The document summarizes developments in Italian art from 1500-1600, focusing on Rome replacing Florence as the center of the Renaissance. It discusses major artists like Leonardo, Raphael, Michelangelo and their works. Architecture is explored through figures like Bramante and Palladio. The High Renaissance gives way to Mannerism, characterized by elongated figures and less symmetry. Venetian art is summarized, known for rich color and artists like Bellini, Titian and Veronese. Key figures and their major works are identified in each time period and location.