The document summarizes the anatomy and radiographic investigation of the thorax. It describes the structures that make up the thoracic wall and cavities. It then discusses various imaging modalities used to examine the thorax, including plain radiography, CT, MRI, PET, and others. It provides details on technical factors and positioning for chest x-rays and interpreting chest x-ray findings based on relative tissue densities.
Learn Chest X-Ray With Its Normal Positioning & Radio-AnatomyDr.Santosh Atreya
Learn Chest X-Ray With Its Normal Positioning & Radio-Anatomy..For some image description please go through the text book "David Sutton" because i have described these image during my presentation Verbally..There are many animations used inside this presentation so to see all the pictures which are placed layer by layer with the help of animations you simple need to download this presentation first.... Thanx.
Learn Chest X-Ray With Its Normal Positioning & Radio-AnatomyDr.Santosh Atreya
Learn Chest X-Ray With Its Normal Positioning & Radio-Anatomy..For some image description please go through the text book "David Sutton" because i have described these image during my presentation Verbally..There are many animations used inside this presentation so to see all the pictures which are placed layer by layer with the help of animations you simple need to download this presentation first.... Thanx.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
2. Introduction-
The musculoskeletal wall of the thorax is flexible and consists
of segmentally arranged vertebrae, ribs, muscles, and the
sternum.
The thoracic cavity enclosed by the thoracic wall and the
diaphragm, is subdivided into three major compartments:
• a left and a right pleural cavity, each surrounding a lung;
•mediastinum.
3. A horizontal plane passing
through the sternal angle and
the intervertebral disc between
vertebrae TIV and TV separates
the mediastinum into superior
and inferior parts .
The inferior part is further
subdivided by the pericardium,
which encloses the pericardial
cavity surrounding the heart.
The mediastinum is a thick midline partition that extends from the
sternum anteriorly to the thoracic vertebrae posteriorly, and from the
superior thoracic aperture to the inferior thoracic aperture.
7. Secondary pulmonary lobule
•smalllest discrete unit of lung tissue, polyhedral in shape, surrounded
by connective tissue septa (the interlobular septa)
•Each lobule contains up to a
dozen acini and 30-50 primary
pulmonary lobules.
•Within the secondary lobule,
separating adjacent acini is a much
less pronounced network of
supporting connective tissue which
forms the intralobular septa.
9. The plain chest film i s the most frequently requested radiological examination.
Visualisation of the lungs is excellent because of the inherent contrast of the tissues of the
thorax.
Digital radiography is a form of X-ray imaging, where digital X-ray sensors are used
instead of traditional photographic film
Instead of X-ray film, digital radiography uses a digital image capture device.
•immediate image preview and availability
•elimination of costly film processing steps
•ability to apply special image processing techniques that enhance overall display quality of
the image.
Fluoroscopy is an imaging technique that uses X-rays to obtain real-time moving images of
the interior of an object.
CT scanning i s far superior for staging malignancy, detecting pulmonary metastases, and
assessing chest wall and pleural lesions, the lung mass, the hilum and mediastinum.
HRCT scanning is of proven value in the diagnosis of diffuse lung disease, particularly in the
early stages when the chest radiograph is normal, and for follow-up.
10. Transthoracic needle biopsy (TNB) is a safe rapid method used to achieve definitive
diagnosis for most thoracic lesions, whether the lesion is located in the pleura, the lung
parenchyma, or the mediastinum. Malignant lesions are differentiated from benign
lesions by using TNB .
When a bronchogenic neoplasm is suspected, biopsy of the lesion is often needed to
determine the cell type before the course of treatment is planned.
Ultrasound is of use for investigating chest wall and pleural lesions adjacent to the
chest wall. It is used for the localisation of pleural fluid.
Pulmonary angiography remains the gold standard
for the diagnosis of pulmonary embolism.
It may also be used to help diagnose:
•AV malformations of the lung
•Congenital narrowing of the pulmonary vessels
•Pulmonary artery aneurysms
•Pulmonary hypertension
Selective left pulmonary angiogram shows abrupt
tapering of the segmental pulmonary arteries (arrow).
