This paper discusses a comparative study of reinforced concrete (R.C.C.) and steel-concrete composite multistoried buildings, specifically focusing on a G+15 office building in an earthquake zone. The study employs structural analysis using STAAD-Pro software to evaluate various performance metrics such as deflection, moment, and cost efficiency, revealing that composite structures are more economical and provide better seismic performance. Results suggest significant advantages in construction speed and material savings for composite systems, highlighting their growing importance in modern engineering.