestivirus
About the disease

6. Digestive tract Respiratory tract
Conjunctiva Nasal mucosa
02 Routes of Infection

7. Incubation period :
1 to 4 days by artificial infection and 7
days in natural infection

8. The virus enters blood
Pathogenesis
Erythematous
patches of skin and
enteritis
Multiplication in
tonsillar tissue
03

9. Clinical signs
Fits Howling

10. Clinical signs
Wobbling gait Coma

11. 04 Gross Lesions
1. Intestine- Necrotic enteritis - Spherical
‘button ulcers’ – Mucosa of Caecum and Colon.

12. 2. Skin - Erythematous patches in the ventral
surface of the abdomen and thorax, ears, inner
aspects of thigh, perineum and snout

13. 3. Kidney – Subcapsular hemorrhages and
renal cortex shows “ Turkey egg ”
appearance due to petechiae.

14. 4. Spleen - Splenic infarcts

15. 5. Lymph node - Swollen lymph node and
red in color.

16. 05 Microscopic lesion
Haemorrhages may be seen in the bowman's
space and interstitial areas.
Button ulcer - Occurs due to infarction,
develops following occlusion of small
arterioles by swelling and hydropic changes in
its endothelium.
Splenic infarcts.
Disseminated non-purulent meningo-
encephalomyelitis.
Croupous pneumonia

17. History Symptoms
Lesions Laboratory
testing
06 Diagnosis

18. Laboratory testing:
Agar gel precipitation test
Fluorescent antibody
technique

19. Thank You !