11. Bronchial arteriography is radiography of bronchial arteries by
selective injection of the intercostal arteries from which they arise.
Bronchial artery embolization (BAE) is one of the treatment options for
hemoptysis.
Bronchography is a radiographic (x-ray) examination of the interior
passage ways of the lower respiratory tract after coating the airways
with contrast.
Bronchography is rarely performed, as it has been made obsolete with
improvements in computed tomography and bronchoscopy.
Lymphangiography is used to visualize the lymph vessels.Chylous
reflux with the formation of a chylothorax may be demonstrated by this
procedure.
12. Magnetic resonance imaging (MRI) is an important tool in
assessment of diseases of the heart, mediastinum, pleura, and chest
wall.
Strengths of MRI include excellent tissue contrast, multiplanar
imaging capability, sensitivity to blood flow, and lack of ionizing
radiation.
MRI of the lung is less well established
Positron Emision Tomography
•PET is now the most accurate imaging technique for the staging of
primary lung tumors
•Intravenously administered deoxyglucose labelled with fluorine-18
(FDG) accumulates in metabolically active cells as FDG-6-phosphate.
•FDG uptake correlates with the level of glycolylic activity in the cell,
and this is itself an indicator of the rate of cell growth and the degree
of malignancy of tumours.
13. V/Q (ventilation/perfusion) scan is a scintigraphic examination of the lung
that evaluates pulmonary vasculature perfusion and segmental bronchoalveolar tree
ventilation.
Indications
•suspected pulmonary embolism(PE)
•monitor pulmonary function following lung transplant
•provide preoperative estimates of lung function in lung cancer patients, where
pneumonectomy is planned
In the ventilation phase of the test, a gaseous
radionuclide such
as xenon or technetium DTPA in an aerosol
form is inhaled by the patient through a
mouthpiece or mask that covers the nose and
mouth.
The perfusion phase of the test involves the
intravenous injection of radioactive technetium
macro aggregated albumin(Tc99m-MAA).
A gamma camera acquires the images for both
phases of the study.
14. Scheme for viewing the PA film
1. Request form - Name, age, date, sex,Clinical information
2. Technical - Adequate inspiration
Centring, patient position/rotation
Side markers
Exposure/adequate penetration
3. Trachea - Position, outline
4. Heart and mediastinum - Size, shape, displacement
5. Diaphragms - outline, shape, Relative position
6. Pleural spaces - Position of horizontal fissure
Costophrenic, cardiophrenic angles
15. 7. Lungs - Local, generalised abnormality
Comparison of the translucency and
vascular markings of the lungs
8. Hidden areas -Apices, posterior sulcus, mediastinum, hila, bones
9. Hila -Density, position, shape
1 0. Below diaphragms- Gas shadows, calcification
11. Soft tissues - Mastectomy, gas, densities, etc.
1 2. Bones- Destructive lesions, etc
16.
17. X-rays are a form of electromagnetic radiation
with wavelengths shorter than visible light.
Unlike visible light, radiation passes through stuff.
When you shine a beam of X-Ray at a person
and put a film on the other side , a shadow is
produced of the inside of their body.
Different tissues in our body absorb X-rays
at different extents.
18. Relative Densities
The images seen on a chest radiograph result from the
differences in densities of the materials in the body.
The hierarchy of relative densities from least dense (dark on the
radiograph) to most dense (light on the radiograph) include:
Gas (air in the lungs)
Fat (fat layer in soft tissue)
Water (same density as heart and blood vessels)
Bone (the most dense of the tissues)
Metal (foreign bodies)
19.
20. Three Main Factors Determine the
Technical Quality of the Radiograph
Inspiration
Penetration
Rotation
21. Inspiration
The chest radiograph should be obtained with the patient in
full inspiration to help assess intrapulmonary abnormalities.
