Cervical cancer is the most common cancer affecting women in India and is caused by human papillomavirus (HPV) infection. Risk factors include having multiple sexual partners, young age of first sexual activity, and weakened immunity. Symptoms may include abnormal bleeding or discharge, but often do not appear until later stages. Diagnosis involves tests like Pap smear, biopsy, and colposcopy. Early detection through regular Pap tests can find precancerous cells before they develop into cancer. Treatment options depend on the stage, and may include LEEP, cryosurgery, hysterectomy, or simply removing the affected area. An HPV vaccine provides protection if received before first sexual activity.
Welcoming remarks by Dr Osborne E Nyandiva on Symposium: Cervical cancer and its prevention
Co-Presenter Dr Giama. We are happy to present to you this very crucial discussion on Cancer.
Cervical cancer is a type of cancer that develops in a woman's cervix (the entrance to the womb from the vagina).
Cancer of the cervix often has no symptoms in its early stages. If you do have symptoms, the most common is unusual vaginal bleeding, which can occur after sex, in between periods or after the menopause.
Welcoming remarks by Dr Osborne E Nyandiva on Symposium: Cervical cancer and its prevention
Co-Presenter Dr Giama. We are happy to present to you this very crucial discussion on Cancer.
Cervical cancer is a type of cancer that develops in a woman's cervix (the entrance to the womb from the vagina).
Cancer of the cervix often has no symptoms in its early stages. If you do have symptoms, the most common is unusual vaginal bleeding, which can occur after sex, in between periods or after the menopause.
October is 'Breast Cancer Awareness' month. Cancer is scary but we can fight it. With a little bit of proactive action and awareness, you and I may be able to save lives. Do spread the word and help make the world a better place.
Say no to cervical cancer-PUBLIC Awareness-Life Care Centre_Dr.Sharda JainLifecare Centre
Cervical Cancer in INDIA
Say no to cervical cancer
Dr.Sharda Jain
Life Care Centre
PUBLIC Awareness_Dr.Sharda Jain
HPV Infection
HPV Vaccination
Cervical Screening
SEE & TREAT Programme tp Prevent Cervical Cancer
The presentation describes various facts about breast and cervical cancer including burden of disease, survival outcomes, need for early diagnosis and screening recommendations.
Here in these slides we have explain about the Breast cancer Screening with the help of which one can get the x-ray image to identify the breast cancer and it is a mammogram which is used when one have no symptoms.
October is 'Breast Cancer Awareness' month. Cancer is scary but we can fight it. With a little bit of proactive action and awareness, you and I may be able to save lives. Do spread the word and help make the world a better place.
Say no to cervical cancer-PUBLIC Awareness-Life Care Centre_Dr.Sharda JainLifecare Centre
Cervical Cancer in INDIA
Say no to cervical cancer
Dr.Sharda Jain
Life Care Centre
PUBLIC Awareness_Dr.Sharda Jain
HPV Infection
HPV Vaccination
Cervical Screening
SEE & TREAT Programme tp Prevent Cervical Cancer
The presentation describes various facts about breast and cervical cancer including burden of disease, survival outcomes, need for early diagnosis and screening recommendations.
Here in these slides we have explain about the Breast cancer Screening with the help of which one can get the x-ray image to identify the breast cancer and it is a mammogram which is used when one have no symptoms.
Cancer of the cervix occurs when the cells of the cervix change in a way that leads to abnormal growth and invasion of other tissues or organs of the body.
Dr. Pk Das Is one of the famous and highly qualified doctor of cancer. He is a cervical cancer specialist in Delhi NCR. Consult Dr.PK Das for all cervical cancer related queries.
Primary ciliary dyskinesia (pcd) is an autosomal recessive genetic condition in which the microscopic cells in the respiratory system called cilia do not function normally.
Periventricular leukomalacia (pvl) is a form of brain damage that affects the white matter of brain, resulting in the cells in the white matter of brain either decaying or dying.
Kluver bucy syndrome is a very rare cerebral neurological disorder associated with damage to both temporal lobes resulting in abnormalities in memory, social and sexual functioning and idiosyncratic behaviours.
Hantavirus pulmonary syndrome is an infectious disease characterized by flu-like symptoms that can progress rapidly to potentially life-threatening breathing problems.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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2. Introduction of Cervical Cancer
The amplitude by which cancer is spreading across the globe is augmenting each passing day. Cancer
in multiple forms is causing approximately 12% deaths throughout the world. In India, cervical cancer
is the most common forms of cancer affecting female population. More women in India die of
cervical cancer than in any other country. When exposed to HPV (human papillomavirus), a
sexually transmitted infection women become vulnerable to cervical cancer. Initially, a woman’s
immune system blocks the virus but in certain group it survives for years and coverts some cells on
the cervix into cancer cells. More than 50% of cervical cancer cases occur in the age group 35-55.
3. Symptoms of Cervical Cancer
It’s unfortunate but you will not be able to witness any signs of cervical cancer because it doesn’t
produce any, not at an early stage. As the cancer grows, warning signs may appear:
Unusual bleeding from the vagina i.e. after intercourse, during periods or aftermenopause.
Pelvic or lower belly pain.
Pain during or after sex.
Unusual, foul or bloody vaginal discharge.
4. • An increase in number of sexual partners or an increase in number of your partner’s sexual
partners can leave on the bad side of HPV.
• Having sex before you hit 18 increases your chances of acquiring HPV because under-developed
cells are subject to the precancerous changes that HPV can cause.
• If you have sexually transmitted diseases like gonorrhea, HIV/AIDS or Chlamydia, you are at an
increased chance of procuring HPV.
• Women with stronger immune system are less likely to develop cervical cancer. However, if your
immune system is weakened by some other health complication, you may be more likely to
develop HPV.
Causes of Cervical Cancer
5. Diagnosis of Cervical Cancer
•Your gynecologist will perform an examination named colposcopy wherein she’ll use a colposcope to
examine abnormal cells of the cervix. She may take a sample of those unusual cells for further analysis.
•After taking the sample, the doctor performs a procedure called Biopsy where he or she uses a circular
knife to remove a small part of cervix. Different kinds of biopsies may be performed according to the
location of cancer cells.
•Conization or cone biopsy allows your doctor to examine deeper layers of cervical cells that may be
required for lab testing.
6. Pap Test
Pap test is the best available method to detect precancerous conditions and small tumors
that may cause cervical cancer. In the test, the doctor uses a device named speculum to wide
open the vagina so that the cervix can be examined. Using a plastic spatula and small brush,
he collects cells from the cervix and puts them into a solution. The solution is then sent for
laboratory testing. It usually takes about a week for results to come. A normal pap
test means cervical cells are normal. An abnormal pap test means cervical cells may contain
cancerous cells. The test is not painful but can be discomforting.
Available Treatments for cervical cancer
When cervical cancer is restricted to the outside section of cervix, it is treated by simply
removing the area dominated by cancer cells. No additional treatment is needed in such
cases. However, if cancer cells lay in the interior section of cervix then Loop electrosurgical
excision procedure (LEEP), Cryosurgery andHysterectomy are available options now a days.
Cervical cancer vaccine
Yes, it is possible to reduce the impact of cervical cancer worldwide if women go through
HPV immunization at an early stage. Three periodical doses starting as early as 9 years of age
can give the necessary protection against cervical cancer. However, cervical cancer
vaccination is not recommended for severely ill and pregnant women.