This document summarizes a presentation on clinically integrated networks and accountable care organizations (ACOs). It discusses: 1) The policy context and definitions of ACOs, which accept accountability for spending and quality for defined patient populations. 2) Similar past attempts at integrated care in the 1990s and lessons learned. 3) Infrastructure like electronic medical records that now enables more coordinated care compared to the past. 4) Early evidence that ACO-like models in Massachusetts reduced spending and improved quality for Medicare patients. 5) Major ongoing challenges for ACOs around aligning incentives, performance measurement, and investing to reorganize care delivery.