At full inspiration, the diaphragm should be observed at about
the level of the
8th to 10th rib posteriorly, or
5th to 6th rib anteriorly.
22.
23. Penetration
On a properly exposed chest radiograph:
The lower thoracic vertebrae should be visible through the
heart
The bronchovascular structures behind the heart (trachea,
aortic arch, pulmonary arteries, etc.) should be seen
24. Underexposure
cardiac shadow is opaque,
with little or no visibility of
the thoracic vertebrae.
The lungs may appear much
denser and whiter, much as
they might appear with
infiltrates present.
25. Overexposure
heart becomes more
radiolucent
lungs become proportionately
darker.
the air-filled lung periphery
becomes extremely radiolucent,
and often gives the appearance
of lacking lung tissue, as would
be seen in a condition such as
emphysema.
26. Rotation
Assessed by observing the clavicular heads and determining
whether they are equal distance from the spinous processes of the
thoracic vertebral bodies.
27. Four major positions are utilized for
producing a chest radiograph:
Posterior-anterior (PA)
Lateral
Anterior-posterior (AP)
Lateral Decubitus
28. Posterioranterior (PA) Position
The standard position for obtaining a routine adult chest
radiograph
Patient stands upright with the anterior chest placed against
the front of the film
The shoulders are rotated forward enough to touch the film,
ensuring that the scapulae do not obscure a portion of the
lung fields
Usually taken with the patient in full inspiration
The PA film is viewed as if the patient is standing in front of
you with his/her right side on your left
29.
30. Lateral Position
Patient stands upright with the left side of the chest against
the film and the arms raised over the head
Allows the viewer to see behind the heart and diaphragmatic
dome
Is typically used in conjunction with a PA view of the same
chest to help determine the three-dimensional position of
organs or abnormal densities
32. Anteriorposterior (AP) Position
Used when the patient is debilitated, immobilized, or unable
to cooperate with the PA procedure
The film is placed behind the patient’s back with the patient
in a supine position
Because the heart is at a greater distance from the film, it will
appear more magnified than in a PA
The scapulae are usually visible in the lung fields because
they are not rotated out of the view as they are in a PA
33.
34. Lateral Decubitus Position
The patient lies on either the
right or left side
The radiograph is labeled
according to the side that is
placed down
Often useful in revealing a
pleural effusion that cannot be
easily observed in an upright
view
35. •The AP lordotic chest radiograph demonstrates areas of the
lung apices that appear obscured on the PA/AP chest views.
•used to evaluate suspicious areas within the lung apices
LORDOTIC VIEW
36. Anatomical Structures in the Chest
Mediastinum
Hilum
Lung Fields
Diaphragmatic Domes
Pleural Surfaces
Bones
Soft Tissue
37.
38. Mediastinum
The trachea should be centrally located or slightly to the right
The aortic arch is the first convexity on the left side of the
mediastinum
The pulmonary artery is the next convexity on the left, and
the branches should be traceable as it fans out through the
lungs
The lateral margin of the superior vena cava lies above the
right heart border
39. The Heart
Two-thirds of the heart should lie on the left side of the chest,
with one-third on the right
The heart should take up less that half of the thoracic cavity
(C/T ratio < 50%)
The left atrium and the left ventricle create the left heart
border
The right heart border is created entirely by the right atrium
(the right ventricle lies anteriorly and, therefore, does not
have a border on the PA)
40. The cardiac diameter should be the maximum cardiac diameter(r+l).
The transeverse thoracic diameter is measured as the maximum internal
diameter of the thorax.
41.
42. Hilum
The hila consist primarily of the major
bronchi and the pulmonary veins and
arteries
Only the pulmonary arteries &
upper lobe veins contribute
significantly to the hilar shadows
Left pulmonary artery lies above the
left main bronchus, where as on right
side artery is anterior to bronchus
resulting in right hilum being the
lower
Both hila should be of similar size and
density
43. Lungs
Normally, there are visible markings throughout the lungs
due to the pulmonary arteries and veins, continuing all the
way to the chest wall
Both lungs should be scanned, starting at the apices and
working downward, comparing the left and right lung fields
at the same level (as is done with ascultation)
44.
45. Lungs
On a PA radiograph, the horizontal fissure can often be seen
as a faint horizontal line dividing the RML from the RUL.
The oblique fissures are not usually seen on a PA view because
they are being viewed obliquely.
All fissures are clearly seen on the lateral film.
The horizontal fissure runs anteriorly and often slightly
downward.
Both oblique fissures commence posteriorly at the level of T4
or T5, passing through the hilum. The left is steeper and
finishes 5 cm behind the anterior costophrcnic angle. whereas
the right ends just behind the angle.
46.
47.
48.
49.
50.
51.
52. Diaphragm
The left dome is normally
slightly lower than the right due
to the heart depressing the left
side.
The costophrenic recesses are
formed by the hemidiaphragms
and the chest wall.
Margins should be sharp
53. Pleura
The pleura and pleural spaces will only be visible when there is an
abnormality present
Common abnormalities seen with the pleura include pleural
thickening, or fluid or air in the pleural space.
54. Soft Tissue
Thick soft tissue may obscure underlying structures:
Thick soft tissue due to obesity may obscure some underlying
structures such as lung markings
Breast tissue may obscure the costophrenic angles
Lucencies within soft tissue may represent gas (as observed
with subcutaneous air)
55. Bones
The bones visible in the chest radiograph include:
Ribs
Clavicles
Scapulae
Vertebrae
Proximal humeri
The bones are useful as markers to assess patient rotation,
adequacy of inspiration, and x-ray penetration.
56. Describing Abnormal Findings on a
Chest Radiograph
When addressing an abnormal finding on a chest radiograph,
only a description of what is seen, rather than a diagnosis,
should be presented (a chest radiograph alone is NOT
diagnostic, but is only one piece of descriptive information
used to formulate a diagnosis)
Descriptive words such as shadows, density, or patchiness,
should be used to discuss the findings
58. Silhouette Sign
The loss of the lung/soft tissue interface due to the presence
of mass or fluid in the normally air-filled lung
If an intrathoracic opacity is in anatomic contact with a
border, then the opacity will obscure that border.
Commonly seen with the borders of the heart, aorta, chest
wall, and diaphragm.
59. Lobe Silhouetted structure
Right middle lobe Right heart border
Left lingula Left heart border
Right lower lobe Right hemidiaphragm
Left lower lobe Left hemidiaphragm
Post apical segment left upper lobe Aortic knob
Ant segment right upper lobe Ascending aorta
Silhouette Sign
61. Air Bronchogram
A tubular outline of an airway made visible due to the filling of the
surrounding alveoli by fluid or inflammatory exudates.
It is an important sign showing that an opacity is intrapulmonary.
Conditions in which air bronchograms are seen:
Normal expiration
Lung consolidation
Pulmonary edema
Hyaline membrane disease
Lymphoma
Alveolar cell carcinoma
ARDS
63. This patient has bilateral lower lobe pulmonary edema. The alveoli are
filled with fluid making the bronchi visible as an air bronchogram.
64. Consolidation is the result of replacement of air in the alveoli by
transudate, pus, blood, cells or other substances.
Pneumonia is by far the most common cause of consolidation.
The disease usually starts within the alveoli and spreads from one
alveolus to another.
When it reaches a fissure the spread stops there.
The key-findings on the X-ray are:
•ill-defined homogeneous opacity obscuring vessels
•Silhouette sign: loss of lung/soft tissue interface
•Air-bronchogram
•Extention to the pleura or fissure, but not crossing it
•No volume loss
Consolidation
65. •Density in right upper lung
field
•Lobar density
•Loss of ascending aorta
silhouette
•No shift of mediastinum
•Transverse fissure not
significantly shifted
•Air bronchogram
Consolidation Right Upper Lobe
66. Atelectasis
Almost always associated with a linear increased density due to
volume loss
Direct signs
(i)opacity of the affected lobe(s)
(ii)crowding of the vessels and bronchi within the collapsed area &
(iii) displacement or bowing of the fissures
Indirect signs
(i)compensatory hyperinflation of the normal lung or lobes
(ii) displacement of the mediastinal structures toward the affected side
(iii) displacement of the ipsilateral hilum
(iv) elevation of the ipsilateral hemidiaphragm: and
(v) crowding of the ribs on the affected side, particularly common in
children.
67. Atelectasis Left Lung
•Homogenous density
left hemithorax
•Mediastinal shift to left
•Left hemithorax smaller
•Diaphragm and heart
silhouette are not
identifiable
68. Atelectasis Right
Upper Lobe
•Density in the right
upper lung field
•Transverse fissure
pulled up
•Right hilum pulled up
•Smaller right lung
•Smaller right
hemithorax
69. Right hilar mass (orange)
obstructing the right upper
lobe bronchus results in
collapse of the right upper
lobe (green arrow). This
results in a reverse S shape to
the pleural edge.
RUL collapse
Golden S sign
70. RLL collapse
when a calcified granuloma is present in a lung and a significant parenchymal collapse
shifts it from one place to other.
Shifting granuloma sign
71.
72. The Luftsichel sign
refers to the frontal chest
radiographic appearance due to
hyperinflation of the superior
segment of the left lower lobe
interposing itself between the
mediastinum and the collapsed
left upper lobe.
LUL collapse
74. Juxtaphrenic peak sign
• refers to the peaked or tented
appearance of
a hemidiaphragm.
• caused by retraction of the
lower end of diaphragm at
an inferior accessory
fissure(most common), major
fissure or inferior pulmonary
ligament.
• It is commonly seen
in upper lobe collapse but
may also be seen in middle
lobe collapse. diaphragmatic tenting
75. • Also known as folded lung or Blesovsky syndrome
•Occurs as a consequence of diseases with chronic pleural scarring, especially asbestos-
related pleural disease and TB
•Comet tail on CT: vessels and bronchi converge upon and appear to swirl around mass
•The way the lung collapses can at times give a false mass-like appearance.
Round atelectasis
76. characterized by linear shadows of increased density at the lung bases.
Usually horizontal, measure 1-3 mm in thickness and are only a few cm long.
In most cases these findings have no clinical significance and are seen in smokers and
elderly.
They are seen in patients, that are in a poor condition and who breathe superficially, for
instance after abdominal surgery (figure) or patients with rib fracture.
Plate-like atelectasis
77. Areas of decreased density in the lung as:
•Cavity - lucency with a thick wall
•Cyst - lucency with a thin wall
•Emphysema - lucency without a visible wall
80. EMPHYSEMA
Common features seen on the chest radiograph include:
•Hyperinflation with flattening of the diaphragms
•Reduction of pulmonary vascularity peripherally
•Increased retrosternal space
•Enlargement of PA/RV (cor pulmonale)
81.
82. Pleural Effusion
In the AP film, an effusion will appear as a graded haze that is
denser at the base.
A lateral decubitus film is helpful in confirming an effusion as the
fluid will collect on the dependent side
Approximately 200 ml of fluid are needed to detect an effusion in a
PA film, while approximately 75 ml of fluid would be visible in the
lateral view.
The vascular shadows can usually be seen through the effusion.
83. The most dependent recess of the pleura is the posterior costophrenic
angle. A small effusion will, therefore, tend to collect posteriorly and in
most patients 100-200 ml of fluid are required to fill this recess before
fluid will be seen above the dome of the diaphragm on the frontal view
87. Pseudotumor of Lung. Frontal and lateral views of the chest demonstrate a
lemon-shaped soft-tissue density corresponding to the location of the minor
fissure on both views . This is a classic appearance for a pseudotumor of the
lung.
88.
89. Differentiation between pleural effusion and ascites on CT scans
•Displaced crus sign
•Diaphragm sign
•Interface sign
•Bare area sign
90. Pneumothorax
Pneumothorax is presence of air in pleural cavity
It is useful to divide pneumothoraces into three categories :
1. primary spontaneous: no underlying lung disease
2. secondary spontaneous: underlying lung disease is present
3. iatrogenic/traumatic
91. Appears in the chest
radiograph as air without
lung markings
In a PA film it is usually seen
in the apices since the air
rises to the least dependent
part of the chest
The air is typically found
peripheral to the white line of
the visceral pleura
Best demonstrated by an
expiration film
92.
93. The deep sulcus sign on
a supine chest radiograph
is an indication of
a pneumothorax.
The costophrenic angle is
abnormally deepened
when the pleural air
collects laterally,
producing the deep sulcus
sign.
94. ULTRASOUND-
Visualising the junction between sliding lung and absent sliding is known
as the lung point sign and is near 100% specific for pneumothorax and
also gives an indication of pneumothorax size by its location.
On M mode, classical signs for the gray scale imaging are seen:
•seashore sign: normal lung sliding
•barcode/stratosphere sign: pneumothorax
95.
96. CT is considered the gold-standard in the diagnosis of pneumothorax.
102. Pulmonary Edema
There are two basic types of pulmonary edema:
Cardiogenic pulmonary edema caused by increased
hydrostatic pulmonary capillary pressure
Noncardiogenic pulmonary edema caused by either altered
capillary membrane permeability or decreased plasma
oncotic pressure
103. Cardiogenic pulmonary edema Non-cardiogenic pulmonary edema
Patchy infiltrates in bases Homogenous infiltrates
Pleural effusion No pleural effusion
Cardiomegaly Normal size heart
Kerley B lines No kerley b lines
104. Congestive Heart Failure
Common features observed on the chest radiograph of a CHF
patient include:
Cardiomegaly (cardiothoracic ratio > 50%)
Cephalization of the pulmonary veins
Appearance of Kerley B lines
Alveolar edema often present in a classis perihilar bat wing
pattern of density
105. chest x-ray of a patient
in severe CHF
•cardiomegaly
•alveolar edema
•haziness of
vascular margins
106. Kerley B Lines
Transverse non-branching 1-2 mm lines at the lung bases
perpendicular to the pleura 1-3 cm long
Thickened interlobular septa
108. Primary pulmonary tuberculosis in 18-year-old boy
TUBERCULOSIS
patchy
consolidation,
nodules, and
cavities (arrows)
in bilateral upper
lung zones.
114. Invasive thymoma
Anterior mediastinum
43-year-old woman presenting with chest pain and dyspnoea. PA film (A) shows widening of the
mediastinum on the right with bilateral pleural effusions. CT scan with contrast soft-tissue
enhancement (B) at the level of the tracheal bifurcation shows an oval mass of mixed density
(arrow) in the anterior mediastinum with a small pleural mass anteriorly on the right.
Diagnosis confirmed by needle biopsy and surgery.
117. Hilum overlay sign
Differentiates large pulmonary artery from hilar mass,
mass superimposes on vessels.
Hilar vessels are seen through the mass
Lymphoma
118. Hilum convergence sign
Differentiates large pulmonary artery from hilar mass on chest x ray,
vessels converge on pulmonaary artery but go past hilar mass
119. A solitary pulmonary nodule or SPN is defined as a discrete,
well-marginated, rounded opacity less than or equal to 3
cm in diameter.
It has to be completely surrounded by lung parenchyma,
does not touch the hilum or mediastinum and
is not associated with adenopathy, atelectasis or pleural
effusion.
Lesions smaller than 3 cm, i.e. SPN's are most commonly
benign granulomas, while lesions larger than 3 cm are
treated as malignancies until proven otherwise and are
called masses.
Solitary Pulmonary Nodule-
121. A pulmonary mass is any area of pulmonary
opacification that measures more than 3cm. The
commonest cause for a pulmonary mass is lung cancer.
Corona radiata sign
Features suggestive of malignancy-
•Corona radiata sign
•Air bronchogram sign
•Nodules containing aground glass component
•Contrast enhancement >15 HU
The pericardium and heart constitute the middle mediastinum.
The anterior mediastinum lies between the sternum and the pericardium; the posterior mediastinum lies between the pericardium and thoracic vertebrae
A bronchopulmonary segment is a portion of lung supplied by a specific tertiary bronchus (also called a segmental bronchus) and arteries. Each bronchopulmonary segment is a discrete anatomical and functional unit, and this separation means that a bronchopulmonary segment can be surgically removed without affecting the function of the others.
Each secondory pulmonary lobule is supplied by a lobular bronchiole and a pulmonary artery branch. They are drained by pulmonary veins which form in the periphery of the lobule and pass through the interlobular septa.
However, the acoustic mismatch between the chest wall & air containing lung results in reflection of ultrasound beam at the lung-pleura interface , so that normal lung cannot be demonstrated.
Bronchial artery- 2 in left, 1 in right
SPINE SIGN- an abnormal increase in opacification overlying the spine while moving superior to inferior on lateral view, s/o lower lobe opacities or infiltrates
(a left lateral decubitus radiograph would have the patient’s left side down against the film)
The patient is standing with feet approximately 30cm away from the image receptor, with back arched until upper back, shoulders and head are against the image receptor.The angle formed between the midcoronal body plane and image receptor should be approximately 45 degrees
Since the large airways contain air and are therefore of lower density than the surrounding soft tissue, they should be visible on most good-quality radiographs.
The trachea may be slightly off midline to the right since it passes to the right of the aorta.
The trachea can appear deviated if the patient is rotated.
Lung roots lies opposite to the bodies of the 5th,6th & 7th thoracic vertebrae.
Shifting granuloma sign refers to a shift in the location of a parenchymal lesion visible on prior films that may be seen in the presence of atelectasis.
diaphragmatic tenting
Patient with h/o asbestos exposure.chest radiograph shows en face pleural plaque on the right calcified pleural plaques over the right dome of diaphragm(arrow heads).there is the suggestion of a right infrahilar mass.CT demonstrates indrawing of the bronchovascular structures into a pleurally based mass.
CT: Markedly dilated bronchi are seen, some with air-fluid levels (yellow arrows), mostly in the right lung.
Permanent abnormal enlargement of air spaces distal to the terminal bronchiole, accompanied by destruction of their walls without obvious fibrosis
Types – centriacinar, panacinar, paraseptal, irregular
Lung CT image showing regions of bullous emphysema destruction, pre- dominantly in the lower lobes (arrows)
Larmelar effursions are shallow collections between the lung surface and the visceral pleura. sometimes sparing the costophrenie angle. Strictly, lamellar effusions represent interstitial pulmonary fluid.
Loculated interlobar effusions can appear rounded on two views.Following treatment they may disappear rapidly, and are hence known as `pseudo-' or `vanishing' tumours. They may recur in subsequent episodes of heart failure.
Differentiation between pleural and ascitic fluid on CT scans is sometimes a problem, and may be resolved by a number of signs,
which are describe below.Displaced crus sign pleural fluid may collect posterior to the diaphragmatic crux and therefore displace the erus anteriorfy,whereas aseites collects anterior to the erus and may cause posterior displacement (Fig. 3.16A).Diaphragm sign As an extension of the displaced erus sign,any fluid that is on the exterior of the dome of the diaphragmi s in the pleura. whereas any that is within the dome is aseites( Fig. 3.16A). Interface sign The interface between the liver or spleen and pleural fluid is said to be less sharp than that between the liver or spleen and ascites (Fig. 3.16B). Bare area sign The peritoneal coronary ligament prevents ascitic fluid from extending over the entire posterior surface of the liver, whereas in a free pleural space, pleural fluid may extend overthe entire posterior costophrenic recess behind the liver( Fig. 3.16B).
In a supine film (common in the ICU), it may be the only indication of a pneumothorax because air collects anteriorly and basally, within the nondependent portions of the pleural space, as opposed to the apex when the patient is upright.
The normal lung interface with pleura shows lung sliding with vertical comet tails running down from the pleural surface. In pneumothorax, this sliding is absent and so are the comet tail artifacts from the pleura. This is due to air in between the parietal and visceral pleura, preventing lung from sliding.
Tension pneumothorax occur when intrapleural air accumulates progressively in such a way as to exert positive pressure on mediastinal and intrathoracic structures.
(A) Chest radiograph of an asymptomatic patient shows a well-circumscribed, round capacity (arrowheads) projected over the heart. (B) CT scan shows it to be a pleural mass of entirely fat density. (C) Parasagittal reconstruction of the multislice CT scan shows the mass lying above the diaphragm within theposterior costophrenic recess.
Abnormal chest radiograph (A) shows lobulated left pleural opacities. (B) CT scan through the mid thorax demonstrates encasement of the right lung by nodular pleural tumour.
In the pulmonary vasculature of the normal chest, the lower zone pulmonary veins are larger than the upper zone veins due to gravity. In a patient with CHF, the pulmonary capillary wedge pressure rises to the 12-18 mmHg range and the upper zone veins dilate and are equal in size or larger, termed cephalization.
A lines 1 -2 mm non-branching lines radiating from the hilum, 2-6 cm long,Thickened deep interlobular septa
B lines Transverse non-branching 1-2 mm lines at the lung bases perpendicular to the pleura 1-3 cm long ,Thickened interlobular septa
patchy consolidation, nodules, and cavities (arrows) in bilateral upper lung zones.
Tuberculosis, post-primary. There are large cavities in both apices and smaller cavities scattered throughout the lungs. The lungs are over-aerated and there is already scarring present. Dilated bronchi (tuberculous bronchiectasis) is present throughout the lungs.
Tuberculosis, cavitary. There is a cavity in the right upper lobe with an air-fluid level (black arrow). There is volume loss in the right upper lobe as evidenced by elevation of the minor fissure (white arrow).
haematogenous dissemination of an uncontrolled tuberculous infection. appear as 1-3 mm diameter nodules, which are uniform in size and uniformly distributed, seen both in primary and post-primary tuberculosis
Garland triad - lymph node enlargement pattern which has been described in sarcoidosis :,right paratracheal nodes,right hilar nodes,left hilar nodes
The lambda sign is seen on gallium-67 scans in the setting of thoracic sarcoidosis. Bilateral hilar and right paratracheal lymph nodes are typically involved which can resemble the lambda symbol (λ).
typical presentation of sarcoidosis with hilar lymphadenopathy and small nodules along bronchovascular bundles (yellow arrow) and along fissures (red arrows). Notice the partially calcified node in the left hilum.
On the PA film there is a lobulated widening of the superior mediastinum. On the lateral chest film the retrosternal clear space is obliterated.
Asymptomatic 21 yr old woman. PA(A) and lateral (B) films show an oval mass in the middle mediastinum below the carina on the right. Diagnosis confirmed by surgery.
Asymptomatic 57-year-old woman. PA (A) and lateral (B) films show a round mass in the posterior mediastinum behind the heart on the right. Lateral tomogram showed enlargement of the intervertebral foramen.
On the chest film there is a mass that has obtuse angles with the mediastinum, so it is a mediastinal mass.The hilar vessels are seen through this mass, so it does not arise from the hilum and probably will arise from the anterior mediastinum.The anterior location was confirmed on a CT.
Large nodule size, irregular, spiculated margins, inhomogeneous density of nodule thick walls in cavitary nodules suggest the presence of the malignant lesion. Smooth, well-defined margins, homogeneous density or the presence of diffuse, laminated, central or popcorn-like calcifications suggest the benign nodule. Diffuse, irregular amorphous calcifications suggest the malignant process.
Wave sign of mulvey- Both borders may be wavy in outline, the `wave sign of Mulvey’, as a consequence of indentation by the costal cartilages